JP2008509224A5 - - Google Patents
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- Publication number
- JP2008509224A5 JP2008509224A5 JP2007525717A JP2007525717A JP2008509224A5 JP 2008509224 A5 JP2008509224 A5 JP 2008509224A5 JP 2007525717 A JP2007525717 A JP 2007525717A JP 2007525717 A JP2007525717 A JP 2007525717A JP 2008509224 A5 JP2008509224 A5 JP 2008509224A5
- Authority
- JP
- Japan
- Prior art keywords
- medicament
- hydroxytyrosol
- homocysteine
- subject
- rich
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- JUUBCHWRXWPFFH-UHFFFAOYSA-N Hydroxytyrosol Chemical compound OCCC1=CC=C(O)C(O)=C1 JUUBCHWRXWPFFH-UHFFFAOYSA-N 0.000 claims 50
- 239000003814 drug Substances 0.000 claims 35
- 235000003248 hydroxytyrosol Nutrition 0.000 claims 25
- 229940095066 hydroxytyrosol Drugs 0.000 claims 25
- FFFHZYDWPBMWHY-VKHMYHEASA-N L-homocysteine Chemical compound OC(=O)[C@@H](N)CCS FFFHZYDWPBMWHY-VKHMYHEASA-N 0.000 claims 21
- 108010074051 C-Reactive Protein Proteins 0.000 claims 7
- 102100032752 C-reactive protein Human genes 0.000 claims 7
- 238000002203 pretreatment Methods 0.000 claims 6
- 230000004968 inflammatory condition Effects 0.000 claims 5
- RFWGABANNQMHMZ-UHFFFAOYSA-N 8-acetoxy-7-acetyl-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]quinoline Natural products CC=C1C(CC(=O)OCCC=2C=C(O)C(O)=CC=2)C(C(=O)OC)=COC1OC1OC(CO)C(O)C(O)C1O RFWGABANNQMHMZ-UHFFFAOYSA-N 0.000 claims 4
- HKVGJQVJNQRJPO-UHFFFAOYSA-N Demethyloleuropein Natural products O1C=C(C(O)=O)C(CC(=O)OCCC=2C=C(O)C(O)=CC=2)C(=CC)C1OC1OC(CO)C(O)C(O)C1O HKVGJQVJNQRJPO-UHFFFAOYSA-N 0.000 claims 4
- RFWGABANNQMHMZ-HYYSZPHDSA-N Oleuropein Chemical compound O([C@@H]1OC=C([C@H](C1=CC)CC(=O)OCCC=1C=C(O)C(O)=CC=1)C(=O)OC)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O RFWGABANNQMHMZ-HYYSZPHDSA-N 0.000 claims 4
- 238000012544 monitoring process Methods 0.000 claims 4
- 235000011576 oleuropein Nutrition 0.000 claims 4
- RFWGABANNQMHMZ-CARRXEGNSA-N oleuropein Natural products COC(=O)C1=CO[C@@H](O[C@H]2O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]2O)C(=CC)[C@H]1CC(=O)OCCc3ccc(O)c(O)c3 RFWGABANNQMHMZ-CARRXEGNSA-N 0.000 claims 4
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 3
- 208000024172 Cardiovascular disease Diseases 0.000 claims 2
- 150000008442 polyphenolic compounds Chemical class 0.000 claims 2
- 235000013824 polyphenols Nutrition 0.000 claims 2
- 210000003296 saliva Anatomy 0.000 claims 2
- 208000027866 inflammatory disease Diseases 0.000 claims 1
- 230000036470 plasma concentration Effects 0.000 claims 1
- 208000019553 vascular disease Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60023804P | 2004-08-09 | 2004-08-09 | |
| US67246005P | 2005-04-18 | 2005-04-18 | |
| PCT/US2005/028179 WO2006020588A1 (en) | 2004-08-09 | 2005-08-09 | Olive compositions and methods for treating inflammatory conditions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008509224A JP2008509224A (ja) | 2008-03-27 |
| JP2008509224A5 true JP2008509224A5 (cg-RX-API-DMAC7.html) | 2008-10-02 |
Family
ID=35907742
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007525717A Pending JP2008509224A (ja) | 2004-08-09 | 2005-08-09 | 炎症状態を治療するためのオリーブ組成物及び方法 |
Country Status (3)
| Country | Link |
|---|---|
| US (2) | US20080300198A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2008509224A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2006020588A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090076142A1 (en) * | 2005-05-09 | 2009-03-19 | The Trustees Of The University Of Pennsylvania | Use of the irritating principal oleocanthal in olive oil, as well as structurally and functionally similar compounds |
