JP2008519047A5 - - Google Patents

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Publication number
JP2008519047A5
JP2008519047A5 JP2007540086A JP2007540086A JP2008519047A5 JP 2008519047 A5 JP2008519047 A5 JP 2008519047A5 JP 2007540086 A JP2007540086 A JP 2007540086A JP 2007540086 A JP2007540086 A JP 2007540086A JP 2008519047 A5 JP2008519047 A5 JP 2008519047A5
Authority
JP
Japan
Prior art keywords
cancer
bendamustine
formulation
refractory
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2007540086A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008519047A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2005/040068 external-priority patent/WO2006065392A2/fr
Publication of JP2008519047A publication Critical patent/JP2008519047A/ja
Publication of JP2008519047A5 publication Critical patent/JP2008519047A5/ja
Pending legal-status Critical Current

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JP2007540086A 2004-11-05 2005-11-04 癌処置 Pending JP2008519047A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US62519304P 2004-11-05 2004-11-05
US66022605P 2005-03-10 2005-03-10
PCT/US2005/040068 WO2006065392A2 (fr) 2004-11-05 2005-11-04 Traitements anti-cancereux

Publications (2)

Publication Number Publication Date
JP2008519047A JP2008519047A (ja) 2008-06-05
JP2008519047A5 true JP2008519047A5 (fr) 2008-12-18

Family

ID=36588320

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007540086A Pending JP2008519047A (ja) 2004-11-05 2005-11-04 癌処置

Country Status (12)

