JP2008295833A - Long tool and treatment device to remove foreign matter from blood vessel - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a long tool and a treatment device to remove foreign matters from vessels that secures a necessary space within a blood vessel even if any external force has been applied to it and catches the foreign matter there without fail. <P>SOLUTION: A long tool 1A for removing the foreign matters from blood vessel has a long tool body 2 with a curved part 23 provided at its leading end, in addition to two wires 7a and 7b laid between the tip 231 and the base 232 of the curved part 23. In the long tool 1A to remove the foreign matters from vessels, the wires 7a and 7b crosses each other at a point 73, and a first loop 74 and a second loop 75 have been formed through this crossing 73. <P>COPYRIGHT: (C)2009,JPO&INPIT

Description

  The present invention relates to a long body for removing foreign matter in a blood vessel that removes foreign matter in a blood vessel and a medical instrument including the same.

  According to the Ministry of Health, Labor and Welfare's demographic statistics, the first cause of death in Japan is cancer, the second is heart disease, the third is stroke, and deaths and sequelae are especially urgent. It has become.

  In recent years, thrombolytic therapy using a thrombolytic agent has been developed for treating cerebral infarction in the acute phase in the treatment of stroke, and its therapeutic effect has been raised, but its limitations are also pointed out. In other words, from the experience of doctors, thrombolytic agents require a long time for thrombolysis, smaller thrombi fly further to form new emboli sites, and there are thrombi that do not dissolve with thrombolytic agents. It recognized.

  In the case of cerebral infarction, if the blood flow can be resumed within 3 hours after the onset of the infarction, not only will the survival rate increase, but it has been proved in the United States and Europe that it can be inserted into the cerebral blood vessels and directly takes a thrombus. There is a strong demand for the development of medical devices (wires for removing foreign substances in blood vessels) that can be used.

  A conventional intravascular foreign matter removing wire has a long wire main body and a capturing portion that is provided on the distal end side of the wire main body and captures a thrombus (see, for example, Patent Document 1). The trapping part is composed of two branch wire parts that branch from the tip of the wire body and three filament parts that are installed between these branch wire parts, and a foreign matter trapping space is formed inside. Yes.

  However, this intravascular foreign matter removal wire may have different branch wire portions depending on the state of the blood vessel into which the wire is inserted (for example, the size of the inner diameter), the state of the thrombus (for example, the size and shape), and the degree of bending of the blood vessel. In addition, there has been a problem that the filament capturing space may be crushed when each filament (capture) is pressed against the thrombus and the inner wall of the blood vessel. In this case, it has been difficult to store the thrombus in the foreign substance capturing space, that is, to capture the thrombus.

JP 2003-10193 A

  It is an object of the present invention to ensure a space for capturing a foreign substance in a blood vessel even when an external force is applied, and to securely remove the foreign substance in the blood vessel that can reliably capture the foreign substance in the blood vessel. And providing a medical device.

Such an object is achieved by the present inventions (1) to (13) below.
(1) a long body having a curved portion at the tip;
Comprising at least two erection wires constructed between a distal end and a proximal end of the bending portion;
The long wire for removing foreign matter in a blood vessel, wherein the erected wires intersect at least at one place, and a plurality of loops are formed through the intersecting portion.

  (2) Each erected wire is a long body for removing foreign matter in a blood vessel according to (1), which is more flexible than the bending portion.

  (3) Each erected wire is a long body for removing intravascular foreign matter according to (1) or (2), wherein the wire diameter is smaller than that of the curved portion.

  (4) The intersection is configured to be movable along the axial direction of the elongated body for removing intravascular foreign matter, and is configured such that the size of each loop changes with this movement. (1) The long body for removing a foreign substance in a blood vessel according to any one of (3).

  (5) The apparatus according to (4), wherein the adjacent loops have one loop, and when the crossing portion between them moves, one of the adjacent loops expands and the other loop contracts. Long body for removing foreign substances in blood vessels.

  (6) The long body for removing foreign matter in a blood vessel according to (4) or (5) above, having a regulating means for regulating the moving range of the intersecting portion.

  (7) The long body for removing foreign matter in a blood vessel according to (6), wherein the restriction means is configured by a restriction wire formed in a loop shape so as to surround the intersecting portion.

  (8) The elongated body for removing foreign matter in blood vessel according to (7), wherein the restriction wire has a function of preventing the foreign matter in the blood vessel taken into the curved portion from being detached.

  (9) When the long body for removing foreign matter in blood vessel is viewed from the distal end side, an angle formed between the distal end portions of the adjacent erected wires is 90 to 180 °. (1) to (8) The long body for removing a foreign substance in a blood vessel according to any one of the above.

