JP2008527998A - Ｎｓｃｌｃの診断のためのｇｉｔｒ抗体 - Google Patents

Ｎｓｃｌｃの診断のためのｇｉｔｒ抗体 Download PDF

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Publication number
JP2008527998A
JP2008527998A JP2007552289A JP2007552289A JP2008527998A JP 2008527998 A JP2008527998 A JP 2008527998A JP 2007552289 A JP2007552289 A JP 2007552289A JP 2007552289 A JP2007552289 A JP 2007552289A JP 2008527998 A JP2008527998 A JP 2008527998A
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JP
Japan
Prior art keywords
antibody
gene
cell
cancer
cells
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Withdrawn
Application number
JP2007552289A
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English (en)
Japanese (ja)
Inventor
ベヴァリー タイヒャー
スリーニバース シャンカラ
ブルース ロバーツ
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Genzyme Corp
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Genzyme Corp
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Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of JP2008527998A publication Critical patent/JP2008527998A/ja
Withdrawn legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2007552289A 2005-01-19 2006-01-19 Ｎｓｃｌｃの診断のためのｇｉｔｒ抗体 Withdrawn JP2008527998A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64534905P 2005-01-19 2005-01-19
PCT/US2006/002050 WO2006078911A2 (fr) 2005-01-19 2006-01-19 Anticorps anti-gitr pour le diagnostic du cancer du poumon non a petites cellules (cpnpc)

Publications (1)

Publication Number Publication Date
JP2008527998A true JP2008527998A (ja) 2008-07-31

Family

ID=36692925

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007552289A Withdrawn JP2008527998A (ja) 2005-01-19 2006-01-19 Ｎｓｃｌｃの診断のためのｇｉｔｒ抗体

Country Status (8)

Country Link
EP (1) EP1856281A2 (fr)
JP (1) JP2008527998A (fr)
CN (1) CN101133167A (fr)
AU (1) AU2006206343A1 (fr)
BR (1) BRPI0606685A2 (fr)
CA (1) CA2592330A1 (fr)
IL (1) IL184343A0 (fr)
WO (1) WO2006078911A2 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015071625A (ja) * 2014-11-28 2015-04-16 学校法人 学習院 含ホウ素ポルフィリン誘導体
JP2018519508A (ja) * 2015-06-03 2018-07-19 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ 癌診断用抗ｇｉｔｒ抗体

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2343320T3 (da) 2005-03-25 2018-01-29 Gitr Inc Anti-gitr-antistoffer og anvendelser deraf
EP2175884B8 (fr) 2007-07-12 2017-02-22 GITR, Inc. Thérapies combinées utilisant des molécules de liaison au gitr
LT3023438T (lt) 2009-09-03 2020-05-11 Merck Sharp & Dohme Corp. Anti-gitr antikūnai
KR101566539B1 (ko) 2012-06-08 2015-11-05 국립암센터 신규한 Ｔｈ2 세포 전환용 에피토프 및 이의 용도
TW201605896A (zh) 2013-08-30 2016-02-16 安美基股份有限公司 Gitr抗原結合蛋白
SG10201810507WA (en) 2014-06-06 2018-12-28 Bristol Myers Squibb Co Antibodies against glucocorticoid-induced tumor necrosis factor receptor (gitr) and uses thereof
WO2017087678A2 (fr) 2015-11-19 2017-05-26 Bristol-Myers Squibb Company Anticorps dirigés contre un récepteur du facteur de nécrose tumorale induit par glucocorticoïdes (gitr) et leurs utilisations
EP3426297A4 (fr) * 2016-03-08 2019-08-14 Janssen Biotech, Inc. Anticorps anti-gitr, méthodes et utilisations
WO2018162376A1 (fr) * 2017-03-07 2018-09-13 F. Hoffmann-La Roche Ag Méthode de recherche de variants d'anticorps spécifiques d'un antigène alternatif
KR20200006115A (ko) 2017-05-16 2020-01-17 브리스톨-마이어스 스큅 컴퍼니 항-gitr 효능제 항체에 의한 암의 치료
CN109777872B (zh) * 2017-11-15 2021-04-02 北京大学 肺癌中的t细胞亚群及其特征基因

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6689607B2 (en) * 1997-10-21 2004-02-10 Human Genome Sciences, Inc. Human tumor, necrosis factor receptor-like proteins TR11, TR11SV1 and TR11SV2
US6503184B1 (en) * 1997-10-21 2003-01-07 Human Genome Sciences, Inc. Human tumor necrosis factor receptor-like proteins TR11, TR11SV1 and TR11SV2
US20030138426A1 (en) * 1997-10-21 2003-07-24 Human Genome Sciences, Inc. Human tumor necrosis factor receptor-like proteins TR11, TR11SV1, and TR11SV2
JP2001520039A (ja) * 1997-10-21 2001-10-30 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド ヒト腫瘍壊死因子レセプター様タンパク質、ｔｒ１１，ｔｒ１１ｓｖ１およびｔｒ１１ｓｖ２
WO2000050459A1 (fr) * 1999-02-24 2000-08-31 Human Genome Sciences, Inc. Proteines tr11, tr11sv1, et tr11sv2 du type recepteur tnf humain
AU2004245998A1 (en) * 2003-06-04 2004-12-16 The Government of the United States as represented by The Secretary of the Department of Health and Human Services, Centres for Disease Control and Prevention PNI microarray and uses

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015071625A (ja) * 2014-11-28 2015-04-16 学校法人 学習院 含ホウ素ポルフィリン誘導体
JP2018519508A (ja) * 2015-06-03 2018-07-19 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ 癌診断用抗ｇｉｔｒ抗体

Also Published As

Publication number Publication date
BRPI0606685A2 (pt) 2009-07-14
EP1856281A2 (fr) 2007-11-21
CN101133167A (zh) 2008-02-27
WO2006078911A2 (fr) 2006-07-27
IL184343A0 (en) 2007-10-31
AU2006206343A1 (en) 2006-07-27
CA2592330A1 (fr) 2006-07-27
WO2006078911A3 (fr) 2007-06-28

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Effective date: 20090407