JP2007516701A5 - - Google Patents
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- Publication number
- JP2007516701A5 JP2007516701A5 JP2006538829A JP2006538829A JP2007516701A5 JP 2007516701 A5 JP2007516701 A5 JP 2007516701A5 JP 2006538829 A JP2006538829 A JP 2006538829A JP 2006538829 A JP2006538829 A JP 2006538829A JP 2007516701 A5 JP2007516701 A5 JP 2007516701A5
- Authority
- JP
- Japan
- Prior art keywords
- saa
- fpr
- hiv
- wkymwvm
- peprotec
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Description
ＦＰＲおよびＦＰＲＬ１のアゴニスト、可溶性のＡ−ＳＡＡ、ＷＫＹＭＷＶｍペプチド、細菌走化性ペプチドｆＭＬＦ、および可能なその約８．６ｋＤａのフラグメントは、Ａ−ＳＡＡを用いた特異的ウェスタンブロット法での我々の実験に示されるようにリン酸化（図８）およびＦＰＲ活性化によるＨＩＶ−１コレセプターＣＣＲ５およびＣＸＣＲ４の両方のダウン修飾（３４−３７）を誘導する。それで、報告されるように（３１、３７、３８）、Ａ−ＳＡＡタンパク質がＨＩＶ−１感染を阻害したことが示された（図９）。Peprotec（登録商標）から購入された、これらのアッセイに用いられたＡ−ＳＡＡは、約８．６ｋＤａのフラグメントを示す（図１０）。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51710403P | 2003-11-05 | 2003-11-05 | |
| US58072004P | 2004-06-21 | 2004-06-21 | |
| PCT/EP2004/013393 WO2005044292A2 (en) | 2003-11-05 | 2004-11-05 | Biomarkers of resistance to hiv-infections in humans and biological applications thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007516701A JP2007516701A (ja) | 2007-06-28 |
| JP2007516701A5 true JP2007516701A5 (ja) | 2008-01-17 |
Family
ID=34576787
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006538829A Pending JP2007516701A (ja) | 2003-11-05 | 2004-11-05 | ヒトのｈｉｖ感染に対して抵抗性のバイオマーカーおよびその生物学的適用 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20070009926A1 (ja) |
| EP (1) | EP1748789B1 (ja) |
| JP (1) | JP2007516701A (ja) |
| AT (1) | ATE493142T1 (ja) |
| AU (1) | AU2004287205A1 (ja) |
| BR (1) | BRPI0416240A (ja) |
| CA (1) | CA2544972C (ja) |
| CY (1) | CY1113088T1 (ja) |
| DE (1) | DE602004030830D1 (ja) |
| DK (1) | DK1748789T3 (ja) |
| PL (1) | PL1748789T3 (ja) |
| PT (1) | PT1748789E (ja) |
| WO (1) | WO2005044292A2 (ja) |
| ZA (1) | ZA200604550B (ja) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101361968B (zh) | 2007-08-06 | 2011-08-03 | 健能隆医药技术（上海）有限公司 | 白介素-22在治疗脂肪肝中的应用 |
| US10545149B2 (en) * | 2008-10-06 | 2020-01-28 | Morehouse School Of Medicine | Detection of HIV-related proteins in urine |
| GB201002409D0 (en) * | 2010-02-12 | 2010-03-31 | Univ Nottingham | Methods |
| BR112013008697A2 (pt) | 2010-09-24 | 2016-06-21 | Massachusetts Inst Technology | géis nanoestruturados capazes de liberação controlada de agentes encapsulados |
| JP6456356B2 (ja) | 2013-03-15 | 2019-01-23 | ジェネンテック， インコーポレイテッド | ＩＬ−２２ポリペプチド及びＩＬ−２２Ｆｃ融合タンパク質並びに使用方法 |
| EP3054978B1 (en) | 2013-10-08 | 2019-03-06 | Georgia State University Research Foundation, Inc. | Compositions including il-18 and il-22 and their use in anti-viral therapies |
| CN104623637A (zh) | 2013-11-07 | 2015-05-20 | 健能隆医药技术（上海）有限公司 | Il-22二聚体在制备静脉注射药物中的应用 |
| WO2017181143A1 (en) | 2016-04-15 | 2017-10-19 | Generon (Shanghai) Corporation, Ltd. | Use of il-22 in treating necrotizing enterocolitis |
| US11839605B2 (en) * | 2018-10-11 | 2023-12-12 | Alivio Therapeutics, Inc. | Non-injectable hydrogel formulations for smart release |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU4208799A (en) * | 1998-05-29 | 1999-12-13 | Human Genome Sciences, Inc. | Interleukins-21 and 22 |
| US20010023070A1 (en) * | 1998-05-29 | 2001-09-20 | Reinhard Ebner | Interleukins-21 and 22 |
| US6939545B2 (en) * | 1999-04-28 | 2005-09-06 | Genetics Institute, Llc | Composition and method for treating inflammatory disorders |
| US20030170823A1 (en) * | 1999-12-23 | 2003-09-11 | Presnell Scott R. | Novel cytokine ZCYTO18 |
| GB0024442D0 (en) * | 2000-10-05 | 2000-11-22 | Isis Innovation | Genetic factors affecting the outcome of viral infections |
| AU2002240137A1 (en) * | 2001-01-30 | 2002-08-12 | University Of Iowa Research Foundation | Antiviral activities of primate theta defensins and mammalian cathelicidins |
-
2004
- 2004-11-05 AT AT04803279T patent/ATE493142T1/de active
- 2004-11-05 EP EP04803279A patent/EP1748789B1/en not_active Not-in-force
- 2004-11-05 CA CA2544972A patent/CA2544972C/en not_active Expired - Fee Related
- 2004-11-05 BR BRPI0416240-4A patent/BRPI0416240A/pt not_active Application Discontinuation
- 2004-11-05 DK DK04803279.1T patent/DK1748789T3/da active
- 2004-11-05 PT PT04803279T patent/PT1748789E/pt unknown
- 2004-11-05 JP JP2006538829A patent/JP2007516701A/ja active Pending
- 2004-11-05 WO PCT/EP2004/013393 patent/WO2005044292A2/en active Application Filing
- 2004-11-05 PL PL04803279T patent/PL1748789T3/pl unknown
- 2004-11-05 DE DE602004030830T patent/DE602004030830D1/de active Active
- 2004-11-05 AU AU2004287205A patent/AU2004287205A1/en not_active Abandoned
-
2006
- 2006-05-05 US US11/381,811 patent/US20070009926A1/en not_active Abandoned
- 2006-06-02 ZA ZA2006/04550A patent/ZA200604550B/en unknown
-
2011
- 2011-03-28 CY CY20111100330T patent/CY1113088T1/el unknown
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