JP2008505695A - 出産過程の測定方法 - Google Patents

出産過程の測定方法 Download PDF

Info

Publication number
JP2008505695A
JP2008505695A JP2007520342A JP2007520342A JP2008505695A JP 2008505695 A JP2008505695 A JP 2008505695A JP 2007520342 A JP2007520342 A JP 2007520342A JP 2007520342 A JP2007520342 A JP 2007520342A JP 2008505695 A JP2008505695 A JP 2008505695A
Authority
JP
Japan
Prior art keywords
lactate
data
concentration
lactate concentration
fetal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2007520342A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008505695A5 (enExample
Inventor
ヨハン イツェル
エヴァ イツェル
Original Assignee
オブステケア インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by オブステケア インコーポレイテッド filed Critical オブステケア インコーポレイテッド
Publication of JP2008505695A publication Critical patent/JP2008505695A/ja
Publication of JP2008505695A5 publication Critical patent/JP2008505695A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/43—Detecting, measuring or recording for evaluating the reproductive systems
    • A61B5/4306—Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
    • A61B5/4343—Pregnancy and labour monitoring, e.g. for labour onset detection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/43—Detecting, measuring or recording for evaluating the reproductive systems
    • A61B5/4306—Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
    • A61B5/4343—Pregnancy and labour monitoring, e.g. for labour onset detection
    • A61B5/435—Assessing cervix alteration or dilation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/43—Detecting, measuring or recording for evaluating the reproductive systems
    • A61B5/4306—Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
    • A61B5/4343—Pregnancy and labour monitoring, e.g. for labour onset detection
    • A61B5/4362—Assessing foetal parameters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7271—Specific aspects of physiological measurement analysis
    • A61B5/7275—Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/40—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/63—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/70—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A61B10/0048—Devices for taking samples of body liquids for taking amniotic fluid samples
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2503/00—Evaluating a particular growth phase or type of persons or animals
    • A61B2503/02—Foetus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/103—Measuring devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/107—Measuring physical dimensions, e.g. size of the entire body or parts thereof
    • A61B5/1076—Measuring physical dimensions, e.g. size of the entire body or parts thereof for measuring dimensions inside body cavities, e.g. using catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14539—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring pH
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/20—Oxygen containing
    • Y10T436/200833—Carbonyl, ether, aldehyde or ketone containing
    • Y10T436/201666—Carboxylic acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medical Informatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Primary Health Care (AREA)
  • Pregnancy & Childbirth (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Optics & Photonics (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Business, Economics & Management (AREA)
  • Artificial Intelligence (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Physiology (AREA)
  • General Business, Economics & Management (AREA)
  • Signal Processing (AREA)
  • Chemical & Material Sciences (AREA)
  • Pediatric Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Data Mining & Analysis (AREA)
  • Databases & Information Systems (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Surgical Instruments (AREA)
JP2007520342A 2004-07-07 2005-06-28 出産過程の測定方法 Pending JP2008505695A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52181404P 2004-07-07 2004-07-07
PCT/US2005/022670 WO2006017004A1 (en) 2004-07-07 2005-06-28 Method for monitoring a childbirth process

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012009097A Division JP5549893B2 (ja) 2004-07-07 2012-01-19 出産過程の測定方法

Publications (2)

Publication Number Publication Date
JP2008505695A true JP2008505695A (ja) 2008-02-28
JP2008505695A5 JP2008505695A5 (enExample) 2008-08-14

Family

ID=35839563

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2007520342A Pending JP2008505695A (ja) 2004-07-07 2005-06-28 出産過程の測定方法
JP2012009097A Expired - Fee Related JP5549893B2 (ja) 2004-07-07 2012-01-19 出産過程の測定方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2012009097A Expired - Fee Related JP5549893B2 (ja) 2004-07-07 2012-01-19 出産過程の測定方法

Country Status (5)

