JP2008519410A5 - - Google Patents

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JP2008519410A5
JP2008519410A5 JP2007539630A JP2007539630A JP2008519410A5 JP 2008519410 A5 JP2008519410 A5 JP 2008519410A5 JP 2007539630 A JP2007539630 A JP 2007539630A JP 2007539630 A JP2007539630 A JP 2007539630A JP 2008519410 A5 JP2008519410 A5 JP 2008519410A5
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ions
ion
ion guide
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mass
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JP4913066B2 (ja
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JP2007539630A 2004-11-04 2005-11-03 質量分析計 Expired - Lifetime JP4913066B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB0424426.5A GB0424426D0 (en) 2004-11-04 2004-11-04 Mass spectrometer
GB0424426.5 2004-11-04
US62821504P 2004-11-16 2004-11-16
US60/628,215 2004-11-16
PCT/GB2005/004238 WO2006048642A2 (en) 2004-11-04 2005-11-03 Mass spectrometer

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JP2008519410A JP2008519410A (ja) 2008-06-05
JP2008519410A5 true JP2008519410A5 (enExample) 2008-12-04
JP4913066B2 JP4913066B2 (ja) 2012-04-11

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US (8) US7829841B2 (enExample)
EP (3) EP2913840B1 (enExample)
JP (1) JP4913066B2 (enExample)
CA (2) CA2861514C (enExample)
GB (2) GB0424426D0 (enExample)
WO (1) WO2006048642A2 (enExample)

Families Citing this family (114)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020115056A1 (en) * 2000-12-26 2002-08-22 Goodlett David R. Rapid and quantitative proteome analysis and related methods
GB0305796D0 (en) 2002-07-24 2003-04-16 Micromass Ltd Method of mass spectrometry and a mass spectrometer
US7960694B2 (en) 2004-01-09 2011-06-14 Micromass Uk Limited Mass spectrometer
GB0514964D0 (en) 2005-07-21 2005-08-24 Ms Horizons Ltd Mass spectrometer devices & methods of performing mass spectrometry
GB0424426D0 (en) * 2004-11-04 2004-12-08 Micromass Ltd Mass spectrometer
GB0426520D0 (en) * 2004-12-02 2005-01-05 Micromass Ltd Mass spectrometer
ATE512458T1 (de) 2004-12-07 2011-06-15 Micromass Ltd Massenspektrometer
GB0426900D0 (en) * 2004-12-08 2005-01-12 Micromass Ltd Mass spectrometer
GB0503010D0 (en) * 2005-02-14 2005-03-16 Micromass Ltd Mass spectrometer
US8440968B2 (en) * 2005-02-14 2013-05-14 Micromass Uk Limited Ion-mobility analyser
US7484774B2 (en) 2005-05-03 2009-02-03 Ti Group Automotive Systems, Llc Redundant latch/verifier for a quick connector
JP4843250B2 (ja) * 2005-05-13 2011-12-21 株式会社日立ハイテクノロジーズ 質量分析を用いた物質の同定方法
US7482582B2 (en) * 2005-05-27 2009-01-27 Ionwerks, Inc. Multi-beam ion mobility time-of-flight mass spectrometry with multi-channel data recording
DE102005025499B4 (de) * 2005-06-03 2007-09-27 Bruker Daltonik Gmbh Massenspektrometrische Gemischanalyse
GB2432712B (en) * 2005-11-23 2007-12-27 Micromass Ltd Mass spectrometer
US7700913B2 (en) 2006-03-03 2010-04-20 Ionsense, Inc. Sampling system for use with surface ionization spectroscopy
US8026477B2 (en) 2006-03-03 2011-09-27 Ionsense, Inc. Sampling system for use with surface ionization spectroscopy
US7420161B2 (en) * 2006-03-09 2008-09-02 Thermo Finnigan Llc Branched radio frequency multipole
US7453059B2 (en) * 2006-03-10 2008-11-18 Varian Semiconductor Equipment Associates, Inc. Technique for monitoring and controlling a plasma process
US7476849B2 (en) * 2006-03-10 2009-01-13 Varian Semiconductor Equipment Associates, Inc. Technique for monitoring and controlling a plasma process
US7497480B2 (en) 2006-04-07 2009-03-03 Ti Group Automotive Systems, Llc Hybrid quick connector