  (10) When the surfaces having the respective loops as contours are assumed, the adjacent surfaces have mutually different normal directions, and the intravascular foreign matter removing device according to any one of (1) to (9) above Long body.

  (11) When capturing a foreign substance in a blood vessel, the intersection is separated to form one opening, and the foreign substance is taken into the curved part from the opening. A long body for removing foreign substances in blood vessels according to claim 1.

  (12) The long body for removing foreign matter in a blood vessel according to any one of (1) to (11), wherein the curved portion is curved in an arc shape.

(13) The long body for removing a foreign substance in a blood vessel according to any one of (1) to (12) above,
A medical instrument comprising a catheter having a lumen capable of accommodating the long body for removing foreign matter in a blood vessel.

  According to the present invention, since a plurality of loops are formed through the crossing portion, an external force is applied in such a direction that, for example, one or more of these loops contracts the loops. Even in such a state, the loop to which the external force is applied is prevented from being contracted (collapsed). As a result, a space for capturing the foreign matter in the blood vessel is reliably ensured, and thus the foreign matter can be reliably captured in the space.

  In addition, when the crossing portion moves, when one of the adjacent loops expands and the other loop contracts, for example, a long body for removing intravascular foreign matter is inserted into the blood vessel. In this case, even if the other loop is pressed and contracted by the blood vessel wall, the one loop expands, so that the space for capturing the foreign matter in the blood vessel is reliably prevented from being crushed. Can be maintained (secured). Thereby, the said foreign material can be more reliably supplemented.

  Hereinafter, the long body for removing a foreign substance in a blood vessel and a medical instrument of the present invention will be described in detail based on preferred embodiments shown in the accompanying drawings.

<First Embodiment>
FIG. 1 is a perspective view showing a first embodiment of a long body for removing intravascular foreign matter according to the present invention, and FIG. 2 is a view of the long body for removing intravascular foreign body shown in FIG. FIG. 3 is a view of the long body for removing intravascular foreign matter shown in FIG. 1 as viewed from the arrow B side, and FIGS. 4 and 5 are views of the capturing part in the long body for removing foreign body intravascular blood shown in FIG. FIGS. 6 to 10 are diagrams for explaining the process of using the elongated intravascular foreign body removal body shown in FIG. 1 in order. In the following description, for convenience of explanation, the upper side in FIGS. 1 and 3 to 5 (the same applies to FIGS. 11 to 15) is referred to as the “front end” and the lower side is referred to as the “base end”, and FIGS. The left side is called the “tip” and the right side is called the “base”.

  An elongated intravascular foreign body 1A shown in FIG. 1 captures and removes foreign substances (hereinafter referred to as “emboli”) that cause embolization such as blood clots and blood clots in the blood vessel 100. .

  This long body for removing foreign matter in blood vessel (wire for removing foreign matter in blood vessel) 1A is installed on a long body main body (wire main body) 2 and a curved portion 23 positioned at the distal end of the long body main body 2. It has two erection wires 7a and 7b. Moreover, in the long body 1A for removing a foreign substance in a blood vessel, the capturing part 3 is configured by the bending part 23 and the erection wires 7a and 7b. A foreign substance capturing space 31 capable of capturing (accommodating) the embolus 200 in the blood vessel 100 is formed inside the capturing section (foreign substance capturing section) 3. Hereinafter, the configuration of each unit will be described.

  The long body 2 has moderate rigidity and elasticity (flexibility) over the entire length. The structure of the long body 2 is not particularly limited as long as it is long. For example, it is composed of a single wire, a bundle of a plurality of wires, a hollow structure, a tubular structure, or a multilayer structure. Further, a material having a core material and a coil wound around the outer periphery thereof, a combination thereof, or the like may be used. In this embodiment, a wire is shown as a specific example of the long body.

  Moreover, it does not specifically limit as a constituent material of the elongate body main body 2, For example, various metal materials like stainless steel, various plastics, etc. can be used individually or in combination.

Hereinafter, the example which is a wire is demonstrated as a specific example of an elongate body.
The elongate body 2 is located on the proximal end side, the relatively hard first part, the distal part, the relatively flexible third part, the first part, and the third part. And a second portion where the flexibility changes. In other words, the elongate body 2 is preferably such that the rigidity (bending rigidity, torsional rigidity, etc.) gradually decreases from the proximal end toward the distal end. As a result, the operation at hand is reliably transmitted to the distal end portion, the running property within the blood vessel 100 and the operability at the bent portion are excellent, the flexibility of the distal end portion is improved, and the blood vessel 100 is prevented from being damaged. Can do. That is, it is possible to ensure higher safety while maintaining the torque transmission performance, pushability (pushability), and kink resistance (bending resistance) of the long body 2.

