JP2007215831A - Deodorant composition for stoma prosthesis and stoma prosthesis - Google Patents
Deodorant composition for stoma prosthesis and stoma prosthesis Download PDFInfo
- Publication number
- JP2007215831A JP2007215831A JP2006040841A JP2006040841A JP2007215831A JP 2007215831 A JP2007215831 A JP 2007215831A JP 2006040841 A JP2006040841 A JP 2006040841A JP 2006040841 A JP2006040841 A JP 2006040841A JP 2007215831 A JP2007215831 A JP 2007215831A
- Authority
- JP
- Japan
- Prior art keywords
- deodorant composition
- stoma
- deodorant
- weight
- powder
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Abstract
Description
本発明は、人体からの排泄物、排泄液、ガス、滲出液、分泌液等（本発明では、これらを総称して「排泄物等」という。）を処理するために使用される、即効性のあるストーマ装具用の消臭剤組成物及びこの消臭剤組成物を収納してなるストーマ装具に関する。 INDUSTRIAL APPLICABILITY The present invention is an immediate effect used for treating excrement, excretion fluid, gas, exudate, secretion fluid, etc. from the human body (in the present invention, these are collectively called “excretion etc.”). The present invention relates to a deodorant composition for an ostomy device having a stoma and a stoma device containing the deodorant composition.
消化器系又は泌尿器系器官の疾患がある場合や、便や尿の排泄を自らの意志により制御できない場合に、外科的手術を行い消化管や尿路を体表まで導き体表面にストーマを造設した人は、ストーマからの排泄物等を一時的に貯留できるストーマ装具をストーマの周囲に装着する。
通常、これらのストーマ装具は、排泄物等を収集する袋と袋を体表面に固定する面板とから構成され、袋は、防臭性の材料（例えばポリ塩化ビニリデン等）で外界に対し密封状態に形成される。従って、たとえ排泄物等が袋内に収容されているような状態にあっても臭気が漏れることはない。しかしながら、袋を再利用又は廃棄するために袋から排泄物等を取り出す際には、排泄物等から強い臭気が発生するので、このような排出操作に不快感をもつ装着者は少なくない。
また、おむつ、尿パッド、生理用ナプキン、医療用吸収パッド等の排泄物等処理用品においても、これら用品を装着している間は、排泄物等の臭いが漏れることはさほどないが、用品を適用部位から取り外した途端に臭気が拡散するという問題があった。
When there is a disease of the digestive system or urinary system or when excretion of stool or urine cannot be controlled by one's will, surgical operation is performed to bring the digestive tract and urinary tract to the body surface and create a stoma on the body surface. The person who installs wears a stoma appliance that can temporarily store the excrement etc. from the stoma around the stoma.
Normally, these stoma devices are composed of a bag for collecting excreta and the like and a face plate for fixing the bag to the body surface, and the bag is sealed against the outside with a deodorizing material (for example, polyvinylidene chloride). It is formed. Therefore, even if the excrement etc. are contained in the bag, the odor does not leak. However, when excrement etc. are taken out from the bag in order to reuse or dispose of the bag, a strong odor is generated from the excrement etc., so there are not a few wearers who are uncomfortable with such a discharge operation.
Also, in the excrement disposal products such as diapers, urine pads, sanitary napkins, medical absorbent pads, etc., while these products are worn, the smell of excrement etc. is not leaking so much. There was a problem that the odor diffused as soon as it was removed from the application site.
こうしたことから、排泄物等の臭気を除去するために、様々な消臭剤や消臭方法が提案されている。
特許文献１には、亜炭及びゼオライトを主成分とし、これにポリアクリルアミド系高分子化合物又はシリカゲルを添加して、これらを粉末形成してなる排泄物脱臭吸水剤が開示されている。
特許文献２には、有機化合物と粘土との混合物を真空中で加熱して炭化させて得られる多孔質の炭化物と多孔質のセラミックスとの複合物であるストーマ用消臭剤が開示されている。
これらの消臭剤は、悪臭成分との十分な接触時間がある場合には良好な消臭効果を発揮する。
ところが、ストーマ装具の状態や排泄物等の貯留の状況等によっては、装具の交換や排泄物等廃棄の間隔が短時間となる場合もある。
このような場合に従来のストーマ用消臭剤を使用しても、これらの消臭剤は即効性に劣っているので、ストーマ装具交換時には臭気が未だ残っており、上記臭気の問題を解決することができない。
従って、消臭の即効性に優れたストーマ装具用消臭剤が求められている。
また、排泄物等の処理に時間を要すると、臭気等による不快感を受けやすくなるので、排泄物等の短時間での処理を可能にするストーマ装具用消臭剤が求められている。
For these reasons, various deodorants and deodorization methods have been proposed in order to remove odors such as excreta.
These deodorizers exhibit a good deodorizing effect when there is sufficient contact time with malodorous components.
However, depending on the state of the stoma device, the state of storage of excrement, etc., the interval between exchanging the device and discarding excrement may be short.
In such cases, even if conventional stoma deodorants are used, these deodorants are inferior in immediate effect, so that the odor still remains when the stoma device is replaced, thus solving the above-mentioned odor problem. I can't.
Therefore, there is a need for a deodorant for stoma appliances that is excellent in the immediate effect of deodorization.
Moreover, since it will become easy to receive the discomfort by an odor etc. if processing of excrement etc. requires time, the deodorizer for stoma appliances which can process excrement etc. in a short time is calculated | required.
従って、本発明の目的は、ストーマ装具中の排泄物等の臭いに対して即効性があり、また、排泄物等の短時間での処理が可能になるストーマ装具用消臭剤組成物を提供することにある。
また、本発明の他の目的は、排泄物等を収容するための袋を備えたストーマ装具であって、袋内に上記のストーマ装具用消臭剤組成物を収納してなるストーマ装具を提供することにある。
Accordingly, an object of the present invention is to provide a deodorant composition for ostomy appliances that has an immediate effect on the odor of excrement etc. in a stoma appliance and that can be processed in a short time. There is to do.
Another object of the present invention is a stoma device provided with a bag for containing excrement etc., wherein the stoma device contains the above deodorant composition for the stoma device in the bag. There is to do.
本発明者らは、前記目的を達成すべく、消臭剤組成物の構成成分やその形状等について鋭意研究を重ねた結果、特定の消臭成分を用い、更にその形状を特定のものとすれば、ストーマ装具中の排泄物等の臭いに対して即効性があり、また、排泄物等の短時間での処理が可能になることを見出し、この知見に基づいて本発明を完成するに至った。
かくして、本発明によれば、ポリフェノールを含有することを特徴とするストーマ装具用消臭剤組成物が提供される。
また、本発明のストーマ装具用消臭剤組成物において、ポリフェノールの含有量が消臭剤組成物全重量の０．５％以上であることが好ましく、０．５〜７０％であることがより好ましい。
また、本発明によれば、０．０５以上のＤＰＰＨ単位を有することを特徴とするストーマ装具用消臭剤組成物が提供される。
本発明のストーマ装具用消臭剤組成物は、ポリフェノールを含有し、０．０５以上のＤＰＰＨ単位を有することが好ましい。
In order to achieve the above-mentioned object, the present inventors have conducted extensive research on the components and shapes of the deodorant composition, and as a result, used specific deodorant components and made the shape specific. For example, the present invention has been found to be effective immediately against the odor of excrement etc. in the stoma device, and to be able to process excrement etc. in a short time, and to complete the present invention based on this knowledge. It was.
Thus, according to the present invention, there is provided a deodorant composition for an ostomy appliance comprising polyphenol.
In the deodorant composition for stoma appliances of the present invention, the content of polyphenol is preferably 0.5% or more of the total weight of the deodorant composition, more preferably 0.5 to 70%. preferable.
In addition, according to the present invention, there is provided a deodorant composition for ostomy appliances having DPPH units of 0.05 or more.
The deodorant composition for stoma appliances of the present invention preferably contains polyphenol and has a DPPH unit of 0.05 or more.
上記本発明のストーマ装具用消臭剤組成物において、生理食塩水への溶解度が３０％以上であることが好ましい。
また、本発明のストーマ装具用消臭剤組成物は、生理食塩水への溶解後の粘度が７００ｍＰａ・ｓ以下であることが好ましい。
また、本発明のストーマ装具用消臭剤組成物は、生理食塩水への溶解後の拡散面積が７．０ｃｍ２以上であることが好ましい。
In the deodorant composition for stoma appliances of the present invention, the solubility in physiological saline is preferably 30% or more.
In addition, the deodorant composition for stoma appliances of the present invention preferably has a viscosity of 700 mPa · s or less after dissolution in physiological saline.
In addition, the deodorant composition for stoma appliances of the present invention preferably has a diffusion area of 7.0 cm 2 or more after dissolution in physiological saline.
本発明のストーマ装具用消臭剤組成物は、精油及び／又は親水性高分子化合物を含有することが好ましい。
また、精油及び親水性高分子化合物の含有量が、それぞれ、消臭剤組成物全重量の０．１〜５０％及び０．５〜７０％であることが好ましい。
上記本発明のストーマ装具用消臭剤組成物において、精油が親水性高分子化合物によりマイクロカプセル化されているものであることが好ましい。
また、本発明のストーマ装具用消臭剤組成物において、ポリフェノール、精油及び親水性高分子化合物の含有量が、それぞれ、消臭剤組成物全重量の１〜５０重量％、０．１〜３０％及び５〜６０重量％であり、ＤＰＰＨ単位が０．０５以上であることが好ましい。
更に、本発明のストーマ装具用消臭剤組成物において、ポリフェノール、精油、及び親水性高分子化合物の含有量が、それぞれ、消臭剤組成物全重量の１〜５０重量％、０．１〜３０％及び５〜６０重量％であり、ＤＰＰＨ単位が０．０５以上であり、生理食塩水への溶解後の粘度が７００ｍＰａ・ｓ以下であることが好ましい。
The deodorant composition for stoma appliances of the present invention preferably contains an essential oil and / or a hydrophilic polymer compound.
Moreover, it is preferable that content of an essential oil and a hydrophilic high molecular compound is 0.1 to 50% and 0.5 to 70% of a deodorant composition whole weight, respectively.
In the deodorant composition for stoma appliances of the present invention, the essential oil is preferably microencapsulated with a hydrophilic polymer compound.
Moreover, in the deodorant composition for stoma appliances of this invention, content of polyphenol, essential oil, and a hydrophilic polymer compound is 1-50 weight% of deodorant composition total weight, respectively, and 0.1-30. % And 5 to 60% by weight, and the DPPH unit is preferably 0.05 or more.
Furthermore, in the deodorant composition for stoma appliances of the present invention, the content of polyphenol, essential oil, and hydrophilic polymer compound is 1 to 50% by weight, 0.1 to 0.1% of the total weight of the deodorant composition, respectively. It is preferably 30% and 5 to 60% by weight, the DPPH unit is 0.05 or more, and the viscosity after dissolution in physiological saline is 700 mPa · s or less.
本発明のストーマ装具用消臭剤組成物は、粉体状であることができる。
上記粉体状の本発明のストーマ装具用消臭剤組成物は、フィルムへの付着率が１０〜８０％であることが好ましい。
上記粉体状の本発明のストーマ装具用消臭剤組成物において、粒径１５〜１，０００μｍの粉体の含有量が８０頻度％以上であることが好ましく、粒径１５〜５００μｍの粉体の含有量が７０頻度％以上であることがより好ましい。
また、上記粉体状の本発明のストーマ装具用消臭剤組成物において、ポリフェノール、精油及び親水性高分子化合物の含有量が、それぞれ、消臭剤組成物全重量の１〜５０重量％、０．１〜３０％及び５〜６０重量％であり、粒径１５〜１，０００μｍの粉体の含有量が８０頻度％以上であることが好ましく、粒径１５〜５００μｍの粉体の含有量が７０頻度％以上であることが更に好ましい。
本発明によれば、ポリフェノール、精油及び親水性高分子化合物の含有量が、それぞれ、消臭剤組成物全重量の１〜５０重量％、０．１〜３０％及び５〜６０重量％であり、フィルムへの付着率が１０〜８０％であり、且つ、粒径１５〜１，０００μｍの粉体の含有量が８０頻度％以上であるか、粒径１５〜５００μｍの粉体の含有量が７０頻度％以上である、粉体状のストーマ装具用消臭剤組成物が提供される。
The deodorant composition for stoma appliances of the present invention can be in powder form.
