JP2009084157A - Method for producing oil and fat-coated powder - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a method for producing an oils and fats-coated powder covering taste components sufficiently, and excellent in masking effect, taste, tablet-forming property and also in preservation stability. <P>SOLUTION: This method for producing the oils and fats-covered powder containing the taste components comprises the following (A) to (C) processes. (A) A process of covering zein on the powder containing the taste components. (B) A process of obtaining the covered powder by colliding hydrogenated oils and fats powder having 1 to 50 μm mean particle diameter, 50 to 80°C melting point and ≤0.6 peak intensity ratio (19°/21° intensity ratio) of the peak intensity at 2θ (19°) to the peak intensity at 2θ (21°) in X-ray diffraction measurements by using CuKα beam as a light source to the zein-coated powder in a condition that the powder temperature becomes ≤45°C. (C) A process of tempering the covered powder prepared by the above process (B) at 35 to 60°C for 1 to 200 hr. <P>COPYRIGHT: (C)2009,JPO&INPIT

Description

  The present invention relates to a method for producing a fat-and-oil coated powder as a taste component. Specifically, it is a method for producing an oil-coated powder in which zein and fat are coated on a taste component, and a method for producing an oil-coated powder excellent in taste masking, touch, storage stability and tableting properties. provide.

  In general, herbal medicines, pharmaceuticals, health foods, and the like have a difficulty that they are difficult to take because of their bitterness, puffiness and the like inherent in their active ingredients. Therefore, as a method for masking the taste, a method of coating the taste component powder by contacting and colliding with a hardened fat powder having a melting point of 40 ° C. or higher (Patent Document 1), a taste component having a particle size of 50 μm or less is gelatin or the like. After granulating using a water-soluble binder, a method of coating the hardened oil and fat fine powder (Patent Document 2), agglomerates containing a taste component are stirred and granulated with an excipient and an oil and fat, and zein (Patent Document 3) and the like.

However, according to the production method of Patent Document 1, a sufficient masking effect has not been obtained, and since it has a strong taste, it has not been easy to take. This is probably because the coating with fats and oils sufficient to mask the taste is not performed in the fat coating process in which the fat and oil powder collides. In addition, according to the production method of Patent Document 2, the taste component is granulated with a water-soluble binder such as gelatin before the oil coating. Even in this case, a sufficient masking effect by the oil coating is obtained. Was not reached.
Moreover, in the manufacturing method in patent document 1 and 2, there existed problems, such as tableting property falling in the fat-and-oil coating powder manufactured, and adhering at the time of long-term storage. This is considered to be because the oil and fat in the outermost layer is structurally easy to fuse, and the tableting performance when used with raw materials such as tablets and the long-term storage stability of the powder are insufficient.
In addition, in the manufacturing method (patent document 3) which coat | covers outermost layers with proteins, such as zein, the particle size of a granulated material tends to become large. In addition, Zein's peculiar feeling of tongue remains and it is not suitable for taking. Furthermore, the granulation process is repeated, and the production efficiency is poor.

JP 63-164863 A JP-A-11-308985 JP-A-6-24963

An object of this invention is to provide the manufacturing method of the oil-and-oil covering powder which can fully coat | cover a taste component and was excellent also in the masking effect, the touch, tableting property, and storage stability.
Therefore, first, in the present invention, it was found that when a taste ingredient is coated with zein and further coated with oils and fats, a coating powder with excellent taste masking effect and good touch can be produced.
Next, the present invention focused on the polymorphs of the fats and oils coating the powder.
An essential attribute of fats and oils is polymorphism, and triacylglycerol usually has several types of crystal polymorphs. Their classification and nomenclature are based on the melting point and sublattice as follows: Are organized.
α type ・ ・ ・ Hexagonal (H) type sublattice, unstable type β ′ type ・ ・ O⊥ type sublattice, metastable type β type ... T // type sublattice, stable type If a regular α-type oil and fat powder is used and the tablet polymorphism is changed from the α-type to the stable β-type during tableting and storage, the tableting and storage stability can be improved.
In addition, the transition from α-type to β-type is known as solid-phase transition, and if it is an oil with a melting point of 50 to 80 ° C., it can be left over at a temperature of 10 to 30 ° C. or less over time. Transition.