  The outer surface (surface) of the long body 2 may be provided with a coating layer that reduces frictional resistance with the inner surface of the catheter 8 described later. Thereby, insertion and extraction with respect to the catheter (microcatheter) 8 can be performed more smoothly. Examples of the coating layer include a coating layer of a fluorine resin such as polytetrafluoroethylene, and a hydrophilic polymer coat having lubricity when wet.

  The elongated body 2 has a curved portion 23 at the tip. The curved portion 23 is a portion that is curved in one direction toward the outside, that is, has an arch shape (arc shape). Since the curved portion 23 has such a shape, the size of the capturing portion 3 (foreign matter capturing space 31) can be set as large as possible. Therefore, when the embolus 200 is captured by the capturing portion 3. The operation can be easily performed.

  Moreover, the curved part 23 is formed using the two linear bodies (wires) 6 in this embodiment. These linear bodies 6 are twisted halfway and gathered together to form a stranded portion, and a curved portion 23 is constituted by the stranded portion. Since the curved portion 23 is formed of a stranded wire portion, the shape of the capturing portion 3 can be maintained even when an external force is applied to the capturing portion 3, and thus easily and reliably in the foreign matter capturing space 31. The embolus 200 can be captured. Here, examples of the “external force” include a pressing force from a wall portion (blood vessel wall) of the blood vessel 100.

  The portion from the stranded wire portion (curved portion 23) of the two linear bodies 6 is branched into two to form one linear body 6, and the end portions ( The base end portions are respectively fixed to the base end side (long body main body 2) of the bending portion 23 (see FIG. 1). The fixing method is not particularly limited. For example, the end (base end) of each linear body 6 is knitted (wrapped) around the long body body 2, brazing, welding, bonding with an adhesive, or the like. It can be fixed by applying. Further, the long body body 2 is provided with a coil 21 that covers a fixing portion (brazing portion) of each linear body 6 with respect to the long body body 2. The outer surface of the coil 21 is smooth, and thereby higher safety is obtained.

  Each of the linear bodies 6 thus fixed constitutes two erected wires 7 a and 7 b that are laid between the distal end 231 and the proximal end 232 of the bending portion 23.

  In addition, although the wire diameter of each linear body 6 is not specifically limited, when each linear body 6 is comprised with the alloy which shows a superelasticity in the living body mentioned later, respectively, it is 0.06-0.1 mm, for example. Preferably, it is 0.06-0.08 mm.

  As shown in FIG. 1 (the same applies to FIGS. 2 to 10), the erected wire 7a and the erected wire 7b are each curved in a substantially S shape and are in a mirror image relationship with each other. For this reason, the construction wire 7a and the construction wire 7b intersect at one place. In the capturing part 3, a first loop 74 located on the distal end side and a second loop 75 located on the proximal end side are formed via an intersection (intersection) 73 between the construction wire 7 a and the construction wire 7 b. Has been. The crossing portion 73 is a portion where the erection wire 7a and the erection wire 7b appear to intersect each other in plan view (the direction in which the erection wire 7a and the erection wire 7b are viewed from the right to the left in FIG. 2 or 3). Yes, the erected wires 7a and 7b may be in contact with each other, or a slight gap may be formed between them. Further, each of the erection wires 7 a and 7 b does not intersect with the bending portion 23, and has a total length longer than that of the bending portion 23. Further, the curvatures of the construction wires 7a and 7b are respectively larger than the curvature of the bending portion 23.

  In other words, the erected wire 7a and the erected wire 7b are close to each other at the intersection 73 in a natural state (a state where no external force is applied). The intersecting portion 73 is formed by the construction wire 7a and the construction wire 7b being in contact with each other, or the construction wire 7a and the construction wire 7b are substantially in contact with each other. On the other hand, in a natural state, the erection wire 7a and the erection wire 7b are not close to the bending portion 23 in the middle thereof. Therefore, the erection wire 7a and the erection wire 7b do not form an intersection 73 with the bending portion 23, respectively. Therefore, the erection wire 7a and the erection wire 7b are in the middle of the long body main body. The second curved portion 23 is not in contact with or almost in contact with the curved portion 23.

  The erection wire 7a and the erection wire 7b have a shape of “8”. The erected wire 7a and the erected wire 7b form a shape in which the first loop 74 and the second loop 75 look like a numeral “8” through one intersection 73 in plan view. This “8” shape has a first loop 74, a second loop 75, and an intersection 73.

