JP2009063449A - Dispensation method, sample dispensation method of automatic analyzer, and automatic analyzer - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a dispensation method, a sample dispensation method of an automatic analyzer, and the automatic analyzer, capable of preventing contamination between liquids when moving a dispensing nozzle. <P>SOLUTION: When the dispensing nozzle is moved to a discharge position where liquid is to be discharged with the sucked liquid which is a dispensation object, the nozzle tip passes through a lower position than each upper end of a plurality of liquid containers, between the plurality of liquid containers arranged side by side with each upper end positioned approximately in the agreeing state in a closed domain, for storing the liquid respectively. <P>COPYRIGHT: (C)2009,JPO&INPIT

Description

  The present invention relates to a dispensing method for dispensing a liquid, a sample dispensing method for an automatic analyzer that analyzes a component of a sample by reacting a sample with a reagent and optically measuring the result of the reaction, and an automatic The present invention relates to an analyzer.

  Conventionally, in an automatic analyzer that analyzes a sample component by reacting a sample with a reagent and optically measuring the result of this reaction, the liquid attached to the nozzle for dispensing the liquid of the sample, reagent, etc. Various techniques have been disclosed for preventing contamination by falling in a liquid container containing the liquid.

  For example, in Patent Document 1 below, after a sample suction operation, a small amount of sample liquid is discharged to the tip of the nozzle, the nozzle is moved up and down at a predetermined speed at the discharge position, and a small amount of droplets attached to the nozzle is discharged. A technique for dropping and removing together with the sample liquid is disclosed.

  Patent Document 2 below discloses a technique for suppressing the scattering of the reagent when the nozzle is stopped by providing a vibration limiting mechanism in the nozzle holding portion.

  Furthermore, Patent Document 3 below discloses a technique for preventing contamination by reliably sucking and discharging a sample using an articulated robot arm.

JP-A-9-184846 JP 2006-84368 A JP-A-2005-181135

  However, in the above-described prior art, when the nozzle moves to the discharge position while sucking the liquid, the liquid may drop from the tip of the nozzle in the middle of the movement path and may be scattered to the liquid container located below. There was a risk of contamination between liquids.

  The present invention has been made in view of the above, and a dispensing method capable of preventing the occurrence of contamination between liquids when moving a dispensing nozzle, and sample dispensing of an automatic analyzer. It is an object to provide a method and an automatic analyzer.

  In order to solve the above-described problems and achieve the object, the dispensing method according to the present invention is arranged in a closed region in a state in which the positions of the upper ends are substantially coincided with each other, and each of a plurality of liquid containers each containing a liquid. This is a dispensing method in which a liquid to be dispensed is sucked from one of them through a nozzle for dispensing, and the sucked liquid to be dispensed is discharged from the nozzle at a discharge position located outside the closed region. When the nozzle sucks the liquid to be dispensed and moves to the discharge position, the tip of the nozzle is between the plurality of liquid containers and lower than the upper ends of the plurality of liquid containers It is characterized by passing through a position.

  The sample dispensing method of the automatic analyzer according to the present invention is the automatic analyzer that analyzes the components of the sample by reacting the sample with the reagent and optically measuring the result of the reaction. The sample to be dispensed is sucked from one of a plurality of sample containers that hold the samples in a substantially identical state and accommodates each sample through a sample nozzle for sample dispensing, and this sucked sample to be dispensed A sample dispensing method of an automatic analyzer that discharges from the sample nozzle at a predetermined sample discharge position, wherein the sample nozzle sucks the sample to be dispensed and then moves to the sample discharge position. The tip of the sample nozzle is between the plurality of sample containers and passes through a position lower than the upper ends of the plurality of sample containers.

  An automatic analyzer according to the present invention is an automatic analyzer that analyzes a component of a sample by reacting a sample with a reagent and optically measuring a result of the reaction, and each of the plurality of samples each containing a sample. A sample container holder that holds the sample containers side by side with their upper end positions substantially coincided with each other, and a sample nozzle for sample dispensing. By using the sample nozzle, the sample to be dispensed is sucked and this suction is performed. A sample dispensing means for discharging the sample to be dispensed from the sample nozzle at a predetermined sample ejection position, and when the sample nozzle moves to the sample ejection position after sucking the sample to be dispensed, Control means for performing control to pass the tip of the sample nozzle between the plurality of sample containers and lower than the upper ends of the plurality of sample containers.