GB0608470D0 (en) * 2006-04-28 2006-06-07 Micromass Ltd Mass spectrometer
JP2009539114A (ja) 2006-05-26 2009-11-12 イオンセンス インコーポレイテッド 表面イオン化技術で用いるための固体を保持する器具
GB0612503D0 (en) 2006-06-23 2006-08-02 Micromass Ltd Mass spectrometer
GB0624740D0 (en) * 2006-12-12 2007-01-17 Micromass Ltd Mass spectrometer
GB0624993D0 (en) * 2006-12-14 2007-01-24 Micromass Ltd Mass spectrometer
CA2672526C (en) * 2006-12-14 2016-08-23 Micromass Uk Limited Mass spectrometer
GB0701476D0 (en) * 2007-01-25 2007-03-07 Micromass Ltd Mass spectrometer
GB0705730D0 (en) 2007-03-26 2007-05-02 Micromass Ltd Mass spectrometer
US8507850B2 (en) 2007-05-31 2013-08-13 Perkinelmer Health Sciences, Inc. Multipole ion guide interface for reduced background noise in mass spectrometry
US8901487B2 (en) 2007-07-20 2014-12-02 George Washington University Subcellular analysis by laser ablation electrospray ionization mass spectrometry
US8067730B2 (en) 2007-07-20 2011-11-29 The George Washington University Laser ablation electrospray ionization (LAESI) for atmospheric pressure, In vivo, and imaging mass spectrometry
US7964843B2 (en) 2008-07-18 2011-06-21 The George Washington University Three-dimensional molecular imaging by infrared laser ablation electrospray ionization mass spectrometry
GB0714301D0 (en) * 2007-07-21 2007-08-29 Ionoptika Ltd Secondary ion mass spectrometry and secondary neutral mass spectrometry using a multiple-plate buncher
GB0723183D0 (en) * 2007-11-23 2008-01-09 Micromass Ltd Mass spectrometer
GB0801309D0 (en) * 2008-01-24 2008-03-05 Micromass Ltd Mass spectrometer
US7675031B2 (en) * 2008-05-29 2010-03-09 Thermo Finnigan Llc Auxiliary drag field electrodes
US8026475B2 (en) * 2008-08-19 2011-09-27 Thermo Finnigan Llc Method and apparatus for a dual gate for a mass spectrometer
US8207497B2 (en) 2009-05-08 2012-06-26 Ionsense, Inc. Sampling of confined spaces
US8716655B2 (en) * 2009-07-02 2014-05-06 Tricorntech Corporation Integrated ion separation spectrometer
WO2011017409A1 (en) * 2009-08-05 2011-02-10 Indiana University Research And Technology Corporation Apparatus for determining masses at high pressure
US8604419B2 (en) * 2010-02-04 2013-12-10 Thermo Fisher Scientific (Bremen) Gmbh Dual ion trapping for ion/ion reactions in a linear RF multipole trap with an additional DC gradient
US8552917B2 (en) * 2010-04-28 2013-10-08 The Boeing Company Wide angle multibeams
GB2476844B (en) * 2010-05-24 2011-12-07 Fasmatech Science And Technology Llc Improvements relating to the control of ions
GB201019337D0 (en) * 2010-11-16 2010-12-29 Micromass Ltd Controlling hydrogen-deuterium exchange on a spectrum by spectrum basis
GB2486484B (en) * 2010-12-17 2013-02-20 Thermo Fisher Scient Bremen Ion detection system and method
US8822949B2 (en) 2011-02-05 2014-09-02 Ionsense Inc. Apparatus and method for thermal assisted desorption ionization systems
GB201104220D0 (en) * 2011-03-14 2011-04-27 Micromass Ltd Ion guide with orthogonal sampling
GB201104292D0 (en) 2011-03-15 2011-04-27 Micromass Ltd M/z targets attenuation on time of flight instruments
US8901488B1 (en) 2011-04-18 2014-12-02 Ionsense, Inc. Robust, rapid, secure sample manipulation before during and after ionization for a spectroscopy system
US8829426B2 (en) 2011-07-14 2014-09-09 The George Washington University Plume collimation for laser ablation electrospray ionization mass spectrometry
DE112012004563T5 (de) * 2011-11-02 2014-08-21 Leco Corporation Ionenmobilitätsspektrometer
WO2013137883A1 (en) * 2012-03-15 2013-09-19 Shimadzu Corporation An ion-mobility spectrometer including a decelarating ion gate
