JP2023014113A - Ostomy prosthesis lubricating deodorant composition - Google Patents
Ostomy prosthesis lubricating deodorant composition Download PDFInfo
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- JP2023014113A JP2023014113A JP2022177870A JP2022177870A JP2023014113A JP 2023014113 A JP2023014113 A JP 2023014113A JP 2022177870 A JP2022177870 A JP 2022177870A JP 2022177870 A JP2022177870 A JP 2022177870A JP 2023014113 A JP2023014113 A JP 2023014113A
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- Prior art keywords
- component
- deodorant
- lubricating
- deodorant composition
- mass
- Prior art date
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- 238000002386 leaching Methods 0.000 description 1
- 239000004571 lime Substances 0.000 description 1
- 239000000395 magnesium oxide Substances 0.000 description 1
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- BMMGVYCKOGBVEV-UHFFFAOYSA-N oxo(oxoceriooxy)cerium Chemical compound [Ce]=O.O=[Ce]=O BMMGVYCKOGBVEV-UHFFFAOYSA-N 0.000 description 1
- 239000003002 pH adjusting agent Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
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- 229920001495 poly(sodium acrylate) polymer Polymers 0.000 description 1
- 229920002432 poly(vinyl methyl ether) polymer Polymers 0.000 description 1
- 229920002401 polyacrylamide Polymers 0.000 description 1
- 229920000058 polyacrylate Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
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- 235000013824 polyphenols Nutrition 0.000 description 1
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- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
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- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 229920001592 potato starch Polymers 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
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- 239000000770 propane-1,2-diol alginate Substances 0.000 description 1
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- 235000009566 rice Nutrition 0.000 description 1
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- 239000011734 sodium Substances 0.000 description 1
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- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
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- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- 235000002639 sodium chloride Nutrition 0.000 description 1
- NNMHYFLPFNGQFZ-UHFFFAOYSA-M sodium polyacrylate Chemical compound [Na+].[O-]C(=O)C=C NNMHYFLPFNGQFZ-UHFFFAOYSA-M 0.000 description 1
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- IPMYMEWFZKHGAX-ZKSIBHASSA-N theaflavin Chemical compound C1=C2C([C@H]3OC4=CC(O)=CC(O)=C4C[C@H]3O)=CC(O)=C(O)C2=C(O)C(=O)C=C1[C@@H]1[C@H](O)CC2=C(O)C=C(O)C=C2O1 IPMYMEWFZKHGAX-ZKSIBHASSA-N 0.000 description 1
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- 230000008719 thickening Effects 0.000 description 1
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- UJMBCXLDXJUMFB-UHFFFAOYSA-K trisodium;5-oxo-1-(4-sulfonatophenyl)-4-[(4-sulfonatophenyl)diazenyl]-4h-pyrazole-3-carboxylate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)C1=NN(C=2C=CC(=CC=2)S([O-])(=O)=O)C(=O)C1N=NC1=CC=C(S([O-])(=O)=O)C=C1 UJMBCXLDXJUMFB-UHFFFAOYSA-K 0.000 description 1
- 235000013799 ultramarine blue Nutrition 0.000 description 1
- 230000002485 urinary effect Effects 0.000 description 1
- 210000001635 urinary tract Anatomy 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
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- 210000000051 wattle Anatomy 0.000 description 1
- 229940100445 wheat starch Drugs 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- 239000011787 zinc oxide Substances 0.000 description 1
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 1
Landscapes
- Orthopedics, Nursing, And Contraception (AREA)
- Materials For Medical Uses (AREA)
- Disinfection, Sterilisation Or Deodorisation Of Air (AREA)
- Lubricants (AREA)
Abstract
Description
本発明は、オストミー装具用の潤滑消臭剤組成物に関する。 The present invention relates to lubricating deodorant compositions for ostomy appliances.
消化器、泌尿器等の疾患がある場合や、排泄を自らの意思で制御できない場合に、消化管や尿路を体表まで導き体表面にストーマ(人工肛門、人工膀胱等)を造設することがある。ストーマは排泄を自己制御できないため、ストーマからの排泄物等を一時的に貯留するための袋(オストミー装具)をストーマ開口部に装着することが行われている。オストミー装具を使用する際の問題点として、特にオストミー装具から排泄物等を取り出す際に、排泄物等の臭気が拡散してしまうという問題があった。 To guide the digestive tract and urinary tract to the body surface and construct a stoma (artificial anus, artificial bladder, etc.) on the body surface when there is a disease of the digestive system, urinary system, etc., or when excretion cannot be controlled by one's own will. There is Since the stoma cannot self-regulate excretion, a bag (ostomy appliance) for temporarily storing excretion from the stoma is attached to the opening of the stoma. As a problem in using the ostomy appliance, there is a problem that the odor of the excrement diffuses especially when the excrement is removed from the ostomy appliance.
