JP2007529549A - 神経エネルギーバランスを変化させることによる摂食行動の制御 - Google Patents

神経エネルギーバランスを変化させることによる摂食行動の制御 Download PDF

Info

Publication number
JP2007529549A
JP2007529549A JP2007504139A JP2007504139A JP2007529549A JP 2007529549 A JP2007529549 A JP 2007529549A JP 2007504139 A JP2007504139 A JP 2007504139A JP 2007504139 A JP2007504139 A JP 2007504139A JP 2007529549 A JP2007529549 A JP 2007529549A
Authority
JP
Japan
Prior art keywords
ampk
subject
compound
food intake
hypothalamic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2007504139A
Other languages
English (en)
Japanese (ja)
Other versions
JP2007529549A5 (enExample
Inventor
ガブリエル・ブイ・ロネット
フランシス・ピー・クハジュダ
ジャガン・エヌ・トゥパリ
レスリー・イー・ランドリー
ティモシー・エイチ・モラン
ユン−キョン・キム
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fasgen LLC
Original Assignee
Fasgen LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fasgen LLC filed Critical Fasgen LLC
Publication of JP2007529549A publication Critical patent/JP2007529549A/ja
Publication of JP2007529549A5 publication Critical patent/JP2007529549A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2007504139A 2004-03-18 2005-03-18 神経エネルギーバランスを変化させることによる摂食行動の制御 Pending JP2007529549A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55422804P 2004-03-18 2004-03-18
PCT/US2005/009069 WO2005089773A1 (en) 2004-03-18 2005-03-18 Control of feeding behavior by changing neuronal energy balance

Publications (2)

Publication Number Publication Date
JP2007529549A true JP2007529549A (ja) 2007-10-25
JP2007529549A5 JP2007529549A5 (enExample) 2008-05-08

Family

ID=34993435

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007504139A Pending JP2007529549A (ja) 2004-03-18 2005-03-18 神経エネルギーバランスを変化させることによる摂食行動の制御

Country Status (6)

Country Link
US (1) US20080119548A1 (enExample)
EP (1) EP1732572A4 (enExample)
JP (1) JP2007529549A (enExample)
AU (1) AU2005222707B2 (enExample)
CA (1) CA2560035A1 (enExample)
WO (1) WO2005089773A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015015818A1 (ja) * 2013-07-31 2015-02-05 大学共同利用機関法人自然科学研究機構 糖尿病による代謝異常を改善するための組成物

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20100016016A (ko) * 2007-03-30 2010-02-12 산토리 홀딩스 가부시키가이샤 교감 신경 활동 항진 작용을 갖는 의약 조성물 또는 음식물
BR112024002354A2 (pt) * 2021-08-06 2024-04-30 Centre Nat Rech Scient Populações de pequenas vesículas extracelulares para uso no tratamento de obesidade
EP4137148A1 (en) * 2021-08-17 2023-02-22 Universidade de Santiago de Compostela Small extracellular vesicles expressing a dominant negative ampk alpha 1 mutant for use in the treatment of obesity

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5981575A (en) * 1996-11-15 1999-11-09 Johns Hopkins University, The Inhibition of fatty acid synthase as a means to reduce adipocyte mass
WO2001010449A1 (en) * 1999-08-09 2001-02-15 Trustees Of Boston University Method of maintaining vascular integrity using aicar (5-amino-4-imidazole riboside) and related compounds
KR20030016228A (ko) * 2000-02-16 2003-02-26 존스 홉킨스 유니버시티 스쿨 오브 메디슨 신경펩티드 y 농도의 감소에 의해 유도되는 체중 감량
WO2001093873A1 (en) * 2000-06-06 2001-12-13 Trustees Of Boston University Use of aicar and related compounds
WO2002009726A1 (en) * 2000-07-31 2002-02-07 Trustees Of Boston University Methods of treating conditions associated with insulin resistance with aicar, (5-amino-4-imidazole carboxamide riboside) and related compounds
US20030212013A1 (en) * 2001-06-14 2003-11-13 Winder William W Use of amp kinase activators for treatment type 2 diabetes and insulin resistance
US20050143467A1 (en) * 2002-02-08 2005-06-30 The Johns Hopkins University School Of Medicine Licensing And Technology Development Stimulation of cpt-1 as a means to reduce weight

