JP2007326831A - Buccal stain-removing agent - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a buccal stain-removing agent which can be suitably used for readily removing buccal stain only by washing a mouth therewith without a brush, has an excellent performance to remove stain, and can be produced as a uniform composition. <P>SOLUTION: The buccal stain-removing agent comprises a polyoxyethylene alkyl ether having a 12-18C alkyl group. <P>COPYRIGHT: (C)2008,JPO&INPIT

Description

  The present invention relates to an oral decontamination agent having excellent decontamination power in the oral cavity, particularly on the tooth surface.

  Conventionally, dentifrices, mouthwashes, and the like have been used to remove dirt (oral dirt) such as food residues adhering to the oral cavity and tooth surface and discomfort in the oral cavity. Since the dentifrice removes oral dirt mechanically by the action of the abrasive contained therein, the effect of removing dirt cannot be expected unless a brush is used.

On the other hand, a mouthwash is used after being rinsed in the oral cavity, and since it is not necessary to use a brush, it is simple but the cleaning power is not sufficient. Therefore, means for improving the cleaning power in the oral cavity has been studied. For example, as described in Patent Document 1, N ^ε -long-chain acyl lysine is used as an oral decontamination agent, and as described in Patent Document 2, purified starch is hydrolyzed and hydrogenated. The thing containing the reduced starch decomposition product obtained by refinement | purification etc. is known.

  However, in the thing of patent document 1, only the dirt removal ability in liquid toothpaste is evaluated by (circle) and x. Moreover, although the thing of patent document 2 shows evaluation of the cleaning power by a mouthwash using a model system, it cannot be said that the stain removal rate is about 60 to 70% and the cleaning power is sufficient.

JP 2001-58933 A ([0020] to [0021]) JP 2000-95656 A ([0004], [0012] to [0015])

  Therefore, the present invention can easily remove oral dirt just by rinsing in the oral cavity without using a brush. It provides a decontamination agent.

  As a result of intensive studies to solve the above-mentioned problems, the present inventors have found that polyoxyethylene alkyl ethers, which are one type of surfactant, have a specific alkyl group, which is an oral stain, particularly a tooth surface. The present inventors have found that it is very excellent in the action of removing dirt and has reached the present invention.

That is, the present invention is achieved by the following (1) oral dirt remover.
(1) An oral dirt remover comprising a polyoxyethylene alkyl ether having an alkyl group having 12 to 18 carbon atoms.

  By using the oral dirt removing agent of the present invention, it is possible to easily and effectively remove the dirt in the oral cavity, particularly the dirt on the tooth surface. And, by using the oral dirt remover of the present invention blended into a liquid oral composition such as mouthwash, the ability to remove dirt in the oral cavity can be dramatically increased, and there is no white turbidity or separation. Can be made into a composition.

  The oral dirt remover of the present invention comprises a polyoxyethylene alkyl ether having an alkyl group having 12 to 18 carbon atoms (hereinafter, “polyoxyethylene” is also referred to as “POE”) as an active ingredient. , POE (20) stearyl ether, POE (21) lauryl ether, POE (25) cetyl ether, POE (40) cetyl ether, POE (20) oleyl ether, POE (50) oleyl ether, and the like.

  The oral decontamination remover of the present invention can be used alone for removing dirt and cleaning of the oral cavity and tooth surface, but may be used in a liquid oral composition such as mouthwash. When blending the oral dirt remover of the present invention in a liquid oral composition, the POE alkyl ether is blended in an amount of 0.05 to 10% by weight, preferably 0.1 to 3% by weight, based on the total composition. It is good. In the liquid oral composition, if the amount of the POE alkyl ether is too small, a sufficient ability to remove dirt cannot be obtained, and if it is too large, bitterness and excessive foaming are not preferable.

  In addition to the above components, the liquid oral composition can be prepared using various components used in this field. Examples of the component include solvents such as water and ethanol; fluorides such as sodium fluoride and sodium monofluorophosphate; azulene, azulene sulfonate, β-glycyrrhetinic acid, glycyrrhizic acid and salts, dihydrocholesterol, epidihydrocholester Anti-inflammatory agents such as phosphorus, agaric extract, sugar beet extract, dl-α-tocopherol acetate, ε-aminocaproic acid, tranexamic acid; cetylpyridinium chloride, benzalkonium chloride, benzethonium chloride, chlorhexidine salts, triclosan, isopropylmethylphenol, alkyldiamino hydrochloride Bactericides such as ethylglycine; anticalculus agents such as polyphosphate, pyrophosphate, gantrezic acid, zinc chloride, organic acid zinc; hinokitiol, allantoin, allantochlorohydroxyaluminum Alum, allantoindihydroxyaluminum, sodium chloride, etc .; humectants such as glycerin, sorbitol, polyethylene glycol; foaming agents such as sodium lauryl sulfate; peppermint oil, peppermint oil, anise oil, cinnamon oil, glove oil, eugenol, lemon Fragrances such as oil, vanillin, cineole, eucalyptus oil, α-pinene; sweeteners such as saccharin, sodium saccharin, xylitol, erystol, sorbitol, stevia, dipotassium glycyrrhizinate; blue No. 1, yellow No. 4, yellow 202 (1 ), Green 3, yellow 201, red 102, etc .; parabens, preservatives such as sodium benzoate; monosodium dihydrogen phosphate, disodium monohydrogen phosphate, citric acid, fruit acid, etc. Of buffering agents The

  In addition to the above components, examples include aluminum lactate, potassium nitrate, shellac, beeswax, hydroxyapatite, copper chlorophyllin sodium, vitamins, calcium phosphates, chelating agents, essential oil components, plant extracts, and aromatic components.