これまでに、排泄物等の臭気を除去するための様々な消臭剤が提案されている。例えば、特許文献1には、ポリフェノールを含有することを特徴とするストーマ装具用消臭剤組成物が開示されている。また、特許文献2には、a)柿渋タンニン、b)非イオン性セルロース系水溶性ポリマーおよび陰イオン性セルロース系水溶性ポリマーからなる群より選択される1種または2種以上、ならびにc)炭酸塩および炭酸水素塩からなる群より選択される1種または2種以上を、d)水に含有させてなる、オストミーパウチ用潤滑剤組成物が開示されている。さらに、特許文献3には、さとうきび由来の糖蜜類である糖蜜および/または糖蜜アルコール発酵蒸留残渣および/または黒糖アルコール発酵蒸留残渣より得られる分子量2万以下の消臭作用を有することを特徴とする糖蜜分画物が開示されている。また、特許文献4には、水溶性潤滑剤および糞便物の発臭分子と錯体形成してそれを中和することが可能な相溶性水溶性錯化剤の両方を含有する水溶液を含む、オストミーパウチ用潤滑消臭剤が開示されている。 Various deodorants have been proposed so far for removing odors such as excrement. For example, Patent Document 1 discloses a deodorant composition for an ostomy appliance, which is characterized by containing polyphenol. In addition, Patent Document 2 discloses a) persimmon tannin, b) one or more selected from the group consisting of nonionic cellulose-based water-soluble polymers and anionic cellulose-based water-soluble polymers, and c) carbonic acid. Disclosed is a lubricant composition for ostomy pouches, comprising d) water containing one or more selected from the group consisting of salts and bicarbonates. Furthermore, in Patent Document 3, it is characterized by having a deodorant effect with a molecular weight of 20,000 or less obtained from molasses, which is sugar cane-derived molasses, and/or molasses alcohol fermentation and distillation residue and/or brown sugar alcohol fermentation and distillation residue. A molasses fraction is disclosed. Also, US Pat. No. 5,300,002 discloses an ostomy system comprising an aqueous solution containing both a water-soluble lubricant and a compatible water-soluble complexing agent capable of complexing and neutralizing fecal odorant molecules. A lubricating deodorant for pouches is disclosed.
さらに、オストミー装具内の排泄物等を取り出し易くする潤滑剤として、例えば、特許文献5には、鉱油、植物油、動物油及び合成油からなる群から選ばれた1種以上を含有し、水分が90重量%以下であり且つ25℃における粘度が30mPa・s以下であるストーマ装具用潤滑剤組成物が開示されている。 Furthermore, as a lubricant that facilitates removal of excrement from the ostomy appliance, for example, Patent Document 5 discloses a lubricant containing one or more selected from the group consisting of mineral oil, vegetable oil, animal oil, and synthetic oil, and having a water content of 90%. % by weight or less and a viscosity at 25° C. of 30 mPa·s or less is disclosed.
しかしながら、オストミー装具用の潤滑消臭剤は依然として消臭性や取扱性等の性能においてさらなる改良が求められている。そこで、本発明は、性能をさらに改良したオストミー装具用潤滑消臭剤組成物を提供することを目的とする。 However, lubricating deodorants for ostomy appliances are still required to be further improved in performance such as deodorant properties and handleability. Accordingly, an object of the present invention is to provide a lubricating deodorant composition for ostomy appliances with further improved performance.
本発明者らは上記実情に鑑み、潤滑消臭剤の構成成分について鋭意検討を行ったところ、特定の消臭成分を組み合わせ、さらに親水性高分子化合物と水とを含有させることで上記課題を解決できることを見出し、本発明を完成させるに至った。 In view of the above-mentioned circumstances, the present inventors have made extensive studies on the constituent components of lubricating deodorants, and have found that the above problems can be solved by combining specific deodorizing components and further containing a hydrophilic polymer compound and water. We have found that the problem can be solved, and have completed the present invention.