Country Link
US (2) US20060128777A1 (fr)
EP (1) EP1814544A4 (fr)
JP (1) JP2008519047A (fr)
CN (1) CN101933923A (fr)
AR (1) AR054094A1 (fr)
AU (1) AU2005317047A1 (fr)
CA (1) CA2585659A1 (fr)
CL (1) CL2009001721A1 (fr)
MX (1) MX2007005361A (fr)
NO (1) NO20072654L (fr)
TW (1) TW200621240A (fr)
WO (1) WO2006065392A2 (fr)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ542445A (en) 2003-04-07 2008-03-28 Pharmacyclics Inc Hydroxamates as therapeutic agents
US8436190B2 (en) 2005-01-14 2013-05-07 Cephalon, Inc. Bendamustine pharmaceutical compositions
US20090075967A1 (en) * 2007-09-15 2009-03-19 Protia, Llc Deuterium-enriched ceftriaxone
US20090082416A1 (en) * 2007-09-25 2009-03-26 Protia, Llc Deuterium-enriched bendamustine
AR072777A1 (es) 2008-03-26 2010-09-22 Cephalon Inc Formas solidas de clorhidrato de bendamustina
CN102056607B (zh) * 2008-04-17 2014-07-30 约翰·霍普金斯大学 On01910.na促进在抗药性肿瘤中化学治疗剂的活性
WO2010036702A1 (fr) * 2008-09-25 2010-04-01 Cephalon, Inc. Formulations liquides de bendamustine
UA107186C2 (xx) * 2008-12-03 2014-12-10 Тверді форми дозування бендамустину
DK2367542T3 (da) * 2008-12-03 2014-03-10 Astellas Deutschland Gmbh Orale doseringsformer af bendamustin
JP5654498B2 (ja) * 2009-02-25 2015-01-14 スプラテック ファーマ インコーポレイテッド ベンダムスチン環状多糖組成物
US8603521B2 (en) 2009-04-17 2013-12-10 Pharmacyclics, Inc. Formulations of histone deacetylase inhibitor and uses thereof
EP2424506A1 (fr) * 2009-04-28 2012-03-07 Cephalon, Inc. Formulations orales de bendamustine
WO2010144675A1 (fr) 2009-06-10 2010-12-16 Plus Chemicals Sa Polymorphes du chlorhydrate de bendamustine et leurs procédés de préparation
US8389558B2 (en) * 2009-07-20 2013-03-05 Supratek Pharma Inc. Bendamustine amphiphilic anionic compositions
HUE031208T2 (hu) 2010-01-28 2017-07-28 Eagle Pharmaceuticals Inc Bendamusztin kiszerelései
JO3659B1 (ar) 2010-06-02 2020-08-27 Astellas Deutschland Gmbh أشكال جرعات بينداموستين عن طريق الفم وإستخداماته العلاجية
MX2012013872A (es) * 2010-06-02 2013-04-03 Astellas Deutschland Gmbh Formas de dosificacion oral de bendamustina.
US8383663B2 (en) 2010-07-19 2013-02-26 Supratek Pharma Inc. Bendamustine anionic-catioinic cyclopolysaccharide compositions
TW201306842A (zh) * 2011-06-15 2013-02-16 Exelixis Inc 使用ｐｉ３ｋ／ｍｔｏｒ吡啶並嘧啶酮抑制劑及苯達莫司汀及／或利妥昔單抗治療惡性血液疾病之組合療法
SG10201606785UA (en) 2011-08-16 2016-10-28 Morphosys Ag Combination therapy with an anti - cd19 antibody and a nitrogen mustard
CN103917231B (zh) * 2011-09-13 2016-09-28 药品循环有限责任公司 组蛋白脱乙酰酶抑制剂与苯达莫司汀的联合制剂及其用途
ES2613838T3 (es) 2011-09-26 2017-05-26 Fresenius Kabi Oncology Ltd Un procedimiento mejorado para la preparación de hidrocloruro de bendamustina
RS65177B1 (sr) 2012-03-20 2024-03-29 Eagle Pharmaceuticals Inc Formulacije bendamustina
RS64137B1 (sr) 2012-03-20 2023-05-31 Eagle Pharmaceuticals Inc Tečne kompozicije bendamustina za upotrebu u postupku lečenja stanja koja reaguju na bendamustin kod pacijenata kojima su potrebne smanjene zapremine za primenu
US8927516B2 (en) * 2012-03-29 2015-01-06 Institute For Cancer Research Combination of DNA repair inhibition with bendamustine or gemcitabine in the treatment of cancer
US10220051B2 (en) 2012-03-29 2019-03-05 Institute For Cancer Research Combination of DNA repair inhibition with bendamustine or gemcitabine in the treatment of cancer
TWI649081B (zh) 2013-08-02 2019-02-01 製藥公司 治療固態腫瘤之方法
US20150087681A1 (en) * 2013-09-25 2015-03-26 Pranav Patel Bendamustine HCL Stable Lyophilized Formulations
CA2925922C (fr) 2013-09-30 2023-03-21 Institute For Cancer Research D/B/A The Research Institute Of Fox Chase Cancer Center Inhibition de la thymine dna glycosylase dans le traitement du cancer
CA2941632C (fr) * 2014-03-13 2023-10-24 Vasilios VOUDOURIS Dispersions solides de bendamustine et perfusion continue
JP6457696B2 (ja) 2015-07-23 2019-01-23 アンスティテュ・キュリＩｎｓｔｉｔｕｔ Ｃｕｒｉｅ 癌を処置するためのＤｂａｉｔ分子とＰＡＲＰインヒビターとの組合せの使用
GB201519573D0 (en) 2015-11-05 2015-12-23 King S College London Combination
WO2018162439A1 (fr) 2017-03-08 2018-09-13 Onxeo Nouveau biomarqueur prédictif de la sensibilité à un traitement du cancer avec une molécule dbait
CA3092779A1 (fr) 2018-03-13 2019-09-19 Onxeo Molecule dbait contre la resistance acquise dans le traitement du cancer
WO2021148581A1 (fr) 2020-01-22 2021-07-29 Onxeo Nouvelle molécule dbait et son utilisation