A general method for identifying these polymorphs is an X-ray diffraction method, and diffraction conditions are given by the following Blacks equation.
2 d sin θ = nλ (n = 1, 2, 3,...)
A diffraction peak appears at a position satisfying this equation. Here, d is a lattice constant, θ is a diffraction (incident) angle, λ is an X-ray wavelength, and n is a natural number. From 2θ = 16 to 27 ° of the diffraction peak corresponding to the short face interval, information on the side packing (sublattice) in the crystal can be obtained, and polymorphism can be identified, particularly in the case of triacylglycerol. A characteristic peak of β type appears at 2θ = 19, 23, 24 °, and a characteristic peak of α type appears at 21 °. However, CuKα rays (1.54 Å) are most often used as an X-ray light source.
In the present invention, based on these findings, the polymorph of the oil / fat powder to be coated is converted into a β-type characteristic peak 2θ = 19 ° peak intensity ratio and an α-type characteristic peak intensity ratio (19 ° / 21 degree intensity ratio) was used to represent the polymorphic state. When this ratio is 0.6 or less, it corresponds to the case where the α-type ratio in the polymorph is 50% or more.
And when the polymorph of the oil / fat powder is α-type and the polymorph of the coated oil / fat is transferred to β-type, the coated powder with excellent masking effect, touch, tableting and storage stability is produced. The present invention has been completed by finding out what can be done.

The present invention includes the following inventions (1) and (2).
(1) A method for producing an oil-coated powder comprising the following steps (A) to (C) and containing a taste component.
(A) The process of coat | covering zein on the powder containing a taste component.
(B) The zein-coated powder obtained in the step (A) has an average particle diameter of 1 to 50 μm, a melting point of 50 to 80 ° C., and 2θ (19 °) in X-ray diffraction measurement using CuKα rays as a light source. Hardened oil and fat powder having a peak intensity ratio (19 ° / 21 ° intensity ratio) of peak intensity and 2θ (21 °) of 0.6 or less is collided under a condition that the powder temperature is 45 ° C. or less. Obtaining step.
(C) A step of tempering the coating powder obtained in the step (B) at 35 to 60 ° C. for 1 hour to 200 hours.

  An oil-coated powder having an average particle size of 100 to 300 μm obtained by the production method of (1).

  ADVANTAGE OF THE INVENTION According to this invention, the manufacturing method of the fat-and-oil covering powder which can fully coat | cover a taste component and was excellent also in the masking effect, the touch, the tableting property, and the storage stability can be provided.

The present invention is characterized by including the following steps (A) to (C).
(A) Process (A) Process in this invention is a process of coat | covering a taste component with zein, in order to make the oil-fat coating | coating in (B) process easy about a taste component.
The taste component used in the present invention is not particularly limited as long as it is a powder that gives a taste, and includes herbal medicines, vitamin Bs, herbs, bitterness components such as glucosamine and L-leucine, citric acid, malic acid and the like. It is a powder that makes you feel the taste of sour ingredients, sugar, stevia, etc. The taste component of the present invention may be a powder of the taste substance itself or a powder containing a taste substance in a powder such as dextrin or starch.
The average particle size of the powder is preferably 1 to 300 μm. If it is smaller than 1 μm, the surface area is large and the effect of zein coating is reduced, and if it is larger than 300 μm, the final touch of the oil-coated powder produced is adversely affected. If it is larger than 300 μm, it may be used after being pulverized to a desired particle size.