すなわち、本発明は、次の成分(A1)、(B1)、(C)及び(D)を含有し、15~25℃における粘度が800~1,800mPa・sである、オストミー装具用潤滑消臭剤組成物を提供する。
(A1)柿抽出物
(B1)サトウキビ抽出物
(C)カルボキシメチルセルロース
(D)水
また、本発明は、次の成分(A1)、(B1)、(C)及び(D)を含有し、炭酸塩及び炭酸水素塩を含有しない、オストミー装具用潤滑消臭剤組成物も提供する。
(A1)柿抽出物
(B1)サトウキビ抽出物
(C)親水性高分子化合物
(D)水
That is, the present invention contains the following components (A1), (B1), (C) and (D), and has a viscosity of 800 to 1,800 mPa·s at 15 to 25°C. An odorant composition is provided.
(A1) persimmon extract (B1) sugarcane extract (C) carboxymethylcellulose (D) water Also provided is a lubricating deodorant composition for ostomy appliances that is free of salt and bicarbonate.
(A1) persimmon extract (B1) sugar cane extract (C) hydrophilic polymer compound (D) water
また、本発明は、次の成分(A2)、(B2)、(C)及び(D)を含有し、15~25℃における粘度が800~1,800mPa・sである、オストミー装具用潤滑消臭剤組成物も提供する。
(A2)タンニン系化合物を含む消臭成分
(B2)スチルベン系化合物を含む消臭成分
(C)カルボキシメチルセルロース
(D)水
また、本発明は、次の成分(A2)、(B2)、(C)及び(D)を含有し、炭酸塩及び炭酸水素塩を含有しない、オストミー装具用潤滑消臭剤組成物も提供する。
(A2)タンニン系化合物を含む消臭成分
(B2)スチルベン系化合物を含む消臭成分
(C)親水性高分子化合物
(D)水
The present invention also provides a lubricant for ostomy appliances containing the following components (A2), (B2), (C) and (D) and having a viscosity of 800 to 1,800 mPa·s at 15 to 25°C. An odorant composition is also provided.
(A2) Deodorizing component containing tannin compound (B2) Deodorizing component containing stilbene compound (C) Carboxymethyl cellulose (D) Water In addition, the present invention includes the following components (A2), (B2), (C) ) and (D), and is free of carbonates and bicarbonates, is also provided.
(A2) Deodorant component containing tannin compound (B2) Deodorant component containing stilbene compound (C) Hydrophilic polymer compound (D) Water
本発明によれば、消臭性及び取扱性に優れたオストミー装具用潤滑消臭剤組成物を提供することができる。 ADVANTAGE OF THE INVENTION According to this invention, the lubricating deodorant composition for ostomy appliances excellent in deodorant property and handleability can be provided.
以下、本発明を実施するための好適な実施形態について説明する。なお、以下に説明する実施形態は、本発明の代表的な実施形態を示したものであり、これにより本発明の範囲が狭く限定されることはない。 Preferred embodiments for carrying out the present invention are described below. It should be noted that the embodiments described below are representative embodiments of the present invention, and the scope of the present invention is not narrowly limited thereby.
<第1実施形態>
本発明に係る第1実施形態のオストミー装具用潤滑消臭剤組成物(以下、単に「潤滑消臭剤組成物」という)は、成分(A1)柿抽出物、成分(B1)サトウキビ抽出物、成分(C)親水性高分子化合物及び成分(D)水を含有する。以下、各成分について詳細に説明する。
<First embodiment>
The lubricating deodorant composition for an ostomy appliance according to the first embodiment of the present invention (hereinafter simply referred to as "lubricant deodorant composition") comprises component (A1) persimmon extract, component (B1) sugarcane extract, It contains component (C) a hydrophilic polymer compound and component (D) water. Each component will be described in detail below.
本実施形態における成分(A1)柿抽出物は、柿抽出物中に含まれるカキタンニン等の消臭成分によって消臭効果を有すると考えられる。
柿抽出物の抽出方法は、上記消臭成分が抽出できる方法であれば特に限定されない。例えば、原料となる柿を粉砕して圧搾した圧搾汁より分画、精製等を行って得られる抽出物を用いることができる。また、柿抽出物を含む市販品として、例えばリリース科学工業株式会社製「パンシル」シリーズ(「パンシルFG-22」、「パンシルCOS-17」等)を用いることができる。
The component (A1) persimmon extract in the present embodiment is considered to have a deodorizing effect due to deodorant components such as persimmon tannins contained in the persimmon extract.
