JP2007512273A - ベータ−3−アドレノセプター作用薬及びプロスタグランジン代謝に影響を及ぼす活性物質から成る医薬組成物 - Google Patents
ベータ−3−アドレノセプター作用薬及びプロスタグランジン代謝に影響を及ぼす活性物質から成る医薬組成物 Download PDFInfo
- Publication number
- JP2007512273A JP2007512273A JP2006540275A JP2006540275A JP2007512273A JP 2007512273 A JP2007512273 A JP 2007512273A JP 2006540275 A JP2006540275 A JP 2006540275A JP 2006540275 A JP2006540275 A JP 2006540275A JP 2007512273 A JP2007512273 A JP 2007512273A
- Authority
- JP
- Japan
- Prior art keywords
- urinary incontinence
- ethyl
- component
- hydroxy
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- YNCNZXJRRRALAJ-UHFFFAOYSA-N CC(C(c(cc1)ccc1O)O)NCCc(cc1)cc(Cl)c1OCC(O)=O Chemical compound CC(C(c(cc1)ccc1O)O)NCCc(cc1)cc(Cl)c1OCC(O)=O YNCNZXJRRRALAJ-UHFFFAOYSA-N 0.000 description 1
- QFMUIHJMDMGJAY-IAXKEJLGSA-N CCOC(COc1ccc(CCCC(C2)NC[C@@H](c3cc(Cl)ccc3)O)c2c1)=O Chemical compound CCOC(COc1ccc(CCCC(C2)NC[C@@H](c3cc(Cl)ccc3)O)c2c1)=O QFMUIHJMDMGJAY-IAXKEJLGSA-N 0.000 description 1
- HIZKIFDKLKNNJH-NRFANRHFSA-N CS(Nc(cc([C@H](CNC(CC1)CCN1c1ccc(CN(C(N2)=O)SC2=O)cc1)O)cc1)c1O)(=O)=O Chemical compound CS(Nc(cc([C@H](CNC(CC1)CCN1c1ccc(CN(C(N2)=O)SC2=O)cc1)O)cc1)c1O)(=O)=O HIZKIFDKLKNNJH-NRFANRHFSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10356112A DE10356112A1 (de) | 2003-11-27 | 2003-11-27 | Pharmazeutische Zusammensetzung aus einem Beta-3-Adrenozeptor-Agonisten und einem in den Prostglandinstoffwechsel eingreifendem Wirkstoff |
| PCT/EP2004/012896 WO2005060955A1 (de) | 2003-11-27 | 2004-11-13 | Pharmazeutische zusammensetzung aus einem beta-3-adrenozeptor-agonisten und einem in den prostaglandinstoffwechsel eingreifendem wirkstoff |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007512273A true JP2007512273A (ja) | 2007-05-17 |
| JP2007512273A5 JP2007512273A5 (enExample) | 2007-12-27 |
Family
ID=34609427
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006540275A Pending JP2007512273A (ja) | 2003-11-27 | 2004-11-13 | ベータ−3−アドレノセプター作用薬及びプロスタグランジン代謝に影響を及ぼす活性物質から成る医薬組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20050119239A1 (enExample) |
| EP (1) | EP1689382A1 (enExample) |
| JP (1) | JP2007512273A (enExample) |
| CA (1) | CA2546565A1 (enExample) |
| DE (1) | DE10356112A1 (enExample) |
| WO (1) | WO2005060955A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2006250888A1 (en) * | 2005-05-24 | 2006-11-30 | Avesthagen Limited | A method for the production of a monoclonal antibody to CD20 for the treatment of B-cell lymphoma |
| MXPA05008575A (es) * | 2005-08-12 | 2007-02-12 | Leopoldo Espinosa Abdala | Formulaciones farmaceuticas solidas sublinguales conteniendo meloxicam. |
| EP1769792A1 (de) * | 2005-09-30 | 2007-04-04 | Boehringer Ingelheim Pharma GmbH & Co.KG | Verwendung eines beta-3-Adrenozeptor-Agonisten zur Behandlung von Nieren- und Blasenbeschwerden |
| EP1974725A4 (en) * | 2006-01-10 | 2012-12-05 | Kissei Pharmaceutical | PREPARATION WITH DELAYED RELEASE AND METHOD OF MANUFACTURING THEREOF |
| EP1870102A1 (en) * | 2006-06-15 | 2007-12-26 | Alpex Pharma SA | Solid forms containing meloxicam with improved taste and process for their preparation |
| EP1947103A1 (en) | 2007-01-22 | 2008-07-23 | 4Sc Ag | Aryloxypropanolamines, methods of preparation thereof and use of aryloxypropanolamines as medicaments |
| US20090246273A1 (en) * | 2008-03-27 | 2009-10-01 | Al-Ghananeem Abeer M | Ketorolac Sublingual Spray for the Treatment of Pain |
| US20120244221A1 (en) * | 2010-07-08 | 2012-09-27 | Wellesley Pharmaceuticals, Llc | Extended-release formulation for reducing the frequency of urination and method of use thereof |
| US9532959B2 (en) | 2010-07-08 | 2017-01-03 | Wellesley Pharmaceuticals, Llc | Pharmaceutical formulation for reducing frequency of urination and method of use thereof |
| US20130323288A1 (en) | 2010-07-08 | 2013-12-05 | Wellesley Pharmaceuticals, Llc | Pharmaceutical formulation for bedwetting and method of use thereof |
| US10010514B2 (en) | 2010-07-08 | 2018-07-03 | Wellesley Pharmaceuticals, Llc | Pharmaceutical formulation for reducing frequency of urination and method of use thereof |
| US9415048B2 (en) | 2010-07-08 | 2016-08-16 | Wellesley Pharmaceuticals, Llc | Pharmaceutical formulation for reducing frequency of urination and method of use thereof |