Country Link
US (2) US8172767B2 (enExample)
EP (1) EP1763315A4 (enExample)
JP (2) JP2008505695A (enExample)
CN (1) CN101010032A (enExample)
WO (1) WO2006017004A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6464986B1 (en) 2000-04-14 2002-10-15 Allegan Sales, Inc. Method for treating pain by peripheral administration of a neurotoxin
JP6498404B2 (ja) * 2014-09-11 2019-04-10 キヤノンメディカルシステムズ株式会社 パルトグラム表示装置
CN108697840B (zh) * 2015-10-07 2022-05-13 迈奎特心肺有限公司 用户界面
BR112021009203A2 (pt) * 2018-11-14 2021-08-03 Mark Evans método e aparelho para reduzir o risco de lesão neurológica a uma criança humana no período neonatal
CN115105682B (zh) * 2022-06-26 2023-08-01 广州爱听贝科技有限公司 一种连续乳酸监测指导缩宫素使用的方法及系统

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05123324A (ja) * 1991-11-05 1993-05-21 Hakujiyuuji Kk 羊水の破水鑑別パツド
JPH078498A (ja) * 1993-06-25 1995-01-13 Koji Yoshida ちつ内の生理状態および生理現象などとその変化を感知 し計測する方法とちつ内の生理状態および生理現象など とその変化の感知機能と計測機能を有する計測装置とそ の計測装置の医療上の診断のための使用方法と医療上の 診断方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8722899D0 (en) * 1987-09-30 1987-11-04 Kirk D L Fetal monitoring during labour
FI86777C (fi) * 1990-12-31 1992-10-12 Medix Biochemica Ab Oy Foerfarande foer diagnosticering av bristningen av fosterhinnorna samt reagensfoerpackning foer anvaendning daervid
US5377673A (en) * 1993-03-22 1995-01-03 Van Dell; Peter Intrauterine monitoring device
US5791344A (en) * 1993-11-19 1998-08-11 Alfred E. Mann Foundation For Scientific Research Patient monitoring system
US5935061A (en) * 1997-01-03 1999-08-10 Biosense, Inc. Obstetrical instrument system and method
US6560471B1 (en) 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
NL1018249C2 (nl) * 2001-06-08 2002-12-10 Tno Inrichting voor het bepalen van foetale reserves tijdens een bevalling.
US7096053B2 (en) * 2001-10-02 2006-08-22 Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California Internal biochemical sensing device
US20050101841A9 (en) * 2001-12-04 2005-05-12 Kimberly-Clark Worldwide, Inc. Healthcare networks with biosensors
US20040100376A1 (en) 2002-11-26 2004-05-27 Kimberly-Clark Worldwide, Inc. Healthcare monitoring system
EP1663009A4 (en) * 2003-09-15 2009-08-05 Obstecare Inc Method for monitoring a childbirth process

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05123324A (ja) * 1991-11-05 1993-05-21 Hakujiyuuji Kk 羊水の破水鑑別パツド
JPH078498A (ja) * 1993-06-25 1995-01-13 Koji Yoshida ちつ内の生理状態および生理現象などとその変化を感知 し計測する方法とちつ内の生理状態および生理現象など とその変化の感知機能と計測機能を有する計測装置とそ の計測装置の医療上の診断のための使用方法と医療上の 診断方法

