JP2008307241A - Blocking prevention device - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a blocking prevention device for preventing a palm from blocking an opening part at the proximal end of an injection cylinder in a communicating operation by mounting the device onto the flange part of the injection cylinder. <P>SOLUTION: The blocking prevention device to be attached onto the flange of the injection cylinder includes: a hand pressure board; a rod insertion part arranged in the hand pressure board; an injection cylinder fitting part arranged on the lower surface of the hand pressure board so as to obtain a space between the hand pressure board and the flange; and a breather part arranged in a part other than the hand pressure part and communicated with the space. <P>COPYRIGHT: (C)2009,JPO&INPIT

Description

  The present invention relates to an obstruction prevention tool attached to a flange of a syringe barrel.

  Conventionally, there is a prefilled syringe that stores a chemical solution that can be directly used in the syringe and that can directly use the chemical solution. However, the chemical solution that can be stored inside the syringe is limited to a chemical solution that is stable even if stored in the state of the chemical solution.

  Some drugs have extremely low efficacy when prepared and stored, and others that react with each drug that is prepared. It cannot be stored. Therefore, the state before adjustment, that is, the solution (medical solution) and the drug are stored in separate containers (particularly vials), and each drug is prepared immediately before use.

  As a method for adjusting the solution and medicine stored in each vial, for example, there is a method in which each vial is attached to each needle tip of a transfer tool provided with a hollow double-ended needle (see “ No. 2007-61219 "). Since the inside of the drug vial is kept in a reduced pressure state so that the inflow of the solution is facilitated, it can be prepared by communicating the solution vial and the drug vial with a double-ended needle in this order.

  As a developed version of the above-mentioned transfer tool for mounting the vials together, there is a transfer tool capable of mounting a prefilled syringe containing a solution and a decompression vial filled with a medicine. The feature of this is that when the prefilled syringe and the vial are communicated with each other, since the pressure in the vial is lower than the atmospheric pressure, air flows from the base end of the barrel to the base end of the gasket. The solution is pushed toward the tip, and the lysate is quickly poured into the vial to be prepared.

  At this time, if the plunger rod is not attached to the prefilled syringe, the flange portion can be pushed downward with a palm. For this reason, during preparation, a pre-filled syringe without a rod is preferably employed because a stable communication operation is possible when the pre-filled syringe is in a state without a rod. However, in operation, when the flange portion is pressed with a palm, the proximal end opening of the syringe barrel is blocked by the palm, and the space between the gasket and the palm in the syringe barrel may be blocked. As a result, since air does not flow into the barrel from the proximal end opening, the movement of the gasket in the prefilled syringe is hindered, and there is a possibility that the dissolved solution cannot be quickly injected into the vial.

  In particular, when the drug enclosed in the vial is a protein preparation, the protein preparation is characterized by poor solubility and easy foaming and once formed foam is difficult to disappear. Therefore, due to the palm closing the proximal opening of the syringe barrel, when the solution is not quickly injected into the vial when the solution is introduced into the vial, intermittent inflow of the solution may occur. , Making it easy to foam. Therefore, an instrument is required to prevent the proximal end opening of the syringe barrel from being blocked in the communication operation.

  An object of the present invention is to provide an anti-blocking device which is attached to a flange portion of a syringe barrel to prevent the proximal end opening of the syringe barrel from being blocked with a palm during a communication operation.

Therefore, the present inventors
(1) A clogging prevention device attached to a flange of a syringe barrel, and a space between the pusher plate and the flange on the lower surface side of the pusher plate, a rod insertion portion provided on the pusher plate, and the pusher plate. An occlusion prevention device including a syringe barrel fitting portion provided so as to include a ventilation portion provided in a portion other than the pusher plate and communicating with the space.
(2) The rod insertion portion is formed in a substantially circular hole. Further, the rod insertion portion protrudes in the center direction of the rod insertion portion, and a force is applied from the rod insertion direction and the screwing direction of the rod and the gasket. The occlusion prevention device according to (1), which is provided with a drop-off prevention claw that only shrinks elastically.
Since there is a space between the syringe barrel fitting portion and the pusher plate and a ventilation portion communicating with the space is provided in a portion other than the pusher plate, the pusher plate is held with a palm in the communication operation. It has been found that even if pressed, air can flow from the outside to the proximal end opening of the syringe barrel, leading to the present invention.

  The obstruction-preventing device of the present invention can be easily attached to a flange, can flow air into a syringe proximal end opening, and can quickly prepare a chemical solution, so that it can be suitably used for medical treatment.

  Hereinafter, the obstruction prevention device of the present invention will be described with reference to the drawings. However, the present invention is not limited to the exemplary embodiments described in these drawings.

  FIG. 1A to FIG. 1C are perspective views as viewed from the front side of the upper surface of the presser plate, the front side of the flange receiving side, and the rear side of one embodiment of the blocking prevention device of the present invention. 2A is a top view of the occlusion prevention device shown in FIG. 1, and FIG. 2B is a cross-sectional view taken along the line AA in FIG. 2A, that is, a cross-sectional view of the drop-off preventing claw. FIG. 3A is a front view of the obstruction prevention device shown in FIG. 1, and FIG. 3B is a view showing a state in which the obstruction prevention device of FIG. FIG. 4 is a diagram illustrating a usage state of the obstruction prevention device illustrated in FIG. 1.