In the present invention, zein is used as a coating material. Zein is a protein derived from corn and has a molecular weight of 21,000-25,000. Examples of commercially available products include Kobayashi Zein DP (Kobayashi Fragrance Co., Ltd.). The coating amount of zein is preferably 4 to 25% by mass of the zein-coated powder obtained in step A. When the amount is less than 4% by mass, the coating is not sufficient, and the taste masking effect is insufficient even when the oil or fat is coated. On the other hand, when the amount is more than 25% by mass, the tablet hardness is lowered when tableting is performed using the produced oil-coated powder, which is not preferable.
Zein is a film material that dissolves in alcohol and is more compatible with fats and oils than other water-soluble substances used for granulation and binding, such as gelatin, and is suitable for later fat coating.

  In the present invention, when medium chain triglyceride is used, the coating effect of zein is enhanced and the taste masking effect is increased. Here, the medium chain triglyceride is an oil and fat compound in which a fatty acid having 8 to 10 carbon atoms is esterified to a glycerin skeleton, and examples thereof include caprylic acid triglyceride and capric acid triglyceride. The medium chain triglyceride used in the present invention is preferably a medium chain triglyceride having both C8 and C10 fatty acids. Examples of commercially available medium-chain triglycerides include Panacet 810 (trade name, Nippon Oil & Fat Co., Ltd.), Coconut MT (trade name, Kao Corporation), and the like. The amount of medium chain triglyceride used is preferably 0.1 to 20% by weight of the amount of zein used. When it is less than 0.1% by mass, the taste masking effect is lowered. On the other hand, when it is more than 20% by mass, agglomerates are formed during the zein coating in the step A.

  The manufacturing method of the (A) process of this invention sprays ethanol aqueous solution so that it may become 4-25 mass% of zein on the surface of powder 75-96 mass% containing a taste component.

  When zein is coated on the surface of a powder containing a taste component, an aqueous ethanol solution of zein is sprayed with a powder fluidized with fluidized air in a processing vessel using a rolling fluidized bed coating apparatus. It is preferable. When using a medium chain triglyceride, it is preferable to add it to an aqueous ethanol solution of zein.

The rolling fluidized bed coating apparatus is a fluidized bed coating apparatus in which a rotating disk is installed at the lower part of the apparatus. The powder is fluidized by the air flowing in from the lower part of the apparatus, and further moves by rolling the inner wall of the fluidized bed by applying a centrifugal force of the rotating disk. Compared to the normal fluid state, granulation due to the binding of powder is suppressed, and the powder can be coated efficiently. Any device capable of spray drying the zein solution may be used. Examples of commercially available devices include “Product Name: New Mullerer” manufactured by Dalton Co., Ltd. and “Product Name: Multiplex” manufactured by POWREC. Is mentioned. Furthermore, it is preferable that a conical cone portion and a plurality of blades are provided on the upper surface of the rotating disk. Due to the rolling compaction action by the blade, the generation of aggregates is suppressed, and a coated powder having a sharp particle size distribution can be obtained. Further, the coating film is subjected to a spreading action, and a uniform and high coated powder can be obtained.
The spray method is preferably a tangential spray method in which a spray liquid is sprayed in a tangential direction (rotating direction of the rotating disk) from the side surface below the apparatus to the flow of the powder rolling on the rotating disk. The spray method used in a general fluidized bed granulator is a top spray method in which droplets are sprayed downward from the top of the fluidized powder, while the tangential spray method is used in the coating zone. Since the spray liquid can be sprayed intensively on the moving powder and the distance between the powder and the spray nozzle is always kept constant, good coating is possible.