  The erected wire 7a and the erected wire 7b have a shape (twisted loop shape) formed when one end of the loop is twisted by 180 ° with both ends of a single loop. At this time, two loops are formed from a single loop, and these two loops are connected via one intersection 73. The loop shape composed of the erection wire 7a and the erection wire 7b has a first loop 74, a second loop 75, and an intersection 73 in plan view.

  In this way, the first loop 74 and the second loop 75 are connected in the form of a loop so that, for example, one or both of these loops contracts the loop. Even if an external force is applied (in the vertical direction in FIG. 2), the first loop 74 and the second loop 75 are prevented from contracting (collapsing). Thereby, the foreign substance capture space 31 is reliably ensured, and accordingly, the embolus 200 can be reliably captured in the foreign substance capture space 31.

  Moreover, the crossing part 73 is located in the approximate center part of the construction wire 7a in the natural state (the construction wire 7b is also the same). Therefore, in the natural state, the sizes of the first loop 74 and the second loop 75 are substantially equal. Here, the “natural state” refers to a state where no external force is applied. In addition, the distance m from the front-end | tip (the front-end | tip 231 of the bending part 23) of the capture | acquisition part 3 of the cross | intersection part 73 is not limited to the half (0.5L) of the length (string length) L of the bending part 23 in a natural state. For example, it is preferable that it is 0.3L-0.7L, and it is more preferable that it is 0.4L-0.5L.

  Further, as described above, the bending portion 23 is formed by twisting two linear bodies 6, and each of the erected wires 7 a and 7 b is composed of one linear body 6. ing. Therefore, each of the erected wires 7 a and 7 b has a smaller diameter than the bending portion 23 and is more flexible than the bending portion 23. Accordingly, when the embolus 200 is captured, the erected wires 7a and 7b are preferentially deformed over the curved portion 23, and the embolus 200 is easily inserted into the foreign matter capturing space 31 from between the erected wires 7a and 7b. (See FIG. 9).

  As shown in FIG. 4 (a), the intersection of the construction wire 7b and the portion of the construction wire 7a on the proximal side relative to the intersection 73, that is, the loop constituting portion 752 constituting the second loop 75 of the construction wire 7a and the construction wire 7b. External force was applied in a direction closer to the portion closer to the base end than the portion 73, that is, the loop constituting portion 753 constituting the second loop 75 of the erection wire 7b (arrow C direction in FIG. 4A). At this time, the intersecting portion 73 is displaced (moved) in the proximal direction (the direction of arrow D in FIG. 4A) along the wire axis direction. Thereby, as shown in FIG. 4B, the second loop 75 contracts, and the first loop 74 expands accordingly.

  Similarly to this, as shown in FIG. 5A, a portion on the tip side of the crossing portion 73 of the erection wire 7a, that is, a loop constituting portion 742 constituting the first loop 74 of the erection wire 7a, A direction in which the portion on the tip side of the crossing portion 73 of the installation wire 7b, that is, the loop constituting portion 743 constituting the first loop 74 of the installation wire 7b approaches each other (the direction of arrow E in FIG. 5A). When an external force is applied to the crossing portion 73, the intersecting portion 73 is displaced (moved) in the distal direction (in the direction of arrow F in FIG. 5A) along the wire axis direction. As a result, as shown in FIG. 5B, the first loop 74 contracts, and the second loop 75 expands accordingly.

  When the capturing unit 3 has such a configuration, for example, when the elongated intravascular foreign body removal body 1 </ b> A (capturing unit 3) is inserted into the blood vessel 100, the first loop 74 and the second loop 75. Even if one of the loops is pressed by the blood vessel wall and contracts, the other loop expands, so that the entire capture unit 3 is reliably prevented from being crushed, and the size of the capture unit 3 (foreign material capture space 31) is increased. Can be maintained (secured). Thereby, the embolus 200 can be supplemented more reliably.

  Further, as described above, each of the erection wires 7a and 7b is more flexible than the bending portion 23. Therefore, the erection wires 7a and 7b are easily deformed, that is, the intersecting portion 73 is formed. It can be moved easily.

  Similarly, since the construction wires 7a and 7b are more flexible than the bending portion 23, even if the sizes of the first loop 74 and the second loop 75 are changed, the bending wires 23a and 7b are curved. The change in the length L of the portion 23 itself is suppressed (or prevented). Thereby, the magnitude | size of the capture | acquisition part 3 can be ensured more reliably, and, therefore, the embolus 200 can be reliably accommodated in the said capture | acquisition part 3. FIG.

  As shown in FIG. 2, when the intravascular foreign matter removing elongated body 1 </ b> A is viewed from the distal end side, the angle α formed near the distal end portion 71 between the erected wires 7 a and 7 b is preferably 90 to 180 °. 90 to 120 ° is more preferable. The bending portion 23 is disposed at an equiangular position with respect to the distal end portion 71 of the erection wire 7a and the distal end portion 71 of the erection wire 7b when the elongated body 1A for removing foreign substances in blood vessels is viewed from the distal end side. ing.