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JPN6010043560, ＫＯＳＫＩ，Ｋ．Ｇ． ｅｔ ａｌ．, "Ａｍｎｉｏｔｉｃ Ｆｌｕｉｄ Ｃｏｍｐｏｓｉｔｉｏｎ Ｒｅｓｐｏｎｄｓ ｔｏ Ｃｈａｎｇｅｓ ｉｎ Ｍａｔｅｒｎａｌ Ｄｉｅｔａｒｙ Ｃａｒｂｏｈｙｄｒａｔｅ ａｎｄ ｉｓ Ｒｅｌａｔｅｄ ｔｏ Ｍｅ", Ｊ．Ｎｕｔｒ．, 1992, Ｖｏｌ．１２２， Ｎｏ．２, ｐ．３８５−３９２ *
JPN6010043561, 椛島勝一 他, "ＧＣ／ＭＳによる羊水，新生児初回尿，さい帯血，母体血中の有機酸組成に関する研究", 産婦人科の世界, 1981, Ｖｏｌ．３３ Ｎｏ．８, ｐ．９２３−９２７ *
JPN6010043563, ＭＩＴＳＵＴＡＫＥ，Ｋ． ｅｔ ａｌ．, "Ｐｒｏｆｉｌｉｎｇ ｏｆ ｏｒｇａｎｉｃ ａｃｉｄｓ ｉｎ ｈｕｍａｎ ａｍｎｉｏｔｉｃ ｆｌｕｉｄ ａｎｄ ｔｈｅ ｄｙｓｍａｔｕｒｅ ｆｅｔｕｓ．", Ａｎｎｕ Ｃｏｎｆ Ｍａｓｓ Ｓｐｅｃｔｒｏｍ Ａｌｌｉｅｄ Ｔｏｐ, 1981, Ｖｏｌ．２９ｔｈ, ｐ．２７３−２７４ *

Also Published As

Publication number Publication date
US8172767B2 (en) 2012-05-08
EP1763315A4 (en) 2009-03-04
JP5549893B2 (ja) 2014-07-16
WO2006017004A1 (en) 2006-02-16
JP2012110734A (ja) 2012-06-14
CN101010032A (zh) 2007-08-01
US8951212B2 (en) 2015-02-10
US20120232428A1 (en) 2012-09-13
EP1763315A1 (en) 2007-03-21
US20070166830A1 (en) 2007-07-19

Similar Documents

Publication Publication Date Title
Banos et al. Definition of failed induction of labor and its predictive factors: two unsolved issues of an everyday clinical situation
JP5549893B2 (ja) 出産過程の測定方法
Vasak et al. Uterine electromyography for identification of first-stage labor arrest in term nulliparous women with spontaneous onset of labor
Piquard et al. Are there two biological parts in the second stage of labor?
US20250253055A1 (en) Methods and apparatus for reducing the risk, and identifying the existence, of neurological injury to a human fetus during and before labor
Sultana et al. Safety of caesarean myomectomy
EP2486854B1 (en) Method for monitoring a childbirth process
Talaulikar et al. Labour admission test
EP1933707B1 (en) Method for monitoring a childbirth process
Alam et al. The Fetomaternal Outcome of Induction of Labour in Idiopathic Oligohydramnios
Ettner Hospital technology breeds pathology
KR102482468B1 (ko) 조산에 대한 정보 제공 방법 및 이를 적용한 디바이스
CN114864091A (zh) 用于足月待引产孕妇宫颈成熟度评价的方法、设备及介质
RU2223029C2 (ru) Способ определения времени наступления родов при дородовом излитии околоплодных вод
CN117877719A (zh) 二胎阴道分娩孕产妇产后出血预测列线图模型、构建方法、产后出血发生概率预测方法、孕产妇分类方法及应用
Welsh et al. Intensive blood pressure control in chronically hypertensive mice
Gandhi et al. Electronic fetal heart rate monitoring
JP2016531305A (ja) 胎児仮死の診断
Saxton et al. Cite as
Barton et al. 123 Interleukin 1 receptor antagonist gene polymorphism and adverse pregnancy outcome in 207 pregnancies
Cohen et al. The role of ultrasound in the clinical practice of obstetrics
Yadav et al. To Assess the Maternal and Perinatal Outcome with Isolated Oligohydramnios in Third Trimester of Pregnancy
Arulkumaran et al. Labor Admission Test
Test Labor Admission Test
Rhee et al. The Relationship Between Plasma Inflammatory Cytokines and Labor Pain

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20080627

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20080627

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20100802

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20101102

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20101110

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20110202

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20110719

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20111012

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20111019

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20120604