The method for extracting the persimmon extract is not particularly limited as long as it can extract the deodorizing component. For example, it is possible to use an extract obtained by fractionating, purifying, or the like from the squeezed juice obtained by pulverizing and squeezing persimmon as a raw material. In addition, as a commercial product containing a persimmon extract, for example, the “Pancil” series (“Pancil FG-22”, “Pancil COS-17”, etc.) manufactured by Release Science Industry Co., Ltd. can be used.
本実施形態における成分(A1)柿抽出物は、オストミー装具の使用における消臭性と取扱性(便排出時の潤滑性)の観点で、潤滑消臭剤組成物中に2.5~10質量%の範囲で含有されていることが好ましく、3~8質量%含有されていることがより好ましい。 The component (A1) persimmon extract in the present embodiment is 2.5 to 10 masses in the lubricating deodorant composition from the viewpoint of deodorant and handleability (lubricity during fecal discharge) when using an ostomy appliance. %, more preferably 3 to 8% by mass.
一方、本実施形態における成分(B1)サトウキビ抽出物は、サトウキビ抽出物中に含まれるスチルベン誘導体等の消臭成分によって消臭効果を有すると考えられる。
サトウキビ抽出物の抽出方法は、上記消臭成分が抽出できる方法であれば特に限定されない。例えば、サトウキビ汁又はサトウキビの溶媒抽出物を蒸留して得られる蒸留物より分画、精製等を行って得られる抽出物を用いることができる。上記サトウキビ汁の具体例としては、原料となるサトウキビを圧搾した圧搾汁、サトウキビを水で浸出して得られる浸出汁、又は原糖製造工場において石灰処理した清浄汁及び濃縮汁等が挙げられる。一方、サトウキビの溶媒抽出物の具体例としては、サトウキビをメタノール、エタノール等の
汎用の有機溶媒で抽出した抽出液が挙げられる。また、サトウキビ抽出物を含む市販品として、例えば三井製糖株式会社製「MSX-245」、「MSX-201」等を用いることができる。
On the other hand, the component (B1) sugarcane extract in the present embodiment is considered to have a deodorant effect due to the deodorizing components such as stilbene derivatives contained in the sugarcane extract.
The method for extracting the sugarcane extract is not particularly limited as long as it is a method capable of extracting the deodorizing component. For example, an extract obtained by fractionation, purification, etc. from a distillate obtained by distilling sugarcane juice or a solvent extract of sugarcane can be used. Specific examples of the sugarcane juice include pressed juice obtained by squeezing sugarcane as a raw material, infused juice obtained by leaching sugarcane with water, and clean juice and concentrated juice obtained by lime treatment at a raw sugar manufacturing factory. On the other hand, a specific example of the solvent extract of sugarcane is an extract obtained by extracting sugarcane with a general-purpose organic solvent such as methanol or ethanol. In addition, commercially available products containing sugar cane extracts such as “MSX-245” and “MSX-201” manufactured by Mitsui Sugar Co., Ltd. can be used.
本実施形態における成分(B1)サトウキビ抽出物は、オストミー装具の使用における消臭性と取扱性(便排出時の潤滑性)の観点で、潤滑消臭剤組成物中に0.05~10質量%の範囲で含有されていることが好ましく、0.1~5質量%含有されていることがより好ましい。 The component (B1) sugarcane extract in the present embodiment is 0.05 to 10% by mass in the lubricating deodorant composition from the viewpoint of deodorant and handleability (lubricity during fecal discharge) when using an ostomy appliance. %, more preferably 0.1 to 5% by mass.
