JP2007505163A - Sars感染の画像解析可能な動物モデル - Google Patents

Sars感染の画像解析可能な動物モデル Download PDF

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Publication number
JP2007505163A
JP2007505163A JP2006533504A JP2006533504A JP2007505163A JP 2007505163 A JP2007505163 A JP 2007505163A JP 2006533504 A JP2006533504 A JP 2006533504A JP 2006533504 A JP2006533504 A JP 2006533504A JP 2007505163 A JP2007505163 A JP 2007505163A
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Prior art keywords
protein
group
coronavirus
animal model
fluorescence
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JP2006533504A
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English (en)
Japanese (ja)
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JP2007505163A5 (https=
Inventor
ヤン,メン
シュ,ミンシュ
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アンチキャンサー インコーポレーテッド
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Publication of JP2007505163A publication Critical patent/JP2007505163A/ja
Publication of JP2007505163A5 publication Critical patent/JP2007505163A5/ja
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082Supracellular entities, e.g. tissue, organisms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • A01K2227/105Murine
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/03Animal model, e.g. for test or diseases
    • A01K2267/0337Animal models for infectious diseases
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/03Animal model, e.g. for test or diseases
    • A01K2267/0393Animal model comprising a reporter system for screening tests
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/60Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/20011Coronaviridae
    • C12N2770/20022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08RNA viruses
    • G01N2333/165Coronaviridae, e.g. avian infectious bronchitis virus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Physiology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2006533504A 2003-05-27 2004-05-27 Sars感染の画像解析可能な動物モデル Pending JP2007505163A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47369103P 2003-05-27 2003-05-27
PCT/US2004/016976 WO2004106497A2 (en) 2003-05-27 2004-05-27 Imageable animal model of sars infection

Publications (2)

Publication Number Publication Date
JP2007505163A true JP2007505163A (ja) 2007-03-08
JP2007505163A5 JP2007505163A5 (https=) 2007-08-09

Family

ID=33490633

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006533504A Pending JP2007505163A (ja) 2003-05-27 2004-05-27 Sars感染の画像解析可能な動物モデル

Country Status (7)

Country Link
US (1) US20050039220A1 (https=)
EP (1) EP1628996A4 (https=)
JP (1) JP2007505163A (https=)
CN (1) CN1829732A (https=)
AU (1) AU2004243886A1 (https=)
CA (1) CA2527296A1 (https=)
WO (1) WO2004106497A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023523828A (ja) * 2020-04-30 2023-06-07 ヤン シェン ターン カンパニー リミテッド コロナウイルス感染の遮断薬をスクリーニングする検出試薬及び検出方法

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102669017B (zh) * 2011-12-19 2015-02-25 河南科技大学 一种体内细菌生物被膜感染动物模型的构建方法
WO2021147025A1 (en) * 2020-01-22 2021-07-29 The University Of Hong Kong-Shenzhen Hospital Anti 2019-ncov vaccine
CN114360646A (zh) * 2020-04-03 2022-04-15 郑鑫 类似sars冠状病毒溯源和评估致病力的方法及装置

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001071009A2 (en) * 2000-03-17 2001-09-27 Anticancer, Inc. Whole-body optical imaging of gene expression and uses thereof
WO2002092827A2 (en) * 2001-05-17 2002-11-21 Universiteit Utrecht Corona-virus-like particles comprising functionally deleted genomes
WO2003006069A1 (en) * 2001-07-09 2003-01-23 Anticancer, Inc. Imaging infection using fluorescent protein as a marker

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6251384B1 (en) * 1997-04-28 2001-06-26 Anticancer, Inc. Metastasis models using green fluorescent protein (GFP) as a marker
US6232523B1 (en) * 1997-04-28 2001-05-15 Anticancer, Inc. Metastasis models using green fluorescent protein (GFP) as a marker
AU749338B2 (en) * 1997-04-28 2002-06-27 Anticancer, Inc. Metastasis models using green fluorescent protein (GFP) as a marker

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001071009A2 (en) * 2000-03-17 2001-09-27 Anticancer, Inc. Whole-body optical imaging of gene expression and uses thereof
WO2002092827A2 (en) * 2001-05-17 2002-11-21 Universiteit Utrecht Corona-virus-like particles comprising functionally deleted genomes
WO2003006069A1 (en) * 2001-07-09 2003-01-23 Anticancer, Inc. Imaging infection using fluorescent protein as a marker

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023523828A (ja) * 2020-04-30 2023-06-07 ヤン シェン ターン カンパニー リミテッド コロナウイルス感染の遮断薬をスクリーニングする検出試薬及び検出方法

Also Published As

Publication number Publication date
US20050039220A1 (en) 2005-02-17
WO2004106497A3 (en) 2005-05-12
CA2527296A1 (en) 2004-12-09
EP1628996A4 (en) 2008-01-09
EP1628996A2 (en) 2006-03-01
CN1829732A (zh) 2006-09-06
WO2004106497A2 (en) 2004-12-09
AU2004243886A1 (en) 2004-12-09

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