JP2008534524A5 - - Google Patents

Claims (15)

  Use of a skin whitening compound for cosmetic whitening of human skin, wherein the skin whitening compound is 2- [2- (4-methyl-3-cyclohexen-1-yl) -propyl] -cyclopentanone, 6 -Isopropyl-octahydro-naphthalen-2-one, 4,7,7-trimethyl-2- (3-methyl-but-2-enyl) -bicyclo [4.1.0] heptane-3-one, 1- ( 5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthalenyl) -ethanone, 1,1,2,3,3,8-hexamethyl-1,2 , 3,5,7,8-hexahydro-6-oxa-cyclopenta [b] naphthalene, 6,7-epoxy-1,1,2,4,4,7-hexamethyl-octahydro-naphthalene, 1,1,2 , 3,3-pentamethyl-1 2,3,5,6,7-hexahydro-inden-4-one, 1- (2,3,8,8-tetramethyl-1,2,3,4,5,6,7,8-octahydro- Naphthalen-2-yl) -ethanone, 2,2,3 ′, 7 ′, 7′-pentamethylspiro (1,3-dioxane-5,2′-norcaran), methyl-n-3,7-dimethyl- 7-hydroxyoctylidene anthranilate, 2- [3- (4-tert-butyl-phenyl) -2-methyl-propenylamino] -benzoic acid methyl ester, 2-[(2,4-dimethyl-cyclohex- 3-enylmethylene) -amino] -benzoic acid methyl ester, 2-methyl-4- (2,6,6-trimethyl-cyclohex-2-enyl) -butyraldehyde, 3- (3-isopropyl-phenyl)- Butyrua Dehydr, 3- (4-isobutyl-phenyl) -2-methyl-propionaldehyde, [1-methyl-2- (1,2,2, -trimethyl-bicyclo [3.1.0] hex-3-ylmethyl) -Cyclopropyl] -methanol, 2-ethyl-4- (2,2,3-trimethyl-cyclopent-3-en-1-yl) -but-2-en-1-ol, 3- (5,5, Sun containing 6-trimethylbicyclo [2.2.1] hept-2-yl) cyclohexanol, 3- (5,5,6-trimethylbicyclo [2.2.1] hept-2-yl) cyclohexanol Delaprocess products, 3-methyl-5- (2,2,3-trimethyl-cyclopent-3-enyl) -pentan-2-ol, 3-methyl-5- (2,2,3-trimethyl-3- Cyclopentene -1-yl) -4-penten-2-ol, (e) -oxacycloheptadec-10-en-2-one, 3-methylcyclotetradec-5-en-1-one, 4-methylcyclo Said use selected from the group consisting of tetradec-6-en-1-one and oxacyclohexadec-12-en-2-one. At least one skin lightening compounds and compositions comprising excipients optionally as defined in claim 1, applied at regular intervals to the skin of humans in a sufficient concentration, a method of lightening human skin. A method of forming a skin lightening personal care product, wherein at least one skin lightening compound as defined in claim 1 is mixed in a personal care product formulation at a concentration of 0.1-2% (w / v). As a first step, the composition comprises at least one compound selected from skin lightening compounds as defined in claim 1 and arbutin, deoxyarbutin, octadecenedioic acid, kojic acid, embricanin A, embricanin B The method according to claim 3 , wherein at least one component selected from the group consisting of: ascorbic acid, a derivative of ascorbic acid, a perfume component, a solvent, an additive, and an excipient is formed. (A) at least 30% (w / w), skin lightening compounds as defined in claim 1 of at least 2,
(B) up to 70% (w / w) any ingredient selected from one or more additional perfume ingredients including additives, excipients and solvents used in perfume,
A skin whitening fragrance composition. (E) -oxacycloheptadec-10-en-2-one or 3-methylcyclotetradec-5-en-1-one, 4-methylcyclotetradec-6-en-1-one and oxacyclohexa At least one compound selected from the group consisting of dec-12-en-2-one, and arbutin, octadecenedioic acid, deoxyarbutin, kojic acid, embryonicin A, embryonicin B, ascorbic acid, and ascorbic acid The skin whitening fragrance composition according to claim 5 , comprising at least one skin whitening compound selected from the group consisting of derivatives. A method for producing a skin whitening personal care product, wherein the composition as defined in claim 5 or 6 is mixed with a personal care product formulation. A skin whitening personal care product comprising at least 0.1% (w / v) of the composition according to claim 5 , 6 or 7 . A skin lightening personal care product comprising at least two skin lightening compounds as defined in claim 1 in a total concentration of 0.1% to 1%.   (E) -oxacycloheptadec-10-en-2-one, 3-methylcyclotetradec-5-en-1-one, 4-methylcyclotetradec-6-en-1-one, and oxacyclohex At least one skin lightening compound selected from the group consisting of sadec-12-en-2-one, and arbutin, deoxyarbutin, octadecenedioic acid, kojic acid, embryonicin A, embryonicin B, ascorbic acid, and A skin whitening personal care product comprising at least one compound selected from the group consisting of derivatives of ascorbic acid. A method of manufacturing a skin whitening personal care product,
at least one skin lightening compounds as defined in a) claim 1, and mixed in a personal care product formulations, by forming a personal care product, to provide a personal care product,
b) packaging the personal care product;
c) providing the packaged personal care product with instructions for cosmetic skin whitening;
The method comprising the steps of:   12. The method of claim 11, wherein the instructions for use are for applying a personal care product to the pigmented or over-deposited skin in an amount sufficient to periodically obtain a skin lightening effect. . The personal care product has at least one skin lightening compound as defined in claim 1 in a concentration of 0.1% to 2%, and the instructions for use include the personal care product, pigmented or over-deposited. 13. The method of claim 12 , wherein the method is for application to the skin thoroughly and at least once a day, preferably in an amount of 5-50 mg / cm < ² > or a thickness of 0.05-0.5 mm. A method of whitening the skin by regularly applying a sufficient amount of a compound as defined in claim 1 to human skin that is pigmented or over-deposited. The personal care product has at least one skin lightening compound as defined in any of claims 1 to 5 in a concentration of 0.1 to 2%, which is at least once a day, 5 to 50 mg / cm. 15. The method of claim 14 , wherein the method is applied to the skin in an amount of ² or a thickness of 0.05 to 0.5 mm.