GB201205009D0 (en) * 2012-03-22 2012-05-09 Micromass Ltd Multi-dimensional survey scans for improved data dependent acquisitions (DDA)
CN103367090B (zh) * 2012-03-30 2016-12-21 岛津分析技术研发（上海）有限公司 离子分析器以及离子分析方法
DE102012008259B4 (de) * 2012-04-25 2014-06-26 Bruker Daltonik Gmbh Ionenerzeugung in Massenspektrometern durch Clusterbeschuss
US8791409B2 (en) * 2012-07-27 2014-07-29 Thermo Fisher Scientific (Bremen) Gmbh Method and analyser for analysing ions having a high mass-to-charge ratio
US10145818B2 (en) 2012-10-22 2018-12-04 President And Fellows Of Harvard College Accurate and interference-free multiplexed quantitative proteomics using mass spectrometry
US8969797B2 (en) * 2012-10-28 2015-03-03 Shimadzu Corporation MS/MS type mass spectrometer
GB201304039D0 (en) * 2013-03-06 2013-04-17 Micromass Ltd Time shift improved IMS digitisation
GB201304037D0 (en) * 2013-03-06 2013-04-17 Micromass Ltd Optimised ion mobility separation timescales for targeted ions
EP2965342B1 (en) 2013-03-06 2020-08-05 Micromass UK Limited Time shift for improved digitisation of ion analysis
CA2903623C (en) 2013-03-06 2021-04-20 Micromass Uk Limited Optimised ion mobility separation timescales for targeted ions
GB2517670B (en) * 2013-03-15 2020-04-29 Smiths Detection Watford Ltd Ion modification
US9455132B2 (en) * 2013-05-30 2016-09-27 Agilent Technologies, Inc. Ion mobility spectrometry-mass spectrometry (IMS-MS) with improved ion transmission and IMS resolution
GB201319958D0 (en) * 2013-11-12 2013-12-25 Micromass Ltd Method of correlating precursor and fragment ions
EP3069373B1 (en) * 2013-11-12 2024-03-13 Micromass UK Limited Method of correlating precursor and fragment ions
GB201321246D0 (en) * 2013-12-02 2014-01-15 Micromass Ltd Capillary electrophoresis - mass spectrometry linked scanning
US9772304B2 (en) 2013-12-02 2017-09-26 Micromass Uk Limited Method of charge state selection
WO2015136266A1 (en) * 2014-03-10 2015-09-17 Micromass Uk Limited Method for separating ions according to a physicochemical property
DE112015002567B4 (de) * 2014-05-30 2023-09-07 Micromass Uk Limited Hybridmassenspektrometer
WO2015185941A1 (en) * 2014-06-06 2015-12-10 Micromass Uk Limited Mobility selective attenuation
DE112015002737B4 (de) * 2014-06-10 2020-04-23 Micromass Uk Limited Segmentierter linearer ionenmobilitätsspektrometertreiber
US9337007B2 (en) 2014-06-15 2016-05-10 Ionsense, Inc. Apparatus and method for generating chemical signatures using differential desorption
US9972480B2 (en) * 2015-01-30 2018-05-15 Agilent Technologies, Inc. Pulsed ion guides for mass spectrometers and related methods
US9891194B2 (en) * 2015-11-03 2018-02-13 Bruker Daltonik Gmbh Acquisition of fragment ion mass spectra of ions separated by their mobility
GB201608653D0 (en) * 2016-05-17 2016-06-29 Micromass Ltd Ion mobility seperator
WO2017210427A1 (en) 2016-06-03 2017-12-07 President And Fellows Of Harvard College Techniques for high throughput targeted proteomic analysis and related systems and methods
JP6750687B2 (ja) * 2016-12-15 2020-09-02 株式会社島津製作所 質量分析装置
CN110100299A (zh) * 2016-12-28 2019-08-06 拉皮斯坎系统股份有限公司 具有用于离子捕获和离子压缩的势阱的电离室
US10241079B2 (en) * 2017-05-24 2019-03-26 Bruker Daltonik Gmbh Mass spectrometer with tandem ion mobility analyzers
US12180581B2 (en) 2017-09-18 2024-12-31 Waters Technologies Corporation Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes
US11709155B2 (en) 2017-09-18 2023-07-25 Waters Technologies Corporation Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes
US11709156B2 (en) 2017-09-18 2023-07-25 Waters Technologies Corporation Use of vapor deposition coated flow paths for improved analytical analysis