  With such an arrangement, the size of the foreign material capturing space 31 can be set as large as possible, and thus the embolus 200 can be easily accommodated in the foreign material capturing space 31.

  Further, when assuming surfaces having the first loop 74 and the second loop 75 as outlines, these surfaces are not located on the same surface, that is, the directions of the normal lines 741 and 751 are It is different (see FIG. 3). Thereby, compared with the case where it is located on the same surface, the contact area of the construction wires 7a and 7b and the blood vessel becomes smaller, and the blood vessel damage by the construction wires 7a and 7b can be suppressed. The angle β formed between the normal lines 741 and 751 is not particularly limited, but is preferably, for example, 5 to 90 °, and more preferably 20 to 45 °.

  Moreover, although it does not specifically limit as a constituent material of the construction wires 7a and 7b and the bending part 23 (capturing part 3), For example, the alloy which shows super elasticity in the living body is preferable. Thereby, for example, when the elongated body 1A for removing intravascular foreign matter is accommodated in the catheter 8, the capturing unit 3 is in a folded state (contracted state). When projecting, deformation to the state shown in FIG. 1 (expanded state) can occur more reliably, and a more accurate restored shape can be obtained in the expanded state. In addition, the size of the capturing unit 3 (foreign material capturing space 31) can be more reliably maintained even when an external force is applied.

  Here, an alloy exhibiting superelasticity in a living body is almost in its original shape even if it is deformed (bent, pulled, compressed) to a region where normal metal undergoes compositional deformation at least at a living body temperature (around 37 ° C.). It has a property of recovering and is also called a shape memory alloy, a super elastic alloy, or the like. Although it does not specifically limit as a shape memory alloy and a superelastic alloy, For example, a titanium type (Ti-Ni, Ti-Pd, Ti-Nb-Sn, etc.) and a copper type alloy are preferable.

  The medical instrument 9 of the present invention has such a long body 1A for removing foreign matter in blood vessels and a catheter 8.

  Next, an example of a method for using the elongated intravascular foreign body removal body 1A (medical instrument 9) of the present invention will be described in detail.

  [1] FIG. 6 shows a state where an embolus 200 such as a thrombus is clogged in the blood vessel 100 and the blood flow is inhibited. The embolus 200 is pressed against the inner wall of the blood vessel 100 by blood pressure and is not easily moved.

  A catheter (microcatheter) 8 and a guide wire 10 inserted into the lumen are inserted into the blood vessel 100, and the distal end portion 101 of the guide wire 10 protruding from the distal end opening 81 of the catheter 8 is embolized 200. Insert deeper (peripheral side). In other words, the distal end portion 101 of the guide wire 10 passes through the gap between the embolus 200 and the inner wall of the blood vessel 100 and exceeds the embolus 200. This operation can be performed more easily by using, for example, a micro guide wire having excellent lubricity as the guide wire 10.

  [2] When the distal end portion 101 of the guide wire 10 exceeds the embolus 200, the catheter 8 is advanced relative to the guide wire 10, and the distal end portion of the catheter 8 is moved to the embolus 200 and the inner wall of the blood vessel 100 as shown in FIG. 7. Get into the gap. At this time, since the distal end portion of the catheter 8 smoothly enters the gap along the guide wire 10, this operation can be easily performed.

  As a conventional treatment, a thrombolytic agent is flowed retrogradely through the catheter 8 in this state to speed up the thrombolysis. Long hours are often experienced by physicians. The present invention is also useful in such a case.

  [3] From the state shown in FIG. 7, the guide wire 10 is removed, and the long body 1 </ b> A for removing intravascular foreign matter of the present invention is inserted into the lumen of the catheter 8. As shown in FIG. 8, the capturing part 3 is protruded from the distal end opening 81 of the catheter 8 and the catheter 8 is pulled in the proximal direction.

  The capturing part 3 in the catheter 8 in the contracted state automatically expands due to its own elasticity and enters an expanded state. When the capturing unit 3 is in the expanded state, a foreign matter capturing space 31 for capturing the embolus 200 is formed. At this time, as described above, the foreign substance capturing space 31 is reliably ensured even in a state (not shown) where the capturing unit 3 is pressed against the inner wall of the blood vessel 100 at the bent part of the blood vessel.

