JP2008539184A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2008539184A5 JP2008539184A5 JP2008508156A JP2008508156A JP2008539184A5 JP 2008539184 A5 JP2008539184 A5 JP 2008539184A5 JP 2008508156 A JP2008508156 A JP 2008508156A JP 2008508156 A JP2008508156 A JP 2008508156A JP 2008539184 A5 JP2008539184 A5 JP 2008539184A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- immunogenic fragment
- fragment
- vaccine
- immunogenic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000012634 fragment Substances 0.000 claims 35
- 230000002163 immunogen Effects 0.000 claims 27
- 108090000623 proteins and genes Proteins 0.000 claims 24
- 102000004169 proteins and genes Human genes 0.000 claims 24
- 229960005486 vaccine Drugs 0.000 claims 19
- 239000003814 drug Substances 0.000 claims 9
- 230000028993 immune response Effects 0.000 claims 9
- 238000004519 manufacturing process Methods 0.000 claims 9
- 239000000203 mixture Substances 0.000 claims 8
- 241000341655 Human papillomavirus type 16 Species 0.000 claims 7
- 108700005307 Human papillomavirus HPV L1 Proteins 0.000 claims 6
- 239000002671 adjuvant Substances 0.000 claims 6
- 208000022361 Human papillomavirus infectious disease Diseases 0.000 claims 4
- 101000641175 Human papillomavirus type 18 Major capsid protein L1 Proteins 0.000 claims 4
- 101100209954 Human papillomavirus type 16 L1 gene Proteins 0.000 claims 3
- 230000003612 virological effect Effects 0.000 claims 3
- 241000701806 Human papillomavirus Species 0.000 claims 2
- AZDRQVAHHNSJOQ-UHFFFAOYSA-N alumane Chemical class [AlH3] AZDRQVAHHNSJOQ-UHFFFAOYSA-N 0.000 claims 2
- 108700042300 human papillomavirus type 52 L1 Proteins 0.000 claims 2
- 239000007764 o/w emulsion Substances 0.000 claims 2
- 208000009608 Papillomavirus Infections Diseases 0.000 claims 1
- 229930182558 Sterol Natural products 0.000 claims 1
- 230000007123 defense Effects 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000003995 emulsifying agent Substances 0.000 claims 1
- 231100000590 oncogenic Toxicity 0.000 claims 1
- 230000002246 oncogenic effect Effects 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 150000003432 sterols Chemical class 0.000 claims 1
- 235000003702 sterols Nutrition 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US67482905P | 2005-04-26 | 2005-04-26 | |
| GB0509010A GB0509010D0 (en) | 2005-05-03 | 2005-05-03 | Vaccine |
| PCT/EP2005/006461 WO2005123125A1 (en) | 2004-06-16 | 2005-06-14 | Vaccine against hpv16 and hpv18 and at least another hpv type selected from hpv 31, 45 or 52 |
| PCT/EP2006/003918 WO2006114312A2 (en) | 2005-04-26 | 2006-04-24 | Vaccine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008539184A JP2008539184A (ja) | 2008-11-13 |
| JP2008539184A5 true JP2008539184A5 (https=) | 2009-04-23 |
Family
ID=36992675
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008508156A Pending JP2008539184A (ja) | 2005-04-26 | 2006-04-24 | ワクチン |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20090181052A1 (https=) |
| EP (1) | EP1877086A2 (https=) |
| JP (1) | JP2008539184A (https=) |
| KR (1) | KR20080005585A (https=) |
| AR (1) | AR054259A1 (https=) |
| AU (1) | AU2006239422A1 (https=) |
| CA (1) | CA2606092A1 (https=) |
| EA (1) | EA013326B1 (https=) |
| MX (1) | MX2007013472A (https=) |
| NO (1) | NO20075194L (https=) |
| SG (1) | SG159525A1 (https=) |
| WO (1) | WO2006114312A2 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI457133B (zh) | 2005-12-13 | 2014-10-21 | Glaxosmithkline Biolog Sa | 新穎組合物 |
| BRPI0916732B1 (pt) * | 2008-07-31 | 2021-06-29 | Glaxosmithkline Biologicals S.A. | Vacina para a prevenção de doença ou infecção relacionada ao papilomavirus humano (hpv) compreendendo partículas semelhantes ao vírus hpv 16 e hpv 18 |
| US9566323B2 (en) * | 2009-06-19 | 2017-02-14 | Eyegene Inc. | Vaccine for cervical cancer |
