JP2008191147A - 光学キャビティデバイス及び光学キャビティ出力光を感光する方法 - Google Patents
光学キャビティデバイス及び光学キャビティ出力光を感光する方法 Download PDFInfo
- Publication number
- JP2008191147A JP2008191147A JP2008017985A JP2008017985A JP2008191147A JP 2008191147 A JP2008191147 A JP 2008191147A JP 2008017985 A JP2008017985 A JP 2008017985A JP 2008017985 A JP2008017985 A JP 2008017985A JP 2008191147 A JP2008191147 A JP 2008191147A
- Authority
- JP
- Japan
- Prior art keywords
- cavity
- analyte
- output light
- intensity
- specimen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000003287 optical effect Effects 0.000 title claims abstract description 81
- 238000000034 method Methods 0.000 title claims abstract description 27
- 239000012491 analyte Substances 0.000 claims description 71
- 238000001514 detection method Methods 0.000 claims description 43
- 230000005540 biological transmission Effects 0.000 claims description 39
- 230000006870 function Effects 0.000 claims description 26
- 238000009826 distribution Methods 0.000 claims description 21
- 230000004044 response Effects 0.000 claims description 6
- 230000008859 change Effects 0.000 abstract description 19
- 238000010586 diagram Methods 0.000 abstract description 7
- 239000000470 constituent Substances 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 description 47
- 239000012530 fluid Substances 0.000 description 35
- 238000010521 absorption reaction Methods 0.000 description 31
- 239000011521 glass Substances 0.000 description 13
- 238000000862 absorption spectrum Methods 0.000 description 9
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 7
- 239000006185 dispersion Substances 0.000 description 7
- 230000000694 effects Effects 0.000 description 7
- 239000008103 glucose Substances 0.000 description 7
- 238000000411 transmission spectrum Methods 0.000 description 7
- 238000000018 DNA microarray Methods 0.000 description 6
- 238000005259 measurement Methods 0.000 description 6
- 239000002245 particle Substances 0.000 description 6
- 230000035945 sensitivity Effects 0.000 description 6
- 206010028980 Neoplasm Diseases 0.000 description 5
- 201000011510 cancer Diseases 0.000 description 5
- 238000005286 illumination Methods 0.000 description 5
- 238000002310 reflectometry Methods 0.000 description 5
- 239000000443 aerosol Substances 0.000 description 4
- 239000011248 coating agent Substances 0.000 description 4
- 238000000576 coating method Methods 0.000 description 4
- 230000033001 locomotion Effects 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 230000007246 mechanism Effects 0.000 description 4
- 238000005070 sampling Methods 0.000 description 4
- 125000006850 spacer group Chemical group 0.000 description 4
- 238000001228 spectrum Methods 0.000 description 4
- JBRZTFJDHDCESZ-UHFFFAOYSA-N AsGa Chemical compound [As]#[Ga] JBRZTFJDHDCESZ-UHFFFAOYSA-N 0.000 description 3
- 229910001218 Gallium arsenide Inorganic materials 0.000 description 3
- 210000003722 extracellular fluid Anatomy 0.000 description 3
- 239000007789 gas Substances 0.000 description 3
- 230000010354 integration Effects 0.000 description 3
- 230000003993 interaction Effects 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 238000012544 monitoring process Methods 0.000 description 3