  [4] After the foreign matter capturing space 31 is formed (secured), the intravascular foreign matter removal elongated body 1A is moved in the proximal direction, that is, the intravascular foreign matter removal elongated body 1A is embolized 200. Pull back to the front. At this time, as shown in FIG. 9, the embolus 200 enters between the erected wire 7a and the erected wire 7b, that is, in the vicinity of the intersection 73, and the erected wire 7a and the erected wire 7b ( The intersection 73) is separated. Thereby, one opening 76 is formed between the erection wire 7 a and the erection wire 7 b, and the embolus 200 starts to enter the foreign substance capturing space 31 through the opening 76. When the intravascular foreign matter removing elongate body 1A is further pulled in the proximal direction, the embolus 200 is scooped into the foreign matter catching space 31 of the catching portion 3 as shown in FIG. ) At this time, the erected wire 7a and the erected wire 7b are restored in shape due to their own elasticity and come into contact again (intersection 73 is formed), and the first loop 74 and the second loop 75 are formed again. .

  [5] When the embolus 200 is stored in the capturing unit 3, the elongated body 2 is pulled in the proximal direction with respect to the catheter 8. Accordingly, the proximal end portions of the bending portion 23 and the erection wires 7a and 7b are respectively brought into contact with the distal end opening portion 81 (the edge portion thereof), and are drawn into the catheter 8 while narrowing each other. Thereby, the embolus 200 is fastened by the bending part 23 and the construction wires 7a and 7b.

  With this tightening force, a soft thrombus such as fibrin can be crushed and the blockage of the blood vessel 100 can be eliminated. The embolus 200 that is not crushed is more reliably held by the capture unit 3 by this tightening force, and can be reliably recovered while preventing the detachment (detachment) from the capture unit 3.

  [6] The long body 1A for removing a foreign substance in a blood vessel is removed together with the catheter 8 while maintaining the tightened state. As a result, the embolus 200 is recovered (removed) in the parent guiding catheter or sheath introducer (not shown).

  In [4], when the embolus 200 is stored in the foreign substance capturing space 31, the operation (storage operation) is performed between the erection wire 7a and the erection wire 7b (opening 76). For example, the operation may be performed between the erection wire 7a (or the erection wire 7b) and the bending portion 23, or via the second loop 75 (or the first loop 74). The operation may be performed.

  Further, when the embolus 200 is stored in the capturing part 3 without performing the tightening operation of [5], the intravascular foreign matter removing elongated body 1A is removed together with the catheter 8 to remove the embolus 200. May be.

Second Embodiment
FIG. 11 is a perspective view showing a second embodiment of the long body for removing foreign matter in a blood vessel of the present invention.

  Hereinafter, the second embodiment of the elongated intravascular foreign body removal device and the medical device according to the present invention will be described with reference to this figure. However, the difference from the above-described embodiment will be mainly described, and the same matters will be described. The description is omitted.

  The present embodiment is the same as the first embodiment except that the number of loops formed in the capturing part is different.

  In the long body 1B for removing foreign matter in a blood vessel shown in FIG. 11, the erected wire 7a and the erected wire 7b intersect at one more place in addition to the intersecting portion 73. As a result, a third loop 78 is further formed on the proximal end side of the second loop 75 via the intersection 77 between the erection wire 7a and the erection wire 7b.

  Moreover, when assuming the surface which makes the 1st loop 74, the 2nd loop 75, and the 3rd loop 78 each contour, these surfaces are not located on the same surface, ie, normal lines Are preferably in different directions.

  In the elongated intravascular foreign body removal body 1B having such a configuration, the size of each loop is smaller than the size of each loop described in the first embodiment, and accordingly, a relatively small embolus 200 is captured. Can do. In addition, the increased number of crossing portions makes it easier for the embolus 200 (thrombus) to be entangled, and there is an advantage that the embolus 200 can be stably recovered.

<Third Embodiment>
FIG. 12 is a perspective view showing a third embodiment of the long body for removing foreign matter in a blood vessel of the present invention.

  Hereinafter, the third embodiment of the elongated body for removing intravascular foreign matter and the medical device of the present invention will be described with reference to this figure. However, the difference from the above-described embodiment will be mainly described, and the same matters will be described. The description is omitted.

  This embodiment is the same as the first embodiment except that the number of installation wires is different.

  In the elongated body 1C for removing foreign matter in a blood vessel shown in FIG. 12, erection wires 7 a, 7 b and 7 c are erected on the bending portion 23. The erection wire 7a, the erection wire 7b, and the erection wire 7c intersect each other at one place, and one intersection 73 is formed. As a result, three loops, that is, a loop 79a composed of the erection wire 7a and the erection wire 7b, the erection wire 7b, and the erection wire 7c are respectively provided on the distal end side and the proximal end side via the intersection 73. And a loop 79c composed of the erection wire 7a and the erection wire 7c.

