JP2007509606A5 - - Google Patents
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- Publication number
- JP2007509606A5 JP2007509606A5 JP2006530584A JP2006530584A JP2007509606A5 JP 2007509606 A5 JP2007509606 A5 JP 2007509606A5 JP 2006530584 A JP2006530584 A JP 2006530584A JP 2006530584 A JP2006530584 A JP 2006530584A JP 2007509606 A5 JP2007509606 A5 JP 2007509606A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- polypeptide
- disease
- nucleic acid
- acid molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 48
- 229920001184 polypeptide Polymers 0.000 claims 47
- 102000004196 processed proteins & peptides Human genes 0.000 claims 46
- 150000007523 nucleic acids Chemical class 0.000 claims 36
- 108020004707 nucleic acids Proteins 0.000 claims 34
- 102000039446 nucleic acids Human genes 0.000 claims 34
- 201000010099 disease Diseases 0.000 claims 29
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 29
- 238000000034 method Methods 0.000 claims 22
- 150000001875 compounds Chemical class 0.000 claims 17
- 239000003446 ligand Substances 0.000 claims 11
- 230000000694 effects Effects 0.000 claims 10
- 239000000523 sample Substances 0.000 claims 9
- 210000004027 cell Anatomy 0.000 claims 6
- 108090000623 proteins and genes Proteins 0.000 claims 6
- 208000011580 syndromic disease Diseases 0.000 claims 6
- 210000001519 tissue Anatomy 0.000 claims 6
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 5
- 239000013068 control sample Substances 0.000 claims 5
- 238000003745 diagnosis Methods 0.000 claims 5
- 239000012634 fragment Substances 0.000 claims 5
- 230000035772 mutation Effects 0.000 claims 5
- 102000008186 Collagen Human genes 0.000 claims 4
- 108010035532 Collagen Proteins 0.000 claims 4
- 208000027530 Meniere disease Diseases 0.000 claims 4
- 108020004711 Nucleic Acid Probes Proteins 0.000 claims 4
- 206010064930 age-related macular degeneration Diseases 0.000 claims 4
- 125000003275 alpha amino acid group Chemical group 0.000 claims 4
- 230000003321 amplification Effects 0.000 claims 4
- 229920001436 collagen Polymers 0.000 claims 4
- 208000015181 infectious disease Diseases 0.000 claims 4
- 208000002780 macular degeneration Diseases 0.000 claims 4
- 238000003199 nucleic acid amplification method Methods 0.000 claims 4
- 239000002853 nucleic acid probe Substances 0.000 claims 4
- 239000008194 pharmaceutical composition Substances 0.000 claims 4
- 206010011005 corneal dystrophy Diseases 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 208000001517 late-onset retinal degeneration Diseases 0.000 claims 3
- 239000000203 mixture Substances 0.000 claims 3
- 238000012544 monitoring process Methods 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 208000024827 Alzheimer disease Diseases 0.000 claims 2
- 201000001320 Atherosclerosis Diseases 0.000 claims 2
- 208000023275 Autoimmune disease Diseases 0.000 claims 2
- 208000035143 Bacterial infection Diseases 0.000 claims 2
- 201000004569 Blindness Diseases 0.000 claims 2
- 201000001922 Chandler syndrome Diseases 0.000 claims 2
- 206010011878 Deafness Diseases 0.000 claims 2
- 206010012289 Dementia Diseases 0.000 claims 2
- 208000013558 Developmental Bone disease Diseases 0.000 claims 2
- 206010058314 Dysplasia Diseases 0.000 claims 2
- 206010016717 Fistula Diseases 0.000 claims 2
- 206010051066 Gastrointestinal stromal tumour Diseases 0.000 claims 2
- 208000007569 Giant Cell Tumors Diseases 0.000 claims 2
- 206010018364 Glomerulonephritis Diseases 0.000 claims 2
- 241000598436 Human T-cell lymphotropic virus Species 0.000 claims 2
- 206010061218 Inflammation Diseases 0.000 claims 2
- 241001465754 Metazoa Species 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 2
- 208000008589 Obesity Diseases 0.000 claims 2
- 208000030852 Parasitic disease Diseases 0.000 claims 2
- 208000018737 Parkinson disease Diseases 0.000 claims 2
- 206010072610 Skeletal dysplasia Diseases 0.000 claims 2
- 208000009205 Tinnitus Diseases 0.000 claims 2
- 208000036142 Viral infection Diseases 0.000 claims 2
- 206010047623 Vitamin C deficiency Diseases 0.000 claims 2
- 206010002022 amyloidosis Diseases 0.000 claims 2
- 230000000890 antigenic effect Effects 0.000 claims 2
- 208000007474 aortic aneurysm Diseases 0.000 claims 2
- 206010003246 arthritis Diseases 0.000 claims 2
- 208000027625 autoimmune inner ear disease Diseases 0.000 claims 2
- 208000022362 bacterial infectious disease Diseases 0.000 claims 2
- 238000009739 binding Methods 0.000 claims 2
- 230000015572 biosynthetic process Effects 0.000 claims 2
- 210000000988 bone and bone Anatomy 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 230000022159 cartilage development Effects 0.000 claims 2
- 201000005217 chondroblastoma Diseases 0.000 claims 2
- 201000004180 corneal endothelial dystrophy Diseases 0.000 claims 2
