JP2008501722A5 - - Google Patents
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- Publication number
- JP2008501722A5 JP2008501722A5 JP2007519572A JP2007519572A JP2008501722A5 JP 2008501722 A5 JP2008501722 A5 JP 2008501722A5 JP 2007519572 A JP2007519572 A JP 2007519572A JP 2007519572 A JP2007519572 A JP 2007519572A JP 2008501722 A5 JP2008501722 A5 JP 2008501722A5
- Authority
- JP
- Japan
- Prior art keywords
- disease
- disorder
- pharmaceutical composition
- composition according
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 13
- 201000010099 disease Diseases 0.000 claims 7
- 208000035475 disorder Diseases 0.000 claims 6
- 239000008194 pharmaceutical composition Substances 0.000 claims 5
- 150000001875 compounds Chemical class 0.000 claims 2
- 208000027866 inflammatory disease Diseases 0.000 claims 2
- 208000014674 injury Diseases 0.000 claims 2
- 206010003210 Arteriosclerosis Diseases 0.000 claims 1
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 claims 1
- 206010018364 Glomerulonephritis Diseases 0.000 claims 1
- 208000022559 Inflammatory bowel disease Diseases 0.000 claims 1
- 201000004681 Psoriasis Diseases 0.000 claims 1
- 206010063837 Reperfusion injury Diseases 0.000 claims 1
- 206010038687 Respiratory distress Diseases 0.000 claims 1
- 206010040047 Sepsis Diseases 0.000 claims 1
- 208000027418 Wounds and injury Diseases 0.000 claims 1
- 230000004913 activation Effects 0.000 claims 1
- 208000026935 allergic disease Diseases 0.000 claims 1
- 208000011775 arteriosclerosis disease Diseases 0.000 claims 1
- 208000006673 asthma Diseases 0.000 claims 1
- 206010008118 cerebral infarction Diseases 0.000 claims 1
- 208000026106 cerebrovascular disease Diseases 0.000 claims 1
- 230000006378 damage Effects 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 230000004957 immunoregulator effect Effects 0.000 claims 1
- 230000009545 invasion Effects 0.000 claims 1
- 230000000302 ischemic effect Effects 0.000 claims 1
- 210000000265 leukocyte Anatomy 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000001404 mediated effect Effects 0.000 claims 1
- 208000010125 myocardial infarction Diseases 0.000 claims 1
- 208000031225 myocardial ischemia Diseases 0.000 claims 1
- 210000000056 organ Anatomy 0.000 claims 1
- 230000010410 reperfusion Effects 0.000 claims 1
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 201000000596 systemic lupus erythematosus Diseases 0.000 claims 1
- 230000008733 trauma Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57850004P | 2004-06-10 | 2004-06-10 | |
| PCT/CA2005/000891 WO2005121095A1 (en) | 2004-06-10 | 2005-06-07 | Pyridine analogs as c5a antagonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008501722A JP2008501722A (ja) | 2008-01-24 |
| JP2008501722A5 true JP2008501722A5 (cg-RX-API-DMAC7.html) | 2008-05-08 |
Family
ID=35502992
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007519572A Pending JP2008501722A (ja) | 2004-06-10 | 2005-06-07 | Ｃ５ａ拮抗剤としてのピリジン誘導体 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US7429666B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1758865A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2008501722A (cg-RX-API-DMAC7.html) |
| CN (1) | CN1968931A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2005251839A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2568673A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2005121095A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7429666B2 (en) * | 2004-06-10 | 2008-09-30 | Merck Frosst Canada Ltd. | Pyridine analogs as C5a antagonists |
| US8927546B2 (en) * | 2006-02-28 | 2015-01-06 | Dart Neuroscience (Cayman) Ltd. | Therapeutic piperazines |
| NZ570844A (en) * | 2006-02-28 | 2011-11-25 | Helicon Therapeutics Inc | Therapeutic piperazines as PDE4 inhibitors |
| CN101553244B (zh) * | 2006-07-21 | 2013-01-02 | 普罗米克斯有限公司 | 内膜增生和相关病状的治疗 |
| KR20090074219A (ko) * | 2006-10-04 | 2009-07-06 | 쉐링 코포레이션 | 트롬빈 수용체 길항제로서의 비사이클릭 및 트리사이클릭 유도체 |
| CN103168031A (zh) * | 2010-10-20 | 2013-06-19 | 霍夫曼-拉罗奇有限公司 | 作为ampk活化剂的四氢喹啉衍生物 |
| US8846656B2 (en) | 2011-07-22 | 2014-09-30 | Novartis Ag | Tetrahydropyrido-pyridine and tetrahydropyrido-pyrimidine compounds and use thereof as C5a receptor modulators |
| US9289467B2 (en) | 2011-08-10 | 2016-03-22 | Case Western Reserve University | Compositions and methods for treating bone conditions |
| CN108508130B (zh) * | 2018-04-11 | 2020-01-17 | 国家烟草质量监督检验中心 | 一种超高效合相色谱-串联质谱技术拆分、测定手性农药甲霜灵和烯酰吗啉对映体的方法 |
| US20240293380A1 (en) * | 2021-06-16 | 2024-09-05 | The Cleveland Clinic Foundation | Protease inhibitors and methods of use |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102050758A (zh) | 2000-09-14 | 2011-05-11 | 田边三菱制药株式会社 | 酰胺衍生物及其制备药物的用途 |
| CA2479930A1 (en) * | 2002-03-28 | 2003-10-09 | Neurogen Corporation | Substituted tetrahydroisoquinolines as c5a receptor modulators |
| EP1487796A4 (en) | 2002-03-28 | 2005-11-16 | Neurogen Corp | SUBSTITUTED BIARYLAMIDES AS MODULATORS OF THE C5A RECEPTOR |
| US20040014782A1 (en) * | 2002-03-29 | 2004-01-22 | Krause James E. | Combination therapy for the treatment of diseases involving inflammatory components |
| US7429666B2 (en) * | 2004-06-10 | 2008-09-30 | Merck Frosst Canada Ltd. | Pyridine analogs as C5a antagonists |
-
2005
- 2005-02-08 US US11/053,623 patent/US7429666B2/en not_active Expired - Fee Related
- 2005-06-07 CA CA002568673A patent/CA2568673A1/en not_active Abandoned
- 2005-06-07 CN CNA2005800192053A patent/CN1968931A/zh active Pending
- 2005-06-07 WO PCT/CA2005/000891 patent/WO2005121095A1/en not_active Ceased
- 2005-06-07 AU AU2005251839A patent/AU2005251839A1/en not_active Abandoned
- 2005-06-07 EP EP05754860A patent/EP1758865A4/en not_active Withdrawn
- 2005-06-07 JP JP2007519572A patent/JP2008501722A/ja active Pending
-
2008
- 2008-09-18 US US12/284,122 patent/US20090023774A1/en not_active Abandoned