JP2008297291A - Cosmetic - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a cosmetic having low stickiness, excellent in use feeling and sufficiently increasing moisture retaining property in dry term to impart smooth moisture feeling to the skin. <P>SOLUTION: The cosmetic contains galactooligosaccharide composed of 4-10 monosaccharide units and having at least one fructose residue. As the galactooligosaccharide, concretely, stachyose, verbascose, ajugose and the like, or plant extracts of Lamiaceae plants and the like are listed. <P>COPYRIGHT: (C)2009,JPO&INPIT

Description

  The present invention relates to a plant extract, a cosmetic containing the same, and a skin care method using the cosmetic.

In general, cosmetics are required to have high moisturizing performance in addition to their original effects. In other words, in skin care products that promote prevention of rough skin, improvement of rough skin, and anti-aging effects such as whitening effect and prevention of wrinkles or sagging, it is essential to impart proper moisture to the skin.・ It is very effective to fully demonstrate the effect.
Therefore, generally, a moisturizing agent having a high moisturizing performance is blended in cosmetics. Conventionally used humectants include, for example, glycerin, propylene glycol, sorbitol, maltitol, various amino acids, pyrrolidone carboxylic acid, hyaluronic acid, plant extracts and the like. However, although these moisturizing agents have high moisturizing performance, they may give a feeling of stickiness to the skin depending on the amount used, and this tends to impair the usability of cosmetics. In other words, from the viewpoint of a moisturizing agent that has both high moisturizing performance and low stickiness, it has not been fully satisfactory.

  More specifically, for example, polyhydric alcohols such as glycerin and sorbitol are relatively excellent in terms of moisturizing performance, but stickiness tends to occur when blended at a high concentration, causing a problem in usability. On the other hand, natural polysaccharide components such as hyaluronic acid have little stickiness and are relatively excellent in use feeling at the time of application, but when formulated at a high concentration in order to sufficiently enhance the moisturizing effect, the formulation will thicken on the contrary, In some cases, a sufficient moisturizing effect could not be exhibited. Therefore, there has been a demand for a moisturizing agent and a cosmetic containing the moisturizing agent that do not increase in viscosity even when the amount is large, and suppress stickiness and have excellent usability.

  Under such circumstances, it has been studied to blend oligosaccharides into cosmetics as a humectant. Here, the “oligosaccharide” is a compound obtained by dehydration condensation of about 2 to 10 monosaccharides, and various types of monosaccharide units can be selected depending on the type, number, and coupling mode of the constituent monosaccharide units. Oligosaccharides are present.

For example, Patent Document 1 describes that raffinose, which is a trisaccharide, is blended in cosmetics as a moisturizing agent. Patent Document 2 describes a galactooligosaccharide obtained by dehydration condensation of 3 to 6 monosaccharides as a humectant.
JP-A-11-322574 JP 7-330577 A

  However, the raffinose described in Patent Document 1 does not exhibit a thickening phenomenon even in the case of a high blending amount and does not impair the feeling of use due to stickiness, but is similar to the conventional natural polysaccharide component described above. In terms of moisturizing effect, it is not yet satisfactory. Similarly, although the galactooligosaccharide described in Patent Document 2 is reduced in stickiness, it is not necessarily sufficient in terms of the moisturizing effect.

  Therefore, the present invention has been made in view of the above circumstances, and is a cosmetic product that is less sticky and excellent in feeling of use, and that can sufficiently enhance the moisturizing effect during drying and give a smooth moist feeling to the skin. The purpose is to provide.

  As a result of intensive studies to solve the above problems, the present inventors have formulated galactooligosaccharide having 4 or more monosaccharide units and a specific sugar residue as a moisturizer in cosmetics. As a result, it was found that stickiness can be sufficiently suppressed, and an extremely high moisturizing effect is achieved, and the present invention has been achieved.

  That is, the cosmetic product according to the present invention contains a galactooligosaccharide having 4 to 10 monosaccharide units and having at least one fructose residue. The galactooligosaccharide preferably has a glucose residue.

Furthermore, the galactooligosaccharide has the following formula (1);
Gal- (Gal) n-Glc-Fru (1)
It is more preferable that it is represented by. In the formulae, Gal independently represents a galactose residue, Glc represents a glucose residue, Fru represents a fructose residue, and n represents an integer of 1 to 7.