本実施形態に係る潤滑消臭剤組成物は、成分(A1)柿抽出物と成分(B1)サトウキビ抽出物とを組み合わせることによって、オストミー装具の使用における消臭性と取扱性(便排出時の潤滑性)を向上させることができる。
本実施形態に係る潤滑消臭剤組成物の消臭機構としては、化学的消臭機構及び感覚的消臭機構が考えられる。化学的消臭機構とは、排泄物等の悪臭成分を不揮発性化、中和、酸化・還元又は分解することによって、消臭を行う機構である。一方、感覚的消臭機構とは、消臭成分の香気によって排泄物等の悪臭を目立たなくして、消臭を行う機構である。後述の実施例に示すとおり、本実施形態に係る潤滑消臭剤組成物は、成分(A1)柿抽出物のみ又は成分(B1)サトウキビ抽出物のみを含有する潤滑消臭剤組成物(比較例1及び2)に比べて、排泄物等の悪臭成分(硫化水素ガス)を分解等する効果にも優れており、さらに排泄物等の臭いを感じにくくする効果にも優れている。このように、本実施形態に係る潤滑消臭剤組成物は、成分(A1)柿抽出物と成分(B1)サトウキビ抽出物とを組み合わせることによって、化学的消臭機構及び感覚的消臭機構による消臭効果を発揮し、排泄物等に対する消臭性が向上していると考えられる。
The lubricating deodorant composition according to the present embodiment combines the component (A1) persimmon extract and the component (B1) sugarcane extract to achieve deodorizing properties and handleability (when stool is discharged) when using an ostomy appliance. lubricity) can be improved.
As the deodorant mechanism of the lubricating deodorant composition according to the present embodiment, a chemical deodorant mechanism and a sensory deodorant mechanism can be considered. A chemical deodorizing mechanism is a mechanism that deodorizes by devolatizing, neutralizing, oxidizing/reducing, or decomposing malodorous components such as excrement. On the other hand, the sensuous deodorant mechanism is a mechanism that deodorizes by making the odor of excrement or the like inconspicuous by the scent of the deodorant component. As shown in the examples below, the lubricating deodorant composition according to the present embodiment is a lubricating deodorant composition containing only the component (A1) persimmon extract or only the component (B1) sugarcane extract (comparative example Compared to 1 and 2), it is also excellent in the effect of decomposing malodorous components (hydrogen sulfide gas) of excrement, etc., and is also excellent in the effect of making the odor of excrement difficult to perceive. As described above, the lubricating deodorant composition according to the present embodiment has a chemical deodorant mechanism and a sensory deodorant mechanism by combining the component (A1) persimmon extract and the component (B1) sugarcane extract. It is considered that the deodorizing effect is exerted and the deodorizing property against excrement and the like is improved.
本実施形態における成分(A1)柿抽出物及び成分(B1)サトウキビ抽出物の質量割合(A1)/(B1)は0.1~20であることが好ましく、1~10であることがより好ましい。成分(A1)及び成分(B1)の質量割合を上記範囲とすることによって、より効果的にオストミー装具の使用における消臭性と取扱性(便排出時の潤滑性)を向上させることができる。 The mass ratio (A1)/(B1) of component (A1) persimmon extract and component (B1) sugarcane extract in the present embodiment is preferably 0.1 to 20, more preferably 1 to 10. . By setting the mass ratio of the component (A1) and the component (B1) within the above range, it is possible to more effectively improve the deodorant property and handleability (lubricating property during excretion of feces) in the use of the ostomy appliance.
本実施形態における成分(C)親水性高分子化合物は、潤滑消臭剤組成物に対する増粘作用をもち、潤滑消臭剤組成物をオストミー装具のパウチ内表面に持続的に付着しやすくする。その結果、排泄物等とオストミー装具のパウチ内表面に付着した潤滑消臭剤組成物との間で潤滑効果を発揮し、排泄物等をパウチ内表面から除去する際の取扱性を向上することができる。また、親水性高分子化合物が排泄物等の悪臭成分を吸着することで、排泄物等に対する消臭効果を持続させることができる。 The component (C) hydrophilic polymer compound in the present embodiment has a thickening effect on the lubricating deodorant composition, and facilitates continuous adhesion of the lubricating deodorant composition to the inner surface of the pouch of the ostomy appliance. As a result, a lubricating effect is exhibited between the excrement, etc., and the lubricating deodorant composition adhering to the inner surface of the pouch of the ostomy appliance, and the handling property when removing the excrement, etc. from the inner surface of the pouch is improved. can be done. In addition, the hydrophilic polymer compound adsorbs malodorous components such as excrement, so that the deodorizing effect on excrement and the like can be maintained.
親水性高分子化合物としては、天然、半合成又は合成の親水性高分子化合物を用いることができる。なお、「半合成」とは、部分化学合成とも称され、例えば植物材料、微生物又は細胞培養物等の天然資源から単離された化合物を出発物質として使用する化学合成をいう。 As the hydrophilic polymer compound, a natural, semisynthetic or synthetic hydrophilic polymer compound can be used. The term "semi-synthesis" is also called partial chemical synthesis, and refers to chemical synthesis using, as starting materials, compounds isolated from natural resources such as plant materials, microorganisms, or cell cultures.
