JP2007509678A - 骨部位上の損傷組織の修復 - Google Patents
骨部位上の損傷組織の修復 Download PDFInfo
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- JP2007509678A JP2007509678A JP2006537406A JP2006537406A JP2007509678A JP 2007509678 A JP2007509678 A JP 2007509678A JP 2006537406 A JP2006537406 A JP 2006537406A JP 2006537406 A JP2006537406 A JP 2006537406A JP 2007509678 A JP2007509678 A JP 2007509678A
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- groove
- pad
- repair kit
- repair
- bone
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- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0065—Three-dimensional shapes toroidal, e.g. ring-shaped, doughnut-shaped
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0069—Three-dimensional shapes cylindrical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
- A61F2250/0037—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in height or in length
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/006—Additional features; Implant or prostheses properties not otherwise provided for modular
- A61F2250/0063—Nested prosthetic parts
Abstract
Description
本願では、以下において、損傷した軟骨組織の修復について言及する。損傷した組織は、損傷した表面骨自体を含む他のタイプの組織でありうることを理解すべきである。本願では、以下において、膝関節の軟骨組織の修復について言及するが、ここでも、本発明は、他の体の関節、及び、骨から構成される又は骨を組み込む体の他の臓器にも適用しうることを理解すべきである。
本発明の1つの面では、動物又は人間内の骨部位の表面における又は表面上にある損傷軟骨組織の修復に使用する修復キットを提供する。ここでは、骨部位から損傷軟骨組織が除去され、修復キットの移植の前に、溝が骨部位の周囲に且つ骨内に形成されている。修復キットは、損傷軟組織が除去された骨部位の少なくとも一部を占有するような形状及び寸法にされる生体適応可能材料のパッドと、パッドの周囲に、溝の形状に対応するアレイで取り付けられ、溝内に導入され且つ溝内で固定されるようパッドの平面から離れるよう延在することを意図する細長い接続部と、溝内に接続部の少なくとも一部を固定し、それにより、骨部位の一部内にパッドを保持するために溝の深さ方向にスライド可能な保持素子を含む。
改良された装置は、体内に移植されると永久的又は生体吸収性である織り又は不織り材料から形成されたパッドを含み、このパッドは、単繊維糸又は多繊維糸から形成された編み糸、又は、体内に移植されると永久的又は生体吸収性の材料である縫合糸に接続される。糸は、パッドに、その物質を介して、パッドの表面と平行に、又は、パッドの物質を介して、パッドの表面に対して実質的に垂直な又は傾斜された方向に(図1及び2に示すように)接続されることが可能であり、糸端(ループ或いは単一端の形であっても、又は、両方の形であってもよい)は、パッドの周囲付近から出て、その出る場所から例えば30ミリメートル(これより長くても短くてもよい)の距離で飛び出し、それにより、パッドを、上述のように前処理された修復部位を取り囲むよう前処理された細い溝内にパッドを固定する手段を形成する。リング(溝の形状に適合する)は、溝内に嵌め込まれ、これは、必ずしも円形である必要はなく、このようなリングは、生体適合性金属、生体吸収性材料、又は、任意の他の好適な材料から形成され、また、リングは、一体式の構成要素であるか或いはセグメントから構成されうることが可能であり、また、リングは、溝内に押し込まれ、それにより、その表面と溝の2つの骨表面の両方間の糸を捕捉し、それにより、パッドを修復部位内に固定する。
図1及び2を最初に参照するに、本発明の修復キットには参照符号10が付され、この修復キットは、動物又は人間の骨部位の表面にある又は表面上にある軟骨組織といった損傷した組織の修復に使用することを目的とする。修復キットの移植の前に、損傷した組織が部位から取り除かれ、その部位の周り及び骨に溝が形成される。損傷組織の除去と溝の形成の順序は限定的ではなく、何れも、手術時に外科医が選択しうる機器に依存して、前に行うことが可能である。修復キットを受け入れる準備が整った骨部位の前処理は、国際公開第01/39694号により詳細に記載される以下の方法によって、例示的にのみ、行われうる。
Claims (21)
- 動物又は人間内の骨部位(20)の表面における又は表面上にある損傷軟骨組織の修復に使用する修復キット(10)であって、
前記骨部位から前記損傷軟骨組織が除去され、前記修復キットの移植の前に、溝(25)が前記骨部位の周囲に且つ前記骨内に形成され、
前記修復キットは、
前記損傷軟組織が除去された前記骨部位の少なくとも一部を占有するような形状及び寸法にされる生体適応可能材料のパッド(11)と、
前記パッドの周囲に、前記溝の形状に対応するアレイで取り付けられ、前記溝内に導入され且つ前記溝内で固定されるよう前記パッドの平面から離れるよう延在することを意図する細長い接続部(14)と、
前記溝内に前記接続部の少なくとも一部を固定し、それにより、前記骨部位の前記一部内に前記パッドを保持するために前記溝の深さ方向にスライド可能な保持素子(26)と、
を含む修復キット。 - 前記パッドには、移植の前に、軟骨細胞、又は、軟骨形成細胞がシードされる請求項1記載の修復キット。
