JP2008530171A - 新規なジアザ二環系アリール誘導体及びそれらの医療上の使用 - Google Patents
新規なジアザ二環系アリール誘導体及びそれらの医療上の使用 Download PDFInfo
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- JP2008530171A JP2008530171A JP2007555581A JP2007555581A JP2008530171A JP 2008530171 A JP2008530171 A JP 2008530171A JP 2007555581 A JP2007555581 A JP 2007555581A JP 2007555581 A JP2007555581 A JP 2007555581A JP 2008530171 A JP2008530171 A JP 2008530171A
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Classifications
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- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
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- Endocrinology (AREA)
- Pulmonology (AREA)
- Addiction (AREA)
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- Gynecology & Obstetrics (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Rheumatology (AREA)
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- Obesity (AREA)
- Child & Adolescent Psychology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200500229 | 2005-02-16 | ||
| US65351205P | 2005-02-17 | 2005-02-17 | |
| PCT/EP2006/050873 WO2006087305A1 (en) | 2005-02-16 | 2006-02-13 | Novel diazabicyclic aryl derivatives and their medical use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008530171A true JP2008530171A (ja) | 2008-08-07 |
| JP2008530171A5 JP2008530171A5 (https=) | 2009-04-02 |
Family
ID=36283929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007555581A Abandoned JP2008530171A (ja) | 2005-02-16 | 2006-02-13 | 新規なジアザ二環系アリール誘導体及びそれらの医療上の使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7750011B2 (https=) |
| EP (1) | EP1866314B1 (https=) |
| JP (1) | JP2008530171A (https=) |
| AT (1) | ATE481407T1 (https=) |
| DE (1) | DE602006016926D1 (https=) |
| WO (1) | WO2006087305A1 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0220581D0 (en) * | 2002-09-04 | 2002-10-09 | Novartis Ag | Organic Compound |
| PE20060437A1 (es) * | 2004-06-18 | 2006-06-08 | Novartis Ag | COMPUESTOS AZA-BICICLONONANOS COMO LIGANDOS COLINERGICOS DE nAChR |
| GB0415746D0 (en) | 2004-07-14 | 2004-08-18 | Novartis Ag | Organic compounds |
| GB0521508D0 (en) * | 2005-10-21 | 2005-11-30 | Novartis Ag | Organic compounds |
| GB0525673D0 (en) | 2005-12-16 | 2006-01-25 | Novartis Ag | Organic compounds |
| GB0525672D0 (en) | 2005-12-16 | 2006-01-25 | Novartis Ag | Organic compounds |
| DK2076508T3 (da) * | 2006-10-18 | 2011-02-21 | Pfizer Prod Inc | Biaryl-ether-urinstof-forbindelser |
| CA2706974A1 (en) * | 2007-11-30 | 2009-06-04 | Neurosearch A/S | Novel carboxylic acid 4-phenylazo-phenyl ester derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
| SG192078A1 (en) | 2011-02-03 | 2013-08-30 | Lupin Ltd | Pyrrole derivatives used as modulators of alpha7 nachr |
| ES2594409T3 (es) | 2011-02-23 | 2016-12-20 | Lupin Limited | Derivados de heteroarilo como moduladores del nAChR á7 |
| WO2012131576A1 (en) | 2011-03-31 | 2012-10-04 | Lupin Limited | Pyrrole derivatives as nicotinic acetylcholine receptor modulators for use in the treatment of neurodegenerative disorders such as alzheimer's and parkinson's disease |
| EP2729455B1 (en) | 2011-07-05 | 2016-09-14 | Lupin Limited | Biaryl derivatives as nachr modulators |