The powdery deodorant composition for stoma appliances of the present invention preferably has an adhesion rate to the film of 10 to 80%.
In the powdery deodorant composition for a stoma device of the present invention, the content of the powder having a particle size of 15 to 1,000 μm is preferably 80% by frequency or more, and the powder having a particle size of 15 to 500 μm The content of is more preferably 70% by frequency or more.
Moreover, in the powdery deodorant composition for a stoma device of the present invention, the content of polyphenol, essential oil and hydrophilic polymer compound is 1 to 50% by weight of the total weight of the deodorant composition, 0.1 to 30% and 5 to 60% by weight, and the content of powder having a particle size of 15 to 1,000 μm is preferably 80% by frequency or more, and the content of powder having a particle size of 15 to 500 μm Is more preferably 70 frequency% or more.
According to the present invention, the contents of polyphenol, essential oil and hydrophilic polymer compound are 1 to 50%, 0.1 to 30% and 5 to 60% by weight of the total weight of the deodorant composition, respectively. The adhesion rate to the film is 10 to 80%, and the content of the powder having a particle size of 15 to 1,000 μm is 80 frequency% or more, or the content of the powder having a particle size of 15 to 500 μm is A powdery deodorant composition for an ostomy appliance which is 70 frequency% or more is provided.
更に、本発明によれば、上記本発明のストーマ装具用消臭剤組成物を収納してなる、排泄物等を収容するための袋を備えたストーマ装具が提供される。 Furthermore, according to this invention, the stoma appliance provided with the bag for accommodating the excrement etc. which accommodates the deodorant composition for said stoma appliances of the said invention is provided.
本発明のストーマ装具用消臭剤組成物を使用することにより、排泄物等の悪臭を短時間で消臭することができ、ストーマ装具の交換頻度が高くても、排泄物等廃棄時の臭気の問題を生じることがない。
また、本発明のストーマ装具用消臭剤組成物を使用することにより、ストーマ装具からの排泄物等の取り出しが短時間で済むので、排泄物等の悪臭成分の拡散が低減され、排泄物等排出操作に伴う不快感も軽減される。
更に、本発明のストーマ装具用消臭剤組成物は、上記ストーマ装具用に限らず、おむつ、尿パッド、生理用ナプキン、医療用吸収パッド等の比較的長時間に亘って人体に装着されるその他の排泄物等処理用品用としても有効に使用することができる。
By using the deodorant composition for stoma devices of the present invention, it is possible to deodorize malodors such as excrement in a short time, and even when the stoma device is exchanged frequently, the odor at the time of disposal of excrement etc. No problems arise.
Further, by using the deodorant composition for the stoma device of the present invention, it is possible to take out the excrement etc. from the stoma device in a short time, so that the diffusion of malodorous components such as the excrement is reduced, the excrement etc. Discomfort associated with the discharge operation is also reduced.
Furthermore, the deodorant composition for a stoma device of the present invention is not limited to the above stoma device, but is worn on a human body for a relatively long time such as a diaper, a urine pad, a sanitary napkin, a medical absorbent pad and the like. It can also be used effectively for other excrement disposal products.
本発明のストーマ装具用消臭剤組成物（以下、単に「消臭剤組成物」ということがある。）は、ポリフェノールを含有することを特徴とする。
発明で使用されるポリフェノールとは、同一ベンゼン環にヒドロキシ基の数を２個以上有する多価の芳香族ヒドロキシ化合物及びその誘導体の総称である。
The deodorant composition for stoma appliances of the present invention (hereinafter sometimes simply referred to as “deodorant composition”) is characterized by containing polyphenol.
The polyphenol used in the invention is a general term for polyvalent aromatic hydroxy compounds having two or more hydroxy groups on the same benzene ring and derivatives thereof.
ポリフェノールの具体例としては、カテコール、４−メチルカテコール、５−メチルカテコール、レゾルシノール、２−メチルレゾルシノール、５−メチルレゾシノール、ハイドロキノン等のジフェノール類；４，４’−ビフェニルジオール、３，４’−ビフェニルジオール等のビフェニルジオール類；カテキン、エピカテキン、エピガロカテキン、エピカテキンガレート等のカテキン類；ドーパ、ドーパミン、クロロゲン酸、コーヒー酸、パラクマル酸、チロシン等のカテコール誘導体を挙げることができる。
中でも、植物から抽出等した植物由来のポリフェノール（以下、「植物ポリフェノール」という。）が好ましい。植物ポリフェノールは、その化学的作用によって即効性のある消臭効果を発揮し、更にその抗菌作用によっても消臭効果が持続する。
植物ポリフェノールとしては、例えば、コーヒー、リンゴ、ぶどう、茶類（緑茶、焙じ茶、紅茶、ウーロン茶、マテ茶等）、柿、大豆、カカオ、ローズマリー、アロエ等の由来のものが挙げられ、中でも、コーヒー、リンゴ、ぶどう、茶類（緑茶、焙じ茶、紅茶、ウーロン茶、マテ茶等）の抽出物が好ましい。
Specific examples of polyphenols include diphenols such as catechol, 4-methylcatechol, 5-methylcatechol, resorcinol, 2-methylresorcinol, 5-methylresorcinol, hydroquinone; 4,4′-biphenyldiol, 3, Biphenyldiols such as 4′-biphenyldiol; catechins such as catechin, epicatechin, epigallocatechin and epicatechin gallate; and catechol derivatives such as dopa, dopamine, chlorogenic acid, caffeic acid, paracoumaric acid and tyrosine it can.
Among these, plant-derived polyphenols extracted from plants (hereinafter referred to as “plant polyphenols”) are preferable. Plant polyphenol exhibits an immediate deodorizing effect due to its chemical action, and further maintains the deodorizing effect due to its antibacterial action.
Examples of plant polyphenols include those derived from coffee, apples, grapes, teas (green tea, roasted tea, black tea, oolong tea, mate tea, etc.), strawberries, soybeans, cacao, rosemary, aloe, etc. Extracts of coffee, apples, grapes, teas (green tea, roasted tea, black tea, oolong tea, mate tea, etc.) are preferred.
本発明において、ポリフェノールは、消臭剤組成物中に０.５重量％以上含有されていることが好ましく、０．５〜７０重量％の範囲で含有されていることがより好ましく、１〜５０重量％含有されていることが特に好ましい。０．５重量％より少ないと、十分な消臭効果が発揮されない可能性がある。 In the present invention, the polyphenol is preferably contained in an amount of 0.5% by weight or more in the deodorant composition, more preferably 0.5 to 70% by weight, and more preferably 1 to 50%. It is particularly preferable that it is contained by weight. If the amount is less than 0.5% by weight, the sufficient deodorizing effect may not be exhibited.
本発明のストーマ装具用消臭剤組成物は、ＤＰＰＨ（１，１-ジフェニル−２-ピクリルヒドラジル）ラジカル消去能試験において、０．０５以上のＤＰＰＨ単位を有するものであることが好ましく、０．１以上のＤＰＰＨ単位を有するものであることが、より好ましい。ＤＰＰＨ単位は、抗酸化能の指標であり、ＤＰＰＨ単位がこの範囲にあるとき、高い消臭効果を得ることができる。
本発明のストーマ装具用消臭剤組成物は、ポリフェノールを含有し、０．０５以上のＤＰＰＨ単位を有するものであることがより好ましい。
In the DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging ability test, the deodorant composition for stoma appliances of the present invention preferably has a DPPH unit of 0.05 or more, It is more preferable that it has 0.1 or more DPPH units. The DPPH unit is an index of antioxidant ability. When the DPPH unit is in this range, a high deodorizing effect can be obtained.
More preferably, the deodorant composition for stoma appliances of the present invention contains polyphenol and has a DPPH unit of 0.05 or more.
本発明のストーマ装具用消臭剤組成物は、生理食塩水への溶解度が３０％以上であることが好ましい。
生理食塩水への溶解度が３０％以上であることにより、排泄物等に接触した消臭剤組成物が速やかに溶解し拡散するので、消臭効果が速やかに発揮される。生理食塩水への溶解度は、４５％以上であることが好ましい。
The deodorant composition for stoma appliances of the present invention preferably has a solubility in physiological saline of 30% or more.
When the solubility in physiological saline is 30% or more, the deodorant composition that has come into contact with excreta and the like quickly dissolves and diffuses, so that the deodorizing effect is quickly exhibited. The solubility in physiological saline is preferably 45% or more.
本発明のストーマ装具用消臭剤組成物は、これを生理食塩水中に溶解して得られる濃度０．２ｇ／ｍｌの生理食塩水溶液の粘度が、７００ｍＰａ・ｓ以下であることが好ましく、３００ｍＰａ・ｓ以下であることが更に好ましい。下限は３ｍＰａ・ｓ程度である。この粘度が７００ｍＰａ・ｓより高いと、排泄物等の水分を吸収した後に消臭剤組成物の流動性がなくなるため、排泄物等を包み込むように広がっていくことができず、消臭機能が低下し、また、べたつきを生じて排泄物等の排出時に滑り性がなくなり、更に排泄物等の取出し時間が長くなることにより不快感が増大する恐れがある。
本発明のストーマ装具用消臭剤組成物の生理食塩水溶液の粘度は、親水性高分子化合物等の添加成分の種類や量で調整することができる。
In the deodorant composition for stoma device of the present invention, the viscosity of a physiological saline solution having a concentration of 0.2 g / ml obtained by dissolving this in a physiological saline solution is preferably 700 mPa · s or less, preferably 300 mPa · s. More preferably, it is s or less. The lower limit is about 3 mPa · s. If this viscosity is higher than 700 mPa · s, the fluidity of the deodorant composition will be lost after absorbing moisture such as excrement, so it cannot spread to wrap the excrement etc. In addition, there is a risk that stickiness may occur and slipping may be lost when excrement is discharged, and discomfort may increase due to a longer time for taking out excrement.
The viscosity of the physiological saline solution of the deodorant composition for stoma appliances of the present invention can be adjusted by the type and amount of additive components such as hydrophilic polymer compounds.
本発明のストーマ装具用消臭剤組成物は、上記濃度０．２ｇ／ｍｌの生理食塩水溶液の２ミリリットルの拡散面積が７．０ｃｍ２以上の範囲のものが好ましく、１０．０ｃｍ２以上の範囲のものが更に好ましい。拡散面積が７．０ｃｍ２以上であると、排泄物等の水分を吸収した後に消臭剤組成物が拡散し、排泄物等を包み込むように広がっていく。その結果、消臭機能が向上し、排泄物等のべたつきを減じて排泄物等の排出時に滑り性がよくなり、排泄物等の取出し時間が短くなることにより不快感を軽減することができる。 Ostomy appliance for deodorant composition of the present invention is preferably a 2 ml range diffusion area of 7.0 cm 2 or more of the saline solution the concentration of 0.2 g / ml, 10.0 cm 2 or more ranges Are more preferred. When the diffusion area is 7.0 cm 2 or more, the deodorant composition diffuses after absorbing moisture such as excrement and spreads so as to wrap the excrement and the like. As a result, the deodorization function is improved, the stickiness of the excrement etc. is reduced, the slipping property is improved when excrement etc. is discharged, and the discomfort can be reduced by shortening the time for taking out the excrement etc.
本発明のストーマ装具用消臭剤組成物は、消臭成分として、ポリフェノールに加えて、精油及び／又は親水性高分子化合物を含有することが好ましい。
本発明のストーマ装具用消臭剤組成物が精油を含有するとき、精油の香気によって悪臭成分がマスキングされるので、より一層、消臭効果が高められる。また、精油の中には、抗菌作用を有するものも多く、その抗菌作用によっても消臭効果が得られる。更に、精油は、排泄物等とストーマ装具の袋内表面との間で潤滑作用を発揮し、排泄物等の袋内表面からの除去を容易にするので、排泄物等排出操作に伴う不快感を軽減することができる。
The deodorant composition for stoma appliances of the present invention preferably contains an essential oil and / or a hydrophilic polymer compound in addition to polyphenol as a deodorizing component.