  An embodiment of the present invention will be described with reference to FIGS. In the obstruction prevention device of the present invention, a presser plate 1 in which a rod insertion portion 11 that is a substantially circular hole is formed in the center, and a flange receiver 2 are formed so that the presser plate 1 forms one surface of a rectangular frame. ing. The bottom surface of the flange receiver 2 (the surface facing the presser plate 1) has a U shape with a front portion missing, and a U-shaped barrel stopper 21 is formed along the missing portion. Two rail-like ribs 12 projecting downward are formed on the lower surface of the presser plate 1 so as to be parallel to the side wall 3 of the flange receiver 2 and in contact with the rod insertion portion 11. Auxiliary ribs 13 are provided between the ribs 12. A drop-off preventing claw 14 is formed toward the center of the rod insertion part 11 at the contact point between the rail-like rib 12 and the rod insertion part 11 of the rail-like rib 12. With the three ribs, when the prefilled syringe is set in the obstruction prevention device of the present invention, a space 4 is provided between the presser plate 1 and the flange. A syringe barrel fitting portion is formed by the three ribs, the flange receiver 2 and the barrel stopper 21. Moreover, the obstruction | occlusion prevention tool shown in FIG. 1 is a rectangular frame body, and the front and back which are the opening parts become the ventilation | gas_flowing part 5. FIG.

  By making the obstruction prevention tool into the shape of a rectangular frame, the syringe can be slid and inserted from the opening on the front side of the frame, and the rib is provided so as not to contact the pusher plate 1. The part also becomes a ventilation part. Therefore, it can be easily attached to the syringe, and even if the presser plate is pressed during the communication operation, the proximal end opening of the syringe is not blocked by the palm.

  The obstruction prevention tool does not have to have a shape as shown in FIG. 1 and may be a syringe fitting portion having a structure in which the flange is locked by closing one side of the rectangular frame (at this time, there is a barrel stopper). You do n’t have to). Also, there is no particular limitation on whether or not they are integrally formed. For example, the presser plate and the flange receiver may be formed separately and assembled and attached to the flange.

  The rod insertion portion is not limited to a circular shape as long as the rod can be inserted into the barrel when the blocking prevention tool is attached to the flange and can be connected to the gasket.

  For example, as shown in FIG. 2, the drop-off preventing claw 14 is formed in a zigzag shape having a notch portion in a direction in which the rod contacts the drop-off preventing claw 14 when the rod is screwed with the gasket. The part is formed from the upper surface to the lower surface of the pusher plate so as to go to the center side. With this shape, when the rod is inserted into the barrel and when the rod and the gasket are screwed together, the drop-out prevention claw is pushed and spread by the rod, so the rod can be easily inserted into the barrel. In addition, the rod and the gasket can be screwed together. On the other hand, when the plunger rod is moved in the anti-screwing direction or completely pulled out, the drop-out preventing claw does not spread, so that the rod does not come off or drop off. Even if it is not a zigzag type as shown in FIG. 2, the shape is not particularly limited as long as the same effect can be obtained. In addition, although it is not necessary to provide a drop-off preventing claw, it is preferable to provide it because the above-described effect can be obtained.

  The material of the blocking prevention part is not particularly limited, and for example, polyethylene, polypropylene, polyethylene terephthalate, polycarbonate, ABS resin, stainless steel, and the like can be used.

  The use state of the obstruction prevention device of the present invention is shown in FIGS. In addition, Fig.3 (a) is a front view of an obstruction | occlusion prevention tool. As shown in FIG. 3B, with the base end of the prefilled syringe not attached with the rod facing upward, the obstruction prevention tool is attached to the flange portion of the prefilled syringe not attached with the rod. Thereafter, as shown in FIG. 4, the transfer tool is used to connect the vial and the unfilled prefilled syringe, and the pusher plate of the blockage prevention tool is pushed with the palm so that the unfilled prefilled syringe and the pallet communicate with each other. . At this time, since air flows into the barrel through the space from the vent, the gasket advances to the barrel tip side, and the solution in the barrel is quickly injected into the vial to prepare the drug.

  After the drug is prepared in the vial, the rod is inserted into the barrel from the rod insertion part, the rod and the gasket are connected to complete the plunger, the plunger is pulled up, the drug solution is returned into the syringe, and used. The prefilled syringe can be used as it is without removing the occlusion prevention tool even after the adjustment operation.

  As described above, the occlusion prevention device of the present invention can be easily attached to the flange, allows air to flow into the syringe proximal end opening, and allows quick preparation of the medicinal solution. Can be used.

The perspective view of the example of one embodiment of the obstruction | occlusion prevention tool of this invention. (A) The top view of the obstruction | occlusion prevention tool shown in FIG. (B) AA sectional drawing of Fig.2 (a), ie, sectional drawing of a fall-off prevention nail | claw. (A) The front view of the obstruction | occlusion prevention tool shown in FIG. (B) The figure of the state which mounted | wore the flange of the prefilled syringe with which the obstruction | occlusion prevention tool of FIG. 1 was not mounted | worn with a rod. The figure which shows the use condition of the obstruction | occlusion prevention tool shown in FIG.

Explanation of symbols

P Pre-filled syringe T without rod T Transfer tool V Vial 1 Press plate 11 Rod insertion part 12 Rail-shaped rib 13 Auxiliary rib 14 Fall-off prevention claw 2 Flange receiver 21 Barrel stopper 3 Side wall 4 Space 5 Ventilation part

Claims (2)

An obstruction prevention device attached to the flange of the syringe barrel,
A presser plate,
A rod insertion portion provided on the pusher plate;
A syringe fitting part provided on the lower surface side of the pusher plate so as to have a space between the pusher plate and the flange;
An obstruction prevention tool including a ventilation portion provided in a portion other than the pusher plate and communicating with the space. The rod insertion part is formed in a substantially circular hole,
Further, the rod insertion portion is provided with a drop prevention claw that protrudes in the center direction of the rod insertion portion and elastically contracts only when force is applied from the rod insertion direction and the screwing direction of the rod and the gasket. The obstruction prevention device according to claim 1.

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