- 239000000758 substrate Substances 0.000 description 3
- 206010034972 Photosensitivity reaction Diseases 0.000 description 2
- 229910004298 SiO 2 Inorganic materials 0.000 description 2
- 210000001124 body fluid Anatomy 0.000 description 2
- 230000002596 correlated effect Effects 0.000 description 2
- 230000000875 corresponding effect Effects 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 238000000151 deposition Methods 0.000 description 2
- 230000008021 deposition Effects 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 238000002488 metal-organic chemical vapour deposition Methods 0.000 description 2
- 238000001451 molecular beam epitaxy Methods 0.000 description 2
- 230000036211 photosensitivity Effects 0.000 description 2
- -1 polydimethylsiloxane Polymers 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 230000001235 sensitizing effect Effects 0.000 description 2
- 230000003595 spectral effect Effects 0.000 description 2
- VRBFTYUMFJWSJY-UHFFFAOYSA-N 28804-46-8 Chemical compound ClC1CC(C=C2)=CC=C2C(Cl)CC2=CC=C1C=C2 VRBFTYUMFJWSJY-UHFFFAOYSA-N 0.000 description 1
- 229910000980 Aluminium gallium arsenide Inorganic materials 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 229910002601 GaN Inorganic materials 0.000 description 1
- 229910000530 Gallium indium arsenide Inorganic materials 0.000 description 1
- JMASRVWKEDWRBT-UHFFFAOYSA-N Gallium nitride Chemical compound [Ga]#N JMASRVWKEDWRBT-UHFFFAOYSA-N 0.000 description 1
- 238000012369 In process control Methods 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 238000001069 Raman spectroscopy Methods 0.000 description 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- 229910010413 TiO 2 Inorganic materials 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- KXNLCSXBJCPWGL-UHFFFAOYSA-N [Ga].[As].[In] Chemical compound [Ga].[As].[In] KXNLCSXBJCPWGL-UHFFFAOYSA-N 0.000 description 1
- 238000002835 absorbance Methods 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000003321 amplification Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 238000012512 characterization method Methods 0.000 description 1
- 239000002800 charge carrier Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 239000004205 dimethyl polysiloxane Substances 0.000 description 1
- 238000003618 dip coating Methods 0.000 description 1
- 239000013536 elastomeric material Substances 0.000 description 1
- 238000005566 electron beam evaporation Methods 0.000 description 1
- 238000010894 electron beam technology Methods 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000005284 excitation Effects 0.000 description 1
- 238000000684 flow cytometry Methods 0.000 description 1
- 238000001917 fluorescence detection Methods 0.000 description 1
- 229910052732 germanium Inorganic materials 0.000 description 1
- GNPVGFCGXDBREM-UHFFFAOYSA-N germanium atom Chemical compound [Ge] GNPVGFCGXDBREM-UHFFFAOYSA-N 0.000 description 1
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 description 1
- 238000010965 in-process control Methods 0.000 description 1
- 229910052981 lead sulfide Inorganic materials 0.000 description 1
