JP2007314517A5 - - Google Patents
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- Publication number
- JP2007314517A5 JP2007314517A5 JP2007108055A JP2007108055A JP2007314517A5 JP 2007314517 A5 JP2007314517 A5 JP 2007314517A5 JP 2007108055 A JP2007108055 A JP 2007108055A JP 2007108055 A JP2007108055 A JP 2007108055A JP 2007314517 A5 JP2007314517 A5 JP 2007314517A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- caffeine
- ephedrine
- loxoprofen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- RYYVLZVUVIJVGH-UHFFFAOYSA-N caffeine Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 claims 15
- 239000008194 pharmaceutical composition Substances 0.000 claims 15
- OROGSEYTTFOCAN-DNJOTXNNSA-N Codeine Chemical compound C([C@H]1[C@H](N(CC[C@@]112)C)C3)=C[C@H](O)[C@@H]1OC1=C2C3=CC=C1OC OROGSEYTTFOCAN-DNJOTXNNSA-N 0.000 claims 12
- KWGRBVOPPLSCSI-WPRPVWTQSA-N Ephedrine Chemical compound CN[C@@H](C)[C@H](O)C1=CC=CC=C1 KWGRBVOPPLSCSI-WPRPVWTQSA-N 0.000 claims 12
- 229960001948 caffeine Drugs 0.000 claims 8
- YMBXTVYHTMGZDW-UHFFFAOYSA-N Loxoprofen Chemical compound C1=CC(C(C(O)=O)C)=CC=C1CC1C(=O)CCC1 YMBXTVYHTMGZDW-UHFFFAOYSA-N 0.000 claims 7
- 229960002373 loxoprofen Drugs 0.000 claims 7
- 229960002179 ephedrine Drugs 0.000 claims 6
- 229960004126 codeine Drugs 0.000 claims 5
- 206010006451 Bronchitis Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- DKSZLDSPXIWGFO-BLOJGBSASA-N (4R,4aR,7S,7aR,12bS)-9-methoxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-ol;phosphoric acid;hydrate Chemical compound O.OP(O)(O)=O.OP(O)(O)=O.C([C@H]1[C@H](N(CC[C@@]112)C)C3)=C[C@H](O)[C@@H]1OC1=C2C3=CC=C1OC.C([C@H]1[C@H](N(CC[C@@]112)C)C3)=C[C@H](O)[C@@H]1OC1=C2C3=CC=C1OC DKSZLDSPXIWGFO-BLOJGBSASA-N 0.000 claims 1
- 208000006673 Asthma Diseases 0.000 claims 1
- 206010006458 Bronchitis chronic Diseases 0.000 claims 1
- 208000007451 Chronic Bronchitis Diseases 0.000 claims 1
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 claims 1
- 229960004415 Codeine Phosphate Drugs 0.000 claims 1
- RBOXVHNMENFORY-DNJOTXNNSA-N Dihydrocodeine Chemical compound C([C@H]1[C@H](N(CC[C@@]112)C)C3)C[C@H](O)[C@@H]1OC1=C2C3=CC=C1OC RBOXVHNMENFORY-DNJOTXNNSA-N 0.000 claims 1
- 206010014561 Emphysema Diseases 0.000 claims 1
- 229960002534 Ephedrine hydrochloride Drugs 0.000 claims 1
- 210000002175 Goblet Cells Anatomy 0.000 claims 1
- 206010020718 Hyperplasia Diseases 0.000 claims 1
- 229940051020 Methylephedrine hydrochloride Drugs 0.000 claims 1
- 206010035653 Pneumoconiosis Diseases 0.000 claims 1
- 208000008128 Pulmonary Tuberculosis Diseases 0.000 claims 1
- 206010057190 Respiratory tract infection Diseases 0.000 claims 1
- NTCYWJCEOILKNG-ROLPUNSJSA-N [(1R,2S)-1-hydroxy-1-phenylpropan-2-yl]-dimethylazanium;chloride Chemical compound Cl.CN(C)[C@@H](C)[C@H](O)C1=CC=CC=C1 NTCYWJCEOILKNG-ROLPUNSJSA-N 0.000 claims 1
- 230000001154 acute Effects 0.000 claims 1
- 230000000954 anitussive Effects 0.000 claims 1
- 201000009267 bronchiectasis Diseases 0.000 claims 1
- 230000001684 chronic Effects 0.000 claims 1
- 229940000425 combination drugs Drugs 0.000 claims 1
- 229960000920 dihydrocodeine Drugs 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 230000003419 expectorant Effects 0.000 claims 1
- 239000003172 expectorant agent Substances 0.000 claims 1
- BALXUFOVQVENIU-UHFFFAOYSA-N hydron;2-(methylamino)-1-phenylpropan-1-ol;chloride Chemical group Cl.CNC(C)C(O)C1=CC=CC=C1 BALXUFOVQVENIU-UHFFFAOYSA-N 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 210000002345 respiratory system Anatomy 0.000 claims 1
