JP2008535798A5 - - Google Patents
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- JP2008535798A5 JP2008535798A5 JP2008500972A JP2008500972A JP2008535798A5 JP 2008535798 A5 JP2008535798 A5 JP 2008535798A5 JP 2008500972 A JP2008500972 A JP 2008500972A JP 2008500972 A JP2008500972 A JP 2008500972A JP 2008535798 A5 JP2008535798 A5 JP 2008535798A5
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- Japan
- Prior art keywords
- hematocrit
- dose
- weekly
- hemoglobin
- visit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Description
用量に関連したヘマトクリット値の増加は、ベースラインと16回目の来院の間で観察された。ヘマトクリット値の変化はそれぞれ、800μg/kg週2回および毎週の群、ならびに400、200、100、50、および25μg/kg用量レベルのコホートにおいてそれぞれ、+3.8%、+2.7%、-0.2%、+1.6%、+0.6%、および+0.1%であった。同様の知見はヘモグロビンについても見られた。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US66063805P | 2005-03-11 | 2005-03-11 | |
US60/660,638 | 2005-03-11 | ||
PCT/US2006/008620 WO2006099154A1 (en) | 2005-03-11 | 2006-03-10 | Treating anemia by inhibition of vegf |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2008535798A JP2008535798A (ja) | 2008-09-04 |
JP2008535798A5 true JP2008535798A5 (ja) | 2012-11-01 |
JP5737826B2 JP5737826B2 (ja) | 2015-06-17 |
Family
ID=36676448
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2008500972A Expired - Fee Related JP5737826B2 (ja) | 2005-03-11 | 2006-03-10 | Vegfの阻害による貧血の処置 |
Country Status (6)
Country | Link |
---|---|
US (1) | US7351411B2 (ja) |
EP (1) | EP1855708A1 (ja) |
JP (1) | JP5737826B2 (ja) |
AU (1) | AU2006223314A1 (ja) |
CA (1) | CA2598452A1 (ja) |
WO (1) | WO2006099154A1 (ja) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7070959B1 (en) * | 1999-06-08 | 2006-07-04 | Regeneron Pharmaceuticals, Inc. | Modified chimeric polypeptides with improved pharmacokinetic properties |
US8986253B2 (en) | 2008-01-25 | 2015-03-24 | Tandem Diabetes Care, Inc. | Two chamber pumps and related methods |
US8408421B2 (en) | 2008-09-16 | 2013-04-02 | Tandem Diabetes Care, Inc. | Flow regulating stopcocks and related methods |
EP2334234A4 (en) | 2008-09-19 | 2013-03-20 | Tandem Diabetes Care Inc | DEVICE FOR MEASURING THE CONCENTRATION OF A SOLVED SUBSTANCE AND CORRESPONDING METHOD |
EP2932994B1 (en) | 2009-07-30 | 2017-11-08 | Tandem Diabetes Care, Inc. | New o-ring seal, and delivery mechanism and portable infusion pump system related thereto |
JO3283B1 (ar) | 2011-04-26 | 2018-09-16 | Sanofi Sa | تركيب يتضمن أفليبيرسيبت, حمض فولينيك, 5- فلورويوراسيل (5- Fu) وإرينوسيتان (FOLFIRI) |
US9180242B2 (en) | 2012-05-17 | 2015-11-10 | Tandem Diabetes Care, Inc. | Methods and devices for multiple fluid transfer |
US9555186B2 (en) | 2012-06-05 | 2017-01-31 | Tandem Diabetes Care, Inc. | Infusion pump system with disposable cartridge having pressure venting and pressure feedback |
NZ710658A (en) | 2013-02-18 | 2019-12-20 | Vegenics Pty Ltd | Ligand binding molecules and uses thereof |
US9173998B2 (en) | 2013-03-14 | 2015-11-03 | Tandem Diabetes Care, Inc. | System and method for detecting occlusions in an infusion pump |
US9914769B2 (en) | 2014-07-15 | 2018-03-13 | Kymab Limited | Precision medicine for cholesterol treatment |
GB201403775D0 (en) | 2014-03-04 | 2014-04-16 | Kymab Ltd | Antibodies, uses & methods |
US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
LT3170005T (lt) | 2014-07-18 | 2019-07-10 | Sanofi | Paciento, įtariamo, kad serga vėžiu, gydymo afliberceptu rezultato prognozavimo būdas |
EP3377101A4 (en) * | 2015-11-19 | 2019-08-07 | Zhuhai Tairuishang Biopharm Ltd. | VEGF BINDING METHODS AND COMPOSITIONS |
IL260323B1 (en) | 2015-12-30 | 2024-09-01 | Kodiak Sciences Inc | Antibodies and their conjugates |
KR101685532B1 (ko) * | 2016-04-26 | 2016-12-13 | 한국프라임제약주식회사 | 혈관내피성장인자 수용체 융합단백질 |
EP3534947A1 (en) | 2016-11-03 | 2019-09-11 | Kymab Limited | Antibodies, combinations comprising antibodies, biomarkers, uses & methods |
US12071476B2 (en) | 2018-03-02 | 2024-08-27 | Kodiak Sciences Inc. | IL-6 antibodies and fusion constructs and conjugates thereof |
US11426446B2 (en) | 2018-03-08 | 2022-08-30 | Coherus Biosciences, Inc. | Stable aqueous formulations of aflibercept |
US11667702B2 (en) | 2018-03-08 | 2023-06-06 | Coherus Biosciences, Inc. | Stable aqueous formulations of aflibercept |
US11912784B2 (en) | 2019-10-10 | 2024-02-27 | Kodiak Sciences Inc. | Methods of treating an eye disorder |
KR102426802B1 (ko) * | 2019-12-23 | 2022-07-28 | 한국프라임제약주식회사 | 혈관내피성장인자 수용체 융합단백질을 포함하는 신생혈관형성 관련 질환의 예방 및 치료를 위한 약학조성물 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6100071A (en) * | 1996-05-07 | 2000-08-08 | Genentech, Inc. | Receptors as novel inhibitors of vascular endothelial growth factor activity and processes for their production |
US6342221B1 (en) | 1999-04-28 | 2002-01-29 | Board Of Regents, The University Of Texas System | Antibody conjugate compositions for selectively inhibiting VEGF |
AUPQ592100A0 (en) | 2000-02-29 | 2000-03-23 | Council Of The Queensland Institute Of Medical Research, The | A method of treatment and prophylaxis |
CA2534197A1 (en) * | 2003-08-06 | 2005-02-24 | Thomas Jefferson University | Use of a vegf antagonist in combination with radiation therapy |
-
2006
- 2006-03-10 JP JP2008500972A patent/JP5737826B2/ja not_active Expired - Fee Related
- 2006-03-10 AU AU2006223314A patent/AU2006223314A1/en not_active Abandoned
- 2006-03-10 US US11/373,358 patent/US7351411B2/en active Active
- 2006-03-10 EP EP06737765A patent/EP1855708A1/en not_active Withdrawn
- 2006-03-10 CA CA002598452A patent/CA2598452A1/en not_active Abandoned
- 2006-03-10 WO PCT/US2006/008620 patent/WO2006099154A1/en active Application Filing
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