  Specifically, it is preferable that the galactooligosaccharide is at least one of stachyose, verbus course, and adjugoth.

  Furthermore, the present inventors have found that galactooligosaccharide can be extracted from a specific plant at a high concentration and is useful when added to the cosmetic of the present invention. That is, it has been found that even when a galactooligosaccharide extracted from a plant of the family Lamiaceae is used, stickiness can be suppressed and moisture retention performance can be improved. In particular, it is particularly useful that the Labiatae plant belongs to the genus Stachys or Lycopus.

  Furthermore, the galactooligosaccharide preferably contains 30% by weight or more of stachyose, and the amount of the galactooligosaccharide in the cosmetic is not particularly limited, but may be 0.1 to 30% by weight in the total amount of the cosmetic. desirable. In the present invention, “wt%” is equivalent to “mass%”.

  Furthermore, according to the knowledge of the present inventor, it has been found that when galactooligosaccharide is blended with a polyhydric alcohol in a cosmetic product, the moisturizing effect is synergistically improved and the stickiness of the polyhydric alcohol is not exhibited.

  “Cosmetics” in the present invention means, as prescribed in the text of Article 2, Paragraph 3 of the Pharmaceutical Affairs Law, “to cleanse, beautify, increase the appeal, change the appearance of the human body, or to change the skin or hair. In order to keep it healthy, it is intended to be used in a manner similar to those applied to the body, such as rubbing, spreading, etc., and its action on the human body is mitigated. However, in addition to these purposes of use, those intended to be used for the purposes prescribed in Paragraph 1, Item 2 or 3 of the Pharmaceutical Affairs Law, and Article 2, Paragraph 2 of the Act It also includes quasi-drugs as defined in 1. Moreover, what is generally called "cosmetics" is also included.

According to the cosmetic product of the present invention, it is possible to provide an excellent feeling of use with little stickiness, and to sufficiently enhance the moisturizing effect during drying and to give a smooth moist feeling to the skin.
Furthermore, in addition to the moisturizing effect, the cosmetic of the present invention is effective in improving the skin barrier function, improving the external / internal stress resistance of the skin, improving the resistance to contamination of the skin, and improving the whitening of the skin.

  Hereinafter, embodiments of the present invention will be described in detail.

As described above, the cosmetic product according to the present invention contains a galactooligosaccharide having 4 to 10 monosaccharide units and having at least one fructose residue as one of essential components. Although the kind of this galactooligosaccharide is not specifically limited, following formula (1);
Gal- (Gal) n-Glc-Fru (1)
It is preferable that it is represented by these. In the formula, Gal independently represents a galactose residue, Glc represents a glucose residue, Fru represents a fructose residue, and n represents an integer of 1 to 3.

  Examples of such galactooligosaccharide include stachyose which is α-D-galactopyranosyl-α-D-galactopyranosyl-α-D-glucopyranosyl-β-D-fructofuranoside, α-D- Verbasusose, which is galactopyranosyl-α-D-galactopyranosyl-α-D-galactopyranosyl-α-D-glucopyranosyl-β-D-fructofuranoside, α-D-galactopyrano Adjugos sugars which are sil-α-D-galactopyranosyl-α-D-galactopyranosyl-α-D-galactopyranosyl-α-D-glucopyranosyl-β-D-fructofuranoside These may be used alone or in combination of two or more.

  The galactooligosaccharide used in the present invention can be obtained by a known method such as isolation and purification from soybean oligosaccharide in addition to the method described in JP-A-8-168393. What extracted from the plant of Lamiaceae) is especially preferable from the viewpoint of being very effective as a moisturizing agent together with its high yield.

  On the other hand, by the conventional manufacturing method of galactooligosaccharide, a by-product is produced and the yield of galactooligosaccharide is inherently low. In addition, soybean oligosaccharide is also known as a source of stachyose, but its stachyose content is small and it is not suitable for industrial scale production. In contrast, galactooligosaccharides extracted from Labiatae plants contain high concentrations of galactooligosaccharides, including stachyose, containing fructose residues and consisting of 4 to 10 monosaccharide units. did.