When the deodorant composition for stoma appliances of the present invention contains an essential oil, the malodorous component is masked by the aroma of the essential oil, so the deodorizing effect is further enhanced. In addition, many essential oils have antibacterial action, and the deodorizing effect can be obtained by the antibacterial action. In addition, the essential oil exerts a lubricating action between the excrement etc. and the inner surface of the stoma appliance bag, making it easy to remove the excrement etc. from the inner bag surface. Can be reduced.
精油としては、例えば、ペパーミント油、ミント油、スペアミント油、ハッカ油、ラベンダー油、グレープフルーツ油、オレンジ油、ティーツリー油、ローズマリー油、レモン油、ゆず油、ライム油、レモングラス油、タイム油、ベルガモット油、ネロリ油、ユーカリ油、チョウジ油、ケイヒ油、カミツレ油、ヒノキ油等を使用することができる。
これらの油は、１種類を単独で用いてもよく、２種類以上を併用してもよい。
また、消臭剤組成物中の精油の含有量は、消臭剤組成物の全重量に対して、０．１〜５０％であることが好ましく、０．１〜３０％であることが更に好ましい。精油の含有量が０．１％より少ないと、上記機能が十分に発揮されない可能性がある。他方、５０％よりも多いと、臭気が過剰となり、不快感を与える可能性がある。
Examples of essential oils include peppermint oil, mint oil, spearmint oil, mint oil, lavender oil, grapefruit oil, orange oil, tea tree oil, rosemary oil, lemon oil, yuzu oil, lime oil, lemongrass oil, thyme oil. Bergamot oil, neroli oil, eucalyptus oil, clove oil, cinnamon oil, chamomile oil, cypress oil and the like can be used.
These oils may be used alone or in combination of two or more.
Further, the content of the essential oil in the deodorant composition is preferably 0.1 to 50%, more preferably 0.1 to 30%, based on the total weight of the deodorant composition. preferable. If the essential oil content is less than 0.1%, the above functions may not be sufficiently exhibited. On the other hand, when it is more than 50%, the odor becomes excessive and there is a possibility of giving unpleasant feeling.
本発明のストーマ装具用消臭剤組成物において、潤滑作用を高めるために、精油に代えて又は精油とともに、植物油、鉱油、動物油、合成油等の精油以外の油を使用してもよい。
植物油の例としては、オリーブ油、オリーブスクワラン、マカデミアナッツ油、ホホバ油、ひまし油、やし油、パーム油、サフラワー油、ひまわり油、硬化やし油、硬化パーム油等を挙げることができる。
鉱油の例としては、流動パラフィン、流動イソパラフィン、ナフテン油等を挙げることができる。
動物油の例としては、ラノリン、タートル油、ミツロウ、スクワレン、プリスタン等を挙げることができる。
合成油としては、例えば、グリセリントリ−２−エチルヘキサノエート等の脂肪酸トリグリセライド；ポリメチルフェニルシロキサン、ポリジメチルシロキサン、アミノシリコン等のシリコーンオイル；ミリスチン酸イソプロピル、ミリスチン酸オクチルドデシル、イソノナン酸イソノニル、パルミチン酸イソプロピル、パルミチン酸エチルヘキシル等のエステル類；等を挙げることができる。
In the deodorant composition for stoma appliances of the present invention, oil other than essential oil such as vegetable oil, mineral oil, animal oil, synthetic oil, etc. may be used in place of or together with essential oil in order to enhance the lubricating action.
Examples of vegetable oils include olive oil, olive squalane, macadamia nut oil, jojoba oil, castor oil, palm oil, palm oil, safflower oil, sunflower oil, hardened palm oil, hardened palm oil and the like.
Examples of mineral oils include liquid paraffin, liquid isoparaffin, and naphthenic oil.
Examples of animal oils include lanolin, turtle oil, beeswax, squalene, pristane and the like.
Synthetic oils include, for example, fatty acid triglycerides such as glycerin tri-2-ethylhexanoate; silicone oils such as polymethylphenylsiloxane, polydimethylsiloxane, and aminosilicon; isopropyl myristate, octyldodecyl myristate, isononyl isononanoate, And esters such as isopropyl palmitate and ethylhexyl palmitate;
本発明のストーマ装具用消臭剤組成物が親水性高分子化合物を含有するとき、親水性高分子化合物が排泄物等中の水分を吸収保持するので、排泄物等を被覆して排泄物等中の悪臭成分が蒸散するのを防ぎ、また、悪臭成分を吸着するので消臭効果を持続させることができる。
親水性高分子化合物としては、天然、半合成又は合成の親水性高分子化合物を使用できる。
When the deodorant composition for the stoma device of the present invention contains a hydrophilic polymer compound, the hydrophilic polymer compound absorbs and retains moisture in the excrement etc., so the excrement etc. is covered with the excrement etc. It prevents the malodorous component from evaporating and adsorbs the malodorous component, so that the deodorizing effect can be maintained.
Natural, semi-synthetic or synthetic hydrophilic polymer compounds can be used as the hydrophilic polymer compound.
天然親水性高分子化合物の具体例としては、アラビアガム、トラガカントガム、ガラクタン、グアガム、キャロブガム、カラヤガム、カラギーナン、ペクチン、カンテン、デンプン（例えば、コメ、トウモロコシ、バレイショ、コムギ）等の植物系高分子；キサンタンガム、デキストリン、デキストラン、サクシノグルカン、プルラン等の微生物系高分子；コラーゲン、カゼイン、アルブミン、ゼラチン等の動物系高分子；等が挙げられる。 Specific examples of natural hydrophilic polymer compounds include plant-based polymers such as gum arabic, gum tragacanth, galactan, guar gum, carob gum, caraya gum, carrageenan, pectin, starch, (eg, rice, corn, potato, wheat); And microbial polymers such as xanthan gum, dextrin, dextran, succinoglucan, and pullulan; animal polymers such as collagen, casein, albumin, and gelatin;
半合成親水性高分子化合物の具体例としては、デンプン系高分子（例えば、カルボキシメチルデンプン、メチルヒドロキシプロピルデンプン等）；セルロース系高分子（例えば、メチルセルロース、エチルセルロース、メチルヒドロキシプロピルセルロース、ヒドロキシエチルセルロース、セルロース硫酸ナトリウム、ヒドロキシプロピルセルロース、カルボキシメチルセルロース、カルボキシメチルセルロースナトリウム等）；アルギン酸系高分子（例えば、アルギン酸ナトリウム、アルギン酸プロピレングリコールエステル等）等が挙げられる。 Specific examples of semi-synthetic hydrophilic polymer compounds include starch polymers (eg, carboxymethyl starch, methylhydroxypropyl starch, etc.); cellulosic polymers (eg, methylcellulose, ethylcellulose, methylhydroxypropylcellulose, hydroxyethylcellulose, Cellulose sodium sulfate, hydroxypropyl cellulose, carboxymethyl cellulose, carboxymethyl cellulose sodium, etc.); alginic acid polymers (for example, sodium alginate, propylene glycol alginate, etc.) and the like.
合成親水性高分子化合物の具体例としては、ビニル系高分子（例えば、ポリビニルアルコール、ポリビニルメチルエーテル、ポリビニルピロリドン、カルボキシビニルポリマー等）；ポリオキシエチレン系高分子（例えば、ポリエチレングリコール、ポリオキシエチレン・ポリオキシプロピレン共重合体等）；アクリル系高分子（例えば、ポリアクリル酸ナトリウム、ポリアクリルアミド等）；ポリエチレンイミン；等が挙げられる。 Specific examples of the synthetic hydrophilic polymer compound include vinyl polymers (eg, polyvinyl alcohol, polyvinyl methyl ether, polyvinyl pyrrolidone, carboxyvinyl polymer); polyoxyethylene polymers (eg, polyethylene glycol, polyoxyethylene). -Polyoxypropylene copolymer etc.); Acrylic polymer (for example, sodium polyacrylate, polyacrylamide etc.); Polyethyleneimine;
親水性高分子化合物は、水溶性のものでも非水溶性のものでもよい。
非水溶性の親水性高分子化合物としては、水溶性親水性高分子化合物を架橋等によって非水溶性化したものが使用できる。その具体例としては、架橋カルボキシメチルセルロース、デンプン−アクリルニトリルグラフト共重合体、スターチグリコール酸ナトリウム、架橋デキストラン、架橋ポリビニルピロリドン等が挙げられる。
The hydrophilic polymer compound may be water-soluble or water-insoluble.
As the water-insoluble hydrophilic polymer compound, a water-soluble hydrophilic polymer compound that has been rendered water-insoluble by crosslinking or the like can be used. Specific examples thereof include crosslinked carboxymethylcellulose, starch-acrylonitrile graft copolymer, sodium starch glycolate, crosslinked dextran, and crosslinked polyvinylpyrrolidone.
親水性高分子化合物の含有量は、０．５〜７０重量％であることが好ましく、５〜６０重量％であることが更に好ましい。親水性高分子化合物の含有量が０．５重量％より少ないと、消臭効果が十分に発揮されない可能性がある。他方、７０重量％よりも多いと、水分を吸収した親水性高分子化合物がべたつきを生じ、排泄物等の取り出しが困難になる場合がある。 The content of the hydrophilic polymer compound is preferably 0.5 to 70% by weight, and more preferably 5 to 60% by weight. If the content of the hydrophilic polymer compound is less than 0.5% by weight, the deodorizing effect may not be sufficiently exhibited. On the other hand, when it is more than 70% by weight, the hydrophilic polymer compound that has absorbed moisture may become sticky and it may be difficult to take out excreta and the like.
本発明のストーマ装具用消臭剤組成物において、上記精油及び親水性高分子化合物を併用することが好ましい。精油及び親水性高分子化合物を併用する場合には、精油及び親水性高分子化合物の量は、それぞれ、消臭剤組成物全重量の０．１〜５０重量％及び０．５〜７０重量％であることが好ましく、それぞれ、０．１〜３０重量％及び５〜６０重量％であることが更に好ましい。精油及び親水性高分子化合物のバランスにより、消臭の持続性が発揮され、更に排泄物等に滑り性が付与されるため排出操作が簡便となる。 In the deodorant composition for stoma appliances of this invention, it is preferable to use together the said essential oil and a hydrophilic high molecular compound. When the essential oil and the hydrophilic polymer compound are used in combination, the amounts of the essential oil and the hydrophilic polymer compound are 0.1 to 50% by weight and 0.5 to 70% by weight, respectively, of the total weight of the deodorant composition. It is preferable that it is 0.1-30 weight% and 5-60 weight%, respectively. Due to the balance of the essential oil and the hydrophilic polymer compound, the deodorization persistence is exhibited, and the excretion and the like are given slipperiness, thereby simplifying the discharging operation.
本発明のストーマ装具用消臭剤組成物において、上記精油及び親水性高分子化合物を併用するに当っては、親水性高分子化合物を、精油の固体化のために使用することが好ましく、特に、親水性高分子化合物により精油をマイクロカプセル化することが好ましい。
精油をマイクロカプセル化することにより、排出される排泄物等の量の程度に応じて親水性高分子が溶解し、精油を徐々に放出させることができるので、消臭能力を効率的かつ持続的に発揮させることが可能となる。
また、排泄物等をストーマ装具のパウチから排出する際には、マイクロカプセルとパウチ表面との摩擦でマイクロカプセルが破壊され、精油の芳香が発散されるので、排出作業時にも優れた消臭効果を発揮する。
In the deodorant composition for the stoma device of the present invention, when the essential oil and the hydrophilic polymer compound are used in combination, the hydrophilic polymer compound is preferably used for solidifying the essential oil. The essential oil is preferably microencapsulated with a hydrophilic polymer compound.
By microencapsulating the essential oil, the hydrophilic polymer dissolves and the essential oil can be released gradually according to the amount of excreta discharged, etc., so the deodorizing ability is efficient and sustainable Can be demonstrated.
