JP2008521837A5 - - Google Patents
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- Publication number
- JP2008521837A5 JP2008521837A5 JP2007543647A JP2007543647A JP2008521837A5 JP 2008521837 A5 JP2008521837 A5 JP 2008521837A5 JP 2007543647 A JP2007543647 A JP 2007543647A JP 2007543647 A JP2007543647 A JP 2007543647A JP 2008521837 A5 JP2008521837 A5 JP 2008521837A5
- Authority
- JP
- Japan
- Prior art keywords
- allergen
- der
- derivative
- wild
- amino acids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108010061608 Dermatophagoides pteronyssinus antigen p 2 Proteins 0.000 claims 40
- 239000013566 allergen Substances 0.000 claims 28
- 239000000203 mixture Substances 0.000 claims 15
- 238000000034 method Methods 0.000 claims 13
- 150000001413 amino acids Chemical class 0.000 claims 11
- 125000003275 alpha amino acid group Chemical group 0.000 claims 10
- 230000000694 effects Effects 0.000 claims 8
- 239000012634 fragment Substances 0.000 claims 6
- 238000002360 preparation method Methods 0.000 claims 6
- 108090000623 proteins and genes Proteins 0.000 claims 6
- 102000004169 proteins and genes Human genes 0.000 claims 6
- 229960004784 allergens Drugs 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 4
- 210000004027 cell Anatomy 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 239000000654 additive Substances 0.000 claims 2
- 230000000996 additive effect Effects 0.000 claims 2
- 229940074608 allergen extract Drugs 0.000 claims 2
- 210000004900 c-terminal fragment Anatomy 0.000 claims 2
- 210000004899 c-terminal region Anatomy 0.000 claims 2
- 210000004898 n-terminal fragment Anatomy 0.000 claims 2
- 229960005486 vaccine Drugs 0.000 claims 2
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 claims 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 230000036039 immunity Effects 0.000 claims 1
- 230000003053 immunization Effects 0.000 claims 1
- 238000002649 immunization Methods 0.000 claims 1
- 238000009169 immunotherapy Methods 0.000 claims 1
- 239000000825 pharmaceutical preparation Substances 0.000 claims 1
- 239000003755 preservative agent Substances 0.000 claims 1
- 230000002335 preservative effect Effects 0.000 claims 1
- 230000003449 preventive effect Effects 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 230000001629 suppression Effects 0.000 claims 1
- 238000003786 synthesis reaction Methods 0.000 claims 1
- 230000001131 transforming effect Effects 0.000 claims 1
- 239000012646 vaccine adjuvant Substances 0.000 claims 1
- 229940124931 vaccine adjuvant Drugs 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT0202804A AT501101B1 (de) | 2004-12-02 | 2004-12-02 | Protein-allergen-derivat |
| PCT/AT2005/000486 WO2006058359A2 (en) | 2004-12-02 | 2005-12-02 | Protein allergen derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008521837A JP2008521837A (ja) | 2008-06-26 |
| JP2008521837A5 true JP2008521837A5 (https=) | 2011-11-17 |
Family
ID=36202602
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007543647A Pending JP2008521837A (ja) | 2004-12-02 | 2005-12-02 | タンパク質アレルゲン誘導体 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20080286311A1 (https=) |
| EP (1) | EP1817330B1 (https=) |
| JP (1) | JP2008521837A (https=) |
| CN (1) | CN101068830B (https=) |
| AT (2) | AT501101B1 (https=) |
| AU (1) | AU2005312324B2 (https=) |
| CA (1) | CA2589187A1 (https=) |
| DE (1) | DE602005011667D1 (https=) |
| ES (1) | ES2319218T3 (https=) |
| PL (1) | PL1817330T3 (https=) |
