JP2008534621A - リオチロニンからなる放出制御型医薬組成物、並びにその製造方法及び使用方法 - Google Patents
リオチロニンからなる放出制御型医薬組成物、並びにその製造方法及び使用方法 Download PDFInfo
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- JP2008534621A JP2008534621A JP2008504498A JP2008504498A JP2008534621A JP 2008534621 A JP2008534621 A JP 2008534621A JP 2008504498 A JP2008504498 A JP 2008504498A JP 2008504498 A JP2008504498 A JP 2008504498A JP 2008534621 A JP2008534621 A JP 2008534621A
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- Prior art keywords
- pharmaceutical composition
- liothyronine
- pharmaceutically acceptable
- composition according
- acceptable salt
- Prior art date
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- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 description 1
- NLVXSWCKKBEXTG-UHFFFAOYSA-N vinylsulfonic acid Chemical compound OS(=O)(=O)C=C NLVXSWCKKBEXTG-UHFFFAOYSA-N 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- 239000000811 xylitol Substances 0.000 description 1
- 235000010447 xylitol Nutrition 0.000 description 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
- 229960002675 xylitol Drugs 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66662105P | 2005-03-31 | 2005-03-31 | |
| PCT/US2006/012272 WO2006105482A2 (en) | 2005-03-31 | 2006-03-31 | Controlled release pharmaceutical compositions of liothyronine and methods of making and using the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008534621A true JP2008534621A (ja) | 2008-08-28 |
| JP2008534621A5 JP2008534621A5 (enExample) | 2009-05-14 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008504498A Pending JP2008534621A (ja) | 2005-03-31 | 2006-03-31 | リオチロニンからなる放出制御型医薬組成物、並びにその製造方法及び使用方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20060246133A1 (enExample) |
| EP (1) | EP1863446A2 (enExample) |
| JP (1) | JP2008534621A (enExample) |
| KR (1) | KR20070119714A (enExample) |
| CN (1) | CN101175477A (enExample) |
| AU (1) | AU2006230557A1 (enExample) |
| BR (1) | BRPI0609779A2 (enExample) |
| CA (1) | CA2603313A1 (enExample) |
| IL (1) | IL185723A0 (enExample) |
| MX (1) | MX2007011826A (enExample) |
| WO (1) | WO2006105482A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2019515045A (ja) * | 2016-05-03 | 2019-06-06 | スペクトリックス セラピューティクス， エルエルシーＳｐｅｃｔｒｉｘ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｌｌｃ | 甲状腺ホルモン又はそのアナログを提供する組成物及び方法 |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0525461D0 (en) | 2005-12-15 | 2006-01-25 | Archimedes Dev Ltd | Pharmaceutical compositions |
| WO2008057464A2 (en) * | 2006-11-01 | 2008-05-15 | King Pharmaceuticals Research And Development, Inc. | Compositions and methods for improving the bioavailability of liothyronine |
| ATE553753T1 (de) * | 2007-02-16 | 2012-05-15 | Suisse Electronique Microtech | Überprüfungsverfahren |
| ITMI20112066A1 (it) * | 2011-11-14 | 2013-05-15 | Altergon Sa | Preparazione farmaceutica orale monodose di ormoni tiroidei t3 e t4 |
| US10695309B2 (en) * | 2017-03-31 | 2020-06-30 | Western New England University | Sustained-release liothyronine formulations, method of preparation and method of use thereof |
| US11964048B2 (en) * | 2020-12-18 | 2024-04-23 | Amneal Complex Products Research Llc | Sustained release compositions comprising liothyronine |
| EP4511009A1 (en) * | 2022-04-22 | 2025-02-26 | Prolevi Bio AB | Compositions for modified release of active ingredients |
| CN115645361B (zh) * | 2022-09-30 | 2023-11-21 | 天津市眼科医院 | 一种用于加强角膜生物力学性质的眼用制剂及t3的应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5200193A (en) * | 1987-04-22 | 1993-04-06 | Mcneilab, Inc. | Pharmaceutical sustained release matrix and process |
| US5009895A (en) * | 1990-02-02 | 1991-04-23 | Merck & Co., Inc. | Sustained release with high and low viscosity HPMC |
| EP0550108B1 (en) * | 1991-12-30 | 1998-03-18 | Akzo Nobel N.V. | Sustained release thyroactive composition |
| US5571840A (en) * | 1993-06-22 | 1996-11-05 | The Regents Of The University Of Michigan | Method for treating central nervous system ischemia |
| US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| US6555581B1 (en) * | 2001-02-15 | 2003-04-29 | Jones Pharma, Inc. | Levothyroxine compositions and methods |
-
2006
- 2006-03-30 AU AU2006230557A patent/AU2006230557A1/en not_active Abandoned
- 2006-03-31 WO PCT/US2006/012272 patent/WO2006105482A2/en not_active Ceased
- 2006-03-31 JP JP2008504498A patent/JP2008534621A/ja active Pending
- 2006-03-31 MX MX2007011826A patent/MX2007011826A/es not_active Application Discontinuation
- 2006-03-31 CN CNA2006800163341A patent/CN101175477A/zh active Pending
- 2006-03-31 KR KR1020077025071A patent/KR20070119714A/ko not_active Withdrawn
- 2006-03-31 US US11/396,420 patent/US20060246133A1/en not_active Abandoned
- 2006-03-31 CA CA002603313A patent/CA2603313A1/en not_active Abandoned
- 2006-03-31 EP EP06749147A patent/EP1863446A2/en not_active Withdrawn
- 2006-03-31 BR BRPI0609779-0A patent/BRPI0609779A2/pt not_active IP Right Cessation
-
2007
- 2007-09-04 IL IL185723A patent/IL185723A0/en unknown
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2019515045A (ja) * | 2016-05-03 | 2019-06-06 | スペクトリックス セラピューティクス， エルエルシーＳｐｅｃｔｒｉｘ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｌｌｃ | 甲状腺ホルモン又はそのアナログを提供する組成物及び方法 |
| JP2021073275A (ja) * | 2016-05-03 | 2021-05-13 | スペクトリックス セラピューティクス， エルエルシーＳｐｅｃｔｒｉｘ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｌｌｃ | 甲状腺ホルモン又はそのアナログを提供する組成物及び方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20060246133A1 (en) | 2006-11-02 |
| AU2006230557A1 (en) | 2006-10-05 |
| BRPI0609779A2 (pt) | 2011-10-18 |
| KR20070119714A (ko) | 2007-12-20 |
| CA2603313A1 (en) | 2006-10-05 |
| CN101175477A (zh) | 2008-05-07 |
| WO2006105482A2 (en) | 2006-10-05 |
| IL185723A0 (en) | 2008-01-06 |
| WO2006105482A3 (en) | 2006-12-07 |
| MX2007011826A (es) | 2007-11-22 |
| EP1863446A2 (en) | 2007-12-12 |
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