- 229940056932 lead sulfide Drugs 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 210000002751 lymph Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000011859 microparticle Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000000491 multivariate analysis Methods 0.000 description 1
- 239000002105 nanoparticle Substances 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 230000000737 periodic effect Effects 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 230000010287 polarization Effects 0.000 description 1
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000012088 reference solution Substances 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 238000004544 sputter deposition Methods 0.000 description 1
- ZUHZGEOKBKGPSW-UHFFFAOYSA-N tetraglyme Chemical compound COCCOCCOCCOCCOC ZUHZGEOKBKGPSW-UHFFFAOYSA-N 0.000 description 1
- 238000002207 thermal evaporation Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 230000001052 transient effect Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N21/031—Multipass arrangements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/12—Generating the spectrum; Monochromators
- G01J3/26—Generating the spectrum; Monochromators using multiple reflection, e.g. Fabry-Perot interferometer, variable interference filters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
- G01N21/39—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using tunable lasers
- G01N2021/391—Intracavity sample
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Lasers (AREA)
Abstract
【解決手段】検体22が不在のとき、キャビティ20は、グラフ24における如き強度/エネルギ・ピーク26および28を備えた出力光を提供する。検体22が存在すると、キャビティ20は、検体により影響された出力光であって異なる強度/エネルギ・ピーク30および32を備えた出力光を提供する。各ピークの中心エネルギは、たとえば検体22の屈折率変化によりシフトされる。ピーク32の振幅およびコントラストもまた、たとえば検体22による吸収量変化の故に、ピーク28から減少される。また、増大した吸収量の故に、ピーク32のFWHMもピーク28から増大される。検体により影響された出力光は、たとえば層状透過構造などの構成要素14を介して透過される。
【選択図】図1
Description
感光IC構成要素と、
上記第1および第2強度/エネルギ関数に応じて上記感光IC構成要素上に第1および第2の横方向変化光子エネルギ分布を夫々提供する横方向変化透過構成要素であって、上記第1および第2分布は異なり、該第1および第2分布に応じて上記感光IC構成要素は第1および第2検知結果を夫々提供し、上記第1および第2検知結果は各々、夫々の分布に関する位置、サイズおよび強度の情報の内の少なくともひとつの情報を含み、上記第1および第2検知結果は異なるという横方向変化透過構成要素と
を備えて成ることを特徴とする。
上記キャビティ内に検体が存在するときに、検体により影響された出力光を該キャビティから提供する段階であって、上記検体の存在の結果として、上記検体により影響された出力光は上記第1強度/エネルギ関数とは異なる第2強度/エネルギ関数を有するという段階と、
上記検体により影響された出力光を上記光学キャビティから、横方向変化する光子エネルギ分布を備える光を提供する層状透過構造を介して感光IC上に透過させる段階であって、これに応じて上記感光ICは位置、サイズおよび強度の内の少なくともひとつに依存する検知結果を提供するという段階と
を備えて成ることを特徴とする。
上記レーザ・キャビティ内に検体を存在させて、検体により影響された出力光を上記第1部分的レンジとは異なる光子エネルギの第2部分的レンジ内で上記レーザ・キャビティが提供する様に該レーザ・キャビティを励起する段階と、
上記検体により影響された出力光を上記レーザ・キャビティから、横方向変化する光子エネルギ分布を備える光を提供する層状透過構造を介して感光ICに対して透過させる段階であって、上記第2部分的レンジにおいて上記検体により影響された出力光に応じて上記層状透過構造は上記感光IC上に光スポットを提供し、これに応じて上記感光ICは上記光スポットの位置に依存する検知結果を提供するという段階と、
上記検知結果を使用して上記検体に関する情報を獲得する段階と
を備えて成ることを特徴とする。
この場合には水中のグルコースである検体が在ると、吸収により略々全てのモードの透過が減少し、各モードは、下側のグラフにおける曲線410上のピークに帰着する。曲線410は検体の吸収スペクトルを示することができると共に、円412は個別のサンプリング点である。所望の解像度まで測定するために、キャビティ幅wおよび他のパラメータは十分なサンプリング点を獲得すべく選択されねばならない。
Claims (3)
- 検体を収容することができる少なくとも一個の光学キャビティを含む光学キャビティ構成要素であって、検体が不在のときに上記光学キャビティは第1強度/エネルギ関数を有する出力光を提供し、検体が上記キャビティ内に存在するときに該光学キャビティは検体により影響された出力光を該キャビティから提供し、上記検体により影響された出力光は上記第1強度/エネルギ関数とは異なる第2強度/エネルギ関数を有するという光学キャビティ構成要素と、
感光IC構成要素と、
上記第1および第2強度/エネルギ関数に応じて上記感光IC構成要素上に第1および第2の横方向変化光子エネルギ分布を夫々提供する横方向変化透過構成要素であって、上記第1および第2分布は異なり、該第1および第2分布に応じて上記感光IC構成要素は第1および第2検知結果を夫々提供し、上記第1および第2検知結果は各々、夫々の分布に関する位置、サイズおよび強度の情報の内の少なくともひとつの情報を含み、上記第1および第2検知結果は異なるという横方向変化透過構成要素とを備えて成る、