The ethanol solution of zein to be sprayed is preferably a solution in which 4 to 25 parts by mass of zein is dissolved with respect to 100 parts by mass of the ethanol aqueous solution. When less than 4 parts by mass of zein is used with respect to 100 parts by mass of the ethanol aqueous solution, the time for spraying the ethanol aqueous solution of zein becomes long, and the production efficiency deteriorates. On the other hand, when the amount exceeds 25 parts by mass, the viscosity of the zein aqueous ethanol solution increases, the degree of adhesion increases, and aggregation occurs between the powders, thereby forming aggregates.
When adding medium chain triglyceride, 0.1-20 mass parts of medium chain triglycerides are added with respect to 100 mass parts of ethanol aqueous solution. When 0.1 part by mass or more is added, formation of aggregates is prevented, and a zein-coated powder having a sharp particle size distribution can be obtained. On the other hand, when the amount exceeds 20 parts by mass, separation from the aqueous ethanol solution occurs, resulting in non-uniform coating.

  The ethanol aqueous solution in which zein and medium chain triglycerides are dissolved is preferably a 60 to 90% by mass ethanol aqueous solution. Here, when the ethanol concentration in the ethanol aqueous solution is less than 60% by mass, the amount of zein dissolved is low. Moreover, when it exceeds 90 mass%, a solution will gelatinize easily and is unpreferable.

  The average particle size of the zein-coated powder obtained by the step (A) is preferably 100 to 300 μm. When the thickness is less than 100 μm, when the hardened oil / fat powder collides with the zein coating, the adhesive force and the spreading force of the hardened oil / fat coating are reduced. Here, the adjustment of the average particle diameter in the step (A) is performed under the above zein coating conditions capable of suppressing granulation. Even if it is adjusted to a desired average particle size by pulverization later, the surface of the core material due to cracking of the particles will be exposed and the masking effect will be reduced, which is not preferable.

(B) Process (B) process in this invention is a process of oil-fat-coating the zein coating powder obtained at the said (A) process.
It is preferable that melting | fusing point of the hardened oil and fat powder used for this process is 50-80 degreeC. When it is less than 50 ° C., it is not preferable because it tends to be consolidated in the step of coating the zein-coated powder with the hardened fat. Moreover, when using the hardened fats and oils whose melting | fusing point exceeds 80 degreeC, the adhesive force to zein coating | coated powder falls and a coating state worsens.
Examples of the hardened oil and fat powder having a melting point of 50 to 80 ° C. include rapeseed hardened oil, hardened palm oil, hardened soybean oil, hardened high erucic acid rapeseed oil, hardened beef tallow oil, etc., and these may be used alone or in combination of two or more. Use oils and fats. Hardened fats and oils prepared by general hydrogenation are used, but hardened fats and oils having an iodine value of 3.0 or less form a more confidential crystal structure by tempering in the step (C), and mask the taste. The effect, tableting property and storage stability are increased, which is preferable. Furthermore, rapeseed hydrogenated oil, soybean hardened oil, and high erucic acid rapeseed hardened oil having an iodine value of 0.3 or less are preferable because the fatty acid composition becomes highly pure stearic acid and forms a more secret crystal structure.

  In addition, the hardened oil / fat powder used in the present invention preferably has a triacylglycerol content of 95% by mass or more. Hardened fats and oils contain impurities such as monoglycerol, diglycerol, and fatty acids, and these impurities hinder the formation of a secret crystal structure.

  The average particle diameter of the hardened oil / fat powder of the present invention is preferably 1 to 50 μm. When the average particle size is smaller than 1 μm, it is not industrially easy. When the average particle size is larger than 50 μm, it may not adhere to the surface of the zein-coated powder obtained in the step (A), and a good oil film cannot be formed. . The coating amount of the hardened oil / fat is preferably 60 to 97% by weight of the zein-coated powder obtained in the step (A) and 3 to 40% by weight of the hardened oil / fat. When the coating amount of the hardened fat is lower than 3% by mass, the taste masking effect is insufficient, and when it is higher than 40% by weight, excessive hardened fat powder adheres to the inner wall of the tank and solidifies. To do.

