JP2007505883A5 - - Google Patents

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Publication number
JP2007505883A5
JP2007505883A5 JP2006526715A JP2006526715A JP2007505883A5 JP 2007505883 A5 JP2007505883 A5 JP 2007505883A5 JP 2006526715 A JP2006526715 A JP 2006526715A JP 2006526715 A JP2006526715 A JP 2006526715A JP 2007505883 A5 JP2007505883 A5 JP 2007505883A5
Authority
JP
Japan
Prior art keywords
parathyroid hormone
composition
osteoporosis
treating
composition according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2006526715A
Other languages
English (en)
Other versions
JP2007505883A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2004/002902 external-priority patent/WO2005027915A1/en
Publication of JP2007505883A publication Critical patent/JP2007505883A/ja
Publication of JP2007505883A5 publication Critical patent/JP2007505883A5/ja
Pending legal-status Critical Current

Links

Claims (6)

  1. 化合物:2−メチレン−19−ノル−20(S)−1α,25−ジヒドロキシビタミンDと副甲状腺ホルモン又はその活性断片又は変異体を含む医薬組成物。
  2. 副甲状腺ホルモンがヒト組換え副甲状腺ホルモンである、請求項1の組成物。
  3. 副甲状腺ホルモンがヒト組換え副甲状腺ホルモン1−34である、請求項1の組成物。
  4. 老年性骨粗鬆症、閉経後骨粗鬆症、骨折、移植骨片、乳癌、前立腺癌、肥満、骨減少症、男性骨粗鬆症、虚弱、筋損傷、又は肉減少症を治療するための、請求項1〜3のいずれか1項に記載の組成物。
  5. 閉経後骨粗鬆症を治療するための、請求項1〜3のいずれか1項に記載の組成物。
  6. 骨折を治療するための、請求項1〜3のいずれか1項に記載の組成物。
JP2006526715A 2003-09-19 2004-09-06 2−アルキリデン−19−ノル−ビタミンd誘導体及び副甲状腺ホルモンの組合せを含んでなる医薬組成物及び方法 Pending JP2007505883A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50450303P 2003-09-19 2003-09-19
PCT/IB2004/002902 WO2005027915A1 (en) 2003-09-19 2004-09-06 Pharmaceutical compositions and methods comprising combinations of 2-alkylidene-19-nor-vitamin d derivatives and parathyroid hormone

Publications (2)

Publication Number Publication Date
JP2007505883A JP2007505883A (ja) 2007-03-15
JP2007505883A5 true JP2007505883A5 (ja) 2007-11-08

Family

ID=34375509

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006526715A Pending JP2007505883A (ja) 2003-09-19 2004-09-06 2−アルキリデン−19−ノル−ビタミンd誘導体及び副甲状腺ホルモンの組合せを含んでなる医薬組成物及び方法

Country Status (15)

Country Link
US (1) US20050065088A1 (ja)
EP (1) EP1667689A1 (ja)
JP (1) JP2007505883A (ja)
KR (1) KR20060058133A (ja)
CN (1) CN1852716A (ja)
AU (1) AU2004273660B2 (ja)
BR (1) BRPI0414518A (ja)
CA (1) CA2539357A1 (ja)
IL (1) IL174144A0 (ja)
MX (1) MXPA06003064A (ja)
NO (1) NO20061236L (ja)
NZ (1) NZ545803A (ja)
RU (1) RU2006108557A (ja)
TW (1) TW200511999A (ja)
WO (1) WO2005027915A1 (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7122533B2 (en) * 1999-11-29 2006-10-17 The United States Of America As Represented By The Department Of Health And Human Services Cosalane compounds and methods for their use
JP2007512371A (ja) * 2003-11-25 2007-05-17 デルタノイド ファーマシューティカルズ,インコーポレイティド ビタミン化合物を用いる体脂肪の減少方法
WO2005051323A2 (en) 2003-11-25 2005-06-09 Wisconsin Alumni Research Foundation Vitamin d analogs for obesity prevention and treatment
AU2006213722B2 (en) * 2005-02-11 2011-09-22 Wisconsin Alumni Research Foundation 2-methylene-19-nor-(20S-24epi)-1alpha,25-dihydroxyvitamin-D2
EP1853274B1 (en) * 2005-02-11 2013-01-23 Wisconsin Alumni Research Foundation 2-methylene-19-nor- (20s-24s) - 1alpha, 25-dihydroxyvitamine-d2
US7235680B2 (en) * 2005-03-29 2007-06-26 Wisconsin Alumni Research Foundation 2-methylene-19-nor-(23S)-25-dehydro-1α-hydroxyvitamin D3-26,23-lactone and 2-methylene-19-nor-(23R)-25-dehydro-1α-hydroxyvitamin D3-26,23-lactone
EP2556054B1 (en) * 2010-03-23 2017-09-27 Wisconsin Alumni Research Foundation Diastereomers of 2-methylene-19-nor-22-methyl-1alpha,25-dihydroxyvitamin d3
AU2011232633B2 (en) 2010-03-23 2014-05-29 Wisconsin Alumni Research Foundation (20S)-2-methylene-19-nor-22-dimethyl-1alpha,25- dihydroxyvitamin D3 and (20R)-2-methylene-19-nor-22- dimethyl-1alpha,25-hydroxyvitamin D3
US8664206B2 (en) 2010-03-23 2014-03-04 Wisconsin Alumni Research Foundation Diastereomers of 2-methylene-19-nor-22-methyl-1α,25-dihydroxyvitamin D3
WO2015050160A1 (ja) * 2013-10-03 2015-04-09 国立大学法人大阪大学 副甲状腺ホルモンまたはその誘導体を有効成分とする筋の老化防止用医薬組成物
JP6566520B2 (ja) * 2013-10-29 2019-08-28 国立大学法人 熊本大学 筋疾患の治療または予防のための医薬組成物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL78342A (en) * 1985-04-04 1991-06-10 Gen Hospital Corp Pharmaceutical composition for treatment of osteoporosis in humans comprising a parathyroid hormone or a fragment thereof
US5086191A (en) * 1991-05-28 1992-02-04 Wisconsin Alumni Research Foundation Intermediates for the synthesis of 19-nor vitamin D compounds
EP0619306B1 (en) * 1993-04-05 1996-09-11 Wisconsin Alumni Research Foundation 19-Nor-vitamin D3 compounds with substituent at 2-position
US5843928A (en) * 1997-03-17 1998-12-01 Wisconsin Alumni Research Foundation 2-alkylidene-19-nor-vitamin D compounds
DZ2873A1 (fr) * 1998-08-19 2003-12-15 Lilly Co Eli Procédé pour augmenter la dureté et la rigidité osseuse.
EP1136076A1 (en) * 1998-08-19 2001-09-26 Eli Lilly And Company Method of increasing bone toughness and stiffness and reducing fractures

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