- 230000001629 suppression Effects 0.000 claims 1
Claims (13)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007108055A JP2007314517A (en) | 2006-04-27 | 2007-04-17 | Antitussive or expectorant pharmaceutical composition comprising loxoprofen |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006124024 | 2006-04-27 | ||
| JP2007108055A JP2007314517A (en) | 2006-04-27 | 2007-04-17 | Antitussive or expectorant pharmaceutical composition comprising loxoprofen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007314517A JP2007314517A (en) | 2007-12-06 |
| JP2007314517A5 true JP2007314517A5 (en) | 2010-05-13 |
Family
ID=38848713
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007108055A Pending JP2007314517A (en) | 2006-04-27 | 2007-04-17 | Antitussive or expectorant pharmaceutical composition comprising loxoprofen |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2007314517A (en) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5835865B2 (en) * | 2008-09-04 | 2015-12-24 | 興和株式会社 | Loxoprofen-containing pharmaceutical composition |
| JP2010111667A (en) * | 2008-10-10 | 2010-05-20 | Daiichi Sankyo Healthcare Co Ltd | Medicinal composition for antitussive action and/or expectoration containing fexofenadine or ebastine |
| JP5739626B2 (en) * | 2009-07-27 | 2015-06-24 | 興和株式会社 | Pharmaceutical formulation |
| JP2011116750A (en) * | 2009-10-30 | 2011-06-16 | Kowa Co | Loxoprofen-containing pharmaceutical composition |
| JP5798734B2 (en) * | 2009-10-30 | 2015-10-21 | 興和株式会社 | Loxoprofen-containing pharmaceutical composition |
| JP2011225514A (en) * | 2009-10-30 | 2011-11-10 | Kowa Co | Pharmaceutical composition containing loxoprofen or salt thereof |
| JP5815226B2 (en) * | 2009-11-30 | 2015-11-17 | 興和株式会社 | Pharmaceutical composition containing loxoprofen |
| JP5897804B2 (en) * | 2010-02-26 | 2016-03-30 | 興和株式会社 | Loxoprofen-containing pharmaceutical composition |
| JP5798800B2 (en) * | 2010-05-28 | 2015-10-21 | 興和株式会社 | Loxoprofen-containing pharmaceutical preparation |
| JP2012106977A (en) * | 2010-05-31 | 2012-06-07 | Kowa Co | Pharmaceutical composition containing loxoprofen |
| JP6139050B2 (en) * | 2010-08-27 | 2017-05-31 | 興和株式会社 | Medicine |
| JP6112765B2 (en) * | 2010-12-13 | 2017-04-12 | 第一三共ヘルスケア株式会社 | Solid preparation containing loxoprofen sodium and dl-methylephedrine hydrochloride |
| JP5898963B2 (en) * | 2011-01-12 | 2016-04-06 | 興和株式会社 | Pharmaceutical composition containing loxoprofen or a salt thereof |
| JP6008857B2 (en) * | 2011-07-29 | 2016-10-19 | 興和株式会社 | Pharmaceutical composition containing loxoprofen |
| JP6157214B2 (en) * | 2012-05-25 | 2017-07-05 | 第一三共ヘルスケア株式会社 | Antipyretic analgesic composition |
| JP6226597B2 (en) * | 2012-07-13 | 2017-11-08 | 第一三共ヘルスケア株式会社 | Antipyretic analgesic composition |
| JP2016135745A (en) * | 2014-01-20 | 2016-07-28 | 興和株式会社 | Loxoprofen-containing expectorant pharmaceutical composition |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4357016B2 (en) * | 1998-11-06 | 2009-11-04 | 第一三共株式会社 | Pharmaceutical composition containing loxoprofen |
| JP2001172175A (en) * | 1999-12-14 | 2001-06-26 | Taisho Pharmaceut Co Ltd | Composition for the cold |
| JP2003095978A (en) * | 2001-09-27 | 2003-04-03 | Takeda Chem Ind Ltd | Antitussive and expectorant medicine composition |
-
2007
- 2007-04-17 JP JP2007108055A patent/JP2007314517A/en active Pending
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