In the present invention, the peak intensity ratio between 2θ (19 °) and 2θ (21 °) (19 ° / 21 ° intensity ratio) in an X-ray diffraction measurement using CuKα rays as a light source is 0.6 or less. Hardened fat powder is used for coating. This peak intensity ratio (19 ° / 21 ° intensity ratio) serves as an index of the ratio of α-type crystal polymorph and β-type crystal polymorph as described above. In the present invention, the peak intensity ratio (19 ° / 21 ° A polymorphic hardened oil / fat powder rich in α-type crystal polymorphism having a 21 ° intensity ratio of 0.6 or less is used.
When the peak intensity ratio (19 ° / 21 ° intensity ratio) exceeds 0.6, it is a hard fat powder rich in β-type, which causes a decrease in adhesion to the zein film.
In addition, the hardened oil and fat powder having a peak intensity ratio (19 ° / 21 ° intensity ratio) of 0.6 or less is obtained by dissolving the hardened oil and fat with heat equal to or higher than the melting point and rapidly cooling and recrystallizing it. Etc., and can be easily obtained by pulverizing to an average particle size of 1 to 50 μm. For recrystallization of fats and oils, there are a method in which hardened fats and oils are made into a plate or flake shape and pulverized, and a method of obtaining hardened fats and oils having an average particle diameter of 1 to 50 μm without pulverizing by spray cooling.

In the present invention, the step of forming the hardened oil / fat coating is a step in which the hardened oil / fat powder collides with the zein-coated powder obtained in the step (A) and the hardened fat / oil is fixed on the entire peripheral surface of the zein-coated powder. . Examples of the high-speed stirring mixer include “Product Name: OM Dizer” manufactured by Nara Machinery Co., Ltd., and “Product Name: Vertical Granulator” manufactured by Paulek Co., Ltd.
The collision condition is a condition in which the solid hardened oil / fat powder collides with the zein-coated powder, and the powder temperature is preferably 45 ° C. or less. When it exceeds 45 degreeC, there exists a possibility that hardened fats and oils may soften and it may solidify in a tank.

Step (C) Step (C) of the present invention is a step of transferring the fat rich in α-type polymorph coated on the surface of the zein-coated powder in step (B) to the fat rich in β-type polymorph.
In the step (C) of the present invention, the oil-coated powder is tempered at 35 to 60 ° C. for 1 to 200 hours, so that the crystal polymorph of the hardened fat is transferred from the unstable α-type to the stable β-type.
When the tempering temperature is lower than 35 ° C., the transition takes a long time and the productivity is deteriorated. Moreover, when a tempering temperature exceeds 60 degreeC, the film of hardened fats and oils will melt | dissolve and the masking effect of taste will become low.
Furthermore, when the tempering temperature is 40 to 50 ° C., the tempering time can be shortened to 1 to 100 hours, and the production efficiency is increased, which is preferable. If it is 40 ° C. or higher, the solid phase transition rate will increase, but if it exceeds 50 ° C., the hardened oil / fat coating may soften depending on the melting point of the hardened oil / fat, causing problems such as solidification of the coated particles and peeling of the coating. There is.
The tempering time is preferably longer than the time required for the peak intensity ratio (19 ° / 21 ° intensity ratio) to be 2 or more.
By this step (C), the α type cannot obtain a sufficient masking effect, tableting property and storage stability, but the transition to the β type increases the masking effect, tableting property and storage stability. .

The average particle size of the coating powder obtained in the present invention is preferably 100 to 300 μm. When the average particle size is smaller than 100 μm, the taste masking effect is weak, and when it is larger than 300 μm, the tongue feel is poor.
The coated powder obtained in the present invention can be used to facilitate the taking of pharmaceuticals and health foods having a taste such as bitterness. In addition, by adding the coating powder of the present invention coated with a sour agent such as citric acid and malic acid to a gum, etc., by chewing it, the taste is gradually released and the food is maintained for a long time. Can also be applied.

  Hereinafter, although an Example and a comparative example demonstrate in detail, this invention is not limited to these.

(Measuring method of melting point and iodine number)
This was performed in accordance with the standard oil analysis method established by the Japan Oil Chemists' Society. For the melting point, the “rising melting point method” was used, and for the iodine value, the “Wiis-carbon tetrachloride method” was used.

