JP2007509941A - ラクトース無水物を用いる吸入医薬製剤およびその投与方法 - Google Patents

ラクトース無水物を用いる吸入医薬製剤およびその投与方法 Download PDF

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Publication number
JP2007509941A
JP2007509941A JP2006538128A JP2006538128A JP2007509941A JP 2007509941 A JP2007509941 A JP 2007509941A JP 2006538128 A JP2006538128 A JP 2006538128A JP 2006538128 A JP2006538128 A JP 2006538128A JP 2007509941 A JP2007509941 A JP 2007509941A
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JP
Japan
Prior art keywords
lactose
inhaler
medicament
pharmaceutical formulation
formulation
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Pending
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JP2006538128A
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English (en)
Japanese (ja)
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JP2007509941A5 (enExample
Inventor
ドーソン，ミシェル，エル．
ロシュ，トレヴォア，シー．
ウィッテイカー，マーク
チダバエンズィ，オーウェン，チゾーラ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
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Glaxo Group Ltd
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Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of JP2007509941A publication Critical patent/JP2007509941A/ja
Publication of JP2007509941A5 publication Critical patent/JP2007509941A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2006538128A 2003-10-28 2004-10-22 ラクトース無水物を用いる吸入医薬製剤およびその投与方法 Pending JP2007509941A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51507703P 2003-10-28 2003-10-28
PCT/US2004/035129 WO2005044187A2 (en) 2003-10-28 2004-10-22 Inhalable pharmaceutical formulations employing lactose anhydrate and methods of administering the same

Publications (2)

Publication Number Publication Date
JP2007509941A true JP2007509941A (ja) 2007-04-19
JP2007509941A5 JP2007509941A5 (enExample) 2007-07-12

Family

ID=34572801

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006538128A Pending JP2007509941A (ja) 2003-10-28 2004-10-22 ラクトース無水物を用いる吸入医薬製剤およびその投与方法

Country Status (6)

Country Link
US (1) US20070053843A1 (enExample)
EP (1) EP1686960A4 (enExample)
JP (1) JP2007509941A (enExample)
CA (1) CA2543482A1 (enExample)
IL (1) IL175032A0 (enExample)
WO (1) WO2005044187A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015046489A1 (ja) 2013-09-30 2015-04-02 第一三共株式会社 スプレードライ法を用いたＤ－マンニトールα型結晶の選択的製造方法
JP2016519123A (ja) * 2013-04-29 2016-06-30 サノフィ・ソシエテ・アノニム 吸入可能な医薬組成物およびそれらを収容した吸入器デバイス

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GB0501956D0 (en) * 2005-01-31 2005-03-09 Arrow Internat Nebulizer formulation
GB0520794D0 (en) * 2005-10-12 2005-11-23 Innovata Biomed Ltd Inhaler
CN101744792B (zh) * 2008-12-17 2013-04-17 张凯 氟替卡松丙酸酯和沙美特罗昔萘酸酯复方干粉吸入剂及其制备工艺
US9925282B2 (en) 2009-01-29 2018-03-27 The General Hospital Corporation Cromolyn derivatives and related methods of imaging and treatment
TR200909788A2 (tr) * 2009-12-25 2011-07-21 Bi̇lgi̇ç Mahmut Tiotropyum içeren inhalasyona uygun kuru toz formülasyonu
US8834931B2 (en) 2009-12-25 2014-09-16 Mahmut Bilgic Dry powder formulation containing tiotropium for inhalation
TR201000685A2 (tr) * 2010-01-29 2011-08-22 Bi̇lgi̇ç Mahmut Salmeterol ve flutikazon içeren farmasötik preparatlar.
EP2533765A2 (en) * 2010-01-29 2012-12-19 Mahmut Bilgic Pharmaceutical compositions comprising formoterol and mometasone
WO2014007771A2 (en) 2012-07-05 2014-01-09 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Inhalation compositions comprising muscarinic receptor antagonist
US10111957B2 (en) 2012-07-05 2018-10-30 Arven Ilac Snayi ve Ticaret A.S. Inhalation compositions comprising glucose anhydrous
US20150165037A1 (en) * 2012-07-05 2015-06-18 Arven llac Sanayi Ve Ticaret A.S. Inhalation compositions comprising corticosteroid and sorbitol
CN106102737B (zh) * 2013-10-22 2019-06-14 综合医院公司 色甘酸衍生物以及成像和治疗的相关方法
WO2016037166A1 (en) * 2014-09-07 2016-03-10 Yu Zhang Novel anti-oxidant compositions and methods of delivery
MX392636B (es) 2014-10-31 2025-03-24 Glaxosmithkline Ip Dev Ltd Formulacion en polvo.
CN116889562A (zh) 2016-08-31 2023-10-17 通用医疗公司 与神经退行性疾病相关的神经炎症中的巨噬细胞/小胶质细胞
MX2021006869A (es) 2018-12-10 2021-07-02 Massachusetts Gen Hospital Esteres de cromolin y usos de los mismos.
WO2021207060A1 (en) 2020-04-06 2021-10-14 The General Hospital Corporation Methods of treatment of coronavirus-induced inflammation conditions

