JP2008527027A - 炎症の治療に有用なインドール類 - Google Patents

炎症の治療に有用なインドール類 Download PDF

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JP2008527027A
JP2008527027A JP2007551725A JP2007551725A JP2008527027A JP 2008527027 A JP2008527027 A JP 2008527027A JP 2007551725 A JP2007551725 A JP 2007551725A JP 2007551725 A JP2007551725 A JP 2007551725A JP 2008527027 A JP2008527027 A JP 2008527027A
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JP2008527027A5 (cg-RX-API-DMAC7.html
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ベンジャミン ペルクマン，
クリストファー オロフッソン，
マーティンス カツケヴィックス，
ヴィータ オゾラ，
エドガース スナ，
イバース カルヴィンス，
ピーテリス トラペンシーリス，
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Biolipox AB
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Biolipox AB
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Publication of JP2008527027A5 publication Critical patent/JP2008527027A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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  • Health & Medical Sciences (AREA)
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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Transplantation (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biotechnology (AREA)
  • Emergency Medicine (AREA)
JP2007551725A 2005-01-19 2005-12-22 炎症の治療に有用なインドール類 Withdrawn JP2008527027A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US64455405P 2005-01-19 2005-01-19
US64455305P 2005-01-19 2005-01-19
PCT/GB2005/004978 WO2006077364A1 (en) 2005-01-19 2005-12-22 Indoles useful in the treatment of inflammation

Publications (2)

Publication Number Publication Date
JP2008527027A true JP2008527027A (ja) 2008-07-24
JP2008527027A5 JP2008527027A5 (cg-RX-API-DMAC7.html) 2009-02-19

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JP2007551725A Withdrawn JP2008527027A (ja) 2005-01-19 2005-12-22 炎症の治療に有用なインドール類

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US (1) US20080249091A1 (cg-RX-API-DMAC7.html)
EP (1) EP1844013A1 (cg-RX-API-DMAC7.html)
JP (1) JP2008527027A (cg-RX-API-DMAC7.html)
AR (1) AR053993A1 (cg-RX-API-DMAC7.html)
CA (1) CA2594878A1 (cg-RX-API-DMAC7.html)
TW (1) TW200637820A (cg-RX-API-DMAC7.html)
WO (1) WO2006077364A1 (cg-RX-API-DMAC7.html)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011019060A1 (ja) * 2009-08-12 2011-02-17 協和発酵キリン株式会社 ヘッジホッグシグナル阻害剤
CN109665985A (zh) * 2018-11-30 2019-04-23 中国科学院广州生物医药与健康研究院 多取代吲哚类化合物及其应用

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EP1765775B1 (en) * 2004-06-18 2009-04-29 Biolipox AB Indoles useful in the treatment of inflammation
BRPI0512252A (pt) * 2004-06-18 2008-02-19 Biolipox Ab composto ou um sal farmaceuticamente aceitável do mesmo, formulação farmacêutica, uso de um composto, método de tratamento de uma doença, produto combinado, e, processo para a preparação de um composto
MXPA06014536A (es) * 2004-06-18 2007-06-05 Biolipox Ab Indoles utiles en el tratamiento de inflamacion.
WO2006077366A1 (en) * 2005-01-19 2006-07-27 Biolipox Ab Indoles useful in the treatment of inflammation
WO2006077367A1 (en) * 2005-01-19 2006-07-27 Biolipox Ab Indoles useful in the treatment of inflamation
US7977359B2 (en) 2005-11-04 2011-07-12 Amira Pharmaceuticals, Inc. 5-lipdxygenase-activating protein (FLAP) inhibitors
US8399666B2 (en) 2005-11-04 2013-03-19 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
GB2431927B (en) 2005-11-04 2010-03-17 Amira Pharmaceuticals Inc 5-Lipoxygenase-activating protein (FLAP) inhibitors
WO2008009924A2 (en) * 2006-07-18 2008-01-24 Biolipox Ab Indoles useful in the treatment of inflammation
CN101157688B (zh) * 2006-10-16 2010-09-08 复旦大学 6-苄氧基吲哚-2-甲酸糠醇酯衍生物及其制备方法和用途
US8293781B2 (en) 2007-03-29 2012-10-23 Daiichi Sankyo Company, Limited Indole derivatives having cPLA2 inhibiting activity and applications and production methods of the same
TW200920369A (en) 2007-10-26 2009-05-16 Amira Pharmaceuticals Inc 5-lipoxygenase activating protein (flap) inhibitor
JP5791500B2 (ja) 2008-05-23 2015-10-07 パンミラ ファーマシューティカルズ，エルエルシー． ５−リポキシゲナーゼ活性化タンパク質阻害剤
US8546431B2 (en) 2008-10-01 2013-10-01 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
US20100160351A1 (en) * 2008-12-19 2010-06-24 Nuon Therapeutics, Inc. Pharmaceutical compositions and methods for treating hyperuricemia and related disorders
WO2010071865A1 (en) 2008-12-19 2010-06-24 Nuon Therapeutics, Inc. Pharmaceutical compositions and methods for treating hyperuricemia and related disorders
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