JP2007506796A - Ｈｒｔ製剤 - Google Patents
Ｈｒｔ製剤 Download PDFInfo
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- JP2007506796A JP2007506796A JP2006529642A JP2006529642A JP2007506796A JP 2007506796 A JP2007506796 A JP 2007506796A JP 2006529642 A JP2006529642 A JP 2006529642A JP 2006529642 A JP2006529642 A JP 2006529642A JP 2007506796 A JP2007506796 A JP 2007506796A
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Classifications
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- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
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- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
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- A61K9/2022—Organic macromolecular compounds
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- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
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- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A—HUMAN NECESSITIES
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- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/34—Gestagens
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
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- Reproductive Health (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Gynecology & Obstetrics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
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| DKPA200301828 | 2003-12-10 | ||
| US53612104P | 2004-01-13 | 2004-01-13 | |
| PCT/DK2004/000638 WO2005030175A1 (en) | 2003-09-29 | 2004-09-21 | Hrt formulations |
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| DE202007019049U1 (de) | 2007-11-05 | 2010-05-12 | Bayer Schering Pharma Aktiengesellschaft | Verwendung eines Gestagens in Kombination mit einem Estrogen zur Prophylaxe der Laktoseintoleranz bei der oralen Kontrazeption |
| EP2127643A1 (de) * | 2008-05-30 | 2009-12-02 | Bayer Schering Pharma Aktiengesellschaft | Orale Pelletformulierungen mit zeitversetzter Wirkstofffreigabe |
| EA026095B1 (ru) | 2010-04-15 | 2017-03-31 | Байер Интеллекчуал Проперти Гмбх | Очень низкодозированные твердые пероральные лекарственные формы для гормонозаместительной терапии (гзт) |
| EP2383279A1 (en) | 2011-07-19 | 2011-11-02 | Pantarhei Bioscience B.V. | Process for the preparation of estetrol |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| JP6285866B2 (ja) | 2011-11-23 | 2018-02-28 | セラピューティックスエムディー インコーポレーテッドＴｈｅｒａｐｅｕｔｉｃｓｍｄ， Ｉｎｃ． | 天然複合ホルモン補充製剤および療法 |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10413504B2 (en) * | 2013-12-11 | 2019-09-17 | Merck Sharp & Dohme Corp. | Intravaginal ring drug delivery system |
| US10206932B2 (en) | 2014-05-22 | 2019-02-19 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| WO2016203006A1 (en) | 2015-06-18 | 2016-12-22 | Mithra Pharmaceuticals S.A. | Orodispersible dosage unit containing an estetrol component |
| US10894014B2 (en) | 2015-06-18 | 2021-01-19 | Estetra Sprl | Orodispersible tablet containing Estetrol |
| LT3106148T (lt) | 2015-06-18 | 2018-06-25 | Mithra Pharmaceuticals S.A. | Burnoje disperguojamos dozės vienetas, turintis estetrolio komponentą |
| DK3310346T3 (da) | 2015-06-18 | 2021-05-25 | Estetra Sprl | Orodispersibel tablet indeholdende estetrol |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
| US9931349B2 (en) | 2016-04-01 | 2018-04-03 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
| KR102712911B1 (ko) | 2016-08-05 | 2024-10-04 | 에스테트라, 소시에떼 아 레스폰서빌리떼 리미떼 | 월경통 및 생리통의 관리방법 |
| TWI801561B (zh) | 2018-04-19 | 2023-05-11 | 比利時商依思特拉私人有限責任公司 | 化合物及其用於緩解絕經相關症狀的用途 |
| JOP20200260A1 (ar) | 2018-04-19 | 2019-10-19 | Estetra Sprl | مركبات واستخداماتها للتخفيف من الأعراض المصاحبة لانقطاع الطمث |
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| JPS60100520A (ja) * | 1983-08-05 | 1985-06-04 | プリ ジエイ ホールディングス リミテッド | 周閉経期、閉経期および閉経期後の障害をホルモン的に治療する医薬品組成物 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US4390531A (en) * | 1981-08-10 | 1983-06-28 | Syntex Pharmaceuticals International Ltd. | Method of contraception using peak progestogen dosage |
| US4826831A (en) * | 1983-08-05 | 1989-05-02 | Pre Jay Holdings Limited | Method of hormonal treatment for menopausal or post-menopausal disorders involving continuous administration of progestogens and estrogens |
| US4530839A (en) * | 1983-09-26 | 1985-07-23 | Ortho Pharmaceutical Corporation | Triphasic oral contraceptive |