  Examples of the Labiatae plant include plants belonging to the genus Stachys or the genus Lycopus. More specifically, as plants of the genus Stachys (Stachys), Stachys tuberifera, Stachys sieboldii (chologhi), Stachys arvensis (yabuchologi); Examples include macackianus, Lycopus ramosissis (Saldahiko or Koshironet), Lycopus uniflorus, and the like. Among these, the roots of Lycopus lucidus (Shironet or Sawaran) and Stachys sieboldii (chorogi) are preferred because they are highly safe for food use. These plants may be used alone or in combination of two or more.

  As a method for extracting galactooligosaccharide from the above-mentioned Labiatae plant, for example, a known extraction method as described in JP-A-5-207900 can be used. More specifically, liquid phase extraction with water, alcohol, other organic solvents, etc., or water vapor, using the above-mentioned plant parts (leaves, flowers, stems, roots) as they are in living organisms or appropriately dried as raw materials For example, there can be exemplified a method of subjecting the obtained extract to chromatographic separation and appropriate concentration, and isolating and purifying the target galactooligosaccharide. Such isolation and purification methods are described in the Journal of the Study on Refined Sugar Technology, Vol. 38, p. 39-45 (1990), Journal of Agriculture, Forestry and Fisheries Research, Vol. 27 No. 2, p. 29-32 (2004).

  Here, the blending amount of the galactooligosaccharide in the cosmetic of the present invention is not particularly limited, preferably 0.1 to 30% by weight, more preferably 0.1 to 20% by weight, and still more preferably 1 to 10% by weight. If the blending amount is less than 0.1% by weight, the moisturizing effect tends not to be sufficiently enhanced while suppressing stickiness. On the other hand, if the blending amount exceeds 30% by weight, an effect commensurate with the increase in blending amount is obtained. It tends to be difficult to obtain.

  Furthermore, it is preferable to mix a polyhydric alcohol with the above-mentioned galactooligosaccharide in the cosmetic of the present invention. In this way, compared to the case where galactooligosaccharide and polyhydric alcohol are blended alone, in addition to the higher moisturizing effect, stickiness due to polyhydric alcohol that usually occurs is also expressed. It turned out not to.

  Although details of the mechanism by which the stickiness of polyhydric alcohol is suppressed along with the improvement of the moisturizing performance due to such a synergistic effect are not yet clear, the suppression of stickiness is about the hydroxyl group (-OH It is estimated that galactooligosaccharide interferes with the interaction between the group) and water. However, the action is not limited to this.

  The compounding quantity of the polyhydric alcohol in cosmetics is not restrict | limited, Preferably it is 0.1-30 weight%, More preferably, it is 1-20 weight%. If the blending amount is less than 0.1% by weight, the synergistic moisturizing effect due to the addition of the polyhydric alcohol tends not to be sufficiently exhibited. On the other hand, if the blending amount exceeds 30% by weight, the galacto oligo Even in the presence of sugar, the stickiness of polyhydric alcohol tends to be hardly suppressed.

  Specific examples of such polyhydric alcohols include glycerin, diglycerin, polyglycerin, ethylene glycol, diethylene glycol, triethylene glycol, polyethylene glycol, propylene glycol, dipropylene glycol, polypropylene glycol, 3-methyl-1,3- Examples include butanediol, 1,3-butylene glycol, polyethylene glycol, sugar alcohols such as sorbitol and maltitol. These may be used alone or in combination of two or more.

  The form of the cosmetic product of the present invention is not particularly limited, and is an aqueous solution system (for example, lotion), an emulsion system (for example, emulsion, cream, etc.), a powder system, an oil liquid system, a gel system, an ointment system, water -It can take a wide variety of forms such as an oil two-layer (phase) system (w / o or o / w emulsion, etc.), a water-oil-powder three-layer (phase) system, and the like. Also, its use and dosage form are not particularly limited, and examples thereof include arbitrary dosage forms used in normal cosmetics such as creams, emulsions, lotions, packs, lipsticks, foundations, jellies, ointments, films, powders, and the like. It is done.

