JP2008540650A5 - - Google Patents
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- Publication number
- JP2008540650A5 JP2008540650A5 JP2008512351A JP2008512351A JP2008540650A5 JP 2008540650 A5 JP2008540650 A5 JP 2008540650A5 JP 2008512351 A JP2008512351 A JP 2008512351A JP 2008512351 A JP2008512351 A JP 2008512351A JP 2008540650 A5 JP2008540650 A5 JP 2008540650A5
- Authority
- JP
- Japan
- Prior art keywords
- enantiomeric excess
- derivative
- selective
- further step
- nanchio
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000007062 hydrolysis Effects 0.000 claims description 2
- 238000006460 hydrolysis reaction Methods 0.000 claims description 2
- 230000002210 biocatalytic effect Effects 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 238000002425 crystallisation Methods 0.000 description 2
- 230000008025 crystallization Effects 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 239000011942 biocatalyst Substances 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68315005P | 2005-05-20 | 2005-05-20 | |
| US60/683,150 | 2005-05-20 | ||
| PCT/US2006/017978 WO2006127273A2 (en) | 2005-05-20 | 2006-05-09 | Asymmetric hydrogenation for the preparation of diphenylalanine derivatives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008540650A JP2008540650A (ja) | 2008-11-20 |
| JP2008540650A5 true JP2008540650A5 (enExample) | 2012-05-31 |
| JP5001263B2 JP5001263B2 (ja) | 2012-08-15 |
Family
ID=37027602
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008512351A Expired - Fee Related JP5001263B2 (ja) | 2005-05-20 | 2006-05-09 | ジフェニルアラニン誘導体作製のための不斉水素化 |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1885688B1 (enExample) |
| JP (1) | JP5001263B2 (enExample) |
| CN (1) | CN101175715B (enExample) |
| AT (1) | ATE482182T1 (enExample) |
| DE (1) | DE602006017064D1 (enExample) |
| WO (1) | WO2006127273A2 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8680278B2 (en) * | 2007-10-30 | 2014-03-25 | Janssen Pharmaceutica Nv | Enantioselective process for preparing a substituted alkanoic acid |
| JP2023535595A (ja) * | 2020-07-28 | 2023-08-18 | ジャズ ファーマシューティカルズ アイルランド リミテッド | 縮合二環式ｒａｆ阻害剤のキラル合成 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5198548A (en) * | 1992-01-30 | 1993-03-30 | Warner-Lambert Company | Process for the preparation of D(-) and L(+)-3,3-diphenylalanine and D(-) and L(+)-substituted 3,3-diphenylalanines and derivatives thereof |
| US5874629A (en) * | 1996-06-12 | 1999-02-23 | Merck & Co., Inc. | Chiral bisphosphines |
| WO2002057278A1 (en) * | 2001-01-19 | 2002-07-25 | Chirotech Technology Limited | Ligands and their use |
| JP2007537256A (ja) * | 2004-05-11 | 2007-12-20 | メルク エンド カムパニー インコーポレーテッド | Ｎ−スルホン化アミノ酸誘導体調製のためのプロセス |
-
2006
- 2006-05-09 EP EP06770147A patent/EP1885688B1/en not_active Not-in-force
- 2006-05-09 AT AT06770147T patent/ATE482182T1/de not_active IP Right Cessation
- 2006-05-09 WO PCT/US2006/017978 patent/WO2006127273A2/en not_active Ceased
- 2006-05-09 DE DE602006017064T patent/DE602006017064D1/de active Active
- 2006-05-09 CN CN2006800170720A patent/CN101175715B/zh not_active Expired - Fee Related
- 2006-05-09 JP JP2008512351A patent/JP5001263B2/ja not_active Expired - Fee Related