  Further, the automatic analyzer according to the present invention is the above-described invention, wherein in the above-described invention, a reagent container holder for holding a plurality of reagent containers respectively storing reagents in a state in which the positions of the upper ends are substantially aligned, and a reagent nozzle for reagent dispensing A reagent dispensing means for aspirating a reagent to be dispensed by using the reagent nozzle, and discharging the aspirated reagent to be dispensed from the reagent nozzle at a predetermined reagent ejection position, The control means, when the reagent nozzle moves to the reagent discharge position after aspirating the reagent to be dispensed, the tip of the reagent nozzle is between the plurality of reagent containers, and Control that passes through a position lower than the upper end of the reagent container is performed.

  According to the present invention, when the dispensing nozzle that sucks the liquid to be dispensed from the liquid container is moved to the predetermined discharge position, the tip of the nozzle is between the plurality of liquid containers, and Since the liquid passes through a position lower than the upper end of the liquid container, even if the liquid falls from the tip of the nozzle, the dropped liquid does not scatter and enter the liquid container. Therefore, it is possible to prevent contamination between liquids when the dispensing nozzle is moved.

  The best mode for carrying out the present invention (hereinafter referred to as “embodiment”) will be described below with reference to the accompanying drawings. Note that the drawings referred to in the following description are merely schematic, and when the same object is shown in different drawings, dimensions, scales, and the like may be different.

(Embodiment 1)
FIG. 1 is a schematic diagram showing a configuration of a main part of an automatic analyzer according to Embodiment 1 of the present invention. The automatic analyzer 1 shown in FIG. 1 dispenses a sample (specimen) such as blood or body fluid and a reagent according to the inspection item of the sample into predetermined reaction containers, respectively, and converts the reaction liquid in the reaction container. A measurement unit 101 that performs optical measurement, and a data processing unit 201 that controls the automatic analyzer 1 including the measurement unit 101 and analyzes a measurement result in the measurement unit 101, and these two units Is a device that automatically and continuously performs biochemical analysis of a plurality of samples through cooperation. The “liquid” here includes a liquid containing a small amount of a solid component.

  The measurement unit 101 includes a sample container holder 11 that holds a plurality of sample containers 31 that contain samples, a reagent container holder 12 that holds a plurality of reagent containers 33 that contain reagents, and a reaction container that reacts a sample and a reagent. Reaction container holder 13 holding 34, sample dispensing section 14 for dispensing a sample contained in sample container 31 held by sample container holder 11 into reaction container 34, and reagent container 33 on reagent container holder 12. The reagent dispensing unit 15 that dispenses the contained reagent into the reaction vessel 34, the stirring unit 16 that stirs the liquid inside the reaction vessel 34, and the reaction vessel 34 are irradiated with light, and the reaction out of the irradiated light A photometric unit 17 for optically measuring light transmitted through the vessel 34, a reaction vessel washing unit 18 for washing the reaction vessel 34 on the reaction vessel holder 13 using a washing liquid made of ion-exchanged water, etc., and a sample A sample nozzle cleaning unit 19 for cleaning the sample nozzle 14n for sample dispensing included in the injection unit 14 and a reagent nozzle cleaning unit 20 for cleaning the reagent nozzle 15n for reagent dispensing included in the reagent dispensing unit 15 are provided. .

  The sample container holder 11 holds a plurality of racks 32 that hold a plurality of sample containers 31 arranged in a line along the longitudinal direction along the short direction of the rack 32 perpendicular to the longitudinal direction.

  The reagent container holder 12 and the reaction container holder 13 hold a plurality of reagent containers 33 and reaction containers 34 respectively along the circumferential direction. The interior of the reagent container holder 12 is set to a temperature lower than room temperature in order to suppress reagent deterioration and denaturation. Moreover, the inside of the reaction vessel holder 13 is set to a temperature comparable to the human body temperature. When performing a biochemical analysis, since two types of reagents are often used for one sample, the reagent container holder 12 for the first reagent and the reagent container holder 12 for the second reagent May be provided separately, and a reagent dispensing section 15 corresponding to each reagent container holder 12 may be provided separately.