天然親水性高分子化合物の具体例としては、アラビアガム、トラガカントガム、ガラクタン、グアガム、キャロブガム、カラヤガム、カラギーナン、ペクチン、カンテン及びデンプン(例えば、コメ、トウモロコシ、バレイショ及びコムギのデンプン)等の植物系高分子;キサンタンガム、デキストリン、デキストラン、サクシノグルカン、マンナン、ローカストビーンガム及びプルラン等の微生物系高分子;コラーゲン、カゼイン、アルブミン及びゼラチン等の動物系高分子等が挙げられる。 Specific examples of natural hydrophilic polymer compounds include plant-based high-molecular compounds such as gum arabic, gum tragacanth, galactan, guar gum, carob gum, karaya gum, carrageenan, pectin, agar and starch (e.g., rice, corn, potato and wheat starch). Molecules; microbial polymers such as xanthan gum, dextrin, dextran, succinoglucan, mannan, locust bean gum and pullulan; animal polymers such as collagen, casein, albumin and gelatin;
半合成親水性高分子化合物の具体例としては、カルボキシメチルデンプン、メチルヒド
ロキシプロピルデンプン等のデンプン系高分子;メチルセルロース、エチルセルロース、メチルヒドロキシプロピルセルロース、ヒドロキシエチルセルロース、セルロース硫酸ナトリウム、ヒドロキシプロピルセルロース、カルボキシメチルセルロース、カルボキシメチルセルロースナトリウム等のセルロース系高分子;アルギン酸ナトリウム、アルギン酸カルシウム、アルギン酸プロピレングリコールエステル等のアルギン酸系高分子等が挙げられる。
Specific examples of semi-synthetic hydrophilic polymer compounds include starch-based polymers such as carboxymethyl starch and methylhydroxypropyl starch; methylcellulose, ethylcellulose, methylhydroxypropylcellulose, hydroxyethylcellulose, sodium cellulose sulfate, hydroxypropylcellulose, carboxymethylcellulose. , cellulose-based polymers such as sodium carboxymethylcellulose; alginic acid-based polymers such as sodium alginate, calcium alginate and propylene glycol alginate.
合成親水性高分子化合物の具体例としては、ポリビニルアルコール、ポリビニルメチルエーテル、ポリビニルピロリドン、カルボキシビニルポリマー等のビニル系高分子;ポリエチレングリコール、ポリオキシエチレン・ポリオキシプロピレン共重合体等のポリオキシエチレン系高分子;ポリアクリル酸ナトリウム、ポリアクリルアミド等のアクリル系高分子;ポリエチレンイミン等が挙げられる。 Specific examples of synthetic hydrophilic polymer compounds include vinyl polymers such as polyvinyl alcohol, polyvinyl methyl ether, polyvinylpyrrolidone and carboxyvinyl polymer; polyoxyethylenes such as polyethylene glycol and polyoxyethylene/polyoxypropylene copolymers; system polymers; acrylic polymers such as sodium polyacrylate and polyacrylamide; polyethyleneimine and the like.
本実施形態において、親水性高分子化合物は上記のうちから1種を単独で使用しても、2種以上を併用してもよい。これらの親水性高分子化合物のうち、カルボキシメチルセルロース、ヒドロキシエチルセルロース、ヒドロキシプロピルセルロース、ペクチン、カラヤガム、マンナン、ローカストビーンガム、及びゼラチンから選ばれる少なくとも1種を用いることが好ましく、カルボキシメチルセルロース、ヒドロキシエチルセルロース及びヒドロキシプロピルセルロースから選ばれる少なくとも1種を用いることがより好ましい。さらに、カルボキシメチルセルロースを用いることが特に好ましい。これらの親水性高分子化合物を潤滑消臭剤組成物に含有することにより、排泄物等とオストミー装具のパウチ内表面との間の潤滑性をより向上させることができる。 In this embodiment, the hydrophilic polymer compound may be used singly or in combination of two or more of the above hydrophilic polymer compounds. Among these hydrophilic polymer compounds, it is preferable to use at least one selected from carboxymethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, pectin, karaya gum, mannan, locust bean gum, and gelatin. It is more preferable to use at least one selected from hydroxypropyl cellulose. Furthermore, it is particularly preferred to use carboxymethylcellulose. By including these hydrophilic polymer compounds in the lubricating deodorant composition, the lubricity between excrement and the inner surface of the pouch of the ostomy appliance can be further improved.
