JP2008007470A - Method for masking iron smell and taste - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a method for masking the iron smell and taste of a liquid composition, and to provide an iron-containing liquid composition whose iron smell and taste are masked. <P>SOLUTION: The method for masking the iron smell and taste of the present invention comprises adding a thickening polysaccharide to a liquid composition having the iron smell and taste. Thereby, the iron smell and taste can be controlled, and the method is very useful. The present invention liquid composition produced thus reduces the unpleasant taste and smell originated from iron, can easily be drunk, does not leave an unpleasant aftertaste, and is useful as an iron-containing composition, especially a composition for preventing/treating anemia and the like. <P>COPYRIGHT: (C)2008,JPO&INPIT

Description

  The present invention relates to a novel masking method for an iron odor possessed by a liquid composition and an iron-containing liquid composition in which the iron odor is masked.

  Iron is one of the essential micronutrients essential for maintaining life, and is mainly distributed in hemoglobin of red blood cells in blood, ferritin in liver, myoglobin in muscle tissue, and oxygen in body tissues. It is involved in important functions such as transportation and intracellular energy production. Therefore, it is known that an insufficiency of iron in the body may cause symptoms such as anemia, gastrointestinal disorders, reduced thinking ability, and irritability. According to the 2004 National Nutrition Survey, Japanese intake of iron The amount tends to be deficient and it is very important to meet the daily nutritional requirements of iron.

  Therefore, the development of liquid pharmaceuticals and nutritional supplements with enhanced iron content has been promoted. In particular, internal liquids are widely used because they are easy to take, but in the case of iron, it is suitable for oral replenishment with an aqueous solution because of its unique taste and odor (iron odor). In order to solve this problem, various attempts have been made to mask the iron odor.

  For example, water-soluble dietary fiber (see Patent Document 1), eugenol and / or L-type amino acid salt and gluconate (see Patent Document 2), non-reducing sugar and / or high-intensity sweetener (see Patent Document 3) ), Ground yellow and xylitol (see Patent Literature 4), Toki (see Patent Literature 5), glucose (see Patent Literature 6), sucrose (see Patent Literature 7), non-reducing substance (see Patent Literature 8), trehalose (See Patent Document 9), sucralose (see Patent Document 10), at least one acidulant selected from acetic acid, gluconic acid and lactic acid (see Patent Document 11), indigestible dextrin (see Patent Document 12), nonionic Surfactant (see Patent Document 13), mucopolysaccharide (see Patent Document 14), collagen, meat storage, fish, corn, or wheat-derived peptide (see Patent Document 15), fermentation And / or yeast extract (see Patent Document 16), 綵 c1-aminobutyric acid (see Patent Document 17), cyclofructan (see Patent Document 18), and inositol (see Patent Document 19), each of which contains iron. It is disclosed that a masking effect of iron odor can be obtained by adding to the above. However, it has not been reported so far that the thickener functions as an iron odor masking agent in a liquid composition such as an internal liquid solution having an iron odor. Patent Document 1 describes an iron taste-reducing health food and drink obtained by mixing and drying a water-soluble color group fiber such as pectin and an iron compound in an aqueous solution containing an organic solvent. It does not provide an iron odor masking method.

JP 05-123136 A JP-A-10-101570 JP 11-178543 A JP 2000-169385 A JP 2000-226327 A JP 2000-239153 A JP 2000-239154 A JP 2000-239155 A JP 2000-239156 A JP 2000-239173 A JP 2000-279143 A JP 2001-316246 A JP 2002-080347 A JP 2002-161040 A JP 2004-315439 A JP 2004-315440 A JP 2004-315441 A JP 2004-337133 A JP 2005-255653 A

  The objective of this invention is providing the iron-containing liquid composition by which the iron flavor masking method and the iron flavor masking of the liquid composition characterized by adding thickening polysaccharide.

  As a result of intensive studies on the method for masking the iron odor in a liquid composition, the present inventors have studied the liquid composition by adding a thickening polysaccharide at a low concentration to a liquid composition having an iron odor. The present inventors have found that the iron odor of a product can be masked and have completed the present invention.

  The iron odor masking method of the present invention is a simple method of adding a small amount of thickening polysaccharide to a liquid composition having an iron odor. It is very useful because it can be left behind. Conventionally known iron odor masking agents have a unique and unpleasant taste, and in particular in the case of pharmaceuticals, etc. Although there is a limitation, the iron flavor masking method by adding a thickening polysaccharide in the present invention is effective with a small amount of addition, so there is no problem in that respect and it is very practical. Is. The iron taste masking method of the present invention reduces the unpleasant taste and odor derived from iron, makes it possible to provide an iron-containing liquid composition that is easy to drink and does not leave an unpleasant aftertaste. Available.

The present invention relates to an iron flavor masking method for a liquid composition characterized by adding a thickening polysaccharide, and further relates to an iron-containing liquid composition in which the iron flavor is suppressed by the masking method.
The thickening polysaccharide used in the odor masking agent of the present invention is a water-soluble polysaccharide having the property of showing viscosity or gelling when dissolved in water, and is generally used in foods or pharmaceuticals. Things can be used. Examples include pectin, xanthan gum, locust bean gum, guar gum, tamarind gum, carrageenan and the like, and these can be used alone or in combination of two or more. The addition ratio of the thickening polysaccharide can be appropriately determined according to the liquid composition having an iron odor to be added, but in the present invention, the effect of reducing the target iron odor can be achieved even at a low concentration. Since it is obtained, in order to obtain a liquid composition having almost no viscosity like a normal drink, it can be added in an amount of 0.01 to 1% (w / v) to the liquid composition, An addition amount of 0.025 to 0.5% (w / v) is particularly preferable.

