JP2008531710A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2008531710A5 JP2008531710A5 JP2007558177A JP2007558177A JP2008531710A5 JP 2008531710 A5 JP2008531710 A5 JP 2008531710A5 JP 2007558177 A JP2007558177 A JP 2007558177A JP 2007558177 A JP2007558177 A JP 2007558177A JP 2008531710 A5 JP2008531710 A5 JP 2008531710A5
- Authority
- JP
- Japan
- Prior art keywords
- agent
- cell
- sod protein
- pyrimethamine
- administering
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 102000007399 Nuclear hormone receptor Human genes 0.000 claims 1
- 108020005497 Nuclear hormone receptor Proteins 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 108020004017 nuclear receptors Proteins 0.000 claims 1
- 239000002831 pharmacologic agent Substances 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- WKSAUQYGYAYLPV-UHFFFAOYSA-N pyrimethamine Chemical compound CCC1=NC(N)=NC(N)=C1C1=CC=C(Cl)C=C1 WKSAUQYGYAYLPV-UHFFFAOYSA-N 0.000 claims 1
- 229960000611 pyrimethamine Drugs 0.000 claims 1
- 238000013518 transcription Methods 0.000 claims 1
- 230000035897 transcription Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65850505P | 2005-03-04 | 2005-03-04 | |
| PCT/US2006/007257 WO2006096405A2 (en) | 2005-03-04 | 2006-03-01 | Treatment of amyotrophic lateral sclerosis with pyrimethamine and analogues |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008531710A JP2008531710A (ja) | 2008-08-14 |
| JP2008531710A5 true JP2008531710A5 (https=) | 2009-11-26 |
Family
ID=36953835
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007558177A Pending JP2008531710A (ja) | 2005-03-04 | 2006-03-01 | 神経変性疾患の調節 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20060211645A1 (https=) |
| EP (1) | EP1917017B1 (https=) |
| JP (1) | JP2008531710A (https=) |
| CN (1) | CN101184493A (https=) |
| AT (1) | ATE456953T1 (https=) |
| AU (1) | AU2006220919A1 (https=) |
| CA (1) | CA2600067A1 (https=) |
| DE (1) | DE602006012115D1 (https=) |
| ES (1) | ES2340708T3 (https=) |
| WO (1) | WO2006096405A2 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060211673A1 (en) * | 2005-03-04 | 2006-09-21 | Alsgen, Llc | Modulation of neurodegenerative diseases through the estrogen receptor |
| CN101232888A (zh) * | 2005-03-04 | 2008-07-30 | 阿尔斯根公司 | 用炔诺酮及其类似物治疗肌萎缩性侧索硬化 |
| US20070135437A1 (en) * | 2005-03-04 | 2007-06-14 | Alsgen, Inc. | Modulation of neurodegenerative diseases |
| WO2008046056A1 (en) * | 2006-10-13 | 2008-04-17 | Welldoc Communications, Inc. | Reduction of nonspecific binding in nucleic acid assays and nucleic acid synthesis reactions |
| WO2009067493A2 (en) * | 2007-11-19 | 2009-05-28 | Envivo Pharmaceuticals, Inc. | 1,3,5 tri-subtituted benzenes for treatment of alzheimer's disease and other disorders |
| JP2011507909A (ja) | 2007-12-20 | 2011-03-10 | エンビボ ファーマシューティカルズ インコーポレイテッド | 四置換ベンゼン |
| AR076601A1 (es) | 2009-05-21 | 2011-06-22 | Chlorion Pharma Inc | Pirimidinas como agentes terapeuticos |
| GB201015079D0 (en) | 2010-09-10 | 2010-10-27 | Helperby Therapeutics Ltd | Novel use |
| KR20180084153A (ko) * | 2011-06-10 | 2018-07-24 | 메르크 파텐트 게엠베하 | Btk 억제 활성을 갖는 피리미딘 및 피리딘 화합물의 조성물 및 제조방법 |
| CN104398517A (zh) * | 2014-11-28 | 2015-03-11 | 四川大学 | 乙胺嘧啶的新用途及治疗肿瘤的药物组合物 |
| KR20210056931A (ko) * | 2019-11-11 | 2021-05-20 | 에스케이케미칼 주식회사 | 피리메타민을 유효성분으로 포함하는 면역 관련 질환의 치료 또는 예방용 약학 조성물 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5231170A (en) * | 1986-08-27 | 1993-07-27 | Paul Averback | Antibodies to dense microspheres |
| US5866562A (en) * | 1996-10-25 | 1999-02-02 | Bayer Aktiengesellschaft | Ring-bridged bis-quinolines |
| US7442629B2 (en) * | 2004-09-24 | 2008-10-28 | President & Fellows Of Harvard College | Femtosecond laser-induced formation of submicrometer spikes on a semiconductor substrate |