(Purity of hardened oil and fat)
About 1 g of hardened oil and fat powder is accurately weighed, dissolved in 30 mL of chloroform, and filtered. Wash the filter paper thoroughly with chloroform and collect the liquid in which the hardened fats and oils are dissolved. The collected chloroform solution is sufficiently dried by a rotary evaporator (liquid temperature 70 ° C.), and the weight of the collected solid content is measured. The ratio (y%) of the collected solid content to the hardened oil / fat powder subjected to the test is determined. The solid content was dissolved in chloroform, and the area ratio of triacylglycerol to the total area was measured using Iatroscan “trade name; MK-5” (manufactured by Iatron) (developing solution: hexane / ether (80/20)). Is multiplied by y% to determine the purity of triacylglycerol.

(19 ° / 21 ° intensity ratio)
The X-ray diffraction measurement was performed by “trade name: RINT-Utima” manufactured by Rigaku Corporation. Tube voltage: 20 kV, tube current: 40 mA, start angle 3 °, end angle 30 °, scan speed: 2 ° / min, a sample sample was filled in a sample holder, and measurement was performed. As described above, the peak intensity of 2θ = 16 to 27 °, particularly the 19 ° / 21 ° intensity ratio can be calculated for identification of the crystal polymorph of the hardened fat.

(Average particle size)
The average particle size of the powder was measured using a laser dry particle size distribution analyzer (trade name: SALD-2100, manufactured by Shimadzu Corporation). Evaluation was performed using data-processed values by the built-in program “Wing-1”.

(Feeling of the tongue)
About 50 mg was placed on the tongue, and the evaluation was made in three stages: ○: little roughness, Δ: slightly rough, and × rough.

(Taste strength)
Put about 50mg on your tongue and swallow it after putting it in your mouth for 20 seconds. The intensity of the taste felt at this time was evaluated in five stages: 1: not felt, 2: hardly felt, 3: slightly felt, 4: felt, 5: felt strongly.

(Storage stability)
The state of the double-coated powder one month after production (room temperature storage) was visually inspected.

(Tabletability)
300 g of powder obtained by Examples and Comparative Examples, 200 g of lactose (manufactured by Asahi Kasei Chemicals Co., Ltd., trade name: SUPER TAB), and sucrose fatty acid ester (manufactured by Mitsubishi Chemical Foods Co., Ltd., trade name: Sugar Ester B- (370F) 10 g was mixed and tableted using a rotary tableting machine. A tableted product was prepared under the conditions of a tablet weight of 400 mg, a grape seed of 10 mm diameter, R = 8.5 mm, and a tableting pressure of 10,000 N. 200 tablets were randomly taken out from these tableted products and examined for the presence of sticking.

Example 1
500 g of glucosamine powder (manufactured by Yaizu Suisan Kagaku Kogyo Co., Ltd., trade name: natural glucosamine, average particle size 108 μm) is charged into a rolling fluidized bed apparatus (manufactured by Dalton Co., Ltd., trade name: Numeralizer NQ-160). A coating solution in which 58.8 g of zein (manufactured by Kobayashi Fragrance Co., Ltd., trade name: Kobayashi Zein DP) was dissolved in 530 g of hydrous ethanol (purified water / ethanol = 30/70 (v / v)) was sprayed. The operating conditions were as follows: supply air temperature: 75 ° C., supply air volume: 1 m ³ / min, rotor rotation speed: 300 rpm, spray liquid speed: 15 g / min. 503 g of zein-coated powder having an average particle size of 125 μm was obtained.
450 g of the obtained zein-coated powder and 50 g of rapeseed extremely hardened oil (melting point 67 ° C., 19 ° / 21 ° peak intensity ratio 0.35, iodine value 1.1, triacylglycerol purity 100%, average particle size 12 μm) The mixture was charged into a high-speed stirrer (trade name: VG-05, manufactured by POWREC Co., Ltd.), and mixed for 40 minutes at a blade rotation speed of 500 rpm, a cross screw rotation speed of 2000 rpm, and a jacket temperature of 25 ° C. This was put into a 45 degreeC thermostat, and left still for 5 hours, and 490g of oil-fat coating powder with an average particle diameter of 121 micrometers was obtained. About the obtained oil-and-fat coating powder, the touch, taste strength, and storage stability test were done. The test results are shown in Table 1.

