JP2008527028A5 - - Google Patents

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Publication number
JP2008527028A5
JP2008527028A5 JP2007551726A JP2007551726A JP2008527028A5 JP 2008527028 A5 JP2008527028 A5 JP 2008527028A5 JP 2007551726 A JP2007551726 A JP 2007551726A JP 2007551726 A JP2007551726 A JP 2007551726A JP 2008527028 A5 JP2008527028 A5 JP 2008527028A5
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JP
Japan
Prior art keywords
synthase
leukotriene
activating protein
mpges
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2007551726A
Other languages
English (en)
Japanese (ja)
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JP2008527028A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/GB2005/004980 external-priority patent/WO2006077365A1/en
Publication of JP2008527028A publication Critical patent/JP2008527028A/ja
Publication of JP2008527028A5 publication Critical patent/JP2008527028A5/ja
Withdrawn legal-status Critical Current

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JP2007551726A 2005-01-19 2005-12-22 炎症の治療に有用なインドール類 Withdrawn JP2008527028A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64451905P 2005-01-19 2005-01-19
PCT/GB2005/004980 WO2006077365A1 (en) 2005-01-19 2005-12-22 Indoles useful in the treatment of inflammation

Publications (2)

Publication Number Publication Date
JP2008527028A JP2008527028A (ja) 2008-07-24
JP2008527028A5 true JP2008527028A5 (cg-RX-API-DMAC7.html) 2009-02-19

Family

ID=34956617

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007551726A Withdrawn JP2008527028A (ja) 2005-01-19 2005-12-22 炎症の治療に有用なインドール類

Country Status (5)

Country Link
US (1) US20090042949A1 (cg-RX-API-DMAC7.html)
EP (1) EP1838669A1 (cg-RX-API-DMAC7.html)
JP (1) JP2008527028A (cg-RX-API-DMAC7.html)
CA (1) CA2594773A1 (cg-RX-API-DMAC7.html)
WO (1) WO2006077365A1 (cg-RX-API-DMAC7.html)

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* Cited by examiner, † Cited by third party
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WO2006077364A1 (en) * 2005-01-19 2006-07-27 Biolipox Ab Indoles useful in the treatment of inflammation
WO2006077367A1 (en) * 2005-01-19 2006-07-27 Biolipox Ab Indoles useful in the treatment of inflamation
WO2006077366A1 (en) * 2005-01-19 2006-07-27 Biolipox Ab Indoles useful in the treatment of inflammation
US7797493B2 (en) * 2005-02-15 2010-09-14 Koninklijke Philips Electronics N.V. Enhancing performance of a memory unit of a data processing device by separating reading and fetching functionalities
US8399666B2 (en) 2005-11-04 2013-03-19 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
US7977359B2 (en) 2005-11-04 2011-07-12 Amira Pharmaceuticals, Inc. 5-lipdxygenase-activating protein (FLAP) inhibitors
GB2431927B (en) 2005-11-04 2010-03-17 Amira Pharmaceuticals Inc 5-Lipoxygenase-activating protein (FLAP) inhibitors
TW200920369A (en) 2007-10-26 2009-05-16 Amira Pharmaceuticals Inc 5-lipoxygenase activating protein (flap) inhibitor
JP5791500B2 (ja) 2008-05-23 2015-10-07 パンミラ ファーマシューティカルズ，エルエルシー． ５−リポキシゲナーゼ活性化タンパク質阻害剤
US8546431B2 (en) 2008-10-01 2013-10-01 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
WO2010076566A2 (en) 2008-12-30 2010-07-08 Biolipox Ab Indoles useful in the treatment of inflammation
US8293729B2 (en) 2009-06-24 2012-10-23 Boehringer Ingelheim International Gmbh Compounds, pharmaceutical composition and methods relating thereto
US8481731B2 (en) 2009-06-24 2013-07-09 Boehringer Ingelheim International Gmbh Compounds, pharmaceutical composition and methods relating thereto
JP2012211085A (ja) * 2009-08-12 2012-11-01 Kyowa Hakko Kirin Co Ltd ヘッジホッグシグナル阻害剤
GB201006846D0 (en) 2010-04-23 2010-06-09 Glaxo Group Ltd Novel compounds
WO2012145069A2 (en) * 2011-02-24 2012-10-26 The University Of Toledo Materials and methods useful to induce cell death via methuosis
JOP20130213B1 (ar) 2012-07-17 2021-08-17 Takeda Pharmaceuticals Co معارضات لمستقبلht3-5
NZ708928A (en) 2012-12-18 2020-04-24 Vertex Pharma Mannose derivatives for treating bacterial infections
AU2014248717B2 (en) 2013-03-12 2018-03-29 Vertex Pharmaceuticals Incorporated Mannose derivatives for treating bacterial infections
JP7055017B2 (ja) 2014-09-29 2022-04-15 武田薬品工業株式会社 結晶形の１－（１－メチル－１ｈ－ピラゾール－４－イル）－ｎ－（（１ｒ，５ｓ，７ｓ）－９－メチル－３－オキサ－９－アザビシクロ［３．３．１］ノナン－７－イル）－１ｈ－インドール－３－カルボキサミド
CA2978823C (en) 2014-12-29 2023-10-10 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Small molecule inhibitors of lactate dehydrogenase and methods of use thereof
CN107098846B (zh) * 2016-02-26 2020-10-09 中国医学科学院药物研究所 N-酰基磺酰胺类FBPase抑制剂、其制备方法、药物组合物及用途
WO2017210545A1 (en) 2016-06-02 2017-12-07 Cadent Therapeutics, Inc. Potassium channel modulators
EP3571193B1 (en) 2017-01-23 2021-12-01 Cadent Therapeutics, Inc. Potassium channel modulators
PL3461819T3 (pl) 2017-09-29 2020-11-30 Probiodrug Ag Inhibitory cyklazy glutaminylowej
MX2021004647A (es) 2018-10-22 2021-08-16 Novartis Ag Formas cristalinas de moduladores de los canales de potasio.
CN114302874B (zh) 2019-08-26 2025-02-25 国际药品株式会社 吲哚甲酰胺衍生物和包含吲哚甲酰胺衍生物的药物组合物
CN113967210B (zh) * 2020-07-24 2025-02-07 上海交通大学医学院附属瑞金医院 一种干扰整合素β3/Src相互作用的化合物的用途
CN116283946B (zh) * 2023-03-27 2024-05-07 武汉工程大学 5-(n-取代吲哚-5-基)异噁唑-3-甲酸衍生物及其合成方法和应用

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