| US7589105B2 (en) * | 2001-11-28 | 2009-09-15 | Btg International Limited | Preventives or remedies for alzheimer's disease, or amyloid protein fibril-formation inhibitors, which include a nitrogen-containing heteroaryl compound |
| DK1483247T3 (da) * | 2002-03-13 | 2009-08-17 | Euro Celtique Sa | Arylsubstituerede pyrimidiner og anvendelsen deraf |
| US20050026823A1 (en) * | 2003-06-20 | 2005-02-03 | Biomarin Pharmaceutical Inc. | Use of the chaperone receptor-associated protein (RAP) for the delivery of therapeutic compounds to the brain and other tissues |
| CN101232888A (zh) * | 2005-03-04 | 2008-07-30 | 阿尔斯根公司 | 用炔诺酮及其类似物治疗肌萎缩性侧索硬化 |
| US20070135437A1 (en) * | 2005-03-04 | 2007-06-14 | Alsgen, Inc. | Modulation of neurodegenerative diseases |
-
2006
- 2006-03-01 US US11/365,462 patent/US20060211645A1/en not_active Abandoned
- 2006-03-01 CA CA002600067A patent/CA2600067A1/en not_active Abandoned
- 2006-03-01 AU AU2006220919A patent/AU2006220919A1/en not_active Abandoned
- 2006-03-01 AT AT06736552T patent/ATE456953T1/de not_active IP Right Cessation
- 2006-03-01 JP JP2007558177A patent/JP2008531710A/ja active Pending
- 2006-03-01 DE DE602006012115T patent/DE602006012115D1/de not_active Expired - Lifetime
- 2006-03-01 EP EP06736552A patent/EP1917017B1/en not_active Expired - Lifetime
- 2006-03-01 ES ES06736552T patent/ES2340708T3/es not_active Expired - Lifetime
- 2006-03-01 CN CNA2006800153119A patent/CN101184493A/zh active Pending
- 2006-03-01 WO PCT/US2006/007257 patent/WO2006096405A2/en not_active Ceased
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO2020004I1 (no) | Larotrektinib og/eller farmasøytisk akseptable salter derav, særlig larotrektinibsulfat inkludert larotrektinibhydrogensulfat | |
| JP2010539123A5 (https=) | ||
| JP2011511805A5 (https=) | ||
| JP2007527914A5 (https=) | ||
| JP2010535151A5 (https=) | ||
| IL192374A0 (en) | Method of producing drug-containing wax matrix particles, extruder to be used in the method and sustained-release preparation containing cilostazol | |
| BRPI0719762A2 (pt) | Anticorpo, composição farmacêutica, polipeptídeo, polinucleotídeo isolado, plasmídeo, célula isolada, e, métodos para fabricar um polipeptídeo que se liga especificamente ao receptor il-17 a, para tratar um estado de doença associado com a ativação de il-17ra em um paciente, para inibir a produção de pelo menos uma citocina, quimiocina, metaloproteinase de matriz ou contra molécula associada com a ativação de il-17ra e para tratar inflamação e doneça autoimune em um paciente. | |
| JP2008531710A5 (https=) | ||
| IL189555A0 (en) | Compositions of cells enriched for combinations of various stem and progenitor cell populations, methods of use thereof and methods of private banking thereof | |
| NO20085420L (no) | Farmasøytisk formulering med fenylefrin og preparater for absorpsjon i tykktarmen | |
| EP2085078A4 (en) | OSMOTIC PUMP TABLET WITH CONTROLLED POROSITY OF HIGHLY PERMEABLE MEDICINES AND PREPARATION METHOD THEREOF | |
| JP2008013542A5 (https=) | ||
| WO2007124408A3 (en) | Hydrogen sensor | |
| IL198845A (en) | An extended-release peptide preparation, a process for its preparation and use for drug preparation | |
| TWD137077S1 (zh) | 燃料電池之計量閥 | |
| CL2008001563A1 (es) | Compuestos derivados de benzodioxanos condensados con heterociclos; metodo de preparacion; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como depresion, ansiedad, crisis de panico, entre otras. | |
| JP2010528620A5 (https=) | ||
| IL179884A0 (en) | Fuel cells, micro-fuel cells and methods for the production thereof | |
| JP2008536808A5 (https=) | ||
| JP2011505864A5 (https=) | ||
| EP2380973A4 (en) | PREPARATION BASED ON REPROGRAMMABLE CELL SIGNALING STEM CELLS, METHOD OF MAKING THE PREPARATION AND USE THEREOF | |
| JP2009536193A5 (https=) | ||
| GB0620255D0 (en) | Antibody and uses thereof | |
| Bader et al. | Geometric representations of GL (n, R), cellular Hecke algebras and the embedding problem | |
| JP2011034125A5 (https=) |