JP2009501001A - 多価ウイルス様粒子の製造 - Google Patents
多価ウイルス様粒子の製造 Download PDFInfo
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- JP2009501001A JP2009501001A JP2008514849A JP2008514849A JP2009501001A JP 2009501001 A JP2009501001 A JP 2009501001A JP 2008514849 A JP2008514849 A JP 2008514849A JP 2008514849 A JP2008514849 A JP 2008514849A JP 2009501001 A JP2009501001 A JP 2009501001A
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- virus
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- capsid fusion
- fusion peptide
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K39/00—Medicinal preparations containing antigens or antibodies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/14011—Bromoviridae
- C12N2770/14022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/14011—Bromoviridae
- C12N2770/14023—Virus like particles [VLP]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Genetics & Genomics (AREA)
- Virology (AREA)
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- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| US68654105P | 2005-06-01 | 2005-06-01 | |
| PCT/US2006/021262 WO2007053188A2 (en) | 2005-06-01 | 2006-06-01 | Production of multivalent virus like particles |
Publications (2)
| Publication Number | Publication Date |
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| JP2009501001A true JP2009501001A (ja) | 2009-01-15 |
| JP2009501001A5 JP2009501001A5 (enExample) | 2009-07-09 |
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| JP2008514849A Pending JP2009501001A (ja) | 2005-06-01 | 2006-06-01 | 多価ウイルス様粒子の製造 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20070041999A1 (enExample) |
| EP (1) | EP1885394A4 (enExample) |
| JP (1) | JP2009501001A (enExample) |
| KR (1) | KR20080018176A (enExample) |
| CN (1) | CN101287489A (enExample) |
| AU (1) | AU2006309286A1 (enExample) |
| BR (1) | BRPI0611336A2 (enExample) |
| CA (1) | CA2608515A1 (enExample) |
| WO (1) | WO2007053188A2 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100021391A1 (en) * | 2006-07-14 | 2010-01-28 | Montana State University | Novel nanoparticles for biofilm targeting |
| AU2007303608B2 (en) | 2006-09-29 | 2013-05-02 | Takeda Vaccines, Inc. | Norovirus vaccine formulations |
| WO2009033004A1 (en) * | 2007-09-07 | 2009-03-12 | Montana State University | Protein cages and their uses |
| CN101918028B (zh) | 2007-09-18 | 2015-01-07 | 莱戈赛特医药股份有限公司 | 赋予针对诺如病毒的保护性免疫应答的疫苗 |
| US20100266636A1 (en) | 2007-09-18 | 2010-10-21 | Ligocyte Pharmaceuticals, Inc. | Method of conferring a protective immune response to norovirus |
| JP5758385B2 (ja) * | 2009-06-19 | 2015-08-05 | アイジェン インコーポレーテッド | 子宮頸がんワクチン |
| EP2591097A1 (en) | 2010-07-06 | 2013-05-15 | Novartis AG | Norovirus derived immunogenic compositions and methods |
| DK3299030T3 (da) | 2011-07-11 | 2022-09-05 | Takeda Vaccines Inc | Parenterale norovirus-vaccineformuleringer |
| HUE035753T2 (hu) * | 2012-05-11 | 2018-08-28 | Medicago Inc | Rotavírusszerû részecskék termelése növényekben |
| EP3608401A1 (en) | 2012-07-05 | 2020-02-12 | Ohio State Innovation Foundation | Compositions and methods related to viral vaccines |
| US10086062B2 (en) | 2012-07-05 | 2018-10-02 | Ohio State Innovation Foundation | Infectious pancreatic necrosis virus (IPNV) vaccine compositions |
| EP3089755A1 (en) * | 2014-01-03 | 2016-11-09 | Fundacion Biofisica Bizkaia | VLPs, METHODS FOR THEIR OBTENTION AND APPLICATIONS THEREOF |
| WO2015191546A2 (en) * | 2014-06-10 | 2015-12-17 | The Board Of Regents Of The University Of Texas System | Adp-ribose detection reagents |
| CN105018463A (zh) * | 2015-06-05 | 2015-11-04 | 北京百迈客生物科技有限公司 | 一种用于次生代谢物含量高的植物组织的dna提取方法 |
| KR101830792B1 (ko) * | 2016-01-27 | 2018-02-21 | 건국대학교 산학협력단 | 항균 펩타이드를 포함하는 불용성 융합단백질 및 이를 이용한 항균 펩타이드의 제조 방법 |
| CN108558990A (zh) * | 2018-01-05 | 2018-09-21 | 山东省科学院生态研究所 | 肿瘤靶向肽f3修饰的豇豆褪绿斑驳病毒样颗粒的构建、表达及其应用 |
| WO2021108202A1 (en) * | 2019-11-25 | 2021-06-03 | The Regents Of The University Of California | Modified viral therapeutics and uses thereof |
| CN117098553A (zh) * | 2020-11-11 | 2023-11-21 | 加州理工学院 | 多价载体和相关疫苗组合物 |
| CN115747170B (zh) * | 2022-08-29 | 2023-08-04 | 四川大学 | 一种豇豆褪绿斑驳病毒-多肽复合物及其在骨质疏松治疗中的应用 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6514948B1 (en) * | 1999-07-02 | 2003-02-04 | The Regents Of The University Of California | Method for enhancing an immune response |