In addition, when excrement etc. is discharged from the pouch of the stoma device, the microcapsule is destroyed by the friction between the microcapsule and the pouch surface, and the fragrance of the essential oil is emitted. Demonstrate.
本発明のストーマ装具用消臭剤組成物において、ポリフェノール、精油及び親水性高分子化合物の含有量が、それぞれ、消臭剤組成物全重量の１〜５０重量％、０．１〜３０％及び５〜６０重量％であり、ＤＰＰＨ単位が０．０５以上であることが好ましい。
また、本発明のストーマ装具用消臭剤組成物において、ポリフェノール、精油、及び親水性高分子化合物の含有量が、それぞれ、消臭剤組成物全重量の１〜５０重量％、０．１〜３０％及び５〜６０重量％であり、ＤＰＰＨ単位が０．０５以上であり、生理食塩水への溶解後の粘度が７００ｍＰａ・ｓ以下であることが好ましい。
In the deodorant composition for the stoma device of the present invention, the content of polyphenol, essential oil and hydrophilic polymer compound is 1 to 50% by weight, 0.1 to 30% of the total weight of the deodorant composition, and It is preferably 5 to 60% by weight, and the DPPH unit is preferably 0.05 or more.
Further, in the deodorant composition for the stoma device of the present invention, the content of polyphenol, essential oil, and hydrophilic polymer compound is 1 to 50% by weight of the total weight of the deodorant composition, 0.1 to 0.1%, respectively. 30% and 5 to 60% by weight, the DPPH unit is 0.05 or more, and the viscosity after dissolution in physiological saline is preferably 700 mPa · s or less.
本発明のストーマ装具用消臭剤組成物は、上記ポリフェノール、精油及び親水性高分子化合物以外の成分を含有してもよい。
これらの任意成分としては、界面活性剤、粉体、ｐＨ調整剤、着色剤、ポリフェノール以外の消臭性化合物、等を示すことができる。
The deodorant composition for stoma appliances of this invention may contain components other than the said polyphenol, essential oil, and a hydrophilic high molecular compound.
Examples of these optional components include surfactants, powders, pH adjusters, colorants, deodorant compounds other than polyphenols, and the like.
界面活性剤は、非イオン界面活性剤、アニオン界面活性剤、カチオン界面活性剤及び両性界面活性剤のいずれでもよい。
非イオン界面活性剤の具体例としては、ポリオキシエチレンアルキルエーテル、ポリオキシエチレン２級アルコールエーテル、ポリオキシエチレンラノリン誘導体、ポリオキシエチレンポリオキシプロピレンブロックポリマー等のエーテル型；ポリオキシエチレングリセリン脂肪酸エステル、ポリオキシエチレンソルビタン脂肪酸エステル、ポリオキシエチレンソルビトール脂肪酸エステル等のエーテルエステル型；ポリエチレングリコール脂肪酸エステル、ポリグリセリン脂肪酸エステル、ソルビタン脂肪酸エステル、プロピレングリコール脂肪酸エステル、ショ糖脂肪酸エステル等のエステル型；脂肪酸アルカノールアミド、ポリオキシエチレン脂肪酸アミド、ポリオキシエチレンアルキルアミン等の含窒素型；等を挙げることができる。
The surfactant may be any of a nonionic surfactant, an anionic surfactant, a cationic surfactant and an amphoteric surfactant.
Specific examples of the nonionic surfactant include ether types such as polyoxyethylene alkyl ether, polyoxyethylene secondary alcohol ether, polyoxyethylene lanolin derivative, polyoxyethylene polyoxypropylene block polymer; polyoxyethylene glycerin fatty acid ester , Ether ester types such as polyoxyethylene sorbitan fatty acid ester and polyoxyethylene sorbitol fatty acid ester; ester types such as polyethylene glycol fatty acid ester, polyglycerin fatty acid ester, sorbitan fatty acid ester, propylene glycol fatty acid ester and sucrose fatty acid ester; fatty acid alkanol Nitrogen-containing type such as amide, polyoxyethylene fatty acid amide, polyoxyethylene alkylamine, etc.
アニオン界面活性剤の具体例としては、脂肪酸石鹸、アルキルエーテルカルボン酸塩等のカルボン酸塩；アルキルベンゼンスルホン酸塩、ジアルキルスルホコハク酸エステル塩、α−オレフィンスルホン酸塩等のスルホン酸塩；高級アルコール硫酸エステル塩、第２級高級アルコール硫酸エステル塩、アルキルエーテル硫酸塩、ポリオキシエチレンアルキルフェニルエーテル硫酸塩等の硫酸エステル塩；アルキルエーテルリン酸エステル塩、アルキルリン酸エステル塩等のリン酸エステル塩；等を挙げることができる。
カチオン界面活性剤の具体例としては、脂肪族アミン塩、脂肪族４級アンモニウム塩、ベンザルコニウム塩；等を挙げることができる。
両性界面活性剤の具体例としては、カルボキシベタイン型、アミノカルボン酸塩、レシチン；等を挙げることができる。
Specific examples of anionic surfactants include carboxylates such as fatty acid soaps and alkyl ether carboxylates; sulfonates such as alkylbenzene sulfonates, dialkylsulfosuccinates and α-olefin sulfonates; higher alcohol sulfates Ester salts, secondary higher alcohol sulfates, sulfates such as alkyl ether sulfates, polyoxyethylene alkylphenyl ether sulfates; phosphate esters such as alkyl ether phosphates and alkyl phosphates; Etc.
Specific examples of the cationic surfactant include aliphatic amine salts, aliphatic quaternary ammonium salts, and benzalkonium salts.
Specific examples of the amphoteric surfactant include carboxybetaine type, aminocarboxylate, lecithin;
これらの界面活性剤は、１種を単独で用いてもよく、２種以上を混合して用いてもよい。界面活性剤の使用量は、特に限定されないが、通常、消臭剤組成物全重量に対して０．０１〜１０重量％の範囲である。
本発明のストーマ装具用消臭剤組成物において、界面活性剤は、消臭機能を有すると共に、精油と同様に排泄物等とストーマ装具のパウチ内表面との間で潤滑作用を発揮し、排泄物等のストーマ装具からの除去を容易にするものと考えられる。
One of these surfactants may be used alone, or two or more thereof may be mixed and used. Although the usage-amount of surfactant is not specifically limited, Usually, it is the range of 0.01 to 10 weight% with respect to the deodorant composition total weight.
In the deodorant composition for the stoma device of the present invention, the surfactant has a deodorizing function and, like the essential oil, exerts a lubricating action between the excrement and the inner surface of the pouch of the stoma device, and excretes. It is considered that it facilitates removal of objects and the like from stoma appliances.
本発明のストーマ装具用消臭剤組成物に添加し得る粉体の具体例としては、ポリ（メタ）アクリル酸アルキルエステル系共重合体パウダー等のアクリル系パウダー、ナイロンパウダー、フッ素コーティングパウダー、ウレタンパウダー、シリコーンパウダー、酸化亜鉛、酸化チタン、窒化ホウ素、シルクパウダー、セルロースパウダー、マイカ、セリサイト、カオリン、炭酸カルシウム、炭酸マグネシウム、珪酸アルミニウム、珪酸マグネシウム、シリカ、アルミナ、ベントナイト、スメクタイト等が挙げられる。
これらのうち、アクリル系パウダー、ナイロンパウダー、フッ素コーティングパウダー、ウレタンパウダー、シリコーンパウダー、酸化亜鉛、酸化チタン、窒化ホウ素等の非水溶性の粉体が排泄物等のべたつきを減じて、排泄物等の潤滑性が向上するため好ましい。
Specific examples of the powder that can be added to the deodorant composition for the stoma device of the present invention include acrylic powder such as poly (meth) acrylic acid alkyl ester copolymer powder, nylon powder, fluorine coating powder, and urethane. Examples include powder, silicone powder, zinc oxide, titanium oxide, boron nitride, silk powder, cellulose powder, mica, sericite, kaolin, calcium carbonate, magnesium carbonate, aluminum silicate, magnesium silicate, silica, alumina, bentonite, and smectite. .
Of these, non-water-soluble powders such as acrylic powder, nylon powder, fluorine coating powder, urethane powder, silicone powder, zinc oxide, titanium oxide, boron nitride reduce the stickiness of excrement, etc. This is preferable because the lubricity is improved.
粉体の形状は、特に限定されず、球状、棒状、針状、板状、不定形状、燐片状、紡錘状等のいずれであってもよい。
粉体は、１種を単独で用いてもよく、２種以上を混合して用いてもよい。
粉体の使用量は、特に限定されないが、通常、消臭剤組成物全重量に対して５〜４０重量％の範囲である。
The shape of the powder is not particularly limited, and may be any of spherical shape, rod shape, needle shape, plate shape, irregular shape, flake shape, spindle shape, and the like.
As the powder, one kind may be used alone, or two or more kinds may be mixed and used.
Although the usage-amount of powder is not specifically limited, Usually, it is the range of 5-40 weight% with respect to the deodorant composition whole weight.
本発明のストーマ装具用消臭剤組成物は、そのｐＨが４．０〜７．０の範囲内にあることが好ましく、４．５〜６．５の範囲内にあることが更に好ましい。
ｐＨがこの範囲内にあると、消臭剤組成物が皮膚や粘膜に接触しても、これらに害を及ぼすことがない。
消臭剤組成物のｐＨを調整するには、ｐＨ調整剤を用いるのが好ましい。
ｐＨ調整剤としては、クエン酸、酒石酸、マレイン酸、コハク酸、リンゴ酸、乳酸、アスコルビン酸等の有機酸やその塩又はアルカリ金属水酸化物等を使用することができる。
The deodorant composition for stoma appliances of the present invention preferably has a pH in the range of 4.0 to 7.0, and more preferably in the range of 4.5 to 6.5.
When the pH is within this range, even if the deodorant composition comes into contact with the skin or mucous membrane, there is no harm to them.
In order to adjust the pH of the deodorant composition, it is preferable to use a pH adjuster.
As the pH adjuster, organic acids such as citric acid, tartaric acid, maleic acid, succinic acid, malic acid, lactic acid, ascorbic acid, salts thereof, alkali metal hydroxides, and the like can be used.
本発明のストーマ装具用消臭剤組成物は、ポリフェノール以外の消臭性化合物を含有していてもよい。
ポリフェノール以外の消臭性化合物は、特に限定されず、化学的消臭性化合物や生物学的消臭性化合物等が使用できる。
化学的消臭性化合物は、有機系消臭性化合物であっても無機系消臭性化合物であってもよい。
The deodorant composition for stoma appliances of the present invention may contain a deodorant compound other than polyphenol.
Deodorant compounds other than polyphenols are not particularly limited, and chemical deodorant compounds, biological deodorant compounds, and the like can be used.
The chemical deodorant compound may be an organic deodorant compound or an inorganic deodorant compound.
有機酸化合物としては、カルボン酸、スルホン酸等の有機酸及びこれらの塩を用いることができる。その具体例としては、酢酸、シュウ酸、クエン酸、マロン酸、コハク酸、グルタル酸、フマル酸、リンゴ酸、酒石酸、マレイン酸、アクリル酸、乳酸、フタル酸、安息香酸、ニコチン酸等を挙げることができる。これらは、ベタイン化合物の形態であってもよい。
エステル化合物の具体例としては、有機酸のエステル化合物を用いることができる。その具体例としては、（メタ）アクリル酸エステル、マレイン酸エステル等を挙げることができる。
アルデヒド化合物の具体例としては、グリオキザール等を挙げることができる。
第４級アンモニウム塩の具体例としては、塩化ベンザルコニウム、塩化ベンゼトニウム、アルキルジアミノエチルグリシン塩酸塩等を挙げることができる。
As the organic acid compound, organic acids such as carboxylic acid and sulfonic acid and salts thereof can be used. Specific examples thereof include acetic acid, oxalic acid, citric acid, malonic acid, succinic acid, glutaric acid, fumaric acid, malic acid, tartaric acid, maleic acid, acrylic acid, lactic acid, phthalic acid, benzoic acid, nicotinic acid and the like. be able to. These may be in the form of betaine compounds.