US12181452B2 (en) 2017-09-18 2024-12-31 Waters Technologies Corporation Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes
US10741375B2 (en) 2018-05-14 2020-08-11 MOBILion Systems, Inc. Coupling of ion mobility spectrometer with mass spectrometer
US11373849B2 (en) 2018-05-31 2022-06-28 Micromass Uk Limited Mass spectrometer having fragmentation region
GB201808932D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Bench-top time of flight mass spectrometer
GB201808893D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Bench-top time of flight mass spectrometer
GB201808894D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Mass spectrometer
GB201808949D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Bench-top time of flight mass spectrometer
GB201808936D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Bench-top time of flight mass spectrometer
GB201808892D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Mass spectrometer
GB201808890D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Bench-top time of flight mass spectrometer
GB201808912D0 (en) 2018-05-31 2018-07-18 Micromass Ltd Bench-top time of flight mass spectrometer
CN112154531B (zh) 2018-05-31 2024-05-17 英国质谱公司 质谱仪
US12089932B2 (en) 2018-06-05 2024-09-17 Trace Matters Scientific Llc Apparatus, system, and method for transferring ions
US10840077B2 (en) 2018-06-05 2020-11-17 Trace Matters Scientific Llc Reconfigureable sequentially-packed ion (SPION) transfer device
EP3864684B1 (en) 2018-10-09 2025-06-25 DH Technologies Development Pte. Ltd. Electron beam throttling for electron capture dissociation
US12176196B2 (en) * 2019-02-15 2024-12-24 Ohio State Innovation Foundation Surface-induced dissociation devices and methods
EP3972726A4 (en) 2019-05-21 2023-05-10 Mobilion Systems, Inc. VOLTAGE CONTROL FOR ION MOBILITY SEPARATION
WO2020248757A1 (en) 2019-06-14 2020-12-17 Shanghai Polaris Biology Co., Ltd. Systems and methods for single particle analysis
US11543384B2 (en) 2019-11-22 2023-01-03 MOBILion Systems, Inc. Mobility based filtering of ions
US11918936B2 (en) 2020-01-17 2024-03-05 Waters Technologies Corporation Performance and dynamic range for oligonucleotide bioanalysis through reduction of non specific binding
WO2021207235A1 (en) 2020-04-06 2021-10-14 MOBILion Systems, Inc. Systems and methods for two-dimensional mobility based filtering of ions
US12163920B2 (en) 2020-04-06 2024-12-10 MOBILion Systems, Inc. Systems and methods for two-dimensional mobility based filtering of ions
US11953466B2 (en) 2020-05-22 2024-04-09 MOBILion Systems, Inc. Methods and apparatus for trapping and accumulation of ions
EP3916755A1 (en) * 2020-05-26 2021-12-01 Thermo Finnigan LLC Methods and apparatus for high speed mass spectrometry
WO2021247820A1 (en) 2020-06-05 2021-12-09 MOBILion Systems, Inc. Apparatus and methods for ion manipulation having improved duty cycle
CN116391122A (zh) 2020-09-24 2023-07-04 沃特世科技公司 用于反应性分子分离的色谱硬件改进
US20230008420A1 (en) * 2021-06-30 2023-01-12 MOBILion Systems, Inc. Ion Funnels Having Improved Pressure Distribution and Flow Characteristics
US20230052193A1 (en) * 2021-06-30 2023-02-16 MOBILion Systems, Inc. Ions Funnels Having Improved Pressure Distribution and Flow Characteristics
GB202204106D0 (en) * 2022-03-23 2022-05-04 Micromass Ltd Mass spectrometer having high duty cycle
CN117423603B (zh) * 2023-09-26 2025-01-24 山东英盛生物技术有限公司 基于原位质谱技术的样品检测装置及工作方法

Family Cites Families (126)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3668383A (en) 1969-01-09 1972-06-06 Franklin Gno Corp Apparatus and methods for separating, detecting, and measuring trace gases