本実施形態における成分(C)親水性高分子化合物は、潤滑消臭剤組成物中に0.05~4.5質量%の範囲で含有されていることが好ましく、0.1~3質量%含有されていることがより好ましい。親水性高分子化合物の含有量を上記範囲内とすることにより、潤滑消臭剤組成物をオストミー装具のパウチ内全体にまんべんなく持続的に付着させることができ、排泄物等をオストミー装具のパウチ内表面から除去する際の取扱性をさらに向上することができる。 The component (C) hydrophilic polymer compound in the present embodiment is preferably contained in the lubricating deodorant composition in the range of 0.05 to 4.5% by mass, and 0.1 to 3% by mass. It is more preferable that it is contained. By setting the content of the hydrophilic polymer compound within the above range, the lubricating deodorant composition can be evenly and continuously adhered to the entire pouch of the ostomy appliance, and excrement, etc. can be adhered to the pouch of the ostomy appliance. Handleability when removing from the surface can be further improved.
本実施形態における成分(D)水は、成分(C)親水性高分子化合物とともに潤滑消臭剤組成物に含有されることで、潤滑消臭剤組成物が適度な流動性を有するため、潤滑消臭剤組成物をオストミー装具のパウチ内全体にまんべんなく付着させることができる。その結果、排泄物等とオストミー装具のパウチ内表面に付着した潤滑消臭剤組成物との間で潤滑効果を発揮し、排泄物等をパウチ内表面から除去する際の取扱性を向上することができる。 The component (D) water in the present embodiment is contained in the lubricating deodorant composition together with the component (C) hydrophilic polymer compound, so that the lubricating deodorant composition has appropriate fluidity. The deodorant composition can be applied evenly throughout the pouch of the ostomy appliance. As a result, a lubricating effect is exhibited between the excrement, etc., and the lubricating deodorant composition adhering to the inner surface of the pouch of the ostomy appliance, and the handling property when removing the excrement, etc. from the inner surface of the pouch is improved. can be done.
本実施形態では水道水、常水、精製水等を用いることができ、精製水を用いることが好ましい。
また、本実施形態における成分(D)水は、潤滑消臭剤組成物中に76~94質量%の範囲で含有されていることが好ましく、80~90質量%含有されていることがより好ましい。
In this embodiment, tap water, ordinary water, purified water, etc. can be used, and purified water is preferably used.
In addition, the component (D) water in the present embodiment is preferably contained in the lubricating deodorant composition in the range of 76 to 94% by mass, more preferably 80 to 90% by mass. .
本実施形態に係る潤滑消臭剤組成物は、本発明の特徴を損なわない範囲で上記(A1)、(B1)、(C)及び(D)以外の任意成分を含有してもよい。任意成分としては、成分(E)着色料、上記成分(A1)及び(B1)以外の消臭成分、上記成分(C)以外の増粘剤、可溶化剤、保存料、香料等が挙げられる。 The lubricating deodorant composition according to the present embodiment may contain optional components other than (A1), (B1), (C) and (D) as long as they do not impair the characteristics of the present invention. Optional components include component (E) coloring agents, deodorant components other than the above components (A1) and (B1), thickeners other than the above component (C), solubilizers, preservatives, fragrances, and the like. .