| NZ629453A (en) | 2012-03-06 | 2016-04-29 | Lupin Ltd | Thiazole derivatives as alpha 7 nachr modulators |
| US20150299178A1 (en) | 2012-11-12 | 2015-10-22 | Lupin Limited | Thiazole Derivatives as Alpha 7 NACHR Modulators |
| US9617211B2 (en) | 2013-01-16 | 2017-04-11 | Lupin Limited | Pyrrole derivatives as alpha 7 nAChR modulators |
| US9617210B2 (en) | 2013-03-13 | 2017-04-11 | Lupin Limited | Pyrrole derivatives as alpha 7 NACHR modulators |
| TW201446243A (zh) | 2013-06-03 | 2014-12-16 | Lupin Ltd | 4-(5-(4-氯苯基)-2-(2-環丙基乙醯基)-1,4-二甲基-1氫-吡咯-3-基)苯磺醯胺作為α7尼古丁乙醯膽鹼受體調節劑 |
| AU2014282886A1 (en) | 2013-06-17 | 2015-12-17 | Lupin Limited | Pyrrole derivatives as alpha 7 nAChR modulators |
| EA202092441A1 (ru) | 2016-06-07 | 2021-05-21 | Джакобио Фармасьютикалс Ко., Лтд. | Новые гетероциклические производные, применимые в качестве ингибиторов shp2 |
| KR20240026521A (ko) | 2017-03-23 | 2024-02-28 | 자코바이오 파마슈티칼스 컴퍼니 리미티드 | Shp2 억제제로서 유용한 신규한 헤테로환형 유도체 |
| CN112839935A (zh) | 2018-09-26 | 2021-05-25 | 北京加科思新药研发有限公司 | 可用作shp2抑制剂的新型杂环衍生物 |
| CN114409669B (zh) * | 2022-01-24 | 2023-06-23 | 云南民族大学 | 一种氧杂降冰片烯环上c-5位炔基取代的斑蝥素衍生物及其制备方法与应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5478939A (en) * | 1994-07-20 | 1995-12-26 | American Cyanamid Company | (R,R) and (S,S) 2,5-diazabicyclo [2,2,1]heptane derivatives |
| GB9803411D0 (en) | 1998-02-18 | 1998-04-15 | Smithkline Beecham Plc | Novel compounds |
| FR2786769B1 (fr) | 1998-12-04 | 2002-10-25 | Synthelabo | Derives de 2,5-diazabicyclo[2.2.1]heptane, leur preparation et leur application en therapeutique |
| TR200102162T2 (tr) | 1999-01-29 | 2001-12-21 | Abbott Laboratories | Nikotinik asetilkolin reseptör ligandları olarak diazabisiklik türevler. |
| DE60310548T2 (de) | 2002-05-07 | 2007-05-10 | Neurosearch A/S | Diazabicyclische biarylderivate |
| US7220741B2 (en) | 2002-09-30 | 2007-05-22 | Neurosearch A/S | 1,4-diazabicycloalkane derivatives, their preparation and use |
| DK1562945T3 (da) | 2002-11-11 | 2007-03-05 | Neurosearch As | Hidtil ukendte diazebicykliske biarylderivater |
| MXPA06001202A (es) * | 2003-07-29 | 2006-08-31 | Xenon Pharmaceuticals Inc | Derivados piridilo y su uso como agentes terapeuticos. |
| CN1829701A (zh) * | 2003-07-30 | 2006-09-06 | 泽农医药公司 | 哌嗪衍生物和它们作为治疗剂的用途 |
| ATE450263T1 (de) | 2004-02-04 | 2009-12-15 | Neurosearch As | Diazabicyclische aryl-derivate als cholinerge rezeptor-modulatoren |
-
2006
- 2006-02-13 AT AT06708215T patent/ATE481407T1/de not_active IP Right Cessation
- 2006-02-13 WO PCT/EP2006/050873 patent/WO2006087305A1/en not_active Ceased
- 2006-02-13 JP JP2007555581A patent/JP2008530171A/ja not_active Abandoned
- 2006-02-13 US US11/884,345 patent/US7750011B2/en not_active Expired - Fee Related
- 2006-02-13 EP EP06708215A patent/EP1866314B1/en not_active Expired - Lifetime
- 2006-02-13 DE DE602006016926T patent/DE602006016926D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1866314B1 (en) | 2010-09-15 |
| ATE481407T1 (de) | 2010-10-15 |
| US20080161314A1 (en) | 2008-07-03 |
| EP1866314A1 (en) | 2007-12-19 |
| US7750011B2 (en) | 2010-07-06 |
| DE602006016926D1 (de) | 2010-10-28 |
| WO2006087305A1 (en) | 2006-08-24 |
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Free format text: JAPANESE INTERMEDIATE CODE: A762 Effective date: 20110217 |