JP2007514161A5 - - Google Patents
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- Publication number
- JP2007514161A5 JP2007514161A5 JP2006543771A JP2006543771A JP2007514161A5 JP 2007514161 A5 JP2007514161 A5 JP 2007514161A5 JP 2006543771 A JP2006543771 A JP 2006543771A JP 2006543771 A JP2006543771 A JP 2006543771A JP 2007514161 A5 JP2007514161 A5 JP 2007514161A5
- Authority
- JP
- Japan
- Prior art keywords
- flow
- fluid
- interface
- sample
- induction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000012530 fluid Substances 0.000 claims description 160
- 238000000034 method Methods 0.000 claims description 50
- 230000006698 induction Effects 0.000 claims description 45
- 238000001514 detection method Methods 0.000 claims description 20
- 230000001939 inductive effect Effects 0.000 claims description 17
- 230000008859 change Effects 0.000 claims description 3
- 210000004027 cell Anatomy 0.000 description 36
- 238000002198 surface plasmon resonance spectroscopy Methods 0.000 description 22
- 230000003993 interaction Effects 0.000 description 10
- 230000003287 optical effect Effects 0.000 description 10
- 230000004044 response Effects 0.000 description 9
- 238000004590 computer program Methods 0.000 description 7
- 238000004611 spectroscopical analysis Methods 0.000 description 7
- 238000003384 imaging method Methods 0.000 description 6
- 239000003446 ligand Substances 0.000 description 5
- 238000012360 testing method Methods 0.000 description 5
- 238000010586 diagram Methods 0.000 description 4
- 239000012491 analyte Substances 0.000 description 3
- 238000012544 monitoring process Methods 0.000 description 3
- 238000004416 surface enhanced Raman spectroscopy Methods 0.000 description 3
- 206010070834 Sensitisation Diseases 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 238000004630 atomic force microscopy Methods 0.000 description 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 2
- 229910052737 gold Inorganic materials 0.000 description 2
- 239000010931 gold Substances 0.000 description 2
- 238000001028 reflection method Methods 0.000 description 2
- 230000008313 sensitization Effects 0.000 description 2
- 230000001235 sensitizing effect Effects 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 239000004094 surface-active agent Substances 0.000 description 2
- GNFTZDOKVXKIBK-UHFFFAOYSA-N 3-(2-methoxyethoxy)benzohydrazide Chemical compound COCCOC1=CC=CC(C(=O)NN)=C1 GNFTZDOKVXKIBK-UHFFFAOYSA-N 0.000 description 1
- 238000012935 Averaging Methods 0.000 description 1
- FGUUSXIOTUKUDN-IBGZPJMESA-N C1(=CC=CC=C1)N1C2=C(NC([C@H](C1)NC=1OC(=NN=1)C1=CC=CC=C1)=O)C=CC=C2 Chemical compound C1(=CC=CC=C1)N1C2=C(NC([C@H](C1)NC=1OC(=NN=1)C1=CC=CC=C1)=O)C=CC=C2 FGUUSXIOTUKUDN-IBGZPJMESA-N 0.000 description 1
- 238000000018 DNA microarray Methods 0.000 description 1
- 238000002835 absorbance Methods 0.000 description 1
- 238000004082 amperometric method Methods 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 238000001210 attenuated total reflectance infrared spectroscopy Methods 0.000 description 1
- 239000011324 bead Substances 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 238000011088 calibration curve Methods 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 238000002848 electrochemical method Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000000105 evaporative light scattering detection Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000003100 immobilizing effect Effects 0.000 description 1
- 238000005305 interferometry Methods 0.000 description 1
- 238000012923 label-free technique Methods 0.000 description 1
- 238000002372 labelling Methods 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 238000000386 microscopy Methods 0.000 description 1
- 230000004001 molecular interaction Effects 0.000 description 1
- 230000010287 polarization Effects 0.000 description 1
- 238000004313 potentiometry Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52895003P | 2003-12-10 | 2003-12-10 | |
| US60/528,950 | 2003-12-10 | ||
| SE0303319-8 | 2003-12-10 | ||
| SE0303319A SE0303319D0 (sv) | 2003-12-10 | 2003-12-10 | Sample flow positioning method and analytical system using the method |
| PCT/SE2004/001825 WO2005057186A1 (en) | 2003-12-10 | 2004-12-08 | Sample flow positioning method and analytical system using the method |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007514161A JP2007514161A (ja) | 2007-05-31 |
| JP2007514161A5 true JP2007514161A5 (https=) | 2011-05-26 |
| JP4870571B2 JP4870571B2 (ja) | 2012-02-08 |
Family
ID=34680754
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006543771A Expired - Fee Related JP4870571B2 (ja) | 2003-12-10 | 2004-12-08 | サンプルの流れの位置決め法及び該方法を用いた分析システム |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1692488B1 (https=) |
| JP (1) | JP4870571B2 (https=) |
| AT (1) | ATE517329T1 (https=) |
| AU (1) | AU2004297498B2 (https=) |
| WO (1) | WO2005057186A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130295587A1 (en) * | 2011-01-24 | 2013-11-07 | Ge Healthcare Bio-Sciences Ab | Method of coupling binding agents to a substrate surface |
| KR102102934B1 (ko) * | 2013-12-10 | 2020-04-21 | 일루미나, 인코포레이티드 | 생물학적 또는 화학적 분석을 위한 바이오센서들 및 이를 제조하기 위한 방법 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63262565A (ja) * | 1987-04-20 | 1988-10-28 | Hitachi Ltd | フロ−セル |
| US5716852A (en) * | 1996-03-29 | 1998-02-10 | University Of Washington | Microfabricated diffusion-based chemical sensor |
| US6200814B1 (en) * | 1998-01-20 | 2001-03-13 | Biacore Ab | Method and device for laminar flow on a sensing surface |
| EP1169122A2 (en) * | 1999-03-24 | 2002-01-09 | Torsana Biosensor A/S | Spatially directed interaction on a solid surface |
-
2004
- 2004-12-08 AT AT04801730T patent/ATE517329T1/de not_active IP Right Cessation
- 2004-12-08 JP JP2006543771A patent/JP4870571B2/ja not_active Expired - Fee Related
- 2004-12-08 AU AU2004297498A patent/AU2004297498B2/en not_active Ceased
- 2004-12-08 WO PCT/SE2004/001825 patent/WO2005057186A1/en not_active Ceased
- 2004-12-08 EP EP04801730A patent/EP1692488B1/en not_active Expired - Lifetime
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| JP2007514161A5 (https=) |