As a specific example of the ester compound, an ester compound of an organic acid can be used. Specific examples thereof include (meth) acrylic acid esters and maleic acid esters.
Specific examples of the aldehyde compound include glyoxal.
Specific examples of the quaternary ammonium salt include benzalkonium chloride, benzethonium chloride, alkyldiaminoethylglycine hydrochloride and the like.
無機系消臭性化合物としては、炭酸ナトリウム、炭酸水素ナトリウム、炭酸カルシウム等の炭酸塩；酸化カルシウム、酸化マグネシウム、酸化アルミニウム、酸化亜鉛、酸化銅、酸化鉄、酸化チタン、ミョウバン等の金属酸化物；二酸化塩素等が挙げられる。 Examples of inorganic deodorant compounds include carbonates such as sodium carbonate, sodium bicarbonate, and calcium carbonate; metal oxides such as calcium oxide, magnesium oxide, aluminum oxide, zinc oxide, copper oxide, iron oxide, titanium oxide, and alum Chlorine dioxide and the like.
生物学的消臭性化合物としては、酵素、微生物（細菌、酵母等）等の有機物分解作用を有するもの、及びエタノール、フェノキシエタノール、メチルパラベン、エチルパラベン、ブチルパラベン、プロピルパラベン等の防腐・殺菌作用を有する化合物が使用できる。 Biological deodorant compounds include those that decompose organic substances such as enzymes and microorganisms (bacteria, yeast, etc.), and antiseptic and bactericidal effects such as ethanol, phenoxyethanol, methylparaben, ethylparaben, butylparaben, and propylparaben. Can be used.
本発明のストーマ装具用消臭剤組成物の形態は、粉体状、粒状、ブロック状、液状、シート状、袋状、霧状、泡状、クリーム状等の形態から適宜選択できるが、粉体状、液状、シート状又は袋状であることが好ましく、粉体状であることが特に好ましい。 The deodorant composition for the stoma device of the present invention can be appropriately selected from powder, granular, block-like, liquid, sheet-like, bag-like, mist-like, foam-like, cream-like, etc. It is preferably in the form of a body, liquid, sheet or bag, and particularly preferably in the form of powder.
本発明のストーマ装具用消臭剤組成物の形態が粉体状であるとき、消臭剤組成物とストーマ装具のパウチ内表面との接触面積を小さくすることができ、これによって摩擦が低減されるので、排泄物等の滑り性を向上させることができる。
粉体状の消臭剤組成物は、粒径１５〜１，０００μｍの粉体を８０頻度％以上含有することが好ましく、粒径１５〜５００μｍの粉体を７０頻度％以上含むことが更に好ましく、粒径１５〜２５０μｍの粉体を７０頻度％以上含むことが特に好ましい。
When the deodorant composition for the stoma device of the present invention is in a powder form, the contact area between the deodorant composition and the pouch inner surface of the stoma device can be reduced, thereby reducing friction. Therefore, the slipperiness of excrement etc. can be improved.
The powdery deodorant composition preferably contains 80% by frequency or more of powder having a particle size of 15 to 1,000 μm, more preferably 70% by frequency or more of powder having a particle size of 15 to 500 μm. It is particularly preferable to contain 70 frequency% or more of powder having a particle size of 15 to 250 μm.
粒径１５〜１，０００μｍの粉体の頻度分布が８０頻度％以上あるとき、消臭剤組成物をストーマ装具のパウチ内に投入し易く、また、投入された消臭剤組成物がパウチ内で拡散し、排泄物等の水分に対する溶解性が良好なものとなるので、即効性のある消臭効果を得ることができる。更に、この範囲の頻度分布により、消臭剤組成物とストーマ装具のパウチ内表面との接触面積を小さくすることができ、これによって摩擦が低減されるので、排泄物等の滑り性を向上させ、排泄物等排出操作に伴う不快感を軽減することができる。この粉体状の消臭剤組成物の平均粒径は、１５〜１，０００μｍであることが好ましく、平均粒径１５〜５００μｍであることが更に好ましい。 When the frequency distribution of the powder having a particle size of 15 to 1,000 μm is 80 frequency% or more, the deodorant composition can be easily put into the pouch of the stoma device, and the deodorant composition is put in the pouch. Since it is diffused and the solubility in water such as excreta becomes good, an immediate deodorizing effect can be obtained. In addition, the frequency distribution within this range can reduce the contact area between the deodorant composition and the pouch inner surface of the stoma appliance, thereby reducing friction and improving the slipperiness of excrement etc. In addition, the discomfort associated with the excrement discharge operation can be reduced. The average particle size of the powdery deodorant composition is preferably 15 to 1,000 μm, and more preferably 15 to 500 μm.
消臭剤組成物の粉体形状は、特に限定されないが、球状、棒状、針状、板状、不定形状、燐片状、紡錘状等のいずれであってもよい。粉体表面に、窪みや突起などの凹凸を多数設けると、粉体の表面積が増大され、更に、水に対する溶解性が高まるので、消臭効果をより高めることができる。 The powder shape of the deodorant composition is not particularly limited, and may be any of spherical shape, rod shape, needle shape, plate shape, irregular shape, flake shape, spindle shape, and the like. When many irregularities such as depressions and protrusions are provided on the powder surface, the surface area of the powder is increased and the solubility in water is further increased, so that the deodorizing effect can be further enhanced.
本発明のストーマ装具用消臭剤組成物が粉体状であるとき、フィルムへの付着率が１０〜８０％であることが好ましい。フィルムへの付着率は、１５〜８０％であることが好ましく、２０〜６０％であることが更に好ましい。
フィルムへの付着率がこの範囲にあると、消臭剤組成物をストーマ装具のパウチ内に投入したときに、パウチフィルムに広範囲にわたって消臭剤組成物が付着するので、パウチ内に流入する排泄物等と消臭剤組成物との接触機会が増え、消臭の即効性を高めることができる。付着率が１０％以下であると、排泄物等と消臭剤組成物との接触機会が十分でなく消臭効果が低下する恐れがある。また、パウチから排泄物等を取り出す際には、一般的にパウチの下部に設けられた排出口を開放して、そこから排泄物等を排出させるが、排出口を開放した瞬間に強い臭気が発生する。そのため、排出口が設けられたパウチ内の下部（底部）に適量の消臭剤組成物を存在させ、局所的に消臭効果を高めることが排出時の消臭においては有効であり、フィルムへの付着率を８０％以下、好ましく６０％以下にすることによって、パウチ内の下部（底部）に消臭に有効な量の消臭剤組成物を存在させることができる。
When the deodorant composition for stoma devices of this invention is a powder form, it is preferable that the adhesion rate to a film is 10 to 80%. The adhesion rate to the film is preferably 15 to 80%, more preferably 20 to 60%.
When the adhesion rate to the film is within this range, when the deodorant composition is put into the pouch of the stoma device, the deodorant composition adheres to the pouch film over a wide range, so excretion flowing into the pouch. The chance of contact between the product and the deodorant composition increases, and the immediate effect of deodorization can be enhanced. If the adhesion rate is 10% or less, there is a possibility that the excretion etc. and the deodorant composition are not sufficiently contacted and the deodorizing effect is lowered. Moreover, when taking out excrement etc. from a pouch, generally the discharge port provided in the lower part of the pouch is opened, and excrement etc. is discharged from there, but strong odor is instantly when the discharge port is opened. appear. Therefore, it is effective for deodorization at the time of discharge to make a deodorant composition in an appropriate amount in the lower part (bottom part) of the pouch provided with a discharge port and to enhance the deodorization effect locally. By making the adhesion rate of 80% or less, preferably 60% or less, a deodorant composition in an amount effective for deodorization can be present in the lower part (bottom part) of the pouch.
本発明のストーマ装具用消臭剤組成物において、ポリフェノール、精油及び親水性高分子化合物の含有量が、それぞれ、消臭剤組成物全重量の１〜５０重量％、０．１〜３０％及び５〜６０重量％であり、粒径１５〜１，０００μｍの粉体の含有量が８０頻度％以上であることが好ましく、粒径１５〜５００μｍの粉体の含有量が７０頻度％以上であることが更に好ましい。 In the deodorant composition for the stoma device of the present invention, the content of polyphenol, essential oil and hydrophilic polymer compound is 1 to 50% by weight, 0.1 to 30% of the total weight of the deodorant composition, and It is preferably 5 to 60% by weight, and the content of powder having a particle size of 15 to 1,000 μm is preferably 80 frequency% or more, and the content of powder having a particle size of 15 to 500 μm is 70 frequency% or more. More preferably.
更に、本発明のストーマ装具用消臭剤組成物は、ポリフェノール、精油及び親水性高分子化合物の含有量が、それぞれ、消臭剤組成物全重量の１〜５０重量％、０．１〜３０％及び５〜６０重量％であり、フィルムへの付着率が１０〜８０％であり、且つ、粒径１５〜１，０００μｍの粉体の含有量が８０頻度％以上であるか、粒径１５〜５００μｍの粉体の含有量が７０頻度％以上である、粉体状のストーマ装具用消臭剤組成物であることが特に好ましい。 Furthermore, in the deodorant composition for stoma appliances of the present invention, the content of polyphenol, essential oil and hydrophilic polymer compound is 1 to 50% by weight, 0.1 to 30% of the total weight of the deodorant composition, respectively. % And 5 to 60% by weight, the adhesion rate to the film is 10 to 80%, and the content of the powder having a particle size of 15 to 1,000 μm is 80 frequency% or more, or a particle size of 15 It is particularly preferable that the powder is a deodorant composition for a stoma device having a powder content of ˜500 μm of 70 frequency% or more.
粉体状消臭剤組成物の調製方法は、特に限定されず、蒸発濃縮、噴射乾燥、粉砕、押出造粒、撹拌混合造粒等の方法を用いることができ、消臭剤組成物の構成成分ごと、又は複数成分の混合物として粉体を製造することができる。 The method for preparing the powdery deodorant composition is not particularly limited, and methods such as evaporation concentration, spray drying, pulverization, extrusion granulation, stirring and mixing granulation can be used. The powder can be produced for each component or as a mixture of multiple components.
本発明のストーマ装具用消臭剤組成物は、溶液、乳濁液、分散液等の液状形態であってもよい。液状の消臭剤組成物は、水や油等などの溶媒に消臭剤組成物の各成分を溶解、乳濁又は懸濁させることによって調製することができる。 The deodorant composition for stoma appliances of the present invention may be in a liquid form such as a solution, an emulsion, or a dispersion. The liquid deodorant composition can be prepared by dissolving, emulsifying, or suspending each component of the deodorant composition in a solvent such as water or oil.
本発明のストーマ装具用消臭剤組成物は、シート状又は袋状の形態であってもよい。
シート状又は袋状の消臭剤組成物は、シート状又は袋状の支持体にポリフェノール等の消臭成分を付着するか又は練り込むことによって形成することができる。支持体は、親水性高分子化合物をインフレーション法、Ｔダイ法、カレンダー法、押し出し法、吹き込み法等のシート成形方法によって形成する方法、又は水解性の繊維から紙、不織布、編布、織布等を形成する方法によって得ることができる。
シート状又は袋状の消臭剤組成物において、シート又は袋が水解性であることが好ましい。ここで、水解性とは、水流又は多量の水と接触するとバラバラに崩壊する性質のことを指すが、水に溶けて均一溶液となる「水溶性」の性質も含む概念である。
消臭剤組成物を水解性のシート又は袋にすることで、排泄物等をシート又は袋全体で包み込み、1つの塊として取り扱うことができるので、排泄物等の取り出し作業が非常に簡便となり、しかも、取り出した排泄物等は消臭剤組成物ごと、そのままトイレに流すことができ、廃棄操作も容易である。
The deodorant composition for stoma appliances of the present invention may be in the form of a sheet or bag.
A sheet-like or bag-like deodorant composition can be formed by attaching or kneading a deodorizing component such as polyphenol to a sheet-like or bag-like support. The support is formed by a method of forming a hydrophilic polymer compound by a sheet forming method such as an inflation method, a T-die method, a calendering method, an extrusion method, or a blowing method, or a paper, nonwoven fabric, knitted fabric, or woven fabric from water-degradable fibers. Etc. can be obtained by a method of forming the like.