| US20140127260A1 (en) | 2011-06-24 | 2014-05-08 | Ramesh V. Chintala | Hpv vaccine formulations comprising aluminum adjuvant and methods of producing same |
| WO2021163002A1 (en) | 2020-02-14 | 2021-08-19 | Merck Sharp & Dohme Corp. | Hpv vaccine |
| EP4380615A1 (en) | 2021-08-06 | 2024-06-12 | Merck Sharp & Dohme LLC | Hpv vaccine |
| EP4387660A1 (en) | 2021-08-19 | 2024-06-26 | Merck Sharp & Dohme LLC | Thermostable lipid nanoparticle and methods of use thereof |
| WO2024254226A1 (en) | 2023-06-09 | 2024-12-12 | Merck Sharp & Dohme Llc | Nanoemulsion adjuvant compositions for human papillomavirus vaccines |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9921146D0 (en) * | 1999-09-07 | 1999-11-10 | Smithkline Beecham Biolog | Novel composition |
| GB9921147D0 (en) * | 1999-09-07 | 1999-11-10 | Smithkline Beecham Biolog | Novel composition |
| US6908613B2 (en) * | 2000-06-21 | 2005-06-21 | Medimmune, Inc. | Chimeric human papillomavirus (HPV) L1 molecules and uses therefor |
| GB0105606D0 (en) * | 2001-03-07 | 2001-04-25 | Cantab Pharmaceuticals Res Ltd | Immunogens and vaccines and their preparation and use |
| GB0206360D0 (en) * | 2002-03-18 | 2002-05-01 | Glaxosmithkline Biolog Sa | Viral antigens |
| WO2004056389A1 (en) * | 2002-12-20 | 2004-07-08 | Glaxosmithkline Biologicals Sa | Hpv-16 and -18 l1 vlp vaccine |
| MY140664A (en) * | 2003-09-29 | 2010-01-15 | Merck Sharp & Dohme | Optimized expression of hpv 45 l1 in yeast |
-
2006
- 2006-04-24 CA CA002606092A patent/CA2606092A1/en not_active Abandoned
- 2006-04-24 KR KR1020077027497A patent/KR20080005585A/ko not_active Ceased
- 2006-04-24 MX MX2007013472A patent/MX2007013472A/es unknown
- 2006-04-24 AR AR20060101619A patent/AR054259A1/es not_active Application Discontinuation
- 2006-04-24 SG SG201000794-6A patent/SG159525A1/en unknown
- 2006-04-24 US US11/912,687 patent/US20090181052A1/en not_active Abandoned
- 2006-04-24 JP JP2008508156A patent/JP2008539184A/ja active Pending
- 2006-04-24 EA EA200702079A patent/EA013326B1/ru not_active IP Right Cessation
- 2006-04-24 WO PCT/EP2006/003918 patent/WO2006114312A2/en not_active Ceased
- 2006-04-24 EP EP06724609A patent/EP1877086A2/en not_active Ceased
- 2006-04-24 AU AU2006239422A patent/AU2006239422A1/en not_active Abandoned
-
2007
- 2007-10-11 NO NO20075194A patent/NO20075194L/no not_active Application Discontinuation
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2008534467A5 (https=) | ||
| JP2006512413A5 (https=) | ||
| JP2012010713A5 (https=) | ||
| JP2015028057A (ja) | ヒトパピローマウイルス感染症の治療又は予防のための複数型ｈｐｖペプチド組成物及び方法 | |
| CA2510457A1 (en) | Hpv-16 and -18 l1 vlp vaccine | |
| Toh et al. | Reduced dose human papillomavirus vaccination: an update of the current state-of-the-art | |
| US20170143818A1 (en) | Intradermal hpv peptide vaccination | |
| MX376568B (es) | Vacunas mejoradas para el virus del papiloma humano y métodos para utilizarlas. | |
| JP2008539184A5 (https=) | ||
| CN112618713A (zh) | 抗hpv及抗妇科炎症复合卵黄球蛋白组合物及凝胶剂 | |
| Roden et al. | The impact of preventive HPV vaccination | |
| US20090181052A1 (en) | Vaccine | |
| Ramet et al. | Position paper—HPV and the primary prevention of cancer; improving vaccine uptake by paediatricians | |
| JP2013540421A5 (https=) | ||
| US7858098B2 (en) | Vaccine | |
| RU2006143804A (ru) | Вакцина против вирусов папилломы человека hpv16 и hpv18 и по меньшей мере еще одного типа hpv, выбранного из hpv 31,45 или 52 | |
| JP2008539182A5 (https=) | ||
| CN101116745B (zh) | 人乳头瘤病毒的病毒样颗粒疫苗 | |
| Hariharan et al. | Genotypes of the human papillomavirus: Relevance to Indian field trials of the vaccine | |
| EA200702077A1 (ru) | Вакцина | |
| Bubeník | Human papillomavirus (HPV) and HPV-associated tumour vaccines | |
| Sitarz | HPV vaccines | |
| Yin | Development of vaccine against human papillomavirus types 3, 10 and 77 | |
| Guo et al. | Development Status and trend of HPV vaccine | |
| Uslimgazieva et al. | HUMAN PAPILLOMA VIRUS AND HUMAN PAPILLOMA VIRUS VACCINES |