Example 2
In the production method of Example 1, 53 g of zein (manufactured by Kobayashi Fragrance Co., Ltd., trade name: Kobayashi Zein DP) and medium chain triglyceride (manufactured by Nippon Oil & Fats Co., Ltd., trade name: Panacet 810) are used as the coating liquid. 9 g was dissolved in 530 g of hydrous ethanol (purified water / ethanol = 30/70 (v / v)), and the same procedure was performed.

Example 3
In the production method of Example 1, rapeseed extremely hardened oil (melting point 67 ° C., 19 ° / 21 ° peak intensity ratio 0.55, iodine number 1.1, triacylglycerol purity 100%, average particle diameter as fat coating material) 12 μm) was used in the same manner.

Example 4
In the production method of Example 1, rapeseed extremely hardened oil (melting point 62 ° C., 19 ° / 21 ° peak intensity ratio 0.31, iodine value 3.2, triacylglycerol purity 100%, average particle size as fat coating material 12 μm) was used in the same manner.

Examples 5 and 6
In the production method of Example 1, the tempering temperature and time were set to 37 ° C. for 5 hours in Example 5, and 55 ° C. for 3 hours in Example 6, and the same procedure was performed.

Example 7
L-leucine powder (manufactured by Kyowa Hakko Kogyo Co., Ltd., trade name: L-leucine, average particle size 127 μm) 500 g, zein (manufactured by Kobayashi Fragrance Co., Ltd., trade name: Kobayashi Zein DP) 115.4 g of water-containing ethanol ( It was produced in the same manner as in Example 1 using 654 g of purified water / ethanol = 30/70 (v / v)). 520 g of zein-coated powder having an average particle size of 138 μm was obtained.
400 g of the obtained zein-coated powder and 100 g of rapeseed extremely hardened oil of Example 1 were used and produced in the same manner as in Example 1.
The resulting double-coated powder was subjected to touch, taste strength, tableting test, and storage stability test. The test results are shown in Table 1.

Comparative Example 1
500 g of glucosamine powder (manufactured by Yaizu Suisan Kagaku Kogyo Co., Ltd., trade name: natural glucosamine, average particle size 108 μm) is charged into a rolling fluidized bed apparatus (manufactured by Dalton Co., Ltd., trade name: Numeralizer NQ-160). A coating solution in which 88.2 g of zein (“Kobayashi Zein DP” manufactured by Kobayashi Fragrance Co., Ltd.) was dissolved in 500 g of hydrous ethanol (purified water / ethanol = 30/70 (v / v)) was sprayed. The operating conditions were the same as in Example 1. 510 g of zein-coated powder having an average particle size of 125 μm was obtained.
The resulting zein-coated powder was tested for touch, taste strength, and storage stability. The test results are shown in Table 2.

Comparative Example 2
425 g of glucosamine powder (made by Yaizu Suisan Chemical Co., Ltd., trade name: natural glucosamine, average particle size 108 μm) and 75 g of rapeseed extremely hardened oil are added to a high-speed stirrer (trade name: VG-05, manufactured by POWREC Co., Ltd.). Preparation and mixing as in Example 1. This was put into a 45 degreeC thermostat, and left still for 12 hours, and 490g of oil-fat coating powder whose average particle diameter is 125 micrometers was obtained. About the obtained powder, the touch, taste strength, and storage stability test were done. The test results are shown in Table 2.