US3621240A (en) 1969-05-27 1971-11-16 Franklin Gro Corp Apparatus and methods for detecting and identifying trace gases
US3626178A (en) 1970-02-20 1971-12-07 Franklin Gno Corp Gas or liquid chromatograph with detector employing ion-molecule reactions and ion drift
US3626179A (en) 1970-04-03 1971-12-07 Franklin Gno Corp High temperature method and apparatus for analyzing gaseous samples
US3812355A (en) 1971-12-09 1974-05-21 Gno F Corp Apparatus and methods for measuring ion mass as a function of mobility
DE2205713A1 (de) 1972-02-08 1973-08-23 Viktor Dr Ing Winkler Doppel-ionenstrahlverfahren fuer quantitative (absolute) massenspektrometrische messungen
US3845301A (en) 1972-05-10 1974-10-29 Franklin Gno Corp Apparatus and methods employing ion analysis apparatus with enhanced gas flow
US3902064A (en) 1974-07-12 1975-08-26 Robert A Young Ion mobility mass spectrometer
US4234791A (en) 1978-11-13 1980-11-18 Research Corporation Tandem quadrupole mass spectrometer for selected ion fragmentation studies and low energy collision induced dissociator therefor
US4261698A (en) 1980-01-23 1981-04-14 International Business Machines Corporation Trace oxygen detector
US4855595A (en) 1986-07-03 1989-08-08 Allied-Signal Inc. Electric field control in ion mobility spectrometry
US4823368A (en) 1987-06-30 1989-04-18 Rikagaku Kenkyujyo Open counter for low energy electron detection with suppressed background noise
WO1989006044A1 (en) 1987-12-24 1989-06-29 Unisearch Limited Mass spectrometer
GB2217103B (en) 1988-04-06 1992-09-23 Graseby Ionics Ltd Ion mobility detector
US4987767A (en) 1989-06-09 1991-01-29 Research Corporation Technologies, Inc. Exposive detection screening system
US5073713A (en) 1990-05-29 1991-12-17 Battelle Memorial Institute Detection method for dissociation of multiple-charged ions
US5070240B1 (en) 1990-08-29 1996-09-10 Univ Brigham Young Apparatus and methods for trace component analysis
US5140158A (en) 1990-10-05 1992-08-18 The United States Of America As Represented By The United States Department Of Energy Method for discriminative particle selection
US5210412A (en) 1991-01-31 1993-05-11 Wayne State University Method for analyzing an organic sample
JPH08507926A (ja) 1993-03-19 1996-08-27 シーケノム・インコーポレーテツド エキソヌクレアーゼ分解を介した質量分析法によるｄｎａ配列決定
DK0748249T3 (da) 1994-02-28 2009-11-09 Analytica Of Branford Inc Multipolionguide for massespektrometri
US5689111A (en) 1995-08-10 1997-11-18 Analytica Of Branford, Inc. Ion storage time-of-flight mass spectrometer
US5420424A (en) 1994-04-29 1995-05-30 Mine Safety Appliances Company Ion mobility spectrometer
US5504326A (en) 1994-10-24 1996-04-02 Indiana University Foundation Spatial-velocity correlation focusing in time-of-flight mass spectrometry
DE19511333C1 (de) 1995-03-28 1996-08-08 Bruker Franzen Analytik Gmbh Verfahren und Vorrichtung für orthogonalen Einschuß von Ionen in ein Flugzeit-Massenspektrometer
US5569917A (en) 1995-05-19 1996-10-29 Varian Associates, Inc. Apparatus for and method of forming a parallel ion beam
JPH095298A (ja) 1995-06-06 1997-01-10 Varian Assoc Inc 四重極イオントラップ内の選択イオン種を検出する方法
US5552600A (en) 1995-06-07 1996-09-03 Barringer Research Limited Pressure stabilized ion mobility spectrometer
WO1997007530A1 (en) 1995-08-11 1997-02-27 Mds Health Group Limited Spectrometer with axial field
US5811059A (en) 1995-10-16 1998-09-22 The United States Of America As Represented By The Secretary Of The Army Automated, on-demand ion mobility spectrometry analysis of gas chromatograph effluents