  FIG. 2 is a diagram schematically illustrating the configuration of the sample dispensing unit 14. The sample dispensing unit 14 has a hollow tube and a sample nozzle 14n for sample dispensing that sucks and discharges the sample Sp accommodated in the sample container 31, and a first arm 401 to which the sample nozzle 14n is attached at the tip. And a second arm 402 connected to the proximal end side of the first arm 401, a joint portion that connects the first arm 401 and the second arm 402, and rotates the first arm 401 relative to the second arm 402. 403, a support portion 404 that supports the base end portion of the second arm 402, and an arm drive that rotates the first arm 401 relative to the second arm 402 by rotating about the axis O1 of the joint portion 403. And an arm driving unit 406 that rotationally drives the second arm 402 by moving the support unit 404 up and down and rotating around the axis O2. The arm driving units 405 and 406 are driven under the control of the control unit 24 included in the data processing unit 201.

  Since the sample dispensing unit 14 includes two arms, the length of the arm from the support unit 404 to the sample nozzle 14n can be changed. For this reason, the sample dispensing unit 14 adjusts the length of the arm from the support unit 404 to the sample nozzle 14n, thereby causing the sample nozzle 14n to reach all the sample containers 31 held by the sample container holder 11. be able to. In addition, the sample nozzle 14n can be made to reach the sample nozzle cleaning unit 19 located away from the sample container holder 11.

  Connected to the upper end of the sample nozzle 14n is a tubular tube 407 serving as a flow path for the cleaning liquid Lq that transmits pressure to the lower end (tip) of the sample nozzle 14n during suction or discharge. The other end of the tube 407 is connected to a syringe 408 that generates a pressure to be transmitted through the cleaning liquid Lq during suction or discharge. The syringe 408 includes a cylinder 408a and a piston 408b, and the piston 408b is moved by driving the piston driving unit 409. The syringe 408 is also connected to a tube 410 that is different from the tube 407. An electromagnetic valve 411 is connected to the other end of the tube 410. The electromagnetic valve 411 is connected to a pump 413 through a tube 412, and the pump 413 is connected to a cleaning liquid tank 415 that stores the cleaning liquid Lq through a tube 414. The piston drive unit 409, the electromagnetic valve 411, and the pump 413 are driven under the control of the control unit 24 included in the data processing unit 201.

  Each of the sample nozzle 14n, cylinder 408a, tubes 407, 410, 412 and 414 is filled with the cleaning liquid Lq, and when the sample Sp is sucked or discharged, the piston drive unit 409 is driven and the piston is driven. By moving 408b, an appropriate suction pressure or discharge pressure is applied to the tip of the sample nozzle 14n via the cleaning liquid Lq. Since an air layer is interposed between the cleaning liquid Lq and the sample Sp at the lower end of the sample nozzle 14n, the sample Sp is not mixed with the cleaning liquid Lq when the sample Sp is sucked.

  In addition, it is also possible to provide a liquid level detection mechanism for detecting the liquid level at the lower end of the sample nozzle 14n for the sample dispensing unit 14.

  The reagent dispensing unit 15 includes a reagent nozzle 15n, an arm 501 that moves while supporting the reagent nozzle 15n, and a suction / discharge mechanism and a liquid level detection mechanism (not shown). The reagent dispensing unit 15 has the same configuration as the sample dispensing unit 14 described above except that the reagent dispensing unit 15 is configured using one arm 501.

  The photometry unit 17 receives, for each component, a light source 17a that emits white light, a spectroscopic optical system 17b that splits white light that has passed through the reaction vessel 34, and light that is spectrally separated by the spectroscopic optical system 17b. A light receiving element 17c for conversion.

  By the way, in FIG. 1, since the main purpose is to schematically show the main components of the measurement unit 101, the positional relationship between the components is not always accurate. The exact positional relationship between the components of the measurement unit 101 is determined according to various conditions such as the number of reagent container holders 12 and the rotation mode of the reaction container holder 13 during the dispensing operation interval.

  Next, the configuration of the data processing unit 201 will be described. The data processing unit 201 is realized by a computer having a CPU, a ROM, a RAM, and the like. The data processing unit 201 includes a keyboard, a mouse, and the like. The data processing unit 201 receives an input of information necessary for analyzing a sample, information including an operation instruction signal of the automatic analyzer 1, a display device such as a liquid crystal display, An output unit 22 that has a printer and outputs information relating to sample analysis, a data generation unit 23 that generates sample analysis data based on the measurement results in the measurement unit 101, and a control that controls the automatic analyzer 1. And a storage unit 25 that stores various types of information including calculation results based on the measurement results of the measurement unit 101.