| WO (1) | WO2006058359A2 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8709435B2 (en) | 2003-01-21 | 2014-04-29 | Biomay Ag | Hypallergenic mosaic antigens and methods of making same |
| ES2307381B1 (es) | 2006-04-12 | 2009-10-23 | Bial Industrial Farmaceutica S.A. | Proteinas quimericas hipoalergenicas pertenecientes a la familia de transportadoras de lipidos de parietaria judaica utiles para el tratami ento de alergias. |
| AT503690A1 (de) | 2006-06-09 | 2007-12-15 | Biomay Ag | Hypoallergene moleküle |
| EP1872792A1 (en) * | 2006-06-29 | 2008-01-02 | Biotech Tools S.A. | A method for the production of hydrolyzed allergen |
| CA2718994C (en) * | 2008-03-25 | 2017-06-13 | Bial Industrial Farmaceutica, S.A. | Hypoallergenic hybrid proteins of major group 1 and 2 mite allergens for use in the treatment of allergies |
| EP2110383A1 (en) | 2008-04-14 | 2009-10-21 | Biomay AG | Hypoallergenic variants |
| EP2295076A1 (en) | 2009-09-10 | 2011-03-16 | Biomay Ag | Hypoallergenic hybrid polypeptides for the treatment of allergy |
| JP2015514126A (ja) * | 2012-04-16 | 2015-05-18 | アルク−アベッロ エイ／エスＡｌｋ−Ａｂｅｌｌｏ Ａ／Ｓ | 非特異的アレルギー免疫療法において使用するための植物プロフィリンポリペプチド |
| CN110055340B (zh) * | 2019-04-11 | 2021-01-01 | 中国农业大学 | 一种食品中牛源成分快速检测方法及试剂盒 |
| CN113173982B (zh) * | 2021-04-14 | 2022-09-06 | 中国海洋大学 | Rap v 2蛋白相关的抗原表位肽及其应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2993967B2 (ja) * | 1987-06-17 | 1999-12-27 | インスティテュート・フォー・チャイルド・ヘルス・リサーチ | ダニアレルゲンのクローニング |
| US5433948A (en) * | 1990-02-13 | 1995-07-18 | Thomas; Wayne R. | Cloning and sequencing of allergens of dermatophagoides (house dust mite) |
| CA2066801A1 (en) * | 1991-04-26 | 1992-10-27 | Shyam S Mohapatra | Determination of dna sequences of a novel group of major grass pollen allergens and the synthesis of their correspsonding recombinant proteins |
| JPH1075783A (ja) * | 1996-09-04 | 1998-03-24 | Fumakilla Ltd | 組換えダニアレルゲン |
| JP2001231563A (ja) * | 2000-02-18 | 2001-08-28 | Asahi Breweries Ltd | 改変したダニアレルゲン（システイン変異体）及びその製造方法 |
| US7265208B2 (en) * | 2001-05-01 | 2007-09-04 | The Regents Of The University Of California | Fusion molecules and treatment of IgE-mediated allergic diseases |
| US7279295B2 (en) * | 2002-03-27 | 2007-10-09 | Phadia Ab | Allergen |
| DK1403280T3 (da) * | 2002-09-27 | 2005-11-07 | Biomay Prod & Handel | Hypoallergene allergi-vacciner baseret på timothégræspollenallergenet Phl p 7 |
| CA2503886A1 (en) * | 2002-11-01 | 2004-05-13 | Alk-Abello A/S | Recombinant protein variants |
| EP1440979B1 (en) * | 2003-01-21 | 2005-10-19 | BIOMAY Produktions- und Handels- Aktiengesellschaft | Process for the preparation of hypoallergenic mosaic proteins |
-
2004
- 2004-12-02 AT AT0202804A patent/AT501101B1/de not_active IP Right Cessation
-
2005
- 2005-12-02 PL PL05812763T patent/PL1817330T3/pl unknown
- 2005-12-02 WO PCT/AT2005/000486 patent/WO2006058359A2/en not_active Ceased
- 2005-12-02 ES ES05812763T patent/ES2319218T3/es not_active Expired - Lifetime
- 2005-12-02 EP EP05812763A patent/EP1817330B1/en not_active Revoked
- 2005-12-02 CN CN2005800416270A patent/CN101068830B/zh not_active Expired - Fee Related
- 2005-12-02 AT AT05812763T patent/ATE417060T1/de not_active IP Right Cessation
- 2005-12-02 JP JP2007543647A patent/JP2008521837A/ja active Pending
- 2005-12-02 DE DE602005011667T patent/DE602005011667D1/de not_active Expired - Lifetime
- 2005-12-02 CA CA002589187A patent/CA2589187A1/en not_active Abandoned
- 2005-12-02 US US11/720,598 patent/US20080286311A1/en not_active Abandoned
- 2005-12-02 AU AU2005312324A patent/AU2005312324B2/en not_active Ceased
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