PT1007959E (pt) 1995-12-23 2006-08-31 Univ Belfast Sistema de entrada de gas
DE19628179C2 (de) 1996-07-12 1998-04-23 Bruker Franzen Analytik Gmbh Vorrichtung und Verfahren zum Einschuß von Ionen in eine Ionenfalle
WO1998042006A1 (en) 1997-03-14 1998-09-24 George Washington University A device for continuous isotope ratio monitoring following fluorine based chemical reactions
WO1998040520A1 (en) 1997-03-14 1998-09-17 Hybridon, Inc. Method for sequencing of modified nucleic acids using electrospray ionization-fourier transform mass spectrometry
US6960761B2 (en) 1997-06-02 2005-11-01 Advanced Research & Technology Institute Instrument for separating ions in time as functions of preselected ion mobility and ion mass
US6323482B1 (en) * 1997-06-02 2001-11-27 Advanced Research And Technology Institute, Inc. Ion mobility and mass spectrometer
US5905258A (en) * 1997-06-02 1999-05-18 Advanced Research & Techology Institute Hybrid ion mobility and mass spectrometer
US6498342B1 (en) 1997-06-02 2002-12-24 Advanced Research & Technology Institute Ion separation instrument
GB9717926D0 (en) 1997-08-22 1997-10-29 Micromass Ltd Methods and apparatus for tandem mass spectrometry
US5789745A (en) 1997-10-28 1998-08-04 Sandia Corporation Ion mobility spectrometer using frequency-domain separation
EP1050065A4 (en) 1998-01-23 2004-03-31 Analytica Of Branford Inc SURFACES MASS
US6124592A (en) 1998-03-18 2000-09-26 Technispan Llc Ion mobility storage trap and method
US6107628A (en) * 1998-06-03 2000-08-22 Battelle Memorial Institute Method and apparatus for directing ions and other charged particles generated at near atmospheric pressures into a region under vacuum
US6504149B2 (en) 1998-08-05 2003-01-07 National Research Council Canada Apparatus and method for desolvating and focussing ions for introduction into a mass spectrometer
US6621077B1 (en) 1998-08-05 2003-09-16 National Research Council Canada Apparatus and method for atmospheric pressure-3-dimensional ion trapping
WO2000008456A1 (en) 1998-08-05 2000-02-17 National Research Council Canada Method for separation and enrichment of isotopes in gaseous phase
US6713758B2 (en) 1998-08-05 2004-03-30 National Research Council Of Canada Spherical side-to-side FAIMS
CA2260572A1 (en) 1998-08-05 2000-02-05 Randy W. Purves Apparatus and method for atmospheric pressure 3-dimensional ion trapping
WO2000017908A2 (en) 1998-09-23 2000-03-30 Wisconsin Alumni Research Foundation Charge reduction in electrospray mass spectrometry
US6507019B2 (en) 1999-05-21 2003-01-14 Mds Inc. MS/MS scan methods for a quadrupole/time of flight tandem mass spectrometer
US6495823B1 (en) 1999-07-21 2002-12-17 The Charles Stark Draper Laboratory, Inc. Micromachined field asymmetric ion mobility filter and detection system
US6690004B2 (en) 1999-07-21 2004-02-10 The Charles Stark Draper Laboratory, Inc. Method and apparatus for electrospray-augmented high field asymmetric ion mobility spectrometry
US6815668B2 (en) 1999-07-21 2004-11-09 The Charles Stark Draper Laboratory, Inc. Method and apparatus for chromatography-high field asymmetric waveform ion mobility spectrometry
US6512224B1 (en) 1999-07-21 2003-01-28 The Charles Stark Draper Laboratory, Inc. Longitudinal field driven field asymmetric ion mobility filter and detection system
US7164122B2 (en) 2000-02-29 2007-01-16 Ionwerks, Inc. Ion mobility spectrometer
AU2001247243A1 (en) 2000-02-29 2001-09-12 Ionwerks, Inc. Improved mobility spectrometer
EP1266209A2 (en) 2000-03-14 2002-12-18 National Research Council of Canada Tandem high field asymmetric waveform ion mobility spectrometry (faims)/ion mobility spectrometry