| US9789149B2 (en) | 2005-07-19 | 2017-10-17 | Creagri, Inc. | Vegetation water composition for treatment of inflammatory skin conditions |
| JP5339373B2 (ja) * | 2006-07-14 | 2013-11-13 | ディーエスエム アイピー アセッツ ビー．ブイ． | 組成物および炎症障害の治療、共治療または予防のためのその使用 |
| JP5175481B2 (ja) * | 2006-10-23 | 2013-04-03 | エーザイフード・ケミカル株式会社 | 軟骨再生促進剤 |
| JP2008120716A (ja) * | 2006-11-10 | 2008-05-29 | Eisai Food Chemical Kk | 抗炎症剤 |
| WO2008128552A1 (en) * | 2007-04-18 | 2008-10-30 | Dsm Ip Assets B.V. | Novel use of hydroxytyrosol and olive extracts/concentrates containing it |
| EP1982706A1 (en) * | 2007-04-18 | 2008-10-22 | DSMIP Assets B.V. | Use of hydroxytyrosol for the treatment of cartilage injury |
| CN101945651A (zh) * | 2007-12-12 | 2011-01-12 | 帝斯曼知识产权资产管理有限公司 | 包含羟基酪醇和软骨素的组合物及其用于治疗、辅助治疗或预防炎性病症的用途 |
| US8796315B2 (en) | 2009-06-25 | 2014-08-05 | Darlene E. McCord | Methods for improved wound closure employing olivamine and human umbilical vein endothelial cells |
| WO2010151778A2 (en) | 2009-06-25 | 2010-12-29 | Darlene Mccord | Topical compositions and methods for wound care |
| CA2769819C (en) | 2009-08-10 | 2015-07-21 | Darlene Mccord | Nutritional supplements |
| EP2925307B1 (en) | 2012-11-30 | 2020-10-28 | McCord, Darlene E. | Hydroxytyrosol and oleuropein compositions for induction of dna damage, cell death and lsd1 inhibition |
| WO2014100715A2 (en) * | 2012-12-21 | 2014-06-26 | Ehrenkranz Joel R L | Supplements and monitoring systems for dosing of the supplements |
| ITMI20131815A1 (it) * | 2013-10-31 | 2015-05-01 | Fattoria La Vialla Di Gianni Anton Io E Bandino L | Uso antinfiammatorio di fitocomplessi liquidi da olive |
| CA2962487A1 (en) * | 2014-09-24 | 2016-03-31 | Phytogen Medical Foods S.L | Pharmaceutical product, medical food or dietary supplement for preventing cancer and inflammatory diseases |
| GR1008734B (el) | 2014-11-26 | 2016-04-05 | ΚΡΕΤΑ ΦΑΡΜ ΑΝΩΝΥΜΟΣ ΒΙΟΜΗΧΑΝΙΚΗ ΚΑΙ ΕΜΠΟΡΙΚΗ ΕΤΑΙΡΕΙΑ με δ.τ. "ΚΡΕΤΑ ΦΑΡΜ Α.Β.Ε.Ε." | Υδατικο εκχυλισμα ελιας με μεταβολικες και καρδιο-προστατευτικες ιδιοτητες. |
| JP5956669B1 (ja) * | 2015-12-18 | 2016-07-27 | サンスター株式会社 | 低カロリーチョコレート組成物 |
| US10342802B2 (en) | 2016-10-04 | 2019-07-09 | Nutramax Laboratories, Inc. | Compositions comprising hydroxytyrosol and boswellic acid |
| CN109789110A (zh) * | 2016-10-04 | 2019-05-21 | 纽崔玛氏科技有限责任公司 | 包含羟基酪醇和乳香酸的组合物 |
| US11007171B2 (en) * | 2017-07-13 | 2021-05-18 | Summit Innovation Labs, LLC | Treatment and prevention of joint disorders |
| EP3706759B1 (en) * | 2017-11-08 | 2023-11-15 | Société des Produits Nestlé S.A. | Homovanillyl alcohol (hva), hva isomer, methods of making compositions comprising such compounds, and methods using such compounds |
| JP2020193852A (ja) * | 2019-05-28 | 2020-12-03 | 株式会社ファンケル | 非侵襲的な血清亜鉛値の推定方法 |
| EP4216735A1 (en) * | 2020-09-24 | 2023-08-02 | Mars Incorporated | Food compositions and applications thereof |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4522119A (en) * | 1980-12-23 | 1985-06-11 | Fps Development Partnership | Olive oil recovery |
| US4452744A (en) * | 1980-12-23 | 1984-06-05 | Fps Development Partnership | Olive oil recovery |
| US4370274A (en) * | 1980-12-23 | 1983-01-25 | Fps Development Partnership | Olive oil recovery |
| ATE123287T1 (de) * | 1991-03-21 | 1995-06-15 | Dior Christian Parfums | Kaffeinsaure-derivate,oraposid,ihre kosmetische oder pharmazeutische zusammensetzungen,insbesondere mit dermatologischer wirkung. |