- 230000007423 decrease Effects 0.000 claims 2
- 206010012601 diabetes mellitus Diseases 0.000 claims 2
- 210000003027 ear inner Anatomy 0.000 claims 2
- 230000003890 fistula Effects 0.000 claims 2
- 201000011243 gastrointestinal stromal tumor Diseases 0.000 claims 2
- 230000010370 hearing loss Effects 0.000 claims 2
- 231100000888 hearing loss Toxicity 0.000 claims 2
- 208000016354 hearing loss disease Diseases 0.000 claims 2
- 230000004054 inflammatory process Effects 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 230000004770 neurodegeneration Effects 0.000 claims 2
- 208000015122 neurodegenerative disease Diseases 0.000 claims 2
- 235000020824 obesity Nutrition 0.000 claims 2
- 201000008968 osteosarcoma Diseases 0.000 claims 2
- 239000013610 patient sample Substances 0.000 claims 2
- 210000004049 perilymph Anatomy 0.000 claims 2
- 208000010233 scurvy Diseases 0.000 claims 2
- 230000001225 therapeutic effect Effects 0.000 claims 2
- 231100000886 tinnitus Toxicity 0.000 claims 2
- 230000009261 transgenic effect Effects 0.000 claims 2
- 230000009385 viral infection Effects 0.000 claims 2
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 208000003923 Hereditary Corneal Dystrophies Diseases 0.000 claims 1
- 108010076504 Protein Sorting Signals Proteins 0.000 claims 1
- 201000007737 Retinal degeneration Diseases 0.000 claims 1
- 239000000556 agonist Substances 0.000 claims 1
- 125000000539 amino acid group Chemical group 0.000 claims 1
- 239000005557 antagonist Substances 0.000 claims 1
- 230000031018 biological processes and functions Effects 0.000 claims 1
- 239000012472 biological sample Substances 0.000 claims 1
- 239000003153 chemical reaction reagent Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 230000004064 dysfunction Effects 0.000 claims 1
- 230000006870 function Effects 0.000 claims 1
- 108020001507 fusion proteins Proteins 0.000 claims 1
- 102000037865 fusion proteins Human genes 0.000 claims 1
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 208000020082 intraepithelial neoplasia Diseases 0.000 claims 1
- 230000000813 microbial effect Effects 0.000 claims 1
- 244000005700 microbiome Species 0.000 claims 1
- 235000016709 nutrition Nutrition 0.000 claims 1
- 230000035764 nutrition Effects 0.000 claims 1
- 230000004258 retinal degeneration Effects 0.000 claims 1
- 238000012216 screening Methods 0.000 claims 1
- 239000000758 substrate Substances 0.000 claims 1
- 229960005486 vaccine Drugs 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0322998.6A GB0322998D0 (en) | 2003-10-01 | 2003-10-01 | Protein |
| PCT/GB2004/004197 WO2005033312A1 (en) | 2003-10-01 | 2004-10-01 | C1q related protein |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007509606A JP2007509606A (ja) | 2007-04-19 |
| JP2007509606A5 true JP2007509606A5 (https=) | 2007-11-22 |
Family
ID=29415312
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006530584A Abandoned JP2007509606A (ja) | 2003-10-01 | 2004-10-01 | Ｃ１ｑ関連タンパク質 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20070264251A1 (https=) |
| EP (1) | EP1668131A1 (https=) |
| JP (1) | JP2007509606A (https=) |
| AU (1) | AU2004278556A1 (https=) |
| CA (1) | CA2537326A1 (https=) |
| GB (1) | GB0322998D0 (https=) |
| IL (1) | IL174295A0 (https=) |
| WO (1) | WO2005033312A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT3687287T (pt) * | 2017-09-29 | 2023-11-03 | Regeneron Pharma | Roedores que expressam complexo c1q humanizado |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5702948A (en) * | 1995-02-02 | 1997-12-30 | The Trustees Of The University Of Pennsylvania | Saccular collagen and compositions and methods for making and using the same |
| AU2002255478A1 (en) * | 2001-01-10 | 2002-09-12 | Pe Corporation (Ny) | Kits, such as nucleic acid arrays, comprising a majority of human exons or transcripts, for detecting expression and other uses thereof |
| WO2003072827A1 (en) * | 2001-10-31 | 2003-09-04 | Children's Hospital Medical Center | Method for diagnosis and treatment of rheumatoid arthritis |
| WO2003087768A2 (en) * | 2002-04-12 | 2003-10-23 | Mitokor | Targets for therapeutic intervention identified in the mitochondrial proteome |
-
2003
- 2003-10-01 GB GBGB0322998.6A patent/GB0322998D0/en not_active Ceased
-
2004
- 2004-10-01 EP EP04768737A patent/EP1668131A1/en not_active Withdrawn
- 2004-10-01 WO PCT/GB2004/004197 patent/WO2005033312A1/en not_active Ceased
- 2004-10-01 CA CA002537326A patent/CA2537326A1/en not_active Abandoned
- 2004-10-01 US US10/570,123 patent/US20070264251A1/en not_active Abandoned
- 2004-10-01 AU AU2004278556A patent/AU2004278556A1/en not_active Abandoned
- 2004-10-01 JP JP2006530584A patent/JP2007509606A/ja not_active Abandoned
-
2006
- 2006-03-13 IL IL174295A patent/IL174295A0/en unknown
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