In the sheet-like or bag-like deodorant composition, the sheet or bag is preferably water-degradable. Here, water decomposability refers to the property of disintegrating apart when it comes into contact with a water stream or a large amount of water, but is also a concept including the property of “water solubility” that dissolves in water to form a uniform solution.
By making the deodorant composition into a water-degradable sheet or bag, it is possible to wrap the excrement etc. in the whole sheet or bag and handle it as one lump, so the excrement etc. can be taken out very easily, Moreover, the excrement and the like taken out can be flushed together with the deodorant composition to the toilet, and the disposal operation is easy.
本発明のストーマ装具用消臭剤組成物は、ストーマ装具に適用するのに好適である。この消臭剤組成物は、使用の都度、必要量をストーマ装具のパウチ内に添加してもよく、また、予め複数回使用可能な量をパウチ内に添加しておいてもよい。消臭剤組成物は、パウチ内に挿入しやすい筒状の容器や袋に入れておくのが便利である。
また、本発明のストーマ装具用消臭剤組成物は、上記ストーマ装具用に限らず、おむつ、尿パッド、生理用ナプキン、医療用吸収パッド等の比較的長時間に亘って人体に装着されるその他の排泄物等処理用品用としても有効に使用することができる。
The deodorant composition for a stoma device of the present invention is suitable for application to a stoma device. Each time the deodorant composition is used, a necessary amount may be added to the pouch of the stoma device, or an amount that can be used a plurality of times may be added to the pouch in advance. The deodorant composition is conveniently placed in a cylindrical container or bag that can be easily inserted into a pouch.
The deodorant composition for stoma appliances of the present invention is not limited to the above-mentioned stoma appliance, but is worn on the human body over a relatively long period of time such as diapers, urine pads, sanitary napkins, medical absorbent pads, etc. It can also be used effectively for other excrement disposal products.
本発明のストーマ装具は、排泄物等を収容するための袋を備えたストーマ装具であって、パウチ内に本発明のストーマ装具用消臭剤組成物を収納してなる。
本発明のストーマ装具用消臭剤組成物を、ストーマ装具のパウチ内に収納しておくことにより、ストーマ装具を使用した後、排泄物等又はストーマ装具を廃棄処理等する際の不快臭を抑制することができる。
The ostomy appliance of the present invention is an ostomy appliance provided with a bag for containing excreta and the like, and the deodorant composition for an ostomy appliance of the present invention is housed in a pouch.
By storing the deodorant composition for the stoma device of the present invention in the pouch of the stoma device, after use of the stoma device, the excrement etc. or the unpleasant odor when the stoma device is disposed of is suppressed. can do.
ストーマ装具のパウチ内に収納する消臭剤組成物は、使用の都度、必要量をパウチ内に添加してもよく、また、複数回使用可能な量の消臭剤組成物をパウチ内に収納しておいてもよい。収納する消臭剤組成物の量や形態は、装具を交換する頻度、排泄物等の性状等を目安に決めればよい。 The deodorant composition stored in the pouch of the stoma device may be added to the pouch every time it is used, and the deodorant composition that can be used multiple times is stored in the pouch. You may keep it. The amount and form of the deodorant composition to be stored may be determined based on the frequency of exchanging the brace, the properties of excrement, and the like.
本発明のストーマ装具用消臭剤組成物をストーマ装具のパウチ内に収納するには、単に消臭剤組成物をパウチ内に入れておくだけでもよいし、消臭剤組成物を接着、粘着、溶着等の固定手段によりパウチ内面に固定してもよい。
固定に際して、消臭剤組成物は、パウチ内面のほぼ全体を被覆するように固定してもよいが、少なくとも排泄物等導入孔の近傍（導入孔の周囲及び導入孔に対向する部分）、又は排泄物等排出口の近傍（排出口の周囲及び排出口の上部）を部分的に被覆するように固定することが好ましい。排泄物等導入孔や排泄物等排出口の近傍に消臭剤組成物を固定することにより、消臭剤組成物と排泄物等との接触の機会を増やし、消臭剤組成物が効果的に消費される。
消臭剤組成物の固定の方法は、特に限定されないが、消臭剤組成物を含む溶液、スラリー、エマルション又はディスパーション等を、ストーマ装具のパウチを構成するフィルムに塗工又は噴霧してパウチ内面に膜を形成する方法を例示することができる。
In order to store the deodorant composition for the stoma device of the present invention in the pouch of the stoma device, the deodorant composition may be simply put in the pouch, or the deodorant composition is adhered and adhered. Alternatively, the inner surface of the pouch may be fixed by fixing means such as welding.
At the time of fixing, the deodorant composition may be fixed so as to cover almost the entire inner surface of the pouch, but at least in the vicinity of the introduction hole such as excrement (a part around the introduction hole and the part facing the introduction hole), or It is preferable to fix so that the vicinity of the excretion discharge port (the periphery of the discharge port and the upper part of the discharge port) may be partially covered. By fixing the deodorant composition in the vicinity of the excrement introduction hole and the excrement discharge port, the chance of contact between the deodorant composition and the excrement is increased, and the deodorant composition is effective. Is consumed.
The fixing method of the deodorant composition is not particularly limited, but a solution, slurry, emulsion or dispersion containing the deodorant composition is applied to or sprayed on the film constituting the pouch of the stoma device. A method for forming a film on the inner surface can be exemplified.
ストーマ装具の基本的な構成は、体表面のストーマの周囲に粘着固定する面板と、ストーマから排出される排泄物等を収容するパウチとから構成され、面板及びパウチには、排泄物等をパウチに受け入れるための孔が連通した状態で設けられる。ストーマ装具の種類としては、面板とパウチとが着脱可能になっているツーピースタイプ（二品型装具）のもの及び面板とパウチとが一体になっているワンピースタイプ（一品型装具）のもののどちらも利用できる。また、パウチは、パウチの下部に排泄物等の排出口を備えるドレインパウチ（下部開放型）であっても、そのような排出口を持たないクローズパウチ（下部閉鎖型）であってもよい。 The basic configuration of the stoma device is composed of a face plate that is adhesively fixed around the stoma on the body surface and a pouch that contains excreta discharged from the stoma. The face plate and the pouch are made of pouch. A hole for receiving is provided in communication. The types of stoma devices are either two-piece type (two-piece type equipment) in which the face plate and pouch are removable, or one-piece type (one-piece type equipment) in which the face plate and pouch are integrated. Available. Further, the pouch may be a drain pouch (lower open type) having a discharge port for excrement or the like at the lower part of the pouch, or a closed pouch without such a discharge port (lower closed type).
ストーマ装具を構成する面板は、編布や不織布等の布帛、フィルム、発泡シート等からなる支持層の片面に、粘着層を設けた従来公知のものでよく、粘着層としては、水を吸着又は吸収する親水性物質を含有させた公知のハイドロコロイド粘着剤を使用することができる。
パウチの形状は、フィルムの外周縁をシールして形成される、略円形、楕円形等の従来からのものであってよい。パウチを構成するフィルム材料としては、ポリオレフィン、ポリオレフィン共重合体、ポリ塩化ビニル、ポリ塩化ビニリデン、ポリアミド、ポリエステル等の合成樹脂フィルムを挙げることができる。これらの材料は、単一で使用してもよく、二種類以上を混合して使用してもよい。フィルムは単層であっても、複数枚を積層させた複合フィルムであってもよい。
The face plate constituting the stoma device may be a conventionally known one in which an adhesive layer is provided on one side of a support layer made of a fabric such as a knitted fabric or a nonwoven fabric, a film, a foamed sheet, etc. A known hydrocolloid pressure-sensitive adhesive containing a hydrophilic substance to be absorbed can be used.
The pouch may have a conventional shape such as a substantially circular shape or an elliptical shape formed by sealing the outer peripheral edge of the film. Examples of the film material constituting the pouch include synthetic resin films such as polyolefin, polyolefin copolymer, polyvinyl chloride, polyvinylidene chloride, polyamide, and polyester. These materials may be used alone or in combination of two or more. The film may be a single layer or a composite film in which a plurality of films are laminated.
以下、本発明を実施例に基づいて更に詳細に説明する。なお、本実施例中、部及び％は、特に言及がない限り、重量基準である。
また、消臭剤組成物の特性評価は、以下に示す方法に従って実施した。
Hereinafter, the present invention will be described in more detail based on examples. In the examples, parts and% are based on weight unless otherwise specified.
Moreover, the characteristic evaluation of the deodorant composition was implemented in accordance with the method shown below.
［ポリフェノール含有量］
次の手順により総ポリフェノール量を求め、これを消臭剤組成物中のポリフェノール含有量とする。
（１）消臭剤組成物の濃度が２ｍｇ／ｍｌ水溶液となるように、消臭剤組成物水溶液を調整する。
（２）試験管にサンプル水溶液１００μｌを入れ、蒸留水７．５ｍｌを加える。
（３）０．９Ｎフェノール試液３００μｌを加え、試験管ミキサーで撹拌する。
（４）２０％炭酸ナトリウム水溶液を１ｍｌを加え、更に蒸留水で１０ｍｌにメスアップし、試験管ミキサーで撹拌し、１時間静置する。
（５）分光光度計により７６５ｎｍの波長における吸光度を測定する。
（６）クロロゲン酸水溶液から作成した検量線（０、０．１、０．２、０．５、１．０、２．０ｍｇ／ｍｌの各濃度の７６５ｎｍの吸光度を測定（各点３回以上）して作成）を用いて定量し、下式により、クロロゲン酸換算ポリフェノール量を算出する。
ポリフェノール含量（％）
＝［｛クロロゲン酸量（ｍｇ／ｍｌ）｝／｛２（ｍｇ／ｍｌ）｝］×１００
[Polyphenol content]
The total amount of polyphenol is obtained by the following procedure, and this is defined as the content of polyphenol in the deodorant composition.
(1) Adjust the deodorant composition aqueous solution so that the concentration of the deodorant composition is 2 mg / ml aqueous solution.
(2) Put 100 μl of the sample aqueous solution into a test tube and add 7.5 ml of distilled water.
(3) Add 300 μl of 0.9N phenol test solution and stir with a test tube mixer.
(4) Add 1 ml of 20% aqueous sodium carbonate solution, and further make up to 10 ml with distilled water, stir with a test tube mixer and let stand for 1 hour.
(5) The absorbance at a wavelength of 765 nm is measured with a spectrophotometer.
(6) A calibration curve prepared from an aqueous solution of chlorogenic acid (absorbance at 765 nm at each concentration of 0, 0.1, 0.2, 0.5, 1.0, 2.0 mg / ml was measured (at least 3 times each point) The amount of polyphenol converted to chlorogenic acid is calculated by the following formula.
Polyphenol content (%)
= [{Chlorogenic acid amount (mg / ml)} / {2 (mg / ml)}] × 100
［粉体状消臭剤組成物の粉体の頻度分布］
レーザー回析／散乱式粒度分布測定装置（堀場製作所社製、商品名「ＨＯＬＩＢＡ ＬＡ−９１０」）を使用して求める。また、本装置を使用し、粉体状消臭剤組成物の平均粒径（単位：μｍ）を求める。
[Frequency distribution of powder of powdery deodorant composition]
This is determined using a laser diffraction / scattering type particle size distribution measuring apparatus (trade name “HOLIBA LA-910” manufactured by Horiba, Ltd.). Moreover, the average particle diameter (unit: micrometer) of a powdery deodorant composition is calculated | required using this apparatus.