| WO1996014064A1 (en) * | 1994-11-07 | 1996-05-17 | Strecker, Robert, B. | Method and composition for antiviral therapy |
| US5998641A (en) * | 1997-01-31 | 1999-12-07 | Unilever Patent Holdings | Debittering of olive oil |
| US5714150A (en) * | 1997-01-08 | 1998-02-03 | Nachman; Leslie | Method for producing extract of olive leaves |
| US6984667B2 (en) * | 1998-04-08 | 2006-01-10 | Theta Biomedical Consulting And Development Co. | Synergistic proteoglycan compositions for inflammatory conditions |
| DE69902645T2 (de) * | 1998-04-14 | 2003-04-30 | Unilever N.V., Rotterdam | Verstärkung von pflanzlichem fett mit antioxidantien |
| US6936287B1 (en) * | 1998-07-23 | 2005-08-30 | Creagri, Inc. | Water-soluble extract from olives |
| US6197308B1 (en) * | 1998-07-23 | 2001-03-06 | Creagri L.L.C. | Water-soluble extract from olives |
| US6165475A (en) * | 1998-07-23 | 2000-12-26 | Creagri, Inc. | Water-soluble extract from olives |
| EP1139797A2 (en) * | 1998-12-22 | 2001-10-10 | Unilever N.V. | Food compositions fortified with anti-oxidants |
| KR20020063877A (ko) * | 1999-10-14 | 2002-08-05 | 니신 오일 밀스 가부시키가이샤 | 피부개선제, 피부노화 방지제, 미백제 및 피부외용제 |
| US6358542B2 (en) * | 1999-12-20 | 2002-03-19 | Usana, Inc. | Antioxidant compositions extracted from olives and olive by-products |
| AU2000258901A1 (en) * | 2000-04-06 | 2001-10-23 | Nicholas V. Perricone | Treatment of skin damage using olive oil polyphenols |
| US6440465B1 (en) * | 2000-05-01 | 2002-08-27 | Bioderm, Inc. | Topical composition for the treatment of psoriasis and related skin disorders |
| US7713569B2 (en) * | 2000-09-01 | 2010-05-11 | Creagri, Inc. | Hydroxytyrosol-rich composition from olive vegetation water and method of use thereof |
| WO2002018310A1 (en) * | 2000-09-01 | 2002-03-07 | Creagri, Inc. | Method of obtaining a hydroxytyrosol-rich composition from vegetation water |
| PT1369407E (pt) * | 2001-02-15 | 2009-01-22 | Consejo Superior Investigacion | Processo de obtenção de hidroxitirosol purificado a partir de produtos e subprodutos derivados da oliveira |
| US6734449B2 (en) * | 2001-11-20 | 2004-05-11 | Nexpress Solutions Llc | Device for detecting the location of an edge of a transparent material, web edge control and printing press |
| WO2003066034A2 (en) * | 2002-02-08 | 2003-08-14 | Lavipharm S.A. | Use of compounds and compositions derived form olives for protecting cells against dna damage |
| WO2003068171A2 (en) * | 2002-02-13 | 2003-08-21 | Creagri, Inc. | Method and composition for treatment of inflammation and aids-associated neurological disorders |
| US6743449B2 (en) * | 2002-02-13 | 2004-06-01 | Skinceuticals, Inc. | Topical composition comprising olive leaf extract |
| ES2193874B1 (es) * | 2002-04-03 | 2005-03-01 | Puleva Biotech, S.A. | Compuestos naturales y derivados de estos para la prevencion y el tratamiento de enfermedades cardiovasculares, hepaticas, renales y cosmeticas. |
| US20050113287A1 (en) * | 2003-10-21 | 2005-05-26 | Motion Potion, Inc. | Composition to enhance joint function and repair |
-
2005
- 2005-08-09 US US11/659,861 patent/US20080300198A1/en not_active Abandoned
- 2005-08-09 JP JP2007525717A patent/JP2008509224A/ja active Pending
- 2005-08-09 WO PCT/US2005/028179 patent/WO2006020588A1/en not_active Ceased
-
2011
- 2011-06-08 US US13/156,275 patent/US20110257117A1/en not_active Abandoned
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