JP2008524310A - 多発性硬化症の組み合せ治療 - Google Patents
多発性硬化症の組み合せ治療 Download PDFInfo
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Classifications
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
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- A—HUMAN NECESSITIES
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
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- A—HUMAN NECESSITIES
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- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
Landscapes
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Transplantation (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Electrotherapy Devices (AREA)
- Transplanting Machines (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63867404P | 2004-12-22 | 2004-12-22 | |
| EP04106910 | 2004-12-22 | ||
| PCT/EP2005/056943 WO2006067134A1 (en) | 2004-12-22 | 2005-12-20 | Combination treatment for multiple sclerosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2008524310A true JP2008524310A (ja) | 2008-07-10 |
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| JP2007547483A Withdrawn JP2008524310A (ja) | 2004-12-22 | 2005-12-20 | 多発性硬化症の組み合せ治療 |
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|---|---|
| US (1) | US20100129353A1 (enExample) |
| EP (1) | EP1835922B1 (enExample) |
| JP (1) | JP2008524310A (enExample) |
| AT (1) | ATE431740T1 (enExample) |
| AU (1) | AU2005318183B2 (enExample) |
| CA (1) | CA2590471A1 (enExample) |
| CY (1) | CY1109316T1 (enExample) |
| DE (1) | DE602005014570D1 (enExample) |
| DK (1) | DK1835922T3 (enExample) |
| ES (1) | ES2325552T3 (enExample) |
| HR (1) | HRP20090417T1 (enExample) |
| IL (1) | IL183924A (enExample) |
| NO (1) | NO20073635L (enExample) |
| PL (1) | PL1835922T3 (enExample) |
| PT (1) | PT1835922E (enExample) |
| SI (1) | SI1835922T1 (enExample) |
| WO (1) | WO2006067134A1 (enExample) |
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| AU2024282654A1 (en) | 2023-05-30 | 2025-12-04 | Paragon Therapeutics, Inc. | Alpha4beta7 integrin antibody compositions and methods of use |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2521565B1 (fr) * | 1982-02-17 | 1985-07-05 | Dior Sa Parfums Christian | Melange pulverulent de constituants lipidiques et de constituants hydrophobes, procede pour le preparer, phases lamellaires lipidiques hydratees et procede de fabrication, compositions pharmaceutiques ou cosmetiques comportant des phases lamellaires lipidiques hydratees |
| FR2534487B1 (fr) * | 1982-10-15 | 1988-06-10 | Dior Christian Parfums | Procede d'homogeneisation de dispersions de phases lamellaires lipidiques hydratees, et suspensions obtenues par ce procede |
| US5310732A (en) * | 1986-02-03 | 1994-05-10 | The Scripps Research Institute | 2-halo-2'-deoxyadenosines in the treatment of rheumatoid arthritis |
| US5077211A (en) * | 1988-07-06 | 1991-12-31 | Applied Genetics, Inc. | Purification and administration of dna repair enzymes |
| US6172197B1 (en) * | 1991-07-10 | 2001-01-09 | Medical Research Council | Methods for producing members of specific binding pairs |
| GB9206318D0 (en) * | 1992-03-24 | 1992-05-06 | Cambridge Antibody Tech | Binding substances |
| GB9015198D0 (en) * | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| DE69230142T2 (de) * | 1991-05-15 | 2000-03-09 | Cambridge Antibody Technology Ltd. | Verfahren zur herstellung von spezifischen bindungspaargliedern |
| US6225447B1 (en) * | 1991-05-15 | 2001-05-01 | Cambridge Antibody Technology Ltd. | Methods for producing members of specific binding pairs |
| US5565332A (en) * | 1991-09-23 | 1996-10-15 | Medical Research Council | Production of chimeric antibodies - a combinatorial approach |
| US5885793A (en) * | 1991-12-02 | 1999-03-23 | Medical Research Council | Production of anti-self antibodies from antibody segment repertoires and displayed on phage |