デバイス。 - 検体を収容することができると共に、検体が不在のときには第1強度/エネルギ関数を以て出力光を提供する光学キャビティを使用する方法であって、
上記キャビティ内に検体が存在するときに、検体により影響された出力光を該キャビティから提供する段階であって、上記検体の存在の結果として、上記検体により影響された出力光は上記第1強度/エネルギ関数とは異なる第2強度/エネルギ関数を有するという段階と、
上記検体により影響された出力光を上記光学キャビティから、横方向変化する光子エネルギ分布を備える光を提供する層状透過構造を介して感光IC上に透過させる段階であって、これに応じて上記感光ICは位置、サイズおよび強度の内の少なくともひとつに依存する検知結果を提供するという段階とを備えて成る、
方法。 - 検体が不在とされて励起されたときに光子エネルギの第1部分的レンジ内で出力光を提供するレーザ・キャビティを使用して検体に関する情報を獲得する方法であって、
上記レーザ・キャビティ内に検体を存在させて、検体により影響された出力光を上記第1部分的レンジとは異なる光子エネルギの第2部分的レンジ内で上記レーザ・キャビティが提供する様に該レーザ・キャビティを励起する段階と、
上記検体により影響された出力光を上記レーザ・キャビティから、横方向変化する光子エネルギ分布を備える光を提供する層状透過構造を介して感光ICに対して透過させる段階であって、上記第2部分的レンジにおいて上記検体により影響された出力光に応じて上記層状透過構造は上記感光IC上に光スポットを提供し、これに応じて上記感光ICは上記光スポットの位置に依存する検知結果を提供するという段階と、
上記検知結果を使用して上記検体に関する情報を獲得する段階とを備えて成る、
方法。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/702,250 | 2007-02-05 | ||
US11/702,250 US7471399B2 (en) | 2007-02-05 | 2007-02-05 | Photosensing optical cavity output light |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2008191147A true JP2008191147A (ja) | 2008-08-21 |
JP5068189B2 JP5068189B2 (ja) | 2012-11-07 |
Family
ID=39397105
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2008017985A Expired - Fee Related JP5068189B2 (ja) | 2007-02-05 | 2008-01-29 | 光学キャビティデバイス及び光学キャビティ出力光を感光する方法 |
Country Status (3)
Country | Link |
---|---|
US (1) | US7471399B2 (ja) |
EP (1) | EP1953529B1 (ja) |
JP (1) | JP5068189B2 (ja) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2008191149A (ja) * | 2007-02-05 | 2008-08-21 | Palo Alto Research Center Inc | 植設用光学キャビティ構造 |
JP2015127703A (ja) * | 2013-12-27 | 2015-07-09 | パロ・アルト・リサーチ・センター・インコーポレーテッドPalo Alto Research Center Incorporated | 波長の中心検出に基づいたセンサ装置および方法 |
KR20180135050A (ko) * | 2016-05-23 | 2018-12-19 | 옥스포드 유니버시티 이노베이션 리미티드 | 개방형 광학 공진기 캐비티에서의 입자 특성화 |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7310153B2 (en) * | 2004-08-23 | 2007-12-18 | Palo Alto Research Center, Incorporated | Using position-sensitive detectors for wavelength determination |
US7522786B2 (en) | 2005-12-22 | 2009-04-21 | Palo Alto Research Center Incorporated | Transmitting light with photon energy information |
US7547904B2 (en) | 2005-12-22 | 2009-06-16 | Palo Alto Research Center Incorporated | Sensing photon energies emanating from channels or moving objects |
US8437582B2 (en) | 2005-12-22 | 2013-05-07 | Palo Alto Research Center Incorporated | Transmitting light with lateral variation |
US7358476B2 (en) * | 2005-12-22 | 2008-04-15 | Palo Alto Research Center Incorporated | Sensing photons from objects in channels |
JPWO2008012926A1 (ja) * | 2006-07-28 | 2009-12-17 | 古河電気工業株式会社 | 光ファイバ |
US7718948B2 (en) * | 2006-12-04 | 2010-05-18 | Palo Alto Research Center Incorporated | Monitoring light pulses |
US9164037B2 (en) | 2007-01-26 | 2015-10-20 | Palo Alto Research Center Incorporated | Method and system for evaluation of signals received from spatially modulated excitation and emission to accurately determine particle positions and distances |
US8821799B2 (en) | 2007-01-26 | 2014-09-02 | Palo Alto Research Center Incorporated | Method and system implementing spatially modulated excitation or emission for particle characterization with enhanced sensitivity |