  In the intravascular foreign matter removing elongated body 1C having such a configuration, the arrangement density of the erection wires 7a to 7c is higher than the arrangement density of the erection wires 7a and 7b of the first embodiment, and is therefore relatively small. The embolus 200 can be captured. In addition, when the wire diameter of one of the erected wires 7a, 7b, and 7c is smaller than that of the other wires, the thin wire is connected to the embolus 200 (thrombus). In contact, it deforms more flexibly, the emboli 200 is more easily entangled, and the performance in collecting the emboli 200 is enhanced.

  The erection wire 7a, the erection wire 7b, and the erection wire 7c are not limited to crossing each other at one place, and may cross at a plurality of places.

<Fourth embodiment>
FIG. 13 is a perspective view showing a fourth embodiment of the long body for removing foreign matter in a blood vessel of the present invention, and FIGS. 14 and 15 are views of a capturing part in the long body for removing foreign matter in a blood vessel shown in FIG. It is a figure which shows a deformation | transformation process.

  Hereinafter, the fourth embodiment of the elongated intravascular foreign body removal device and the medical device according to the present invention will be described with reference to these drawings. However, the difference from the above-described embodiment will be mainly described, and similar matters will be described. Will not be described.

  The present embodiment is the same as the first embodiment except that it further includes a regulation wire (regulation means).

  The intravascular foreign matter removal elongate body 1D shown in FIG. 13 (similarly in FIGS. 14 and 15) has a regulating wire 5 as a regulating means for regulating the movement range of the intersecting portion 73. The restriction wire 5 has flexibility, and one end 51 of the restriction wire 5 extends from the middle of the curved portion 23 (in the illustrated configuration, the central portion), and forms a loop so as to straddle (enclose) the intersecting portion 73. . Further, the other end 52 of the restriction wire 5 is fixed at substantially the same position as the one end 51 of the bending portion 23.

  As shown in FIG. 14, when the intersecting portion 73 moves in the distal direction, the restriction wire 5 is caught by the portion on the distal end side of the second loop 75. At this time, the tension F <b> 1 generated in the restriction wire 5 and the force F <b> 2 that the intersecting portion 73 tries to move in the distal direction are balanced. Thereby, it is possible to prevent the crossing portion 73 from excessively moving in the distal direction, and accordingly, the first loop 74 is extremely contracted and the second loop 75 is extremely expanded. It can be surely prevented.

  Further, as shown in FIG. 15, when the intersecting portion 73 moves in the proximal direction, the restriction wire 5 is caught by the proximal end portion of the first loop 74. At this time, the tension F <b> 1 generated in the restriction wire 5 and the force F <b> 2 at which the intersecting portion 73 tries to move in the proximal direction are balanced. Thereby, it is possible to prevent the crossing portion 73 from excessively moving in the proximal direction, so that the first loop 74 is extremely expanded or the second loop 75 is extremely contracted. Can be reliably prevented.

  In the intravascular foreign matter removal elongate body 1D, the length of the first loop 74 and the second loop 75 when the crossing portion 73 reaches the movement limit is set by appropriately setting the total length of the restriction wire 5. The ratio can be set to be, for example, 2: 8 to 8: 2.

  In addition, when the embolus 200 is captured, the restriction wire 5 assists the capture, that is, supports the embolus 200 from the outside and prevents the embolus 200 from being detached from the capturing unit 3. Demonstrate the function to do.

  Although it does not specifically limit as a constituent material of the control wire 5, For example, the alloy which shows super elasticity in the living body like the construction wires 7a and 7b can be mentioned.

  As mentioned above, although the elongate body for intravascular foreign body removal and medical instrument of this invention were demonstrated about embodiment of illustration, this invention is not limited to this, The elongate body for intravascular foreign body removal and medical instrument Each component constituting the can be replaced with any component that can exhibit the same function. Moreover, arbitrary components may be added.

  Moreover, the long body for removing a foreign substance in a blood vessel and the medical instrument of the present invention may be a combination of any two or more configurations (features) of the above embodiments.

  For example, the intravascular foreign matter removal elongate body of the second embodiment and the intravascular foreign matter removal elongate body of the third embodiment further include a restriction wire similar to that of the fourth embodiment. Also good.

Moreover, the number of installation wires installed in the long body for removing foreign matter in blood vessels of the second embodiment is as follows:
Three or four or more may be used as in the third embodiment.
Further, the number of curved portions formed is not limited to one, and may be, for example, a plurality.