  The iron compound used in the iron-containing liquid composition of the present invention includes, for example, ammonium iron citrate, ferric pyrophosphate, sodium ferrous citrate, iron citrate, iron lactate, ferrous gluconate, sugar-containing Water-soluble iron compounds such as iron oxide, ferric chloride, ferrous sulfate, etc. can be mentioned, and examples of pharmaceuticals with precedent use of internal use include ammonium ammonium citrate, ferric pyrophosphate, sodium ferrous citrate , Iron citrate, iron lactate, ferrous gluconate and ferrous sulfate are preferable, and particularly, ammonium iron citrate and ferric pyrophosphate which are actually used in drinks and the like are suitable for the present invention. is there. The compounding amount is not particularly limited, but considering the nutrient intake, for example, in terms of the iron content in the iron compound, for example, 0.5 to 20 mg of iron (50. To 0.04% (w / v)).

  In addition, vitamins, minerals, amino acids and salts thereof, anhydrous caffeine, and the like can be blended as other components in the liquid composition such as the internal liquid preparation of the present invention as long as the effects of the present invention are not impaired. Furthermore, the internal use liquid preparation of the present invention usually contains various additives used as additives for internal use liquid preparations, such as sweeteners, flavoring agents, stabilizers, pH regulators, preservatives, solubilizers, and fragrances. Can be appropriately added depending on the purpose.

  EXAMPLES Next, the present invention will be specifically described with reference to examples, but the present invention is not limited thereto.

  A sensory test was conducted with 13 randomly selected men and women as panelists. According to the manufacturing method of general-purpose internal use liquid preparation, riboflavin (vitamin B2) sodium phosphate 3 mg, pyridoxine (vitamin B6) hydrochloride 25 mg, nicotinamide 30 mg, anhydrous caffeine 50 mg, calcium gluconate 1000 mg, ammonium iron citrate 20 mg ( 3 mg) as iron, 100 mg L-aspartate potassium, 100 mg magnesium L-aspartate, 800 mg taurine (aminoethylsulfonic acid), liquid sugar, citric acid, DL-malic acid, caramel, sodium benzoate, To 50 mL of an aqueous solution prepared by appropriately adding butyl paraoxybenzoate, ethanol, and fragrance, pectin or xanthan gum, which is a thickening polysaccharide, is added so as to have a concentration of 0.1% (w / v). A test solution was prepared. In addition, the aqueous solution which produced similarly and did not add thickening polysaccharide was used as a control | contrast liquid.

  When the panelists took these two test solutions and the control solution and evaluated the iron odor, 10 out of 13 people in both test solutions evaluated that the iron odor was suppressed compared to the control solution. did. The remaining three were evaluated as having no particular change. In addition, as a result of preparing and tasting an aqueous solution having the same composition as above with pectin or xanthan gum added so as to have a concentration of 0.05% (w / v), the iron odor is similarly suppressed. Was obtained.

  The iron odor masking method of the present invention is very useful because it can suppress the iron odor by adding a thickening polysaccharide to a liquid composition having an iron odor. The liquid composition of the present invention thus produced is reduced in iron-derived unpleasant taste and odor, is easy to drink, and does not leave an unpleasant aftertaste. -Useful as a therapeutic composition.

Claims (13)

A method for masking an iron flavor, comprising adding a thickening polysaccharide to a liquid composition having an iron flavor. The method for masking an iron flavor according to claim 1, wherein the thickening polysaccharide is added to the liquid composition at a concentration of 0.01 to 1% (w / v). The method for masking an iron flavor according to claim 2, wherein the thickening polysaccharide is added to the liquid composition at a concentration of 0.025 to 0.5% (w / v). The thickening polysaccharide is one or two or more selected from the group consisting of pectin, xanthan gum, locust bean gum, guar gum, tamarind gum and carrageenan. Masking method. The method for masking an iron flavor according to any one of claims 1 to 4, wherein the liquid composition having an iron flavor contains 0.001 to 0.4% (w / v) of iron as iron. The iron content consists of ammonium iron citrate, ferric pyrophosphate, sodium ferrous citrate, iron citrate, iron lactate, ferrous gluconate, ferrous sugar oxide, ferric chloride and ferrous sulfate 6. The method for masking iron flavor according to claim 5, wherein the masking method is one or more selected from the group. A liquid composition comprising a thickening polysaccharide for masking an iron odor. 8. The liquid composition according to claim 7, comprising a thickening polysaccharide at a concentration of 0.01 to 1% (w / v). The liquid composition according to claim 8, comprising the thickening polysaccharide at a concentration of 0.025 to 0.5% (w / v). The liquid composition according to any one of claims 7 to 9, wherein the thickening polysaccharide is one or more selected from the group consisting of pectin, xanthan gum, locust bean gum, guar gum, tamarind gum and carrageenan. The liquid composition according to any one of claims 7 to 10, comprising 0.001 to 0.4% (w / v) of iron as iron. The iron content consists of ammonium iron citrate, ferric pyrophosphate, sodium ferrous citrate, iron citrate, iron lactate, ferrous gluconate, ferrous sugar oxide, ferric chloride and ferrous sulfate The liquid composition according to claim 11, wherein the liquid composition is one or more selected from the group. The liquid composition according to any one of claims 7 to 12, which is used for the prevention or treatment of anemia.