  Furthermore, there is no restriction | limiting in particular also in the manufacturing method of the cosmetics of this invention, A conventionally well-known method can be used. For example, in the case of milky lotion or cream, the above-described galactooligosaccharide, which is a moisturizing agent, can be dissolved in an aqueous phase component together with an emulsifier, and this aqueous phase component can be mixed and emulsified with stirring into a molten oil phase component.

  Furthermore, as a base material for cosmetics, for example, animal and vegetable oils, mineral oils, ester oils, waxes, higher alcohols, fatty acids, surfactants, phospholipids, alcohols, polyhydric alcohols, water-soluble Known raw materials such as polymers, clay minerals, purified water and the like can be mentioned.

  Furthermore, in addition to the essential component galactooligosaccharide, other additive components that are usually used in cosmetics can be appropriately added to the cosmetic of the present invention as needed. Examples of such additional components include fats and oils, waxes, higher fatty acids, higher alcohols, synthetic esters, purified water, hot spring water, deep water, surfactants, cooling agents, antioxidants, ultraviolet absorbers, preservatives, Chelating agents, anti-fading agents, buffers, pigments, fragrances, skin nutrients, thickeners, blood flow promoters, bactericides, anti-inflammatory agents, cell activators, vitamins, amino acids, other humectants, keratolytic agents Etc. Various additives as exemplified in Patent Document 1 described above can also be added.

  In addition, the pH of the cosmetic of the present invention is desirably 4 to 8, preferably 4.5 to 7, from the viewpoint of obtaining sufficient efficacy and enhancing safety.

  EXAMPLES Hereinafter, although an Example demonstrates this invention further in detail, this invention is not limited to these Examples at all.

[Example 1] Production of an extract from a plant of Lamiaceae (Example 1-1)
The tuberous root of Sawaran, a Labiatae plant, was washed with water, the skin was removed and cut into an appropriate size, and then homogenized with a mixer. The obtained juice was centrifuged (8000 rpm × 15 min.), And the supernatant was collected and passed through a cation exchange resin (Diaion PK220) and an anion exchange resin (WA30) to obtain an extract. 3.5 ml was weighed out from the obtained extract and made up to 10 ml with acetonitrile to obtain analytical sample 1-1.
The galactooligosaccharide contained in the analytical sample 1-1 thus obtained was analyzed under the following conditions using high performance liquid chromatography.

Analysis conditions Column: Shodex Asahipak NH2P-50 4E (inner diameter 4.6 mm, length 250 mm)
Mobile phase: acetonitrile: water = 65: 35
Flow rate: 1.0 ml / min
Column temperature: 35 ° C
Sample injection volume: 10 μl
Detector: Differential refraction detector

  The analysis results are shown in FIG. In addition, Table 1 shows the concentration of each galactooligosaccharide in the analytical sample 1-1 calculated based on the peak area of FIG.

From Table 1, the extract of tuberous root of Lycopus lucidus, a family of Lamiaceae, includes stachyose (Gal ₂ -Glc-Fru), velvia course (Gal ₃ -Glc-Fru) and adjugous (Gal ₄ -Glc-Fru) was confirmed to be contained at a ratio of about 3: 2: 1.

(Example 1-2)
The tuberous roots of the family Lamiaceae (Stachys Sieboldii Miq) were washed with water and 5 g was ground in a mortar. To this was added 5.0 g of purified water and mixed to obtain an aqueous solution of Chorogi extract. 3.5 ml was weighed out from the obtained aqueous solution and made up to 10 ml with acetonitrile to obtain analytical sample 1-2.
The galactooligosaccharide contained in the analytical sample 1-2 thus obtained was analyzed in the same manner as in Example 1-1.

  The analysis results are shown in FIG. Table 2 shows the concentration of each galactooligosaccharide in the analytical sample 1-2 calculated based on the peak area of FIG.

  From Table 2, it was confirmed that the extract of Chorogi tuberous root, which is a Labiatae plant, contained stachyose and adjugos in a ratio of about 12: 1.

[Example 2] Production of cosmetics [Preparation of galactooligosaccharide]
(Production Example 1): Stachyose (derived from Chorogi Stachys sieboldii)
Chorogi was washed with water, cut into an appropriate size, and then homogenized with a mixer. The obtained juice was centrifuged (8000 rpm × 15 min.), The supernatant was collected, and the cation exchange resin (Diaion PK220) and the anion exchange resin (WA30) were passed through. The aqueous solution containing the obtained galactooligosaccharide was subjected to column chromatography. The fractions of stachyose were collected, concentrated by an evaporator, and dried by a spray drying method to obtain stachyose (Gal ₂ -Glc-Fru).

