JP2007509941A - ラクトース無水物を用いる吸入医薬製剤およびその投与方法 - Google Patents

ラクトース無水物を用いる吸入医薬製剤およびその投与方法 Download PDF

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Publication number
JP2007509941A
JP2007509941A JP2006538128A JP2006538128A JP2007509941A JP 2007509941 A JP2007509941 A JP 2007509941A JP 2006538128 A JP2006538128 A JP 2006538128A JP 2006538128 A JP2006538128 A JP 2006538128A JP 2007509941 A JP2007509941 A JP 2007509941A
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JP
Japan
Prior art keywords
lactose
inhaler
medicament
pharmaceutical formulation
formulation
Prior art date
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Pending
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JP2006538128A
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English (en)
Japanese (ja)
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JP2007509941A5 (enExample
Inventor
ドーソン，ミシェル，エル．
ロシュ，トレヴォア，シー．
ウィッテイカー，マーク
チダバエンズィ，オーウェン，チゾーラ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
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Glaxo Group Ltd
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Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of JP2007509941A publication Critical patent/JP2007509941A/ja
Publication of JP2007509941A5 publication Critical patent/JP2007509941A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2006538128A 2003-10-28 2004-10-22 ラクトース無水物を用いる吸入医薬製剤およびその投与方法 Pending JP2007509941A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51507703P 2003-10-28 2003-10-28
PCT/US2004/035129 WO2005044187A2 (en) 2003-10-28 2004-10-22 Inhalable pharmaceutical formulations employing lactose anhydrate and methods of administering the same

Publications (2)

Publication Number Publication Date
JP2007509941A true JP2007509941A (ja) 2007-04-19
JP2007509941A5 JP2007509941A5 (enExample) 2007-07-12

Family

ID=34572801

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006538128A Pending JP2007509941A (ja) 2003-10-28 2004-10-22 ラクトース無水物を用いる吸入医薬製剤およびその投与方法

Country Status (6)

Country Link
US (1) US20070053843A1 (enExample)
EP (1) EP1686960A4 (enExample)
JP (1) JP2007509941A (enExample)
CA (1) CA2543482A1 (enExample)
IL (1) IL175032A0 (enExample)
WO (1) WO2005044187A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015046489A1 (ja) 2013-09-30 2015-04-02 第一三共株式会社 スプレードライ法を用いたＤ－マンニトールα型結晶の選択的製造方法
JP2016519123A (ja) * 2013-04-29 2016-06-30 サノフィ・ソシエテ・アノニム 吸入可能な医薬組成物およびそれらを収容した吸入器デバイス

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GB0501956D0 (en) * 2005-01-31 2005-03-09 Arrow Internat Nebulizer formulation
GB0520794D0 (en) * 2005-10-12 2005-11-23 Innovata Biomed Ltd Inhaler
CN101744792B (zh) * 2008-12-17 2013-04-17 张凯 氟替卡松丙酸酯和沙美特罗昔萘酸酯复方干粉吸入剂及其制备工艺
US9925282B2 (en) 2009-01-29 2018-03-27 The General Hospital Corporation Cromolyn derivatives and related methods of imaging and treatment
TR200909788A2 (tr) * 2009-12-25 2011-07-21 Bi̇lgi̇ç Mahmut Tiotropyum içeren inhalasyona uygun kuru toz formülasyonu
US8834931B2 (en) 2009-12-25 2014-09-16 Mahmut Bilgic Dry powder formulation containing tiotropium for inhalation
EP2533765A2 (en) * 2010-01-29 2012-12-19 Mahmut Bilgic Pharmaceutical compositions comprising formoterol and mometasone
TR201000685A2 (tr) * 2010-01-29 2011-08-22 Bi̇lgi̇ç Mahmut Salmeterol ve flutikazon içeren farmasötik preparatlar.
US10111957B2 (en) 2012-07-05 2018-10-30 Arven Ilac Snayi ve Ticaret A.S. Inhalation compositions comprising glucose anhydrous
WO2014007770A2 (en) * 2012-07-05 2014-01-09 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Inhalation compositions comprising corticosteroid and sorbitol
US10105316B2 (en) 2012-07-05 2018-10-23 Arven llac Sanayi Ve Ticaret A.S. Inhalation compositions comprising muscarinic receptor antagonist
AU2014340182B2 (en) * 2013-10-22 2019-05-23 The General Hospital Corporation Cromolyn derivatives and related methods of imaging and treatment
WO2016037166A1 (en) * 2014-09-07 2016-03-10 Yu Zhang Novel anti-oxidant compositions and methods of delivery
AU2015338717B2 (en) 2014-10-31 2018-12-20 Glaxosmithkline Intellectual Property Development Limited Powder formulation
US20190240194A1 (en) 2016-08-31 2019-08-08 The General Hospital Corporation Macrophages/microglia in neuro-inflammation associated with neurodegenerative diseases
US12383528B2 (en) 2018-12-10 2025-08-12 The General Hospital Corporation Cromolyn esters and uses thereof
WO2021207060A1 (en) 2020-04-06 2021-10-14 The General Hospital Corporation Methods of treatment of coronavirus-induced inflammation conditions
US12612391B2 (en) 2020-12-28 2026-04-28 The General Hospital Corporation Cromolyn derivatives and uses thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998050015A1 (en) * 1997-05-07 1998-11-12 Pharlyse, Societe Anonyme Dry powder inhaler excipient, process for its preparation and pharmaceutical compositions containing it
JP2000510100A (ja) * 1996-03-23 2000-08-08 ウエスト、ファルマシューティカル、サービシズ、ドラッグ、デリバリー、アンド、クリニカル、リサーチ、センター、リミテッド 医薬物質の肺送達のためのポリサッカライド微小球