［ＤＰＰＨラジカル消去能］
ラジカル消去能の指標として、代表的な抗酸化物質であるα-トコフェロールの側鎖をはずした「Ｔｒｏｌｏｘ」を用い、１μｍｏｌのＴｒｏｌｏｘに相当するＤＰＰＨラジカル消去能を「１ＤＰＰＨ単位」として表し、消臭剤組成物の抗酸化能をＤＰＰＨ単位で評価する。値が高いほど、消臭性が良好となる。
（１）検量線の作成
（ｉ）ＤＰＰＨ（ＣＡＳ：１８９８−６６−４）の１ｍＭエタノール溶液を調整する。
（ｉｉ）Ｔｒｏｌｏｘ（ＣＡＳ：５３１８８−０７−１）６４．５ｍｇをエタノール溶液で１００ｍｌにメスアップする。
（ｉｉｉ）(ｉｉ)で調製した溶液を希釈して０．１、０．２、０．３、０．４（μｍｏｌ/４ｍｌ）の溶液をそれぞれ調製し、各濃度のＴｒｏｌｏｘ溶液を４ｍｌずつ試験管にとる。コントロールとして、Ｔｒｏｌｏｘ濃度０にあたるエタノール４ｍｌも試験管にとる。
（ｉｖ）ＤＰＰＨ溶液１ｍｌを各試験管に加え、試験管ミキサーで撹拌し、３０分間静置する。
（ｖ）分光光度計により５２０ｎｍの波長の吸光度を測定し、Ｔｒｏｌｏｘ濃度に対する吸光度の検量線を作成する。Ｔｒｏｌｏｘの量の数値は、そのまま「ＤＰＰＨ単位」として扱う。
[DPPH radical scavenging ability]
As an index of radical scavenging ability, “Trolox” from which the side chain of α-tocopherol, which is a typical antioxidant, is removed, and the DPPH radical scavenging ability corresponding to 1 μmol of Trolox is expressed as “1DPPH unit”. The antioxidant capacity of the agent composition is evaluated in DPPH units. The higher the value, the better the deodorant property.
(1) Preparation of calibration curve (i) A 1 mM ethanol solution of DPPH (CAS: 1898-66-4) is prepared.
(Ii) 64.5 mg of Trolox (CAS: 53188-07-1) is made up to 100 ml with an ethanol solution.
(Iii) Dilute the solution prepared in (ii) to prepare 0.1, 0.2, 0.3, and 0.4 (μmol / 4ml) solutions, respectively, and test 4 ml of each concentration of Trolox solution. Take to tube. As a control, 4 ml of ethanol having a Trolox concentration of 0 is also taken into a test tube.
(Iv) 1 ml of DPPH solution is added to each test tube, stirred with a test tube mixer, and allowed to stand for 30 minutes.
(V) The absorbance at a wavelength of 520 nm is measured with a spectrophotometer, and a calibration curve of absorbance with respect to the Trolox concentration is prepared. The numerical value of the amount of Trolox is handled as “DPPH unit” as it is.
（２）ＤＰＰＨラジカル消去能の評価
（ｉ）消臭剤組成物の濃度が０．５ｍｇ／ｍｌ溶液となるように、５０％エタノール溶液で調整する。
（ｉｉ）試験管に（ｉ）の溶液４ｍｌにＤＰＰＨ溶液１ｍｌを加えたものを採取し、試験管ミキサーで撹拌し、３０分間静置する。また、ブランクとして、（ｉ）の溶液４ｍｌにエタノール１ｍｌを加えたものを試験管に採取する。
(ｉｉｉ)分光光度計により５２０ｎｍの波長の吸光度を測定し、作成した検量線から消臭剤組成物のＤＰＰＨ単位を算出する。
(2) Evaluation of DPPH radical scavenging ability (i) Adjust with a 50% ethanol solution so that the concentration of the deodorant composition is 0.5 mg / ml solution.
(Ii) A test tube obtained by adding 1 ml of DPPH solution to 4 ml of the solution of (i) is collected, stirred with a test tube mixer, and allowed to stand for 30 minutes. Moreover, what added 1 ml of ethanol to 4 ml of the solution of (i) as a blank is extract | collected to a test tube.
(iii) The absorbance at a wavelength of 520 nm is measured with a spectrophotometer, and the DPPH unit of the deodorant composition is calculated from the prepared calibration curve.
［生理食塩水への溶解度］
２０℃、５ｍｌの生理食塩水（０．９％塩化ナトリウム水溶液）中に消臭剤組成物を加えて攪拌し、生理食塩水に溶解した消臭剤組成物量の割合を、下式により算出する。消臭剤組成物の溶解の判断は、消臭剤組成物を生理食塩水に徐々に加えていき、未溶解の消臭剤組成物残渣の有無を目視確認することにより行なう。
溶解度（％）＝（溶解した消臭剤組成物量／生理食塩水５ｇ）×１００
[Solubility in physiological saline]
Deodorant composition is added and stirred in 5 ml of physiological saline (0.9% sodium chloride aqueous solution) at 20 ° C., and the ratio of the amount of deodorant composition dissolved in physiological saline is calculated by the following formula. . The determination of dissolution of the deodorant composition is performed by gradually adding the deodorant composition to physiological saline and visually confirming the presence or absence of an undissolved deodorant composition residue.
Solubility (%) = (Amount of deodorant composition dissolved / 5 g of physiological saline) × 100
［生理食塩水への溶解後の粘度］
消臭剤組成物の濃度を、生理食塩水（０．９％塩化ナトリウム水溶液）で、０．２ｇ／ｍｌ溶液となるように調整し、ＢＨ型粘度計を用いて、次の条件で測定した値を粘度とする。測定条件：ローターＮｏ．２、回転数２０ｒｐｍ、回転時間１分、溶液温度２０℃（なお、粘度が低く、ローターＮｏ．２で測定できない場合は、ローターＮｏ．１を使用する）。
[Viscosity after dissolution in physiological saline]
The concentration of the deodorant composition was adjusted with physiological saline (0.9% sodium chloride aqueous solution) to a 0.2 g / ml solution, and measured using a BH viscometer under the following conditions. The value is the viscosity. Measurement conditions: rotor no. 2, rotation speed 20 rpm,
［生理食塩水への溶解後の拡散面積］
消臭剤組成物の濃度を、生理食塩水（０．９％塩化ナトリウム水溶液）で、０．２ｇ／ｍｌ溶液となるように調整し、この溶液２ｍｌを、プラスチックシャーレの表面５ｃｍ上から滴下する。シャーレ表面に広がった溶液の一定方向の最大長さと、その方向に直交する方向の最大長さとの積を求め、測定５回の平均値を拡散面積（ｃｍ２）とする。
[Diffusion area after dissolution in physiological saline]
The concentration of the deodorant composition is adjusted with physiological saline (0.9% sodium chloride aqueous solution) to a 0.2 g / ml solution, and 2 ml of this solution is dropped from 5 cm above the surface of the plastic petri dish. . The product of the maximum length in a certain direction of the solution spread on the petri dish surface and the maximum length in the direction orthogonal to that direction is obtained, and the average value of five measurements is defined as the diffusion area (cm 2 ).
［フィルムへの付着率］
１０ｃｍ×１０ｃｍの正方形にカットしたポリエチレンフィルム（タマポリ社製、品番Ｍ−００１、厚さ６０μｍ）の上に０．５ｇの消臭剤組成物を置き、約２５ｃｍ２に広げる（図１参照）。このフィルムの頂点の１つをピンセットで垂直に取り上げ、ピンセットの垂直状態の位置を基準に左右に約１５°ずつ、合計１０回軽く揺らし、余分な消臭剤組成物を落下させる（図２参照）。
その後、フィルムに付着した消臭剤組成物の重量を測定し、フィルムへの付着率を以下の式により算出し、測定５回の平均値をフィルムへの付着率（％）とする。これらの測定は、２０℃、相対湿度２０％の室内で行なう。
フィルムへの付着率（％）
＝｛（フィルムに付着した消臭剤組成物の重量ｇ）/０．５ｇ｝×１００
[Adhesion rate to film]
A deodorant composition of 0.5 g is placed on a polyethylene film (manufactured by Tamapoly, product number M-001, thickness 60 μm) cut into a 10 cm × 10 cm square and spread to about 25 cm 2 (see FIG. 1). One of the apexes of this film is picked up vertically with tweezers and gently shaken 10 times a total of about 15 ° to the left and right with respect to the position of the tweezers in the vertical direction to drop the excess deodorant composition (see FIG. 2). ).
Then, the weight of the deodorant composition adhering to the film is measured, the adhesion rate to the film is calculated by the following formula, and the average value of five measurements is defined as the adhesion rate (%) to the film. These measurements are performed in a room at 20 ° C. and a relative humidity of 20%.
Adhesion rate to film (%)
= {(Weight g of deodorant composition adhering to film) /0.5 g} × 100
［メチルメルカプタン消臭率］
フラスコに消臭剤組成物を約１．５ｇ投入し、次いで、約５０ｇの人便を投入し密閉する。フラスコを、被服内環境を想定した３２℃恒温槽中に静置する。３０分後に、ガス検知管によりメチルメルカプタン濃度を測定し、次式により消臭率（％）を算出する。
消臭率（％）
＝１００−（消臭剤組成物添加３０分後のガス濃度／消臭剤組成物添加前のガス濃度）×１００
[Methyl mercaptan deodorization rate]
About 1.5 g of the deodorant composition is charged into the flask, and then about 50 g of human stool is charged and sealed. The flask is allowed to stand in a constant temperature bath of 32 ° C. assuming the environment in the clothes. After 30 minutes, the methyl mercaptan concentration is measured with a gas detector tube, and the deodorization rate (%) is calculated by the following equation.
Deodorization rate (%)
= 100- (gas concentration 30 minutes after addition of deodorant composition / gas concentration before addition of deodorant composition) × 100
［消臭性官能評価］
ストーマ装具のパウチに消臭剤組成物を約１．５ｇ投入し、次いで、約５０ｇの人便を投入する。ストーマ装具のパウチの排泄物排出口をクリップ（排出口留め具）で封止し、被服内環境を想定した３２℃恒温槽中に静置する。３時間後に、人便をパウチから取り出した時に感じる臭気を、６段階臭気強度表示法及び９段階快・不快表示法に示す基準により、それぞれ、評価する。
この評価を３人の評価者が行い、その平均点数を求める。
６段階臭気強度表示法による評価では、平均点数が小さいほど、９段階快・不快表示法による評価では、平均点数が大きいほど、消臭性が優れている。
[Deodorant sensory evaluation]
About 1.5 g of the deodorant composition is introduced into the pouch of the stoma appliance, and then about 50 g of human stool is introduced. The excrement discharge port of the pouch of the stoma device is sealed with a clip (discharge port fastener), and the pouch is left in a constant temperature bath assuming a clothing environment. After 3 hours, the odor felt when the human stool is removed from the pouch is evaluated according to the criteria shown in the 6-level odor intensity display method and the 9-level pleasant / unpleasant display method.
Three evaluators perform this evaluation, and the average score is obtained.
In the evaluation by the 6-step odor intensity display method, the smaller the average score, the better the deodorization property in the evaluation by the 9-step pleasant / unpleasant display method, the larger the average score.
（臭気強度表示法による臭気評価）
点数：評価基準
０：無臭
１：やっと感知できるにおい（検知閾値濃度）
２：何のにおいであるかが分かる弱いにおい（認知閾値濃度）
３：らくに感知できるにおい（簡単に感知できるにおい）
４：強いにおい
５：強烈なにおい
(Odor evaluation by odor intensity display method)
Score: Evaluation criteria 0: Odorless 1: Scent that can be finally detected (detection threshold concentration)
2: Weak smell that can tell what kind of smell (cognitive threshold concentration)
3: Smell that can be easily detected (scent that can be easily detected)
4: Strong smell 5: Strong smell
（快・不快表示法による臭気評価）
点数：評価基準
−４：極端に不快
−３：非常に不快
−２：不快
−１：やや不快
０：快でも不快でもない
＋１：やや快
＋２：快
＋３：非常に快
＋４：極端に快
(Odor evaluation by pleasant / unpleasant labeling method)
Score: Evaluation criteria -4: Extremely uncomfortable -3: Very uncomfortable -2: Uncomfortable -1: Slightly uncomfortable 0: Not pleasant or uncomfortable +1: Slightly comfortable +2: Comfortable +3: Very pleasant +4: Extremely pleasant
［排泄物等排出所要時間］
ストーマ装具のパウチに消臭剤組成物を約１．５ｇ投入し、次いで、約５０ｇの人便を投入する。パウチの排泄物排出口をクリップ（排出口留め具）で封止し、被服内環境を想定した３２℃恒温槽中に静置する。３時間後に、クリップを取り外し、パウチの排出口を開放する。パウチから人便が自然落下するのに要する時間を測定する。
[Time required for excretion etc.]