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998050015A1 (en) * 1997-05-07 1998-11-12 Pharlyse, Societe Anonyme Dry powder inhaler excipient, process for its preparation and pharmaceutical compositions containing it
JP2000510100A (ja) * 1996-03-23 2000-08-08 ウエスト、ファルマシューティカル、サービシズ、ドラッグ、デリバリー、アンド、クリニカル、リサーチ、センター、リミテッド 医薬物質の肺送達のためのポリサッカライド微小球

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US4778054A (en) * 1982-10-08 1988-10-18 Glaxo Group Limited Pack for administering medicaments to patients
FI88112C (fi) * 1985-07-30 1993-04-13 Glaxo Group Ltd Anordning foer administrering av laekemedel till patienter
SK280967B6 (sk) * 1990-03-02 2000-10-09 Glaxo Group Limited Inhalačný prístroj
GB9004781D0 (en) * 1990-03-02 1990-04-25 Glaxo Group Ltd Device
US6536427B2 (en) * 1990-03-02 2003-03-25 Glaxo Group Limited Inhalation device
PE44995A1 (es) * 1994-01-27 1995-12-18 Schering Corp Furoato de mometasona para el tratamiento de las enfermedades pulmonares y de las vias respiratorias
GB9404945D0 (en) * 1994-03-15 1994-04-27 Glaxo Group Ltd Pharmaceutical composition
TR199701167T1 (xx) * 1995-04-14 1998-03-21 Glaxo Wellcome Inc. Albuterol i�in �l��lm�� doz inhaleri.
AP979A (en) * 1995-04-14 2001-06-28 Glaxo Wellcome Inc Metered dose imhaler for salmeterol.
SK139197A3 (en) * 1995-04-14 1998-04-08 Glaxo Wellcome Inc Metered dose inhaler for beclomethasone dipropionate
EE04004B1 (et) * 1995-04-14 2003-04-15 Glaxo Wellcome Inc. Flutikasoonpropionaati doseeriv inhalaator
US6258341B1 (en) * 1995-04-14 2001-07-10 Inhale Therapeutic Systems, Inc. Stable glassy state powder formulations
GB9626960D0 (en) * 1996-12-27 1997-02-12 Glaxo Group Ltd Valve for aerosol container
GB9700226D0 (en) * 1997-01-08 1997-02-26 Glaxo Group Ltd Inhalation device
US6495167B2 (en) * 1997-03-20 2002-12-17 Schering Corporation Preparation of powder agglomerates
PL192441B1 (pl) * 1997-03-20 2006-10-31 Schering Corp Sposób wytwarzania aglomeratów i postać dawkowania środka farmakologicznie aktywnego
TW533865U (en) * 1997-06-10 2003-05-21 Glaxo Group Ltd Dispenser for dispensing medicament and actuation indicating device
GB2329939A (en) * 1997-06-26 1999-04-07 Glaxo Group Ltd Self-lubricating valve stem for aerosol containers
ATE382386T1 (de) * 1998-11-13 2008-01-15 Jagotec Ag Multidosis-trockenpulverinhalator mit pulverreservoir
US6390291B1 (en) * 1998-12-18 2002-05-21 Smithkline Beecham Corporation Method and package for storing a pressurized container containing a drug
MXPA03007908A (es) * 2000-02-17 2004-12-06 Teva Pharma Una formulacion farmaceutica estable que comprende una modificacion de torsemida ii.

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000510100A (ja) * 1996-03-23 2000-08-08 ウエスト、ファルマシューティカル、サービシズ、ドラッグ、デリバリー、アンド、クリニカル、リサーチ、センター、リミテッド 医薬物質の肺送達のためのポリサッカライド微小球
WO1998050015A1 (en) * 1997-05-07 1998-11-12 Pharlyse, Societe Anonyme Dry powder inhaler excipient, process for its preparation and pharmaceutical compositions containing it

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016519123A (ja) * 2013-04-29 2016-06-30 サノフィ・ソシエテ・アノニム 吸入可能な医薬組成物およびそれらを収容した吸入器デバイス
WO2015046489A1 (ja) 2013-09-30 2015-04-02 第一三共株式会社 スプレードライ法を用いたＤ－マンニトールα型結晶の選択的製造方法

Also Published As

Publication number Publication date
CA2543482A1 (en) 2005-05-19
US20070053843A1 (en) 2007-03-08
EP1686960A2 (en) 2006-08-09
WO2005044187A3 (en) 2006-03-23
WO2005044187A2 (en) 2005-05-19
IL175032A0 (en) 2008-04-13
EP1686960A4 (en) 2007-03-07

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