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US4778054A (en) * 1982-10-08 1988-10-18 Glaxo Group Limited Pack for administering medicaments to patients
AU591152B2 (en) * 1985-07-30 1989-11-30 Glaxo Group Limited Devices for administering medicaments to patients
SK280968B6 (sk) * 1990-03-02 2000-10-09 Glaxo Group Limited Balenie medikamentu na použite v inhalačnom prístroji
GB9004781D0 (en) * 1990-03-02 1990-04-25 Glaxo Group Ltd Device
US6536427B2 (en) * 1990-03-02 2003-03-25 Glaxo Group Limited Inhalation device
PE44995A1 (es) * 1994-01-27 1995-12-18 Schering Corp Furoato de mometasona para el tratamiento de las enfermedades pulmonares y de las vias respiratorias
GB9404945D0 (en) * 1994-03-15 1994-04-27 Glaxo Group Ltd Pharmaceutical composition
DE69622166T2 (de) * 1995-04-14 2003-04-03 Smithkline Beecham Corp., Philadelphia Dosierinhalator für albuterol
CA2218179A1 (en) * 1995-04-14 1996-10-17 Glaxo Wellcome Inc. Metered dose inhaler for beclomethasone dipropionate
MX9707862A (es) * 1995-04-14 1997-11-29 Glaxo Wellcome Inc Inhalador de dosis medida para el propionato de fluticasona.
US6258341B1 (en) * 1995-04-14 2001-07-10 Inhale Therapeutic Systems, Inc. Stable glassy state powder formulations
EP1366777B1 (en) * 1995-04-14 2005-06-15 SmithKline Beecham Corporation Metered dose inhaler for salmeterol
GB9626960D0 (en) * 1996-12-27 1997-02-12 Glaxo Group Ltd Valve for aerosol container
GB9700226D0 (en) * 1997-01-08 1997-02-26 Glaxo Group Ltd Inhalation device
US6495167B2 (en) * 1997-03-20 2002-12-17 Schering Corporation Preparation of powder agglomerates
EP1393721B1 (en) * 1997-03-20 2008-11-26 Schering Corporation Dosage form of powder agglomerates
TW533865U (en) * 1997-06-10 2003-05-21 Glaxo Group Ltd Dispenser for dispensing medicament and actuation indicating device
GB2329939A (en) * 1997-06-26 1999-04-07 Glaxo Group Ltd Self-lubricating valve stem for aerosol containers
CN1150895C (zh) * 1998-11-13 2004-05-26 杰格研究股份公司 用于吸入给药的干粉
US6390291B1 (en) * 1998-12-18 2002-05-21 Smithkline Beecham Corporation Method and package for storing a pressurized container containing a drug
ES2193007T3 (es) * 2000-02-17 2004-11-01 Teva Pharmaceutical Industries Ltd. Formulacion farmaceutica estable que comprende la modificacion ii de la torsemida.

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000510100A (ja) * 1996-03-23 2000-08-08 ウエスト、ファルマシューティカル、サービシズ、ドラッグ、デリバリー、アンド、クリニカル、リサーチ、センター、リミテッド 医薬物質の肺送達のためのポリサッカライド微小球
WO1998050015A1 (en) * 1997-05-07 1998-11-12 Pharlyse, Societe Anonyme Dry powder inhaler excipient, process for its preparation and pharmaceutical compositions containing it

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016519123A (ja) * 2013-04-29 2016-06-30 サノフィ・ソシエテ・アノニム 吸入可能な医薬組成物およびそれらを収容した吸入器デバイス
WO2015046489A1 (ja) 2013-09-30 2015-04-02 第一三共株式会社 スプレードライ法を用いたＤ－マンニトールα型結晶の選択的製造方法

Also Published As

Publication number Publication date
EP1686960A4 (en) 2007-03-07
CA2543482A1 (en) 2005-05-19
EP1686960A2 (en) 2006-08-09
WO2005044187A2 (en) 2005-05-19
IL175032A0 (en) 2008-04-13
WO2005044187A3 (en) 2006-03-23
US20070053843A1 (en) 2007-03-08

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