JP2008526935A5 - - Google Patents

Info

Publication number

JP2008526935A5

JP2008526935A5 JP2007550830A JP2007550830A JP2008526935A5 JP 2008526935 A5 JP2008526935 A5 JP 2008526935A5 JP 2007550830 A JP2007550830 A JP 2007550830A JP 2007550830 A JP2007550830 A JP 2007550830A JP 2008526935 A5 JP2008526935 A5 JP 2008526935A5

Authority

JP

Japan

Prior art keywords

use according

drug

intended

wound

administration

Prior art date

2006-01-06

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
• Global Dossier
• Discuss

• 239000003814 drug Substances 0.000 claims 15
• 229940079593 drug Drugs 0.000 claims 14
• 206010052428 Wound Diseases 0.000 claims 10
• 208000027418 Wounds and injury Diseases 0.000 claims 10
• 108090000765 processed proteins & peptides Proteins 0.000 claims 5
• 231100000241 scar Toxicity 0.000 claims 5
• 125000000539 amino acid group Chemical group 0.000 claims 3
• 230000029663 wound healing Effects 0.000 claims 3
• 208000002847 Surgical Wound Diseases 0.000 claims 2
• 230000001684 chronic effect Effects 0.000 claims 2
• 230000035876 healing Effects 0.000 claims 2
• 230000001575 pathological effect Effects 0.000 claims 2
• GTORPNRZTBKYJB-AIEIIIEWSA-N (2s)-4-amino-2-[[(2s)-2-[[(2s,3s)-2-[[(2s)-6-amino-2-[[(2s)-2-[[(2s,3r)-2-[[(2s)-2-[[(2s)-2-[[(2s)-2-aminopropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-hydroxybutanoyl]amino]-4-methylsulfanylbutanoyl]amino]hexanoyl Chemical compound NC(N)=NCCC[C@@H](C(=O)N[C@@H](CC(N)=O)C(O)=O)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCSC)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCSC)NC(=O)[C@@H](NC(=O)[C@H](C)N)CC1=CC=C(O)C=C1 GTORPNRZTBKYJB-AIEIIIEWSA-N 0.000 claims 1
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
• 206010072170 Skin wound Diseases 0.000 claims 1
• 108010034537 alanyl-tyrosyl-methionyl-threonyl-methionyl-lysyl-isoleucyl-arginyl-asparagine Proteins 0.000 claims 1
• 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 1
• 238000002316 cosmetic surgery Methods 0.000 claims 1
• 230000028709 inflammatory response Effects 0.000 claims 1
• 238000002347 injection Methods 0.000 claims 1
• 239000007924 injection Substances 0.000 claims 1
• 238000004519 manufacturing process Methods 0.000 claims 1
• 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
• 230000001737 promoting effect Effects 0.000 claims 1
• 230000037390 scarring Effects 0.000 claims 1
• 238000011200 topical administration Methods 0.000 claims 1