US7502123B2 (en) * | 2007-02-05 | 2009-03-10 | Palo Alto Research Center Incorporated | Obtaining information from optical cavity output light |
US7936463B2 (en) * | 2007-02-05 | 2011-05-03 | Palo Alto Research Center Incorporated | Containing analyte in optical cavity structures |
US7817276B2 (en) * | 2007-02-05 | 2010-10-19 | Palo Alto Research Center Incorporated | Distinguishing objects |
US7554673B2 (en) | 2007-02-05 | 2009-06-30 | Palo Alto Research Center Incorporated | Obtaining information about analytes using optical cavity output light |
US7817281B2 (en) * | 2007-02-05 | 2010-10-19 | Palo Alto Research Center Incorporated | Tuning optical cavities |
US7545513B2 (en) * | 2007-02-05 | 2009-06-09 | Palo Alto Research Center Incorporated | Encoding optical cavity output light |
US7633629B2 (en) | 2007-02-05 | 2009-12-15 | Palo Alto Research Center Incorporated | Tuning optical cavities |
US7544870B2 (en) * | 2007-02-05 | 2009-06-09 | White Richard H | Music box movement and method of operation thereof |
US9063117B2 (en) * | 2007-02-21 | 2015-06-23 | Paul L. Gourley | Micro-optical cavity with fluidic transport chip for bioparticle analysis |
US8324560B2 (en) * | 2007-03-01 | 2012-12-04 | Koninklijke Philipe Electronics N.V. | Optical detector device |
US8320983B2 (en) * | 2007-12-17 | 2012-11-27 | Palo Alto Research Center Incorporated | Controlling transfer of objects affecting optical characteristics |
US7701580B2 (en) * | 2008-02-01 | 2010-04-20 | Palo Alto Research Center Incorporated | Transmitting/reflecting emanating light with time variation |
US8263955B2 (en) | 2008-12-18 | 2012-09-11 | Palo Alto Research Center Incorporated | Causing relative motion |
US7817254B2 (en) * | 2008-01-30 | 2010-10-19 | Palo Alto Research Center Incorporated | Obtaining information from time variation of sensing results |
US7763856B2 (en) * | 2008-01-31 | 2010-07-27 | Palo Alto Research Center Incorporated | Producing time variation in emanating light |
US8153949B2 (en) * | 2008-12-18 | 2012-04-10 | Palo Alto Research Center Incorporated | Obtaining sensing results indicating time variation |
US8153950B2 (en) * | 2008-12-18 | 2012-04-10 | Palo Alto Research Center Incorporated | Obtaining sensing results and/or data in response to object detection |
US8373860B2 (en) * | 2008-02-01 | 2013-02-12 | Palo Alto Research Center Incorporated | Transmitting/reflecting emanating light with time variation |
US8629981B2 (en) | 2008-02-01 | 2014-01-14 | Palo Alto Research Center Incorporated | Analyzers with time variation based on color-coded spatial modulation |
US7961326B2 (en) * | 2008-08-21 | 2011-06-14 | Palo Alto Research Center Incorporated | Method of detecting the concentration of an analyte |
US9161714B2 (en) * | 2008-08-21 | 2015-10-20 | Palo Alto Research Center Incorporated | Specificity of analyte detection in etalons |
US20110207207A1 (en) * | 2008-10-28 | 2011-08-25 | Gibson Emily A | Microfluidic cell sorter utilizing broadband coherent anti-stokes raman scattering |
DE102009021936A1 (de) * | 2009-05-19 | 2010-11-25 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Optisches Filter und ein Verfahren zur Herstellung eines optischen Filters |
US9664563B2 (en) * | 2009-12-02 | 2017-05-30 | University Of Hawaii | Fabry-perot fourier transform spectrometer |