  The data generation unit 23 performs an analysis operation on the measurement result received from the photometry unit 17 of the measurement unit 101. In this analytical calculation, the absorbance of the liquid inside the reaction vessel 34 is calculated based on the measurement result sent from the photometry unit 17, or the absorbance calculation result and various information such as a calibration curve and analysis parameters are used. Analytical data for each sample is generated by quantitatively determining the liquid components in the reaction vessel 34.

  The storage unit 25 includes analysis items, sample information, reagent types, sample and reagent dispensing amounts, sample and reagent expiration dates, information on calibration curves used for analysis, calibration curve expiration dates, and reference to each analysis item Parameters necessary for analysis such as values and allowable values, analysis data generated by the data generation unit 23, and the like are stored.

  3-5 is a figure which shows the outline | summary of the sample dispensing method in which the sample dispensing part 14 dispenses sample Sp in the automatic analyzer 1 which has the above structure. The sample dispensing unit 14 raises the first arm 401 and the second arm 402 by raising the support unit 404 after sucking the sample Sp stored in the sample container 31 at the position A shown in FIG. Thereafter, as shown in FIG. 4, the sample dispensing unit 14 places the sample in the gap W between the rack 32 on which the sample container 31 at the position A is mounted and the rack 32 adjacent to the left side of the rack 32. The nozzle 14n is moved.

  FIG. 4 shows a case where the sample nozzle 14n is moved to the gap W by rotating the second arm 402 without changing the angle formed by the first arm 401 and the second arm 402. It is also possible to move to the gap W between the racks 32 by moving in the horizontal direction in FIG. In this case, the angle between the first arm 401 and the second arm 402 also changes according to the position of the sample nozzle 14n.

  When the sample nozzle 14n that has sucked the sample at the position A is moved, the sample nozzle 14n may be moved to the gap W 'between the adjacent rack 32 on the right side of the suction position A.

  Subsequently, the sample dispensing unit 14 moves the sample nozzle 14n so that the tip of the sample nozzle 14n passes through the gap W between the two racks 32, as shown in FIG. At this time, since the tip of the sample nozzle 14n moves linearly, the movement of the sample nozzle 14n is realized by performing both the rotation of the first arm 401 and the rotation of the second arm 402.

  FIG. 6 is a diagram showing the relationship between the tip position of the sample nozzle 14n and the upper end position of the sample container 31 when moving the sample nozzle 14n. In FIG. 6, the tip of the sample nozzle 14 n passes through a position lower than the upper end of the sample container 31 by h. The value of h is about several mm.

  The sample nozzle 14n that has passed through the gap W as described above moves to the sample discharge position P. At this time, as shown in FIG. 5, only the first arm 401 may be rotationally driven, or the second arm 402 is also rotationally driven so that the sample nozzle 14 n moves linearly to the reaction vessel 34. You may make it do.

  According to the first embodiment of the present invention described above, when the sample nozzle that sucks the sample to be dispensed is moved to a predetermined discharge position, the tip of the sample nozzle is between a plurality of sample containers, In addition, since the sample passes through a position lower than the upper ends of the plurality of sample containers, even if the sample falls from the tip of the sample nozzle, the dropped sample does not scatter and enter the sample container. Accordingly, it is possible to reliably prevent contamination between samples when the sample nozzle is moved.

  Further, according to the first embodiment, even in the case of an automatic analyzer equipped with a sample container holder in which a rack is fixedly arranged, the sample nozzle can be moved so as not to pass above the sample container. it can. Therefore, it is not necessary to provide a cover for preventing scattering above the sample container holder, and the number of parts can be reduced and the configuration can be simplified.

(Embodiment 2)
FIG. 7 is a diagram showing a configuration of a main part of the measurement unit and an outline of a dispensing method of the automatic analyzer according to the second embodiment of the present invention. In the measurement unit 102 of the automatic analyzer 2 shown in the figure, racks 35 for storing sample containers 31 in a line are arranged radially along a circumference concentric with a circle formed by the surface of the reaction container holder 13. .