It is a perspective view which shows 1st Embodiment of the elongate body for intravascular foreign material removal of this invention. It is the figure which looked at the elongate body for intravascular foreign body removal shown in FIG. 1 from the arrow A side. It is the figure which looked at the elongate body for intravascular foreign body removal shown in FIG. 1 from the arrow B side. It is a figure which shows the deformation | transformation process of the capture part in the elongate body for intravascular foreign body removal shown in FIG. It is a figure which shows the deformation | transformation process of the capture part in the elongate body for intravascular foreign body removal shown in FIG. It is a figure for explaining the usage method of the elongate body for intravascular foreign body removal shown in FIG. 1 later on. It is a figure for explaining the usage method of the elongate body for intravascular foreign body removal shown in FIG. 1 later on. It is a figure for explaining the usage method of the elongate body for intravascular foreign body removal shown in FIG. 1 later on. It is a figure for explaining the usage method of the elongate body for intravascular foreign body removal shown in FIG. 1 later on. It is a figure for explaining the usage method of the elongate body for intravascular foreign body removal shown in FIG. 1 later on. It is a perspective view which shows 2nd Embodiment of the elongate body for intravascular foreign material removal of this invention. It is a perspective view which shows 3rd Embodiment of the elongate body for intravascular foreign material removal of this invention. It is a perspective view which shows 4th Embodiment of the elongate body for intravascular foreign material removal of this invention. It is a figure which shows the deformation | transformation process of the capture part in the elongate body for intravascular foreign body removal shown in FIG. It is a figure which shows the deformation | transformation process of the capture part in the elongate body for intravascular foreign body removal shown in FIG.

Explanation of symbols

1A, 1B, 1C, 1D Long body for removing foreign matter in blood vessel (wire for removing foreign matter in blood vessel)
2 Long body (wire body)
21 Coil 23 Curved part 231 Tip 232 Base 3 Trapping part (foreign matter trapping part)
31 Foreign matter capture space 5 Restriction wire 51 One end 52 The other end 6 Linear body (wire)
7a, 7b, 7c Construction wire 71 Tip portion 73 Intersection (intersection)
74 First loop 741 Normal line 742, 743 Loop component 75 Second loop 751 Normal line 752, 753 Loop component 76 Opening 77 Intersection 78 Third loop 79a, 79b, 79c Loop 8 Catheter (microcatheter)
81 distal end opening 9 medical instrument 10 guide wire 101 distal end 100 blood vessel 200 embolus F1 tension F2 force L length (string length)
m Distance α, β Angle

Claims (13)

A long body having a curved portion at the tip, and
Comprising at least two erection wires constructed between a distal end and a proximal end of the bending portion;
The long wire for removing foreign matter in a blood vessel, wherein the erected wires intersect at least at one place, and a plurality of loops are formed through the intersecting portion.   The long body for removing foreign matter in a blood vessel according to claim 1, wherein each of the erected wires is more flexible than the curved portion.   The long body for removing intravascular foreign matter according to claim 1 or 2, wherein each of the erected wires has a smaller diameter than the curved portion.   The crossing portion is configured to be movable along an axial direction of the elongated body for removing foreign matter in a blood vessel, and the size of each loop is changed in accordance with the movement. 4. A long body for removing intravascular foreign matter according to any one of 3 above.   The intravascular foreign matter removal according to claim 4, comprising the adjacent loops, wherein one of the adjacent loops expands and the other loop contracts when the intersection between them moves. Long body.   The long body for removing foreign matter in a blood vessel according to claim 4 or 5, further comprising a restricting means for restricting a moving range of the intersecting portion.   The long body for removing a foreign substance in a blood vessel according to claim 6, wherein the regulating means is constituted by a regulating wire formed in a loop shape so as to surround the intersecting portion.   The long body for removing foreign matter in a blood vessel according to claim 7, wherein the restriction wire has a function of preventing the foreign matter in the blood vessel taken into the curved portion from being detached.   The blood vessel according to any one of claims 1 to 8, wherein when the elongated body for removing foreign matter in blood vessel is viewed from the distal end side, an angle formed between the distal end portions of the adjacent erected wires is 90 to 180 °. Long body for removing foreign matter.   10. The long body for removing intravascular foreign matter according to claim 1, wherein when the surfaces having the respective loops as contours are assumed, the adjacent surfaces have different normal directions.   The intravascular portion according to any one of claims 1 to 10, wherein when the foreign matter in the blood vessel is captured, the intersecting portion is separated to form one opening, and the foreign matter is taken into the curved portion from the opening. Long body for removing foreign matter.   The long body for removing foreign matter in a blood vessel according to any one of claims 1 to 11, wherein the curved portion is curved in an arc shape. An elongated body for removing intravascular foreign matter according to any one of claims 1 to 12,
A medical instrument comprising a catheter having a lumen capable of accommodating the long body for removing foreign matter in a blood vessel.

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