About 1.5 g of the deodorant composition is introduced into the pouch of the stoma appliance, and then about 50 g of human stool is introduced. The excrement discharge port of the pouch is sealed with a clip (discharge port fastener) and left in a constant temperature bath of 32 ° C. assuming the environment inside the clothes. After 3 hours, remove the clip and open the pouch outlet. Measure the time it takes for the stool to fall naturally from the pouch.
［ｐＨ］
ＪＩＳ Ｚ８８０２に準拠して、校正したｐＨ計電極を洗浄後、消臭剤組成物のｐＨを３回測定して平均値を求める。
なお、消臭剤組成物が粉体又は固体である場合は、２０％水溶液として、そのｐＨを測定する。
[PH]
In accordance with JIS Z8802, the calibrated pH meter electrode is washed, and then the pH of the deodorant composition is measured three times to obtain an average value.
When the deodorant composition is powder or solid, the pH is measured as a 20% aqueous solution.
（実施例１）
ペパーミント油、アラビアガム、デキストリン及び水からなる混合物を熱風中に噴霧し、水分を蒸散させて粉体を得た。この粉体は、ペパーミント油がアラビアガムとデキストリンによりマイクロカプセル化されたものである。
この粉体に、コーヒー豆粉砕物の水抽出物を噴射乾燥して得たポリフェノール含有粉体を混合し、表１に示す組成の粉体状の本発明のストーマ装具用消臭剤組成物を得た。
この消臭剤組成物について、その特性を評価した。結果を表１に示す。
Example 1
A mixture consisting of peppermint oil, gum arabic, dextrin and water was sprayed into hot air, and water was evaporated to obtain a powder. This powder is made by microencapsulating peppermint oil with gum arabic and dextrin.
This powder is mixed with a polyphenol-containing powder obtained by spray-drying an aqueous extract of ground coffee beans, and the powdered deodorant composition for stoma appliances of the present invention having the composition shown in Table 1 is mixed. Obtained.
The deodorant composition was evaluated for its characteristics. The results are shown in Table 1.
（実施例２〜３）
消臭剤組成物の組成を表１に示すように変える以外は実施例１と同様の方法で粉体状の消臭剤組成物を得た。この消臭剤組成物について、その特性を評価した。結果を表１に示す。
(Examples 2-3)
A powdery deodorant composition was obtained in the same manner as in Example 1 except that the composition of the deodorant composition was changed as shown in Table 1. The deodorant composition was evaluated for its characteristics. The results are shown in Table 1.
（実施例４〜６）
ポリフェノール含有粉体を、りんご、ぶどう及び緑茶からの水抽出物にそれぞれ変える以外は、実施例１と同様の方法で粉体状の消臭剤組成物を得た。この消臭剤組成物について、その特性を評価した。結果を表１に示す。
(Examples 4 to 6)
A powdery deodorant composition was obtained in the same manner as in Example 1 except that the polyphenol-containing powder was changed to water extracts from apples, grapes and green tea. The deodorant composition was evaluated for its characteristics. The results are shown in Table 1.
（実施例７）
実施例１と同様の方法で得た粉体状の消臭剤組成物に、精製水を加え均一に混合して、表２に示す組成の液状の消臭剤組成物を得た。
この消臭剤組成物について、その特性を評価した。結果を表２に示す。
(Example 7)
Purified water was added to the powdery deodorant composition obtained by the same method as in Example 1 and mixed uniformly to obtain a liquid deodorant composition having the composition shown in Table 2.
The deodorant composition was evaluated for its characteristics. The results are shown in Table 2.
（実施例８〜９）
実施例１と同様の方法で得た粉体状の消臭剤組成物、精製水、プルラン及びパルプを均一に混合し、得られた混合物を剥離シート上に塗工乾燥して、表２に示す組成のシート状の消臭剤組成物を得た（実施例８）。また、同様に、表２に示す組成を有する、実施例８と同様の方法で得たシート状の消臭剤組成物の外周縁を接合し、袋状の消臭剤組成物を得た（実施例９）。
これらの消臭剤組成物について、その特性を評価した。結果を表２に示す。
(Examples 8 to 9)
The powdery deodorant composition, purified water, pullulan and pulp obtained in the same manner as in Example 1 were uniformly mixed, and the resulting mixture was applied and dried on a release sheet, and Table 2 A sheet-like deodorant composition having the composition shown was obtained (Example 8). Similarly, the outer peripheral edge of the sheet-like deodorant composition obtained in the same manner as in Example 8 having the composition shown in Table 2 was joined to obtain a bag-like deodorant composition ( Example 9).
The properties of these deodorant compositions were evaluated. The results are shown in Table 2.
（比較例１）
ポリエチレングリコール、ゼオライト及びトウモロコシデンプンの混合物からなる粉体状の消臭剤組成物を調製した。
この消臭剤組成物について、その特性を評価した。結果を表２に示す。
(Comparative Example 1)
A powdery deodorant composition comprising a mixture of polyethylene glycol, zeolite and corn starch was prepared.
The deodorant composition was evaluated for its characteristics. The results are shown in Table 2.
（比較例２）
木炭と、カオリナイトから焼成されたセラミックスとを、混合した粉体状の消臭剤組成物を調製した。
この消臭剤組成物について、その特性を評価した。結果を表２に示す。
(Comparative Example 2)
A powdery deodorant composition in which charcoal and ceramics fired from kaolinite were mixed was prepared.
The deodorant composition was evaluated for its characteristics. The results are shown in Table 2.
表１及び表２に示す結果から、ポリフェノールを含有しない消臭剤組成物を用いた場合は、消臭効果は殆ど認められなかった（比較例１及び２）。
これに対して、ポリフェノールを含有し、生理食塩水への溶解度が３０％以上、生理食塩水への溶解後の粘度が７００ｍＰａ・ｓ以下、生理食塩水への溶解後の拡散面積が７．０ｃｍ２以上である本発明のストーマ装具用消臭剤組成物を用いた場合は、優れた消臭効果が得られることが分かる（各実施例）。
これは、本発明のストーマ装具用消臭剤組成物が、比較例で用いた消臭剤組成物に比べてパウチ壁面に広範囲にわたって付着し、更に排泄物の水分に対しても溶解し易く、流動性も高いため、消臭の有効成分を排泄物の多くの部分に作用させることができたためと考えられる。
また、本発明のストーマ装具用消臭剤組成物を用いた場合、排泄物の滑り性も向上しており、排泄物等排出所要時間も少なかった。これは、排泄物中の水分を吸収した消臭剤組成物が速やかに溶解してパウチ内に拡散し、排泄物中の水分を吸収した消臭剤組成物が流動性のある粘度を有していたためと考えられる。
From the results shown in Tables 1 and 2, almost no deodorizing effect was observed when a deodorant composition containing no polyphenol was used (Comparative Examples 1 and 2).
On the other hand, it contains polyphenol, has a solubility in physiological saline of 30% or more, a viscosity after dissolution in physiological saline of 700 mPa · s or less, and a diffusion area after dissolution in physiological saline of 7.0 cm. It can be seen that an excellent deodorizing effect can be obtained when the deodorant composition for a stoma device of the present invention of 2 or more is used (each example).
This is because the deodorant composition for the stoma device of the present invention adheres to the pouch wall surface over a wide range as compared with the deodorant composition used in the comparative example, and more easily dissolves in the water of excrement, It is thought that because the fluidity is high, the deodorant active ingredient was able to act on many parts of the excrement.
Moreover, when the deodorant composition for stoma appliances of this invention was used, the slipperiness of excrement was also improved and excrement discharge | emission required time was also short. This is because the deodorant composition that has absorbed the water in the excrement dissolves quickly and diffuses into the pouch, and the deodorant composition that has absorbed the water in the excrement has a fluid viscosity. It is thought that it was because of.
１ フィルム
２ 消臭剤組成物
３ ピンセット
1
Claims (19)
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006040841A JP5176061B2 (en) | 2006-02-17 | 2006-02-17 | Deodorant composition for stoma device and stoma device |
| PCT/JP2006/312709 WO2007000968A1 (en) | 2005-06-27 | 2006-06-26 | Deodorizer composition for article for treating excretory substances and article for treating excretory substances |
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| JP2006040841A JP5176061B2 (en) | 2006-02-17 | 2006-02-17 | Deodorant composition for stoma device and stoma device |
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| JP2007215831A true JP2007215831A (en) | 2007-08-30 |
| JP2007215831A5 JP2007215831A5 (en) | 2009-04-02 |
| JP5176061B2 JP5176061B2 (en) | 2013-04-03 |
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| JP2010227130A (en) * | 2009-03-25 | 2010-10-14 | Kao Corp | Beta-glucuronidase inhibitor |
| JP2013504698A (en) * | 2009-09-18 | 2013-02-07 | ザ プロクター アンド ギャンブル カンパニー | Freshening composition comprising malodor binding polymer and malodor neutralizer |
| JP2013504697A (en) * | 2009-09-18 | 2013-02-07 | ザ プロクター アンド ギャンブル カンパニー | Freshening composition comprising malodor binding polymer |
| JP2013165849A (en) * | 2012-02-15 | 2013-08-29 | Nof Corp | Lubricant composition for ostomy pouch |
| JP2014226354A (en) * | 2013-05-23 | 2014-12-08 | 株式会社トライ・カンパニー | Deodorization pack for inside of stoma bag |
| JP2016170068A (en) * | 2015-03-13 | 2016-09-23 | 小川香料株式会社 | Deodorizer evaluating method and immediately effective deodorizer |
| JP2018143650A (en) * | 2017-03-08 | 2018-09-20 | パナソニックＩｐマネジメント株式会社 | Lubrication deodorant composition for stoma attachment and stoma attachment kit |
| JP2018176096A (en) * | 2017-04-17 | 2018-11-15 | 株式会社エクセルシア | Excrement treatment agent |
| JP2023014113A (en) * | 2018-10-17 | 2023-01-26 | アルケア株式会社 | Ostomy prosthesis lubricating deodorant composition |
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| KR102660765B1 (en) * | 2022-06-10 | 2024-04-24 | 최기면 | Manufacturing method of an antimicrobial menstrual cup and the menstrual cup manufactured thereby |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2010227130A (en) * | 2009-03-25 | 2010-10-14 | Kao Corp | Beta-glucuronidase inhibitor |
| JP2013504698A (en) * | 2009-09-18 | 2013-02-07 | ザ プロクター アンド ギャンブル カンパニー | Freshening composition comprising malodor binding polymer and malodor neutralizer |
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| US9273427B2 (en) | 2009-09-18 | 2016-03-01 | The Procter & Gamble Company | Freshening compositions comprising malodor binding polymers |
| JP2013165849A (en) * | 2012-02-15 | 2013-08-29 | Nof Corp | Lubricant composition for ostomy pouch |
| JP2014226354A (en) * | 2013-05-23 | 2014-12-08 | 株式会社トライ・カンパニー | Deodorization pack for inside of stoma bag |
| JP2016170068A (en) * | 2015-03-13 | 2016-09-23 | 小川香料株式会社 | Deodorizer evaluating method and immediately effective deodorizer |
| JP2018143650A (en) * | 2017-03-08 | 2018-09-20 | パナソニックＩｐマネジメント株式会社 | Lubrication deodorant composition for stoma attachment and stoma attachment kit |
| JP2018176096A (en) * | 2017-04-17 | 2018-11-15 | 株式会社エクセルシア | Excrement treatment agent |
| JP2023014113A (en) * | 2018-10-17 | 2023-01-26 | アルケア株式会社 | Ostomy prosthesis lubricating deodorant composition |
| JP7455310B2 (en) | 2018-10-17 | 2024-03-26 | アルケア株式会社 | Lubricating deodorant composition for ostomy appliances |
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