  The sample dispensing unit 61 can rotate about the center of the reaction vessel holder 13 as a rotation center, and can extend and contract in the radial direction of the reaction vessel holder 13 from the third arm 611 having a constant length and the tip of the third arm 611. And a fourth arm 612 to which the sample nozzle 61n is attached at the tip. Among the radial directions of the circle formed by the reaction container holder 13, the radial direction L passing through the sample discharge position P forms a movement path when the fourth arm 612 contracts and the sample nozzle 61n reaches the sample discharge position P. Therefore, it is desirable that the rack 35 is not disposed as shown in FIG.

  In FIG. 7, the sample dispensing unit 61 sucks the sample Sp accommodated in the sample container 31 at the position B by the sample nozzle 61n, and then contracts the fourth arm 612 to mount the sample container 31 at the position B. The sample nozzle 61n is moved to an annular gap W2 between the rack 35 and the rack 35 adjacent to the rack 35 on the inner peripheral side. Thereafter, the sample dispensing unit 61 rotates the third arm 611 without changing the length of the fourth arm 612 until the sample nozzle 61n reaches the radial direction L of the sample discharge position P. Thereby, the sample nozzle 61n moves in the gap W2. When the sample nozzle 61n reaches a point C that intersects the radial direction L of the sample discharge position P, the sample dispensing unit 61 further contracts the fourth arm 612 and moves the sample nozzle 61n to the sample discharge position P.

  Also in the second embodiment, when the sample nozzle 61n moves through the gap W2, the tip of the sample nozzle 61n passes through a position lower than the upper end of the surrounding sample container 31.

  A sample nozzle cleaning unit 62 for cleaning the sample nozzle 61n is provided at a position where the sample nozzle 61n can reach.

  According to the second embodiment of the present invention described above, when the sample nozzle that sucks the sample to be dispensed is moved to a predetermined discharge position, the tip of the sample nozzle is between a plurality of sample containers, In addition, since the sample passes through a position lower than the upper ends of the plurality of sample containers, even if the sample falls from the tip of the sample nozzle, the dropped sample does not scatter and enter the sample container. Accordingly, it is possible to reliably prevent contamination between samples when the sample nozzle is moved.

(Embodiment 3)
FIG. 8 is a diagram showing the configuration and operation of the main part of the measurement unit of the automatic analyzer according to Embodiment 3 of the present invention. The sample dispensing unit 71 of the measurement unit 103 of the automatic analyzer 3 shown in FIG. 3 moves the sample nozzle 71n, the arm 711 equipped with the sample nozzle 71n, and the arm 711 linearly in each of the three-dimensional directions. A dimension stage (not shown). The configuration of the automatic analyzer 3 excluding this point is the same as that of the automatic analyzer 1 according to the first embodiment.

  The sample dispensing unit 71 sucks the sample Sp stored in the sample container 31 at the position D shown in FIG. 8 and then adjoins the rack 32 on which the sample container 31 at the position D is mounted and the left side of the rack 32. The sample nozzle 71n is moved to the gap W3 with the rack 32 to be moved. Thereafter, after the sample nozzle 71n moves linearly along the gap W3 and reaches a position where it can move linearly to the sample discharge position P, the three-dimensional stage changes the moving direction of the arm 711, and the sample discharge position The sample nozzle 71n is moved to P. During this movement, the tip of the sample nozzle 71n passes through a position lower than the upper end of the sample container 31 held by the rack 32.

  A sample nozzle cleaning unit 72 for cleaning the sample nozzle 71n is provided at a position where the sample nozzle 71n can reach.

  According to the third embodiment of the present invention described above, as in the two embodiments described above, it is possible to reliably prevent contamination between samples when the sample nozzle is moved.

(Other embodiments)
So far, the first to third embodiments have been described in detail as the best mode for carrying out the present invention, but the present invention should not be limited by these embodiments. For example, the present invention can also be applied to a reagent dispensing unit that dispenses a reagent. In this case, a reagent dispensing unit having the same configuration as any of the sample dispensing units described above can be applied.

  In addition, the automatic analyzer according to the present invention can be applied not only to biochemical analysis of a sample but also to immunological analysis of a sample or genetic analysis of a sample. it can.

  Furthermore, the dispensing method according to the present invention is not limited to an automatic analyzer and can be applied.

  As described above, the present invention can include various embodiments and the like not described herein, and various design changes and the like can be made without departing from the technical idea specified by the claims. It is possible to apply.