- 前記細長い接続部は、前記パッドの周囲において又は周囲の付近で前記パッドを通される又は「縫われる」1つ以上の弾性引張り素子から形成され、また、前記溝により受容されるよう前記パッドの平面に略垂直に延在可能であり、隣接する素子は、前記溝における組織内殖を可能にするよう互いから間隔が置かれる請求項1又は2記載の修復キット。
- 単繊維、糸、又は編み糸が前記パッドの周囲に取り付けられ、前記パッドの下方向に略平行な長さのループで延在する請求項3記載の修復キット。
- 前記保持素子は、前記ループの端に予め取り付けられ、それにより、前記溝内への前記保持素子の下方向動作が、前記ループを、前記パッドが前記骨部位内に又は前記骨部位において受容され且つ固定されるまで下方向に引っ張る請求項4記載の修復キット。
- 前記ループの端は、最初に、導入器工具の使用を含む別の手段により前記溝内に入れられ、次に、前記保持素子は、前記ループの端に係合し、前記ループの端を前記溝内の固定係合まで下方向に引っ張るよう前記溝の下方向に付勢可能である請求項4記載の修復キット。
- 前記保持素子は、前記溝の深さ方向にスライド可能であり、平面図で見た時に前記溝の形状の少なくとも一部に略対応する形状を有するよう予め形成される請求項1乃至6のうちいずれか一項記載の修復キット。
- 前記保持素子は、前記溝内への導入の前に、必要とされる形状となるよう変形可能である請求項1乃至6のうちいずれか一項記載の修復キット。
- 前記保持素子は、リング又は略完全なリングを含み、
前記リングは、前記修復キットの製造時に、又は、前記移植方法の間に、前記細長い接続素子の前記ループの端を「縫われる」又は接続されることが可能である請求項1乃至8のうちいずれか一項記載の修復キット。 - 前記パッドは、円形、三日月型、2つの直線の側部を有する部分円形、六角形、又は、骨部位の前処理の間に利用可能な空間を充填するよう互いに対して相互に嵌ることが可能な他の多数の面を有する形状である請求項1乃至9のうちいずれか一項記載の修復キット。
- 前記パッド、前記細長い接続部、及び、前記保持素子は、移植片供給装置(46)上で予め組み付けられ、前記骨部位が前処理されると外科医により使用されることが可能である請求項1乃至10のうちいずれか一項記載の修復キット。
- 前記供給装置は、該供給装置の少なくとも1つの端において中空であり、
前記少なくとも1つの端に、前記保持素子と前記パッドが、前記前処理された骨部位及び前記周囲溝に対して与えることができるよう取り付けられる請求項11記載の修復キット。 - 前記細長い接続部は、前記供給装置の前記中空端の外面上に配置される請求項12記載の修復キット。
- 前記細長い接続部は、解放可能な保持構成により所定位置に保持される請求項12又は13記載の修復キット。
- 前記保持構成は、前記接続部と、前記供給装置の前記中空端の前記外面を係合するよう弱接着テープ等のバンド、又は、薄い管状バンドを含む請求項14記載の修復キット。
- 前記供給装置は、該供給装置の遠隔端において、手動で動作可能な移植工具ハンドルが着脱可能に取付け可能である請求項11乃至15のうちいずれか一項記載の修復キット。
- 前記工具ハンドルと前記供給装置との間の結合は、前記外科医による操作時に、前記工具の回転動作を、そのような回転動作を前記供給装置に伝達することなく、可能にする軸受けを含む請求項16記載の修復キット。
- 人間を含む動物における骨の表面における又は表面上にある損傷組織の修復のための方法であって、
前記損傷組織の少なくとも一部の周りに、前記損傷組織の下の骨内に延在する細い溝(25)を形成する段階と、
周りに前記溝が延在する組織を、少なくとも1つの生体適合可能置換材料の層(11)により置換する段階と、
前記材料から前記溝内に延在する保持手段(14、26)を使用することにより前記骨に前記材料を固定する段階と、
を有する方法。 - 前記溝は、リーマ装置により形成される請求項18記載の方法。
- 前記溝の深さは、置換される組織の厚さの少なくとも5倍である請求項19記載の方法。
- 請求項1乃至17のうちいずれか一項記載の修復キットを用いて動物又は人間の骨部位における損傷軟骨組織を修復する方法。
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GBGB0325141.0A GB0325141D0 (en) | 2003-10-28 | 2003-10-28 | Repair of damaged tissue on a bone site |
PCT/GB2004/004536 WO2005051242A1 (en) | 2003-10-28 | 2004-10-27 | Repair of damaged tissue on a bone site |
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- 2004-10-27 EP EP04791587A patent/EP1680050A1/en not_active Withdrawn
- 2004-10-27 JP JP2006537406A patent/JP2007509678A/ja active Pending
- 2004-10-27 WO PCT/GB2004/004536 patent/WO2005051242A1/en active Application Filing
- 2004-10-27 US US10/577,886 patent/US7632311B2/en not_active Expired - Fee Related
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Publication number | Priority date | Publication date | Assignee | Title |
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JP2011502703A (ja) * | 2007-11-16 | 2011-01-27 | スミス アンド ネフュー インコーポレーテッド | 環状リング移植片 |
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WO2005051242A1 (en) | 2005-06-09 |
AU2004292380A1 (en) | 2005-06-09 |
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EP1680050A1 (en) | 2006-07-19 |
GB0325141D0 (en) | 2003-12-03 |
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