AU2015261653B2 (en) * | 2009-12-02 | 2017-05-25 | University Of Hawaii | Fabry-Perot Fourier transform spectrometer |
US9029800B2 (en) | 2011-08-09 | 2015-05-12 | Palo Alto Research Center Incorporated | Compact analyzer with spatial modulation and multiple intensity modulated excitation sources |
US8723140B2 (en) | 2011-08-09 | 2014-05-13 | Palo Alto Research Center Incorporated | Particle analyzer with spatial modulation and long lifetime bioprobes |
US9952033B2 (en) | 2014-02-14 | 2018-04-24 | Palo Alto Research Center Incorporated | Spatial modulation of light to determine object length |
US10451482B2 (en) | 2014-02-14 | 2019-10-22 | Palo Alto Research Center Incorporated | Determination of color characteristics of objects using spatially modulated light |
US9528925B2 (en) * | 2014-02-14 | 2016-12-27 | Palo Alto Research Center Incorporated | Spatial modulation of light to determine object position |
DE102014104595A1 (de) * | 2014-04-01 | 2015-10-01 | Michael Himmelhaus | Verfahren und Vorrichtung zur labelfreien Detektion eines Analyten |
US9400174B2 (en) | 2014-04-07 | 2016-07-26 | Palo Alto Research Center Incorporated | Monitor for particle injector |
JP2016161802A (ja) * | 2015-03-03 | 2016-09-05 | 富士通株式会社 | 可変光減衰器及び光モジュール |
US20170159430A1 (en) * | 2015-12-03 | 2017-06-08 | Schlumberger Technology Corporation | Wellbore fluid analysis |
RU2016112801A (ru) * | 2016-04-04 | 2017-10-09 | Евгений Михайлович Силкин | Способ контроля качества наполнения газом колбы светодиодной лампы |
FR3081997B1 (fr) * | 2018-05-31 | 2021-04-16 | Commissariat Energie Atomique | Dispositif et procede d'observation de particules, en particulier des particules submicroniques |
US11016314B2 (en) * | 2018-08-14 | 2021-05-25 | International Business Machines Corporation | Non-volatilely programmable optical devices and methods to configure such optical devices |
EP3825678A1 (en) * | 2019-11-22 | 2021-05-26 | Ams Ag | Apparatus and method for detecting objects |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2003131015A (ja) * | 2001-10-23 | 2003-05-08 | Nireco Corp | コリメータ及び分光測光装置 |
JP2005326393A (ja) * | 2004-04-12 | 2005-11-24 | Nireco Corp | 分光透過率測定装置、透過型厚さ計、色彩値測定装置、分光透過率測定方法、厚さ測定方法、及び色彩値測定方法 |
JP2005351754A (ja) * | 2004-06-10 | 2005-12-22 | Canon Inc | センサ及びセンサの製造方法 |
JP2006133013A (ja) * | 2004-11-04 | 2006-05-25 | Nippon Telegr & Teleph Corp <Ntt> | 半導体レーザ吸収分光装置 |
Family Cites Families (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5144498A (en) * | 1990-02-14 | 1992-09-01 | Hewlett-Packard Company | Variable wavelength light filter and sensor system |
US5166755A (en) * | 1990-05-23 | 1992-11-24 | Nahum Gat | Spectrometer apparatus |
US5784507A (en) * | 1991-04-05 | 1998-07-21 | Holm-Kennedy; James W. | Integrated optical wavelength discrimination devices and methods for fabricating same |
JPH05240774A (ja) * | 1992-03-02 | 1993-09-17 | Hitachi Ltd | 光学セル及び光学検出装置とこれを用いる試料分離検出装置 |
WO1995020144A1 (en) | 1994-01-20 | 1995-07-27 | British Telecommunications Public Limited Company | Optical wavelength sensor |
US5793485A (en) | 1995-03-20 | 1998-08-11 | Sandia Corporation | Resonant-cavity apparatus for cytometry or particle analysis |