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JPN6011000137, The Journal of Clinical Investigation, 2001, Vol.108,No.8, p.1167−1174 *
JPN6011000143, Andersson U, et al., "AMP−activated Protein Kinase Plays a Role in the Control of Food Intake", JBC Papers in Press, 20040123 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015015818A1 (ja) * 2013-07-31 2015-02-05 大学共同利用機関法人自然科学研究機構 糖尿病による代謝異常を改善するための組成物

Also Published As

Publication number Publication date
AU2005222707B2 (en) 2010-06-17
US20080119548A1 (en) 2008-05-22
AU2005222707A1 (en) 2005-09-29
CA2560035A1 (en) 2005-09-29
EP1732572A4 (en) 2007-04-18
EP1732572A1 (en) 2006-12-20
WO2005089773A1 (en) 2005-09-29

Similar Documents

Publication Publication Date Title
Buler et al. SIRT5 is under the control of PGC‐1α and AMPK and is involved in regulation of mitochondrial energy metabolism
Landree et al. C75, a fatty acid synthase inhibitor, modulates AMP-activated protein kinase to alter neuronal energy metabolism
Egawa et al. Caffeine acutely activates 5′ adenosine monophosphate–activated protein kinase and increases insulin-independent glucose transport in rat skeletal muscles
US10526418B2 (en) Modulators of ACYL-COA lysocardiolipin acyltransferase 1 (ALCAT1) and uses thereof
US20020028779A1 (en) Methods for treating neuropathological states and neurogenic inflammatory states and methods for identifying compounds useful therein
US20110287026A1 (en) Sirt4 and uses thereof
US20120134985A1 (en) Methods for modulating metabolic and circadian rhythms
Oguri et al. Tetrahydrobiopterin activates brown adipose tissue and regulates systemic energy metabolism
Park et al. Extracellular vimentin alters energy metabolism and induces adipocyte hypertrophy
Kim et al. The glutamate agonist homocysteine sulfinic acid stimulates glucose uptake through the calcium-dependent AMPK-p38 MAPK-protein kinase C ζ pathway in skeletal muscle cells
JP2007529549A (ja) 神経エネルギーバランスを変化させることによる摂食行動の制御
Li et al. d-Glucosamine induces circadian phase delay by promoting BMAL1 degradation through AMPK/mTOR pathway
Forget et al. Impact of basic FGF expression in astrocytes on dopamine neuron synaptic function and development
Rohrbach et al. Disconnection between the early onset anorectic effects by C75 and hypothalamic fatty acid synthase inhibition in rodents
Salgado et al. GKRP-dependent modulation of feeding behavior by tanycyte-released monocarboxylates
Suzuki et al. Na+, K+-ATPase activity is inhibited in cultured intestinal epithelial cells by endotoxin or nitric oxide
US20130039857A1 (en) Methods of suppressing cancer, increasing weight loss and/or increasing insulin sensitivity
US20070015720A1 (en) Modulation of endogenous AICAR levels for the treatment of diabetes and obesity
Murata Regulation of glucose transporter Glut4 by insulin
Jaleh Role of GLUD1 in determining the anabolic response to amino acids in skeletal muscle
Kumari Molecular Mechanisms of Metabolic Reprogramming in Pancreatic Cancer
JP2008247765A (ja) Nfat2発現抑制剤および破骨細胞形成抑制剤
JP2006514828A (ja) スフィンゴシンキナーゼの機能的レベルを調節することによって上皮細胞活性を調節する方法
Buler et al. SIRT5 is under the control of PGC-1 and AMPK and is involved in regulation of mitochondrial energy metabolism
CA2434696A1 (en) P27 prevents cellular migration

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20080317

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20080317

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20110118

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20111025