It is a figure which shows the structure of the main part of the automatic analyzer which concerns on Embodiment 1 of this invention. It is a figure which shows the structure of a sample dispensing part. It is a figure which shows the state which has attracted | sucked the sample. It is a figure which shows the state which moved the nozzle between racks after attracting | sucking a sample. It is a figure which shows the movement path | route at the time of moving a nozzle to a sample discharge position. It is a figure which shows the relationship between the front-end | tip position of a nozzle at the time of moving a nozzle, and the upper end position of a sample container. It is a figure which shows the structure of the automatic analyzer principal part which concerns on Embodiment 2 of this invention, and the movement path | route of a nozzle. It is a figure which shows the structure of the main part of an automatic analyzer which concerns on Embodiment 3 of this invention, and the movement path | route of a nozzle.

Explanation of symbols

1, 2, 3 Automatic analyzer 11 Sample container holder 12 Reagent container holder 13 Reaction container holder 14, 61, 71 Sample dispensing unit 14n, 61n, 71n Sample nozzle 15 Reagent dispensing unit 15n Reagent nozzle 16 Stirring unit 17 Photometric unit 17a light source 17b spectroscopic optical system 17c light receiving element 18 reaction vessel cleaning unit 19, 62, 72 sample nozzle cleaning unit 20 reagent nozzle cleaning unit 21 input unit 22 output unit 23 data generation unit 24 control unit 25 storage unit 31 sample container 32, 35 Rack 33 Reagent container 34 Reaction container 101, 102, 103 Measurement unit 201 Data processing unit 401 First arm 402 Second arm 403 Joint part 404 Support part 405, 406 Arm drive part 407, 410, 412, 414 Tube 408 Syringe 408a Cylinder 408b Stone 409 piston driving unit 411 solenoid valve 413 the pump 415 Solution tank 501,711 arm 611 third arm 612 fourth arm

Claims (4)

The liquid to be dispensed is aspirated from one of a plurality of liquid containers each containing a liquid via a dispensing nozzle, and the aspirated liquid is aspirated. A dispensing method for discharging a liquid to be dispensed from the nozzle at a discharge position located outside the closed region,
When the nozzle sucks the liquid to be dispensed and moves to the discharge position, the tip of the nozzle is positioned between the plurality of liquid containers and lower than the upper ends of the plurality of liquid containers. Dispensing method characterized by passing. In an automatic analyzer that analyzes the components of the sample by reacting the sample with the reagent and optically measuring the results of the reaction, the samples are held side by side with their upper end positions approximately coincident. Automatically sucking a sample to be dispensed from one of a plurality of sample containers through a sample nozzle for sample dispensing, and discharging the sucked sample to be dispensed from the sample nozzle at a predetermined sample discharge position A sample dispensing method for an analyzer,
When the sample nozzle sucks the sample to be dispensed and moves to the sample discharge position, the tip of the sample nozzle is between the plurality of sample containers and from the upper ends of the plurality of sample containers A sample dispensing method for an automatic analyzer characterized by passing through a low position. An automatic analyzer that analyzes a component of the sample by reacting the sample with a reagent and optically measuring the result of the reaction,
A sample container holder for holding and holding a plurality of sample containers each containing a sample in a state in which the positions of the upper ends are substantially coincided with each other;
A sample dispenser having a sample nozzle for dispensing a sample, sucking a sample to be dispensed by using the sample nozzle, and discharging the sucked sample to be dispensed from the sample nozzle at a predetermined sample discharge position Ordering means;
When the sample nozzle sucks the sample to be dispensed and moves to the sample discharge position, the tip of the sample nozzle is between the plurality of sample containers and from the upper ends of the plurality of sample containers Control means for performing control through a low position;
An automatic analyzer characterized by comprising: A reagent container holder for holding a plurality of reagent containers, each containing a reagent, arranged side by side in a state in which the positions of the upper ends thereof substantially coincide with each other;
A reagent dispenser having a reagent nozzle for dispensing a reagent, sucking a reagent to be dispensed by using the reagent nozzle, and discharging the aspirated reagent to be dispensed from the reagent nozzle at a predetermined reagent discharge position Ordering means;
With
The control means includes
When the reagent nozzle moves to the reagent discharge position after aspirating the reagent to be dispensed, the tip of the reagent nozzle is between the plurality of reagent containers and from the upper ends of the plurality of reagent containers 4. The automatic analyzer according to claim 3, wherein control is performed to pass through a low position.

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