(Production Example 2): Belbass Course (from Sawaran Lycopus lucidus)
Sawaran tuber was washed with water, the thin skin was removed and cut into an appropriate size, and then homogenized with a mixer. The obtained juice was centrifuged (8000 rpm × 15 min.), The supernatant was collected, and the cation exchange resin (Diaion PK220) and the anion exchange resin (WA30) were passed through. The aqueous solution containing the obtained galactooligosaccharide is subjected to column chromatography, the fractions of Verbose course are collected and concentrated by an evaporator, and then dried by a spray drying method to obtain Verbose course (Gal ₃ -Glc-Fru). It was.

(Comparative Production Example): Galacto-oligosaccharide consisting of tetrasaccharides not containing fructose residues Oligomate S-HP (manufactured by Yakult Pharmaceutical Co., Ltd.) was filtered with an aqueous filter (pore size 0.45 μl), and cation exchange resin ( Diaion PK220) and anion exchange resin (WA30) were passed through. The aqueous solution containing the obtained galactooligosaccharide is subjected to column chromatography, and fractions of the tetrasaccharide galactooligosaccharide are collected and concentrated by an evaporator, and then dried by a spray drying method to give a tetrasaccharide galactooligosaccharide (Gal ₃ -Glc). )

[Preparation of cosmetics]
The cosmetic products of Examples and Comparative Examples were prepared as follows. “Numerical value%” indicates a blending amount (“wt%” with respect to the total amount of cosmetics).

<Example 2-1>
A lotion was prepared by the following formulation and production method.
(Prescription)
(1) Stachyose (Production Example 1): 3.0%
(2) Purified water: 89.47%
(3) Xanthan gum: 0.1%
(4) 1,3-butylene glycol: 3.0%
(5) Methyl benzoate: 0.2%
(6) Ethanol: 4.0%
(7) Polyoxyethylene (24 mol) polyoxypropylene (24 mol) glyceryl ether: 0.2%
(8) Fragrance: 0.03%
(Manufacturing method)
The components (1) to (5) were mixed and dissolved to obtain a mixture A. Moreover, the said components (6)-(8) were mixed and dissolved, and the mixture B was obtained. Next, while stirring the mixture A, the mixture B was added and homogenized to obtain a cosmetic product of Example 2-1.

<Example 2-2>
As a humectant, Example 2-2 was used in the same manner as Example 2-1 except that 3.0% of Verbasse course of Production Example 2 was used instead of 3.0% of Stachyose of Production Example 1. A cosmetic product was prepared.

<Example 2-3>
Example 2-1 and Example 2 except that stachyose hydrate (manufactured by Sigma Aldrich: Stachyose hydrate from Stachysferifera) 3.0% was used as the moisturizer instead of stachyose 3.0% of Production Example 1. Similarly, a cosmetic product of Example 2-3 was prepared.

<Example 2-4>
5.0% of 89.47% purified water in Example 2-1 was replaced with 5.0% glycerin (trade name “concentrated glycerin for cosmetics” manufactured by Kao Corporation), which is a polyhydric alcohol. A cosmetic product of Example 2-4 was prepared in the same manner as Example 1 except for the above.

<Example 2-5>
5.0% of 89.47% of purified water in Example 2-2 was replaced with 5.0% of glycerin (trade name “concentrated glycerin for cosmetics” manufactured by Kao Corporation) which is a polyhydric alcohol. Except for the above, cosmetics of Example 2-5 were prepared in the same manner as Example 2-2.

<Comparative Example 2-1>
Example 2 except that sucrose (manufactured by Kanto Chemical Co., Inc .: sucrose, special grade) (Glc-Fru) 3.0% was used as the moisturizer instead of stachyose 3.0% in Production Example 1. The cosmetic product of Comparative Example 2-1 was prepared in the same manner as -1.