  Since the POE alkyl ether which is an oral dirt removing agent of the present invention is also a kind of surfactant, the above-mentioned various components can be dissolved, dispersed and solubilized in a solvent. It is not necessary to use an agent, but when using a poorly soluble component, another surfactant can be used in combination as required. Examples of such other surfactants include glycerin fatty acid ester, sorbitan fatty acid ester, sucrose fatty acid ester, polyoxyethylene alkylphenyl ether, polyoxyethylene polyoxypropylene glycol, polyethylene glycol fatty acid ester, and polyoxyethylene sorbitan fatty acid ester. And polyoxyethylene hydrogenated castor oil.

  EXAMPLES The present invention will be described in more detail with reference to examples below, but the present invention is not limited to these examples.

Test preparations listed in Table 1 were prepared, and the dirt removal ability was evaluated by a model system using a test plate.
<Preparation of test plate>
An oral food residue consisting of fats and oils was prepared as human oral dirt. Specifically, 12g of salad oil and 8g of lard (pig fat) are placed in a heated container, heated to about 100 ° C and mixed, and then heated and mixed well to prevent lumps by adding 20g of flour. A food residue. This residue is put in a beaker and kept at 70 ° C. A glass slide (assuming the tooth surface) is immersed in it for 1 to 2 seconds, and excess residue is sucked off by Kimwipe and dried at 25 ° C. for 2 hours. Was used as a test plate in the dirt removal test.

<Decontamination test>
30 ml of the test preparation was placed in a 50 ml sample tube and kept at 37 ° C. A test plate was put there and covered, and the sample tube was tumbled so that the test plate was parallel, and shaken at a rate of 120 times / minute for 30 seconds, assuming mouthwash in the oral cavity. Thereafter, the test plate was taken out of the sample tube, excess moisture was absorbed with a Kimwipe, and the weight was measured after drying at 25 ° C. for 1 hour. And from the difference with the weight of the test plate measured before the test, the dirt removal rate (%) was calculated and evaluated by the following formula.

[formula]
Dirt removal rate (%) = (1−Test plate weight before test ÷ Test plate weight after test) × 100

<result>
The test results are shown in Table 1. Test preparations 1 to 6 using POE alkyl ether having an alkyl group having 12 to 18 carbon atoms had a very high dirt removal rate of about 80% or more. An excellent removal power was not obtained in the test preparation 7 using POE behenyl ether having an alkyl group having 22 carbon atoms. Therefore, the high decontamination effect by the test preparations 1 to 6 is an effect that is specifically recognized by having an alkyl group having a specific carbon number, and is particularly excellent in the decontamination effect on food residues due to fats and oils and starch. It is considered a thing. In addition, in all of these other components, the decontamination rate was low and comparable to that of purified water.

  From this result, a POE alkyl ether having an alkyl group having 12 to 18 carbon atoms is used for a liquid oral composition, whereby an excellent removal effect against oral dirt can be obtained.

The formulation example using the oral decontamination agent of this invention is shown.
Formulation Example 1
Component Content (mass%)
Ethanol 10
Glycerin 15
POE (20) stearyl ether 0.4
Methylparaben 0.05
Sodium monohydrogen phosphate Appropriate amount Sodium dihydrogen phosphate Appropriate amount Cetylpyridinium chloride 0.02
Xylitol 3.0
Fragrance 0.1
Dye Trace amount of purified water Total remaining 100

Formulation Example 2
Component Content (mass%)
Ethanol 10
Glycerin 15
POE (21) lauryl ether 0.4
Butylparaben 0.03
Sodium monohydrogen phosphate Appropriate amount Sodium dihydrogen phosphate Appropriate amount Tranexamic acid 0.01
Xylitol 5.0
Fragrance 0.1
Dye Trace amount of purified water Total remaining 100

Formulation Example 3
Component Content (mass%)
Ethanol 10
Glycerin 15
POE (25) cetyl ether 0.5
Propylparaben 0.1
Sodium monohydrogen phosphate Appropriate amount Sodium dihydrogen phosphate Appropriate amount Benzethonium chloride 0.01
Xylitol 3.0
Fragrance 0.1
Dye Trace amount of purified water Total remaining 100

Formulation Example 4
Component Content (mass%)
Ethanol 15
Glycerin 15
POE (20) stearyl ether 0.3
Sodium hydroxide 0.02
Shellac 0.5
Cetylpyridinium chloride 0.02
Sodium bicarbonate 0.1
Xylitol 2.0
Fragrance 0.1
Dye Trace amount of purified water Total remaining 100

Formulation Example 5
Component Content (mass%)
Ethanol 15
Glycerin 15
POE (20) oleyl ether 0.3
Butylparaben 0.05
Sodium monohydrogen phosphate Appropriate amount Sodium dihydrogen phosphate Appropriate amount Triclosan 0.02
Xylitol 0.5
Fragrance 0.1
Dye Trace amount of purified water Total remaining 100

Claims (1)

  An oral dirt remover comprising a polyoxyethylene alkyl ether having an alkyl group having 12 to 18 carbon atoms.