US6806466B2 (en) 2000-03-14 2004-10-19 National Research Council Canada Parallel plate geometry FAIMS apparatus and method
AU3907401A (en) 2000-03-14 2001-09-24 Ca Nat Research Council Apparatus and method for trandem icp/faims/ms
US6545268B1 (en) 2000-04-10 2003-04-08 Perseptive Biosystems Preparation of ion pulse for time-of-flight and for tandem time-of-flight mass analysis
AU2001286665A1 (en) 2000-08-24 2002-03-04 Newton Scientific, Inc. Sample introduction interface for analytical processing
US6744043B2 (en) * 2000-12-08 2004-06-01 Mds Inc. Ion mobilty spectrometer incorporating an ion guide in combination with an MS device
US6683301B2 (en) 2001-01-29 2004-01-27 Analytica Of Branford, Inc. Charged particle trapping in near-surface potential wells
US6627883B2 (en) * 2001-03-02 2003-09-30 Bruker Daltonics Inc. Apparatus and method for analyzing samples in a dual ion trap mass spectrometer
WO2002080223A1 (en) 2001-03-29 2002-10-10 Wisconsin Alumni Research Foundation Piezoelectric charged droplet source
US7041967B2 (en) * 2001-05-25 2006-05-09 Mds Inc. Method of mass spectrometry, to enhance separation of ions with different charges
WO2002097857A1 (en) * 2001-05-25 2002-12-05 Analytica Of Branford, Inc. Atmospheric and vacuum pressure maldi ion source
US7586088B2 (en) 2001-06-21 2009-09-08 Micromass Uk Limited Mass spectrometer and method of mass spectrometry
US6762404B2 (en) 2001-06-25 2004-07-13 Micromass Uk Limited Mass spectrometer
US20030000921A1 (en) * 2001-06-29 2003-01-02 Ted Liang Mask repair with electron beam-induced chemical etching
US7091481B2 (en) 2001-08-08 2006-08-15 Sionex Corporation Method and apparatus for plasma generation
US7274015B2 (en) 2001-08-08 2007-09-25 Sionex Corporation Capacitive discharge plasma ion source
US7635841B2 (en) * 2001-12-12 2009-12-22 Micromass Uk Limited Method of mass spectrometry
WO2003067244A2 (en) 2002-02-08 2003-08-14 Ionalytics Corporation Faims with non-destructive detection of selectively transmitted ions
US6630662B1 (en) 2002-04-24 2003-10-07 Mds Inc. Setup for mobility separation of ions implementing an ion guide with an axial field and counterflow of gas
GB2390478B (en) 2002-05-17 2004-06-02 Micromass Ltd Mass spectrometer
US6906319B2 (en) 2002-05-17 2005-06-14 Micromass Uk Limited Mass spectrometer
US6872939B2 (en) * 2002-05-17 2005-03-29 Micromass Uk Limited Mass spectrometer
US6794641B2 (en) * 2002-05-30 2004-09-21 Micromass Uk Limited Mass spectrometer
EP1505632B1 (en) * 2002-05-30 2011-01-12 Micromass UK Limited Mass spectrometer
US7095013B2 (en) 2002-05-30 2006-08-22 Micromass Uk Limited Mass spectrometer
US6891157B2 (en) 2002-05-31 2005-05-10 Micromass Uk Limited Mass spectrometer
US6791078B2 (en) 2002-06-27 2004-09-14 Micromass Uk Limited Mass spectrometer
GB0305796D0 (en) * 2002-07-24 2003-04-16 Micromass Ltd Method of mass spectrometry and a mass spectrometer
GB2394356B (en) * 2002-08-05 2005-02-16 Micromass Ltd Mass spectrometer
US7071467B2 (en) * 2002-08-05 2006-07-04 Micromass Uk Limited Mass spectrometer
US7417225B2 (en) 2002-09-25 2008-08-26 Thermo Finnigan Llc Apparatus and method for adjustment of ion separation resolution in FAIMS
CA2502445C (en) 2002-09-25 2011-08-23 Ionalytics Corporation Faims apparatus and method for separating ions
US7223971B2 (en) 2004-03-03 2007-05-29 Thermo Finnigan Llc Method and apparatus for selecting inlets of a multiple inlet FAIMS
AU2003298597A1 (en) 2002-10-12 2004-05-25 Sionex Corporation NOx MONITOR USING DIFFERENTIAL MOBILITY SPECTROMETRY