<Comparative Example 2-2>
As a moisturizer, instead of using 3.0% stachyose in Production Example 1, raffinose (manufactured by Asahi Kasei Corporation: trade name “Oligo GGF”) (Gal-Glc-Fru) 3.0% was used, A cosmetic product of Comparative Example 2-2 was prepared in the same manner as Example 2-1.

<Comparative Example 2-3>
As a humectant, in place of 3.0% stachyose in Production Example 1, galactooligosaccharide (Gal ₃ -Glc) 3.0% consisting of a tetrasaccharide not containing a fructose residue in Comparative Production Example was used. A cosmetic product of Comparative Example 3 was prepared in the same manner as Example 2-1.

<Comparative Example 2-4>
Example 2-1 except that 3.0% glycerin (trade name “concentrated glycerin for cosmetics” manufactured by Kao Corporation) was used as a moisturizer instead of 3.0% stachyose in Production Example 1. Similarly, a cosmetic product of Comparative Example 2-4 was prepared.

<Comparative Example 2-5>
Example 2-1 except that 3.0% pyrrolidone carboxylate (manufactured by Ajinomoto Co., Inc .: trade name “PCA soda”) was used instead of 3.0% stachyose in Production Example 1 as a moisturizer. A cosmetic product of Comparative Example 2-5 was prepared in the same manner as described above.

<Comparative Example 2-6>
5.0% of 89.47% purified water of Comparative Example 2-1 was replaced with 5.0% glycerin (trade name “concentrated glycerin for cosmetics” manufactured by Kao Corporation), which is a polyhydric alcohol. A cosmetic product of Comparative Example 2-6 was prepared in the same manner as Comparative Example 2-1, except for the above.

<Comparative Example 2-7>
5.0% of 89.47% purified water in Comparative Example 2-2 was replaced with 5.0% glycerin (trade name “concentrated glycerin for cosmetics” manufactured by Kao Corporation), which is a polyhydric alcohol. A cosmetic product of Comparative Example 2-7 was prepared in the same manner as Comparative Example 2-2, except for the above.

<Comparative Example 2-8>
5.0% of 89.47% purified water of Comparative Example 2-3 was replaced with 5.0% glycerin (trade name “concentrated glycerin for cosmetics” manufactured by Kao Corporation) which is a polyhydric alcohol. Except for the above, cosmetics of Comparative Example 2-8 were prepared in the same manner as Comparative Example 2-3.

[Moisturizing effect measurement test]
The moisturizing effects of the cosmetics of Examples 2-1 to 5 and Comparative Examples 2-1 to 8 were measured as follows. First, 10 female subjects in their 20s to 50s washed their face by a normal method in a room set at a room temperature of 21 ° C. and a relative humidity of 50%, and then applied each cosmetic to their own cheeks. The skin moisture content of the cheeks of each subject after 3 hours from application was measured using CORNEOMETER CM825 (manufactured by Integral). Table 3 shows the measurement results of the skin moisture content. Moreover, the average value for every Example and Comparative Example, and the difference between the average value and the reference value (60) are also shown as “moisturizing effect”. In addition, this skin moisture content is one of the indexes showing that the greater the numerical value, the higher the moisturizing effect.

[Usability measurement test (sensory test)]
The feeling of use of the cosmetics of Examples 2-1 to 5 and Comparative Examples 2-1 to 8 was measured as follows. Each cosmetic product was applied to the hands and faces of 10 female subjects in their 20s and 50s, and the degree of skin stickiness at that time was judged sensuously. Based on the determination result, the feeling of use of each cosmetic was evaluated according to the following evaluation criteria.
(Usage evaluation criteria)
The person who evaluated that there was little stickiness,
◎: 9 or more of 10 subjects ○: 7 or 8 of 10 subjects Δ: 5 or 6 of 10 subjects ×: 4 or less of 10 subjects

  Table 4 summarizes the results of the moisturizing effect test and usability measurement test of Examples 2-1 to 5 and Comparative Examples 2-1 to 8.