| US5872215A (en) * | 1991-12-02 | 1999-02-16 | Medical Research Council | Specific binding members, materials and methods |
| US5208327A (en) * | 1991-12-18 | 1993-05-04 | Ortho Pharmaceutical Corporation | Intermediates useful in a synthesis of 2-chloro-2'-deoxyadenosine |
| US5733743A (en) * | 1992-03-24 | 1998-03-31 | Cambridge Antibody Technology Limited | Methods for producing members of specific binding pairs |
| AU690528B2 (en) * | 1992-12-04 | 1998-04-30 | Medical Research Council | Multivalent and multispecific binding proteins, their manufacture and use |
| US5840299A (en) * | 1994-01-25 | 1998-11-24 | Athena Neurosciences, Inc. | Humanized antibodies against leukocyte adhesion molecule VLA-4 |
| US6001809A (en) * | 1994-07-11 | 1999-12-14 | Elan Pharmaceuticals, Inc. | Inhibitors of leukocyte adhesion |
| GB9712818D0 (en) * | 1996-07-08 | 1997-08-20 | Cambridge Antibody Tech | Labelling and selection of specific binding molecules |
| US6194395B1 (en) * | 1999-02-25 | 2001-02-27 | Orthro-Mcneil Pharmaceutical, Inc. | Cyclodextrin cladribine formulations |
| EP1485127B1 (en) * | 2002-02-25 | 2011-06-08 | Elan Pharmaceuticals, Inc. | Administration of agents for the treatment of inflammation |
| KR20060011943A (ko) * | 2003-03-28 | 2006-02-06 | 아이박스 코포레이션 | 향상된 경구 및 경점막 수송용 클라드리빈 제형 |
-
2005
- 2005-12-20 DE DE602005014570T patent/DE602005014570D1/de not_active Expired - Lifetime
- 2005-12-20 HR HR20090417T patent/HRP20090417T1/xx unknown
- 2005-12-20 PL PL05823965T patent/PL1835922T3/pl unknown
- 2005-12-20 EP EP05823965A patent/EP1835922B1/en not_active Expired - Lifetime
- 2005-12-20 AT AT05823965T patent/ATE431740T1/de active
- 2005-12-20 WO PCT/EP2005/056943 patent/WO2006067134A1/en not_active Ceased
- 2005-12-20 JP JP2007547483A patent/JP2008524310A/ja not_active Withdrawn
- 2005-12-20 AU AU2005318183A patent/AU2005318183B2/en not_active Ceased
- 2005-12-20 CA CA002590471A patent/CA2590471A1/en not_active Abandoned
- 2005-12-20 DK DK05823965T patent/DK1835922T3/da active
- 2005-12-20 SI SI200530731T patent/SI1835922T1/sl unknown
- 2005-12-20 US US11/722,487 patent/US20100129353A1/en not_active Abandoned
- 2005-12-20 ES ES05823965T patent/ES2325552T3/es not_active Expired - Lifetime
- 2005-12-20 PT PT05823965T patent/PT1835922E/pt unknown
-
2007
- 2007-06-14 IL IL183924A patent/IL183924A/en not_active IP Right Cessation
- 2007-07-13 NO NO20073635A patent/NO20073635L/no not_active Application Discontinuation
-
2009
- 2009-08-12 CY CY20091100869T patent/CY1109316T1/el unknown
Non-Patent Citations (6)
| Title |
|---|
| INTERNATIONAL JOURNAL OF CLINICAL PRACTICE, vol. 54, no. 3, JPN6011036779, 2000, pages 161 - 169, ISSN: 0001967293 * |
| NEUROLOGY, vol. No.53, No.3, JPN6011036781, 1999, pages 466 - 472, ISSN: 0001967297 * |
| PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 93, no. 4, JPN6011036773, 1996, pages 1716 - 1720, ISSN: 0001967295 * |
| 日本薬理学雑誌, vol. 第１１７巻，第２号, JPN6011036770, 2001, pages 150 - 151, ISSN: 0001967294 * |
| 神経治療学, vol. 第１８巻，第４号, JPN6011036776, 2001, pages 339 - 342, ISSN: 0001967296 * |
| 神経治療学, vol. 第２１巻，第４号, JPN6011036783, 25 July 2004 (2004-07-25), pages 387 - 392, ISSN: 0001967298 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CY1109316T1 (el) | 2014-07-02 |
| SI1835922T1 (sl) | 2009-10-31 |
| PL1835922T3 (pl) | 2009-10-30 |
| ES2325552T3 (es) | 2009-09-08 |
| NO20073635L (no) | 2007-09-24 |
| ATE431740T1 (de) | 2009-06-15 |
| PT1835922E (pt) | 2009-07-08 |
| CA2590471A1 (en) | 2006-06-29 |
| DE602005014570D1 (enExample) | 2009-07-02 |
| EP1835922A1 (en) | 2007-09-26 |
| AU2005318183A1 (en) | 2006-06-29 |
| IL183924A (en) | 2010-11-30 |
| EP1835922B1 (en) | 2009-05-20 |
| IL183924A0 (en) | 2007-10-31 |
| DK1835922T3 (da) | 2009-08-03 |
| US20100129353A1 (en) | 2010-05-27 |
| WO2006067134A1 (en) | 2006-06-29 |
| AU2005318183B2 (en) | 2011-03-31 |
| HRP20090417T1 (hr) | 2009-09-30 |
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