Comparative Example 3
In the production method of Example 1, rapeseed extremely hardened oil (melting point: 67 ° C., 19 ° / 21 ° peak intensity ratio: 2.52, iodine number: 1.2, triacylglycerol purity: 100%, average particle size as fat coating material. 12 μm) was used in the same manner.

Comparative Examples 4-6
In the manufacturing method of Example 1, the tempering temperature and time were the same as in Comparative Example 4 except that tempering treatment was not performed, Comparative Example 5 was 30 ° C. for 12 hours, and Comparative Example 6 was 70 ° C. for 3 hours.

Comparative Example 7
115.4 g of gelatin (“Nitta Gelatin GBL-200”, manufactured by Nitta Gelatin Co., Ltd.) is added to 500 g of L-leucine powder (manufactured by Kyowa Hakko Kogyo Co., Ltd., trade name: L-leucine, average particle size 127 μm). A coating solution dissolved in 2000 g of purified water was sprayed. The operating conditions were as follows: supply air temperature: 85 ° C., supply air volume: 1 m 3 / min, rotor rotation speed: 300 rpm, spray liquid speed: 12 g / min. 508 g of zein-coated powder having an average particle size of 238 μm was obtained.
Using the obtained gelatin-coated powder 400 g and the rapeseed extremely hardened oil 100 g of Example 1, it was produced in the same manner as in Example 1. However, the tempering process was not performed.
About the obtained oil-and-fat coating powder, the touch, taste strength, tableting test, and storage stability test were performed. The test results are shown in Table 2.

Comparative Example 8
An oil-coated powder was prepared in the same manner as in Comparative Example 7 and tempered at 45 ° C. for 5 hours.

Comparative Example 9
Example: 500 g of glucosamine powder (manufactured by Yaizu Suisan Kagaku Kogyo Co., Ltd., trade name: natural glucosamine, average particle size 108 μm) was charged into a fluidized bed granulator (manufactured by Freund Sangyo Co., Ltd., trade name: Flow Coater Mini). The zein solution was sprayed in the same manner as in 1. The spray used the top spray type. The operating conditions were an air supply temperature: 75 ° C., an air supply amount: 1 m ³ / min, and a spray liquid speed: 30 g / min, and 490 g of granulated zein-coated powder having an average particle size of 399 μm was obtained. Using this, cured oil and fat coating and tempering treatment were performed in the same manner as in Example 1.

  From Examples 1 and 2 and Comparative Examples 1 and 2, it can be seen that the coating powder of zein and hardened oil has a high taste masking effect. From the comparative example 3, when the hardened oil and fat powder whose crystal polymorph is β type is used, the taste masking effect is weak. In Comparative Examples 4 to 7, it can be seen that the taste masking effect, storage stability, and tableting properties are low unless an appropriate tempering treatment is performed in Step C. Comparing Comparative Example 8 and Example 7, it can be seen that by using zein, a good hardened oil / fat film is formed, and the taste masking effect, tableting property, and storage stability are improved. Further, it can be seen from Comparative Example 9 that when granulated and the average particle size exceeds 300 μm, the touch of the tongue is deteriorated.

Claims (2)

The manufacturing method of the fat-and-oil coating powder containing the following (A)-(C) process and containing a taste component.
(A) The process of coat | covering zein on the powder containing a taste component.
(B) The zein-coated powder obtained in the step (A) has an average particle diameter of 1 to 50 μm, a melting point of 50 to 80 ° C., and 2θ (19 °) in X-ray diffraction measurement using CuKα rays as a light source. Hardened oil and fat powder having a peak intensity ratio (19 ° / 21 ° intensity ratio) of peak intensity and 2θ (21 °) of 0.6 or less is collided under a condition that the powder temperature is 45 ° C. or less. Obtaining step.
(C) A step of tempering the coating powder obtained in the step (B) at 35 to 60 ° C. for 1 hour to 200 hours.   An oil-coated powder having an average particle size of 100 to 300 µm obtained by the production method of claim 1.