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5204335A (en) * 1986-10-31 1993-04-20 Asta Pharma Aktiengesellschaft Ifosfamide lyophilisate and process for its preparation
US5227373A (en) * 1991-10-23 1993-07-13 Bristol-Myers Squibb Co. Lyophilized ifosfamide compositions
DE69329503T2 (de) * 1992-11-13 2001-05-03 Idec Pharma Corp Therapeutische Verwendung von chimerischen und markierten Antikörpern, die gegen ein Differenzierung-Antigen gerichtet sind, dessen Expression auf menschliche B Lymphozyt beschränkt ist, für die Behandlung von B-Zell-Lymphoma
US5595721A (en) * 1993-09-16 1997-01-21 Coulter Pharmaceutical, Inc. Radioimmunotherapy of lymphoma using anti-CD20
ATE187071T1 (de) * 1993-10-27 1999-12-15 Upjohn Co Stabilisiertes prostaglandin e1
US5955504A (en) * 1995-03-13 1999-09-21 Loma Linda University Medical Center Colorectal chemoprotective composition and method of preventing colorectal cancer
DE19529057B4 (de) * 1995-08-08 2007-12-13 Baxter Healthcare S.A. Ifosfamid-Lyophilisat-Zubereitungen
GB9524334D0 (en) * 1995-11-28 1996-01-31 Philips Electronics Nv Mos transistor
US6034256A (en) * 1997-04-21 2000-03-07 G.D. Searle & Co. Substituted benzopyran derivatives for the treatment of inflammation
US20040072889A1 (en) * 1997-04-21 2004-04-15 Pharmacia Corporation Method of using a COX-2 inhibitor and an alkylating-type antineoplastic agent as a combination therapy in the treatment of neoplasia
US6077850A (en) * 1997-04-21 2000-06-20 G.D. Searle & Co. Substituted benzopyran analogs for the treatment of inflammation
ES2255287T3 (es) * 1998-07-09 2006-06-16 Cephalon, Inc. Composiciones para el tratamiento de la leucemia linfocitica cronica.
US5972912A (en) * 1998-12-17 1999-10-26 S.P. Pharmaceuticals Method for lyophilizing ifosfamide
US6569402B1 (en) * 1998-12-18 2003-05-27 Bristol-Myers Squibb Pharma Company Vitronectin receptor antagonist pharmaceuticals
US6380210B1 (en) * 1999-04-02 2002-04-30 Neurogen Corporation Heteroaryl fused aminoalkyl-imidazole derivatives: selective modulators of GABAa receptors
US6545034B1 (en) * 1999-07-23 2003-04-08 The Regents Of The University Of California Use of etodolac for the treatment of chronic lymphocytic leukemia
US20040152672A1 (en) * 2000-08-09 2004-08-05 Carson Dennis A. Indole compounds useful for the treatment of cancer
PL362979A1 (en) * 2000-12-11 2004-11-02 Takeda Chemical Industries, Ltd. Medicinal compositions improved in solublity in water
CA2431322A1 (fr) * 2000-12-11 2002-06-20 Eiji Nara Compositions medicamenteuses presentant une meilleure absorbabilite
ATE428372T1 (de) * 2001-10-15 2009-05-15 Hemoteq Ag Beschichtung von stents zur verhinderung von restenose
US6613927B1 (en) * 2002-02-08 2003-09-02 American Pharmaceutical Partners, Inc. Sterile lyophilized ifosfamide and associated methods
ES2321082T3 (es) * 2002-05-09 2009-06-02 Hemoteq Ag Productos medicos que comprenden un revestimiento hemocompatible, produccion y uso de los mismos.
US20040096436A1 (en) * 2002-08-02 2004-05-20 Regents Of The University Of California Methods for inhibiting protein kinases in cancer cells
US6966329B2 (en) * 2003-01-27 2005-11-22 Hydraforce, Inc. Proportional pilot-operated flow control valve
DE10304403A1 (de) * 2003-01-28 2004-08-05 Röhm GmbH & Co. KG Verfahren zur Herstellung einer oralen Arzneiform mit unmittelbarem Zerfall und Wirkstofffreisetzung
CA2516191A1 (fr) * 2003-02-14 2004-09-02 Salmedix, Inc Compositions et methodes de detection et de traitement des cancers a deficience de methylthioadenosine phosphorylase

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