CA2592330A1 - Anticorps anti-gitr pour le diagnostic du cancer du poumon non a petites cellules (cpnpc) - Google Patents

Anticorps anti-gitr pour le diagnostic du cancer du poumon non a petites cellules (cpnpc) Download PDF

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Publication number
CA2592330A1
CA2592330A1 CA002592330A CA2592330A CA2592330A1 CA 2592330 A1 CA2592330 A1 CA 2592330A1 CA 002592330 A CA002592330 A CA 002592330A CA 2592330 A CA2592330 A CA 2592330A CA 2592330 A1 CA2592330 A1 CA 2592330A1
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CA
Canada
Prior art keywords
antibody
gene
cell
antibodies
expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002592330A
Other languages
English (en)
Inventor
Beverly Teicher
Srinivas Shankara
Bruce Roberts
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genzyme Corp
Original Assignee
Genzyme Corporation
Beverly Teicher
Srinivas Shankara
Bruce Roberts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corporation, Beverly Teicher, Srinivas Shankara, Bruce Roberts filed Critical Genzyme Corporation
Publication of CA2592330A1 publication Critical patent/CA2592330A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA002592330A 2005-01-19 2006-01-19 Anticorps anti-gitr pour le diagnostic du cancer du poumon non a petites cellules (cpnpc) Abandoned CA2592330A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US64534905P 2005-01-19 2005-01-19
US60/645,349 2005-01-19
PCT/US2006/002050 WO2006078911A2 (fr) 2005-01-19 2006-01-19 Anticorps anti-gitr pour le diagnostic du cancer du poumon non a petites cellules (cpnpc)

Publications (1)

Publication Number Publication Date
CA2592330A1 true CA2592330A1 (fr) 2006-07-27

Family

ID=36692925

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002592330A Abandoned CA2592330A1 (fr) 2005-01-19 2006-01-19 Anticorps anti-gitr pour le diagnostic du cancer du poumon non a petites cellules (cpnpc)

Country Status (8)

Country Link
EP (1) EP1856281A2 (fr)
JP (1) JP2008527998A (fr)
CN (1) CN101133167A (fr)
AU (1) AU2006206343A1 (fr)
BR (1) BRPI0606685A2 (fr)
CA (1) CA2592330A1 (fr)
IL (1) IL184343A0 (fr)
WO (1) WO2006078911A2 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2343320T (pt) 2005-03-25 2018-01-23 Gitr Inc Anticorpos anti-gitr e as suas utilizações
AU2008275589B2 (en) 2007-07-12 2013-11-21 Gitr, Inc. Combination therapies employing GITR binding molecules
BR112012004823B1 (pt) 2009-09-03 2021-11-30 Merck Sharp & Dohme Corp Anticorpo ou fragmento de ligação de antígeno do mesmo, uso de um anticorpo ou um fragmento de ligação de antígeno do mesmo, e composição farmacêutica
KR101566539B1 (ko) 2012-06-08 2015-11-05 국립암센터 신규한 Ｔｈ2 세포 전환용 에피토프 및 이의 용도
TW201605896A (zh) 2013-08-30 2016-02-16 安美基股份有限公司 Gitr抗原結合蛋白
EP3998079A1 (fr) 2014-06-06 2022-05-18 Bristol-Myers Squibb Company Anticorps dirigés contre le récepteur du facteur de nécrose tumorale induit par glucocorticoïdes (gitr) et leurs procédés d'utilisation
JP5995207B2 (ja) * 2014-11-28 2016-09-21 学校法人 学習院 含ホウ素ポルフィリン誘導体
CA2988115A1 (fr) * 2015-06-03 2016-12-08 Bristol-Myers Squibb Company Anticorps anti-gitr pour le diagnostic du cancer
WO2017087678A2 (fr) 2015-11-19 2017-05-26 Bristol-Myers Squibb Company Anticorps dirigés contre un récepteur du facteur de nécrose tumorale induit par glucocorticoïdes (gitr) et leurs utilisations
MA43814A (fr) * 2016-03-08 2018-11-28 Janssen Biotech Inc Anticorps anti-gitr, méthodes et utilisations
WO2018162376A1 (fr) * 2017-03-07 2018-09-13 F. Hoffmann-La Roche Ag Méthode de recherche de variants d'anticorps spécifiques d'un antigène alternatif
KR20200006115A (ko) 2017-05-16 2020-01-17 브리스톨-마이어스 스큅 컴퍼니 항-gitr 효능제 항체에 의한 암의 치료
CN109777872B (zh) * 2017-11-15 2021-04-02 北京大学 肺癌中的t细胞亚群及其特征基因

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6509173B1 (en) * 1997-10-21 2003-01-21 Human Genome Sciences, Inc. Human tumor necrosis factor receptor-like proteins TR11, TR11SV1, and TR11SV2
US6689607B2 (en) * 1997-10-21 2004-02-10 Human Genome Sciences, Inc. Human tumor, necrosis factor receptor-like proteins TR11, TR11SV1 and TR11SV2
US6503184B1 (en) * 1997-10-21 2003-01-07 Human Genome Sciences, Inc. Human tumor necrosis factor receptor-like proteins TR11, TR11SV1 and TR11SV2
US20030138426A1 (en) * 1997-10-21 2003-07-24 Human Genome Sciences, Inc. Human tumor necrosis factor receptor-like proteins TR11, TR11SV1, and TR11SV2
AU3860100A (en) * 1999-02-24 2000-09-14 Human Genome Sciences, Inc. Human tumor necrosis factor receptor-like proteins tr11, tr11sv1, and tr11sv2
AU2004245998A1 (en) * 2003-06-04 2004-12-16 The Government of the United States as represented by The Secretary of the Department of Health and Human Services, Centres for Disease Control and Prevention PNI microarray and uses

Also Published As

Publication number Publication date
CN101133167A (zh) 2008-02-27
WO2006078911A2 (fr) 2006-07-27
EP1856281A2 (fr) 2007-11-21
BRPI0606685A2 (pt) 2009-07-14
AU2006206343A1 (en) 2006-07-27
IL184343A0 (en) 2007-10-31
WO2006078911A3 (fr) 2007-06-28
JP2008527998A (ja) 2008-07-31

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Legal Events

Date Code Title Description
FZDE Discontinued