| JP2003534771A (ja) * | 1999-10-14 | 2003-11-25 | ザ ダウ ケミカル カンパニー | 外来性内部エピトープをもつウィルス粒子 |
| WO2003103605A2 (en) * | 2002-06-07 | 2003-12-18 | Large Scale Biology Corporation | Flexible vaccine assembly and vaccine delivery platform |
| US20040121465A1 (en) * | 2002-02-14 | 2004-06-24 | Novavax, Inc. | Optimization of gene sequences of virus-like particles for expression in insect cells |
| WO2005067478A2 (en) * | 2003-12-01 | 2005-07-28 | Dow Global Technologies Inc. | Recombinant icosahedral virus like particle production in pseudomonads |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4511503A (en) * | 1982-12-22 | 1985-04-16 | Genentech, Inc. | Purification and activity assurance of precipitated heterologous proteins |
| GB9108386D0 (en) | 1991-04-19 | 1991-06-05 | Agricultural Genetics Co | Modified plant viruses as vectors |
| GB9414118D0 (en) * | 1994-07-13 | 1994-08-31 | Axis Genetics Ltd | Modified plant viruses as vectors of heterologous peptides |
| US6042832A (en) | 1996-08-28 | 2000-03-28 | Thomas Jefferson University | Polypeptides fused with alfalfa mosaic virus or ilarvirus capsid proteins |
| EP1700911B1 (en) * | 1997-09-05 | 2016-04-06 | Medimmune, Inc. | In vitro method for disassembly/reassembly of papillomavirus virus-like particles (VLPs) |
| US6171591B1 (en) * | 1997-12-08 | 2001-01-09 | Pentamer Pharmaceuticals, Inc. | Recombinant nodavirus compositions and methods |
| KR100312456B1 (ko) * | 1999-03-13 | 2001-11-03 | 윤덕용 | 슈도모나스 플루오레슨스 유래의 외래단백질 분비촉진유전자 |
| US7135282B1 (en) * | 1999-10-14 | 2006-11-14 | The Dow Chemical Company | Viral particles with exogenous internal epitopes |
| US6552006B2 (en) * | 2000-01-31 | 2003-04-22 | The Regents Of The University Of California | Immunomodulatory polynucleotides in treatment of an infection by an intracellular pathogen |
| US20030050268A1 (en) * | 2001-03-29 | 2003-03-13 | Krieg Arthur M. | Immunostimulatory nucleic acid for treatment of non-allergic inflammatory diseases |
| AU2003221704A1 (en) * | 2002-04-08 | 2003-10-27 | Siga Technologies, Inc. | Immunogenic peptides, and method of identifying same |
| DK1523329T3 (da) | 2002-07-05 | 2013-10-14 | Folia Biotech Inc | Viruspartikeladjuvant |
| WO2005005614A2 (en) | 2003-07-03 | 2005-01-20 | Pecos Labs, Inc. | Combined b-cell and t-cell epitopes on vlp for improved vaccines |
| JP2009513532A (ja) * | 2003-07-10 | 2009-04-02 | サイトス バイオテクノロジー アーゲー | パッケージ化ウイルス様粒子 |
-
2006
- 2006-06-01 EP EP06844120A patent/EP1885394A4/en not_active Withdrawn
- 2006-06-01 CA CA002608515A patent/CA2608515A1/en not_active Abandoned
- 2006-06-01 WO PCT/US2006/021262 patent/WO2007053188A2/en not_active Ceased
- 2006-06-01 CN CNA2006800196237A patent/CN101287489A/zh active Pending
- 2006-06-01 BR BRPI0611336-2A patent/BRPI0611336A2/pt not_active IP Right Cessation
- 2006-06-01 KR KR1020077028015A patent/KR20080018176A/ko not_active Withdrawn
- 2006-06-01 US US11/444,827 patent/US20070041999A1/en not_active Abandoned
- 2006-06-01 JP JP2008514849A patent/JP2009501001A/ja active Pending
- 2006-06-01 AU AU2006309286A patent/AU2006309286A1/en not_active Abandoned
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6514948B1 (en) * | 1999-07-02 | 2003-02-04 | The Regents Of The University Of California | Method for enhancing an immune response |
| JP2003534771A (ja) * | 1999-10-14 | 2003-11-25 | ザ ダウ ケミカル カンパニー | 外来性内部エピトープをもつウィルス粒子 |
| US20040121465A1 (en) * | 2002-02-14 | 2004-06-24 | Novavax, Inc. | Optimization of gene sequences of virus-like particles for expression in insect cells |
| WO2003103605A2 (en) * | 2002-06-07 | 2003-12-18 | Large Scale Biology Corporation | Flexible vaccine assembly and vaccine delivery platform |
| WO2005067478A2 (en) * | 2003-12-01 | 2005-07-28 | Dow Global Technologies Inc. | Recombinant icosahedral virus like particle production in pseudomonads |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1885394A2 (en) | 2008-02-13 |
| US20070041999A1 (en) | 2007-02-22 |
| CA2608515A1 (en) | 2007-05-10 |
| EP1885394A4 (en) | 2009-10-21 |
| KR20080018176A (ko) | 2008-02-27 |
| BRPI0611336A2 (pt) | 2010-08-31 |
| CN101287489A (zh) | 2008-10-15 |
| AU2006309286A1 (en) | 2007-05-10 |
| WO2007053188A2 (en) | 2007-05-10 |
| WO2007053188A3 (en) | 2007-12-06 |
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