US5677769A (en) | 1995-05-30 | 1997-10-14 | Imra America | Optical sensor utilizing rare-earth-doped integrated-optic lasers |
JP2000515778A (ja) * | 1996-07-08 | 2000-11-28 | アニマス コーポレーシヨン | 体液成分レベルの生体内測定および制御のための埋込可能センサーおよびシステム |
US6908770B1 (en) * | 1998-07-16 | 2005-06-21 | Board Of Regents, The University Of Texas System | Fluid based analysis of multiple analytes by a sensor array |
US6187592B1 (en) * | 1998-12-23 | 2001-02-13 | Sandia Corporation | Method for determining properties of red blood cells |
CA2271159A1 (en) * | 1999-04-30 | 2000-10-30 | Jds Fitel Inc. | Optical hybrid device |
US6295130B1 (en) * | 1999-12-22 | 2001-09-25 | Xerox Corporation | Structure and method for a microelectromechanically tunable fabry-perot cavity spectrophotometer |
SE517341C2 (sv) * | 2000-01-10 | 2002-05-28 | Ericsson Telefon Ab L M | Integrerad våglängdsmonitor för laserljus |
US6580507B2 (en) * | 2000-03-02 | 2003-06-17 | Sd Acquisition Inc. | Single source, single detector chip, multiple-longitudinal channel electromagnetic radiation absorbance and fluorescence monitoring system |
US6785002B2 (en) * | 2001-03-16 | 2004-08-31 | Optical Coating Laboratory, Inc. | Variable filter-based optical spectrometer |
US6952603B2 (en) * | 2001-03-16 | 2005-10-04 | Roche Diagnostics Operations, Inc. | Subcutaneous analyte sensor |
US20030161024A1 (en) * | 2002-02-27 | 2003-08-28 | Qin Zhang | Dual fibers coupled to an etalon |
US6768555B2 (en) * | 2002-03-21 | 2004-07-27 | Industrial Technology Research Institute | Fabry-Perot filter apparatus with enhanced optical discrimination |
US6700664B1 (en) * | 2002-08-15 | 2004-03-02 | Jds Uniphase Corporation | Optical channel monitoring device |
WO2004083820A2 (en) * | 2003-03-19 | 2004-09-30 | Trustees Of Boston University | Resonant cavity biosensor |
US7064836B2 (en) * | 2003-04-21 | 2006-06-20 | The Board Of Trustees Of The Leland Stanford Junior University | Brewster's angle flow cell for cavity ring-down spectroscopy |
US7065112B2 (en) * | 2003-05-12 | 2006-06-20 | Princeton Optronics, Inc. | Wavelength locker |
US7310153B2 (en) * | 2004-08-23 | 2007-12-18 | Palo Alto Research Center, Incorporated | Using position-sensitive detectors for wavelength determination |
US7387892B2 (en) * | 2004-09-01 | 2008-06-17 | Palo Alto Research Center Incorporated | Biosensor using microdisk laser |
US7259856B2 (en) * | 2005-02-16 | 2007-08-21 | Picarro, Inc. | Method for the precise measurement of the wavelength of light |
US7466409B2 (en) * | 2005-06-08 | 2008-12-16 | California Institute Of Technology | Method and apparatus for CMOS imagers and spectroscopy |
US7433552B2 (en) * | 2005-12-22 | 2008-10-07 | Palo Alto Research Center Incorporated | Obtaining analyte information |
US7315667B2 (en) * | 2005-12-22 | 2008-01-01 | Palo Alto Research Center Incorporated | Propagating light to be sensed |
US7545513B2 (en) | 2007-02-05 | 2009-06-09 | Palo Alto Research Center Incorporated | Encoding optical cavity output light |
US7936463B2 (en) | 2007-02-05 | 2011-05-03 | Palo Alto Research Center Incorporated | Containing analyte in optical cavity structures |
US7554673B2 (en) | 2007-02-05 | 2009-06-30 | Palo Alto Research Center Incorporated | Obtaining information about analytes using optical cavity output light |