  From the results shown in Table 4, it was confirmed that Examples 2-1 to 5 which are cosmetics of the present invention were superior in both moisturizing effect and feeling of use (degree of stickiness) as compared with Comparative Examples 2-1 to 8. . In addition, from the comparison between Example 2-1 using the tetrasaccharide galactooligosaccharide and Comparative Example 2-3, the galactooligosaccharide having a fructose residue is superior to the galactooligosaccharide having no fructose residue. It was confirmed to have a moisturizing effect and a feeling of use. Furthermore, from comparison between Examples 2-1 to 2-1 and Comparative Examples 2-1 and 2-2, in the galactooligosaccharide having a fructose residue, the moisturizing effect is remarkably excellent when the number of monosaccharide units is 4 or more. It became clear that the feeling of use was greatly improved.

  Furthermore, from the results of Examples 2-4 and 2-5, it was found that the moisturizing effect of the galactooligosaccharide was further improved by combining the polyalcohol with the galactooligosaccharide having a fructose residue. On the other hand, from the results of Comparative Examples 2-6 and 2-8, the synergistic effect confirmed in Examples 2-4 and 2-5 is related to other oligosaccharides (sucrose and galacto-oligosaccharides of comparative production examples). Was confirmed not to be played.

  From the above, it is understood that the cosmetic product of the present invention has almost no stickiness, which is a defect of the conventional moisturizing agent, and exhibits a very high moisturizing effect as compared with the conventional moisturizing agent.

  The cosmetic product of the present invention has an excellent feeling of use by alleviating stickiness, and since the moisturizing effect is enhanced and a smooth moist feeling can be imparted to the skin, an aqueous solution system, an emulsion system, a powder system, an oil liquid system, Cosmetics in a wide variety of forms such as gel, ointment, water-oil 2 layer (phase) system, water-oil-powder 3 layer (phase) system, and cream, emulsion, lotion, pack, lipstick, foundation, jelly It is useful as various cosmetics for use in ointments, coatings, powders and dosage forms.

Results of high-performance liquid chromatography analysis of Sawaran extract Results of high-performance liquid chromatography analysis of chologi extract

Claims (15)

  An extract from a plant of the family Lamiaceae comprising galactooligosaccharides consisting of 4 to 10 monosaccharide units and having at least one fructose residue.   The extract according to claim 1, wherein the Labiatae plant belongs to the genus Stachys or Lycopus. The galactooligosaccharide is represented by the following formula (1);
Gal- (Gal) n-Glc-Fru (1)
(Wherein, Gal independently represents a galactose residue, Glc represents a glucose residue, Fru represents a fructose residue, and n represents an integer of 1 to 7).
Which is represented by
The extract according to claim 1 or 2. The galacto-oligosaccharide is at least one of stachyose, verbus course, and adjugous,
The extract according to any one of claims 1 to 3.   A cosmetic comprising an extract from a plant of the family Lamiaceae comprising galactooligosaccharides consisting of 4 to 10 monosaccharide units and having at least one fructose residue.   The cosmetic product according to claim 5, wherein the Labiatae plant belongs to the genus Stachys or the genus Lycopus.   Cosmetics comprising galactooligosaccharides consisting of 4 to 10 monosaccharide units and having at least one fructose residue.   The cosmetic according to any one of claims 5 to 7, wherein the galactooligosaccharide has a glucose residue. The galactooligosaccharide is represented by the following formula (1);
Gal- (Gal) n-Glc-Fru (1)
(Wherein, Gal independently represents a galactose residue, Glc represents a glucose residue, Fru represents a fructose residue, and n represents an integer of 1 to 7).
Which is represented by
Cosmetics of any one of Claims 5-8. The galacto-oligosaccharide is at least one of stachyose, verbus course, and adjugous,
Cosmetics of any one of Claims 5-9. The galactooligosaccharide contains stachyose at 30% by weight or more,
Cosmetics given in any 1 paragraph of Claims 5-10. Containing 0.1 to 30% by weight of the galactooligosaccharide,
The cosmetic according to any one of claims 5 to 11. Containing 0.1 to 30% by weight of a polyhydric alcohol,
The cosmetic according to any one of claims 5 to 12.   For improving skin barrier function and / or improving skin moisture retention and / or improving skin external / internal stress tolerance and / or skin contamination resistance and / or skin whitening A skin care method comprising applying a cosmetic according to any one of claims 5 to 13 to the skin.   A skin care method for reducing or preventing stickiness caused by a polyhydric alcohol, comprising the step of applying the cosmetic according to claim 13 to the skin.

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