| US5208225A (en) * | 1986-02-27 | 1993-05-04 | Warner-Lambert Company | Compositions containing fixed combinations |
| US4946686A (en) * | 1987-09-24 | 1990-08-07 | Merck & Co., Inc. | Solubility modulated drug delivery system |
| US5200197A (en) * | 1989-11-16 | 1993-04-06 | Alza Corporation | Contraceptive pill |
| US5633011A (en) * | 1994-08-04 | 1997-05-27 | Alza Corporation | Progesterone replacement therapy |
| DE69530308T2 (de) * | 1994-09-22 | 2003-10-16 | Akzo Nobel N.V., Arnheim/Arnhem | Verfahren zur herstellung von dosierungsformen durch feuchtgranulierung |
| US20010006963A1 (en) | 1995-03-16 | 2001-07-05 | Ursula Lachnit-Fixson | Once-a-month injection as a depot contraceptive and for hormone replacement therapy for perimenopausal and premenopausal women |
| US5780050A (en) * | 1995-07-20 | 1998-07-14 | Theratech, Inc. | Drug delivery compositions for improved stability of steroids |
| US5897880A (en) * | 1995-09-29 | 1999-04-27 | Lam Pharmaceuticals, Llc. | Topical drug preparations |
| US5928666A (en) * | 1996-11-12 | 1999-07-27 | Cygnus Inc. | Crystalline form of estradiol and pharmaceutical formulations comprising same |
| IL128818A0 (en) * | 1998-03-12 | 2000-01-31 | Akzo Nobel Nv | Making dosage units using low shear granulation |
| US6117446A (en) * | 1999-01-26 | 2000-09-12 | Place; Virgil A. | Drug dosage unit for buccal administration of steroidal active agents |
| US7374779B2 (en) * | 1999-02-26 | 2008-05-20 | Lipocine, Inc. | Pharmaceutical formulations and systems for improved absorption and multistage release of active agents |
| CA2267743C (en) * | 1999-03-30 | 2011-07-26 | Robert F. Casper | Low dose estrogen interrupted hormone replacement therapy |
| US6667050B1 (en) * | 1999-04-06 | 2003-12-23 | Galen (Chemicals) Limited | Chewable oral contraceptive |
| DE10100911A1 (de) | 2001-01-11 | 2002-08-01 | Schering Ag | Verfahren zur Hormonersatztherapie und dessen Darreichungsform |
| US6962908B2 (en) * | 2001-12-21 | 2005-11-08 | Warner Chilcott Company Inc. | Oral pharmaceutical products containing 17 β-estradiol-3-lower alkanoate, method of administering the same and process of preparation |
| TW200306846A (en) * | 2002-04-03 | 2003-12-01 | Wyeth Corp | Hormone replacement therapy |
| TW200400040A (en) * | 2002-05-17 | 2004-01-01 | Wyeth Corp | Hormone replacement therapy |
| US20040185093A1 (en) * | 2003-03-18 | 2004-09-23 | Szymczak Christopher E. | Compositions containing sucralose |
| US20040265373A1 (en) * | 2003-06-27 | 2004-12-30 | David Wynn | Soft tablet containing high molecular weight cellulosics |
-
2004
- 2004-09-21 PT PT47628581T patent/PT1670440E/pt unknown
- 2004-09-21 DK DK04762858.1T patent/DK1670440T3/da active
- 2004-09-21 ES ES04762858.1T patent/ES2482104T3/es not_active Expired - Lifetime
- 2004-09-21 WO PCT/DK2004/000638 patent/WO2005030175A1/en active Application Filing
- 2004-09-21 EP EP10178130A patent/EP2295041A3/en not_active Withdrawn
- 2004-09-21 PL PL04762858T patent/PL1670440T3/pl unknown
- 2004-09-21 JP JP2006529642A patent/JP2007506796A/ja active Pending
- 2004-09-21 AU AU2004275469A patent/AU2004275469B2/en not_active Ceased
- 2004-09-21 EP EP04762858.1A patent/EP1670440B1/en not_active Revoked
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2006
- 2006-03-17 US US11/378,976 patent/US20060281721A1/en not_active Abandoned
- 2006-05-23 IL IL175843A patent/IL175843A0/en unknown
-
2012
- 2012-01-13 JP JP2012004614A patent/JP2012126725A/ja not_active Withdrawn
-
2015
- 2015-01-08 JP JP2015002288A patent/JP2015110604A/ja not_active Withdrawn
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60100520A (ja) * | 1983-08-05 | 1985-06-04 | プリ ジエイ ホールディングス リミテッド | 周閉経期、閉経期および閉経期後の障害をホルモン的に治療する医薬品組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| DK1670440T3 (da) | 2014-07-07 |
| AU2004275469B2 (en) | 2010-07-15 |
| US20060281721A1 (en) | 2006-12-14 |
| WO2005030175A1 (en) | 2005-04-07 |
| EP1670440A1 (en) | 2006-06-21 |
| AU2004275469A1 (en) | 2005-04-07 |
| PL1670440T3 (pl) | 2014-11-28 |
| ES2482104T3 (es) | 2014-08-01 |
| PT1670440E (pt) | 2014-08-22 |
| JP2012126725A (ja) | 2012-07-05 |
| JP2015110604A (ja) | 2015-06-18 |
| EP2295041A2 (en) | 2011-03-16 |
| IL175843A0 (en) | 2006-10-05 |
| EP2295041A3 (en) | 2012-01-04 |
| EP1670440B1 (en) | 2014-04-30 |
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