US6642516B1 (en) 2002-12-18 2003-11-04 Agilent Technologies, Inc. Apparatus and method of laser dissociation for mass spectrometry
US6906320B2 (en) 2003-04-02 2005-06-14 Merck & Co., Inc. Mass spectrometry data analysis techniques
US7459693B2 (en) * 2003-04-04 2008-12-02 Bruker Daltonics, Inc. Ion guide for mass spectrometers
US20040195503A1 (en) * 2003-04-04 2004-10-07 Taeman Kim Ion guide for mass spectrometers
GB0313016D0 (en) 2003-06-06 2003-07-09 Ms Horizons Ltd Ion extraction
US6992283B2 (en) * 2003-06-06 2006-01-31 Micromass Uk Limited Mass spectrometer
US7075070B2 (en) 2003-06-20 2006-07-11 Brigham Young University Single device for ion mobility and ion trap mass spectrometry
US7385187B2 (en) * 2003-06-21 2008-06-10 Leco Corporation Multi-reflecting time-of-flight mass spectrometer and method of use
US7093623B2 (en) 2003-06-27 2006-08-22 The Gillette Company Methods of providing refueling for fuel cell-powered devices
WO2005050159A2 (en) 2003-10-14 2005-06-02 Washington State University Research Foundation Ion mobility spectrometry method and apparatus
US6967325B2 (en) * 2003-10-30 2005-11-22 Battelle Memorial Institute High performance ion mobility spectrometry using hourglass electrodynamic funnel and internal ion funnel
US6818890B1 (en) * 2003-10-30 2004-11-16 Battelle Memorial Institute High performance ion mobility spectrometry using hourglass electrodynamic funnel and internal ion funnel
GB2409927B (en) 2004-01-09 2006-09-27 Microsaic Systems Ltd Micro-engineered electron multipliers
CA2551991A1 (en) 2004-01-13 2005-07-28 Sionex Corporation Methods and apparatus for enhanced sample identification based on combined analytical techniques
US7135674B2 (en) 2004-01-22 2006-11-14 Thermo Finnigan Llc Method and apparatus for FAIMS with a laser-based ionization source
US7112788B2 (en) 2004-01-22 2006-09-26 Ionalytics Corporation Apparatus and method for controllably affecting the temperature of FAIMS components
GB0408751D0 (en) 2004-04-20 2004-05-26 Micromass Ltd Mass spectrometer
GB0420408D0 (en) 2004-09-14 2004-10-20 Micromass Ltd Mass spectrometer
JP4513488B2 (ja) 2004-10-06 2010-07-28 株式会社日立製作所 イオンモビリティー分析装置及びイオンモビリティー分析方法
GB0424426D0 (en) * 2004-11-04 2004-12-08 Micromass Ltd Mass spectrometer
GB0426520D0 (en) 2004-12-02 2005-01-05 Micromass Ltd Mass spectrometer
GB0503010D0 (en) 2005-02-14 2005-03-16 Micromass Ltd Mass spectrometer
US8440968B2 (en) 2005-02-14 2013-05-14 Micromass Uk Limited Ion-mobility analyser
GB0506665D0 (en) 2005-04-01 2005-05-11 Micromass Ltd Mass spectrometer
GB0522933D0 (en) 2005-11-10 2005-12-21 Micromass Ltd Mass spectrometer
WO2007057623A1 (en) 2005-11-16 2007-05-24 Shimadzu Corporation Mass spectrometer
KR100716495B1 (ko) 2005-11-23 2007-05-10 창원대학교 산학협력단 기체전자증폭기를 이용한 디지털 영상 광 검출장치
JP5022611B2 (ja) 2006-03-02 2012-09-12 独立行政法人理化学研究所 ガス電子増幅フォイルの製造方法
GB0613900D0 (en) 2006-07-13 2006-08-23 Micromass Ltd Mass spectrometer
GB2457556B (en) 2007-02-26 2010-02-17 Micromass Ltd Helical ion guide
GB2457769B (en) 2007-09-14 2010-07-14 Micromass Ltd Method of ion mobility separation
GB0723487D0 (en) 2007-11-30 2008-01-09 Micromass Ltd Mass spectrometer
GB0801309D0 (en) 2008-01-24 2008-03-05 Micromass Ltd Mass spectrometer
GB0815397D0 (en) 2008-08-22 2008-10-01 Micromass Ltd Mass spectrometer
GB201111568D0 (en) * 2011-07-06 2011-08-24 Micromass Ltd Apparatus and method of mass spectrometry
EP3945314B1 (en) * 2020-07-31 2022-10-26 Bruker Daltonics GmbH & Co. KG Method and apparatus for data independent combined ion mobility and mass spectroscopy analysis

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