US7633629B2 (en) | 2007-02-05 | 2009-12-15 | Palo Alto Research Center Incorporated | Tuning optical cavities |
US7817281B2 (en) | 2007-02-05 | 2010-10-19 | Palo Alto Research Center Incorporated | Tuning optical cavities |
US7852490B2 (en) | 2007-02-05 | 2010-12-14 | Palo Alto Research Center Incorporated | Implanting optical cavity structures |
US7817276B2 (en) | 2007-02-05 | 2010-10-19 | Palo Alto Research Center Incorporated | Distinguishing objects |
US7502123B2 (en) | 2007-02-05 | 2009-03-10 | Palo Alto Research Center Incorporated | Obtaining information from optical cavity output light |
-
2007
- 2007-02-05 US US11/702,250 patent/US7471399B2/en active Active
-
2008
- 2008-01-29 JP JP2008017985A patent/JP5068189B2/ja not_active Expired - Fee Related
- 2008-02-01 EP EP08150966.3A patent/EP1953529B1/en active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2003131015A (ja) * | 2001-10-23 | 2003-05-08 | Nireco Corp | コリメータ及び分光測光装置 |
JP2005326393A (ja) * | 2004-04-12 | 2005-11-24 | Nireco Corp | 分光透過率測定装置、透過型厚さ計、色彩値測定装置、分光透過率測定方法、厚さ測定方法、及び色彩値測定方法 |
JP2005351754A (ja) * | 2004-06-10 | 2005-12-22 | Canon Inc | センサ及びセンサの製造方法 |
JP2006133013A (ja) * | 2004-11-04 | 2006-05-25 | Nippon Telegr & Teleph Corp <Ntt> | 半導体レーザ吸収分光装置 |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2008191149A (ja) * | 2007-02-05 | 2008-08-21 | Palo Alto Research Center Inc | 植設用光学キャビティ構造 |
JP2015127703A (ja) * | 2013-12-27 | 2015-07-09 | パロ・アルト・リサーチ・センター・インコーポレーテッドPalo Alto Research Center Incorporated | 波長の中心検出に基づいたセンサ装置および方法 |
KR20180135050A (ko) * | 2016-05-23 | 2018-12-19 | 옥스포드 유니버시티 이노베이션 리미티드 | 개방형 광학 공진기 캐비티에서의 입자 특성화 |
US10948397B2 (en) | 2016-05-23 | 2021-03-16 | Oxford University Innovation Limited | Particle characterisation in open optical resonator cavity |
KR102237233B1 (ko) | 2016-05-23 | 2021-04-06 | 옥스포드 유니버시티 이노베이션 리미티드 | 개방형 광학 공진기 캐비티에서의 입자 특성화 |
Also Published As
Publication number | Publication date |
---|---|
EP1953529B1 (en) | 2013-11-20 |
EP1953529A1 (en) | 2008-08-06 |
JP5068189B2 (ja) | 2012-11-07 |
US7471399B2 (en) | 2008-12-30 |
US20080186503A1 (en) | 2008-08-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP5068189B2 (ja) | 光学キャビティデバイス及び光学キャビティ出力光を感光する方法 | |
JP5160253B2 (ja) | 光学キャビティ出力光から情報を獲得する方法 | |
JP5242183B2 (ja) | 移動する検体の光検出方法及びシステム | |
JP5361198B2 (ja) | 光学キャビティ出力光をコード化する方法 | |
JP5672422B2 (ja) | 物体の識別 | |
JP5816404B2 (ja) | 光学キャビティ構造における検体の検知デバイス及び方法 | |
US7358476B2 (en) | Sensing photons from objects in channels | |
US7547904B2 (en) | Sensing photon energies emanating from channels or moving objects | |
US7291824B2 (en) | Photosensing throughout energy range and in subranges | |
US7386199B2 (en) | Providing light to channels or portions |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20110120 |
|
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20120627 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20120717 |
|
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20120814 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20150824 Year of fee payment: 3 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 5068189 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
LAPS | Cancellation because of no payment of annual fees |