| US20120237574A1 (en) * | 2010-07-08 | 2012-09-20 | Wellesley Pharmaceuticals, Llc | Delayed-release formulation for reducing the frequency of urination and method of use thereof |
| US10105330B2 (en) | 2012-01-04 | 2018-10-23 | Wellesley Pharmaceuticals, Llc | Extended, delayed and immediate release formulation method of manufacturing and use thereof |
| SG11201500410XA (en) | 2012-01-04 | 2015-04-29 | Wellesley Pharmaceuticals Llc | Delayed-release formulation for reducing the frequency of urination and method of use thereof |
| BR112014016661A8 (pt) | 2012-01-04 | 2017-07-04 | Wellesley Pharmaceuticals Llc | formulação de liberação prolongada para reduzir a frequência de urinação e método de uso da mesma |
| US10278925B2 (en) | 2012-01-04 | 2019-05-07 | Wellesley Pharmaceuticals, Llc | Delayed-release formulations, methods of making and use thereof |
| US10792326B2 (en) | 2013-06-28 | 2020-10-06 | Wellesley Pharmaceuticals, Llc | Pharmaceutical formulation for bedwetting and method of use thereof |
| US10105328B2 (en) | 2014-06-06 | 2018-10-23 | Wellesley Pharmaceuticals, Llc | Composition for reducing frequency of urination, method of making and use thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000002846A1 (fr) * | 1998-07-08 | 2000-01-20 | Kissei Pharmaceutical Co., Ltd. | Derives d'acide phenoxyacetique et compositions medicinales contenant lesdits derives |
| JP2001502302A (ja) * | 1996-09-19 | 2001-02-20 | アメリカン・ホーム・プロダクツ・コーポレイション | 尿失禁を治療する方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5043358A (en) * | 1986-03-04 | 1991-08-27 | Bristol-Myers Squibb Company | Gastroprotective process |
| US4965065A (en) * | 1986-04-29 | 1990-10-23 | Bristol-Myers Squibb Company | Gastroprotective process and compositions |
| US5260333A (en) * | 1986-08-08 | 1993-11-09 | Bristol Myers Squibb Company | Effect of a combination of a terbutaline, diphenhydramine and ranitidine composition on gastrointestinal injury produced by nonsteroidal anti-inflammatory compositions |
| EP0321613A1 (en) * | 1987-12-18 | 1989-06-28 | Bristol-Myers Company | The effect of a combination of a beta-adrenergic agonist and certain histamine H1- and/or H2-receptor blockers on gastrointestinal injury produced by nonsteroidal anti-inflammatory compositions |
| DE19940944B4 (de) * | 1999-08-31 | 2006-10-12 | Grünenthal GmbH | Retardierte, orale, pharmazeutische Darreichungsformen |
| AU2001286557A1 (en) * | 2000-08-23 | 2002-03-04 | Merck Frosst Canada And Co. | Method of treating or preventing urinary incontinence using prostanoid ep1 receptor antagonists |
| DE10225315A1 (de) * | 2002-06-06 | 2003-12-24 | Gruenenthal Gmbh | Wirkstoffsalze und Ester von 1-Dimethylamino-3-(3-methoxy-phenyl)-2-methyl- pentan-3-ol und 3-(3-Dimethylamino-1-ethyl-1-hydroxy-2-methyl- propyl)-phenol |
| EP1424079A1 (en) * | 2002-11-27 | 2004-06-02 | Boehringer Ingelheim International GmbH | Combination of a beta-3-receptor agonist and of a reuptake inhibitor of serotonin and/or norepinephrine |
-
2003
- 2003-11-27 DE DE10356112A patent/DE10356112A1/de not_active Withdrawn
-
2004
- 2004-11-13 CA CA002546565A patent/CA2546565A1/en not_active Abandoned
- 2004-11-13 JP JP2006540275A patent/JP2007512273A/ja active Pending
- 2004-11-13 EP EP04797878A patent/EP1689382A1/de not_active Withdrawn
- 2004-11-13 WO PCT/EP2004/012896 patent/WO2005060955A1/de not_active Ceased
- 2004-11-17 US US10/990,979 patent/US20050119239A1/en not_active Abandoned
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001502302A (ja) * | 1996-09-19 | 2001-02-20 | アメリカン・ホーム・プロダクツ・コーポレイション | 尿失禁を治療する方法 |
| WO2000002846A1 (fr) * | 1998-07-08 | 2000-01-20 | Kissei Pharmaceutical Co., Ltd. | Derives d'acide phenoxyacetique et compositions medicinales contenant lesdits derives |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005060955A1 (de) | 2005-07-07 |
| CA2546565A1 (en) | 2005-07-07 |
| DE10356112A1 (de) | 2005-06-23 |
| US20050119239A1 (en) | 2005-06-02 |
| EP1689382A1 (de) | 2006-08-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20071112 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20071112 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20101122 |
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| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20110418 |