成分(E)着色料は、化粧料等で通常用いられるものであれば特に限定されないが、例えば、酸化チタン、酸化セリウム、酸化アルミニウム、黄酸化鉄、黒酸化鉄、ベンガラ、
紺青、群青等の無機顔料;黄色4号、黄色5号、黄色401号、赤色226号、赤色201号、赤色202号、青色1号、青色404号等の有機顔料等が挙げられる。着色料を含有した潤滑消臭剤組成物がオストミー装具のパウチ部の色と互いに異色であることにより、オストミー装具のパウチ内全体にいきわたっているかを目視で容易に確認することができる。また、着色料を含有した潤滑消臭剤組成物がその保存容器の色と互いに異色であることにより、保存容器にどれだけ残っているかも目視で容易に確認することができる。
Component (E) coloring agent is not particularly limited as long as it is commonly used in cosmetics and the like. Examples include titanium oxide, cerium oxide, aluminum oxide, yellow iron oxide, black iron oxide, red iron oxide,
Inorganic pigments such as Prussian Blue and Ultramarine Blue; Organic pigments such as Yellow No. 4, Yellow No. 5, Yellow No. 401, Red No. 226, Red No. 201, Red No. 202, Blue No. 1 and Blue No. 404; Since the colorant-containing lubricating deodorant composition is different in color from the pouch portion of the ostomy appliance, it is possible to easily visually confirm whether or not the lubricating deodorant composition is spread throughout the pouch of the ostomy appliance. In addition, since the color of the lubricating deodorant composition containing the colorant is different from the color of the storage container, it is possible to easily visually confirm how much remains in the storage container.
上記成分(A1)及び(B1)以外の消臭成分の具体例としては、化学的消臭性化合物、生物学的消臭性化合物等が挙げられる。 Specific examples of deodorant components other than the components (A1) and (B1) include chemical deodorant compounds, biological deodorant compounds, and the like.
化学的消臭性化合物は、有機系消臭性化合物であっても無機系消臭性化合物であってもよい。有機系消臭性化合物の具体例としては、酢酸、シュウ酸、クエン酸、マロン酸、コハク酸、グルタル酸、フマル酸、リンゴ酸、酒石酸、マレイン酸、アクリル酸、乳酸、フタル酸、安息香酸、ニコチン酸等の有機酸若しくはその塩;(メタ)アクリル酸エステル、マレイン酸エステル等のエステル化合物;グリオキザール等のアルデヒド化合物;塩化ベンザルコニウム、塩化ベンゼトニウム、アルキルジアミノエチルグリシン塩酸塩等の第4級アンモニウム塩;等が挙げられる。一方、無機系消臭性化合物の具体例としては、炭酸ナトリウム、炭酸水素ナトリウム、炭酸カルシウム等の炭酸塩;酸化カルシウム、酸化マグネシウム、酸化アルミニウム、酸化亜鉛、酸化銅、酸化鉄、酸化チタン、ミョウバン等の金属酸化物;二酸化塩素等が挙げられる。 The chemical deodorant compound may be an organic deodorant compound or an inorganic deodorant compound. Specific examples of organic deodorant compounds include acetic acid, oxalic acid, citric acid, malonic acid, succinic acid, glutaric acid, fumaric acid, malic acid, tartaric acid, maleic acid, acrylic acid, lactic acid, phthalic acid, and benzoic acid. , Organic acids such as nicotinic acid or salts thereof; Ester compounds such as (meth)acrylic acid esters and maleic acid esters; Aldehyde compounds such as glyoxal; class ammonium salts; and the like. On the other hand, specific examples of inorganic deodorant compounds include carbonates such as sodium carbonate, sodium hydrogencarbonate, and calcium carbonate; calcium oxide, magnesium oxide, aluminum oxide, zinc oxide, copper oxide, iron oxide, titanium oxide, and alum. metal oxides such as; chlorine dioxide; and the like.
また、生物学的消臭性化合物の具体例としては、酵素、微生物(細菌、酵母)等の有機物分解作用を有する物質;エタノール、フェノキシエタノール、メチルパラベン、エチルパラベン、ブチルパラベン、プロピルパラベン等の防腐・殺菌作用を有する化合物等が挙げられる。 Further, specific examples of biological deodorant compounds include substances having an action to decompose organic substances such as enzymes and microorganisms (bacteria, yeast); Examples thereof include compounds having bactericidal activity.
本実施形態に係る潤滑消臭剤組成物は、25℃におけるpHが6~12の範囲であることが好ましく、7~11であることがより好ましく、7.5~10であることが特に好ましい。pHを上記範囲内にすることにより、排泄物等に対する消臭性を向上させながらも、皮膚刺激性を低減することができる。 The lubricating deodorant composition according to the present embodiment preferably has a pH in the range of 6 to 12 at 25 ° C., more preferably 7 to 11, and particularly preferably 7.5 to 10. . By adjusting the pH within the above range, it is possible to reduce skin irritation while improving deodorizing properties against excrement and the like.
本実施形態において、潤滑消臭剤組成物のpHは上記各成分の配合により調整され得るが、本発明の特徴を損なわない範囲で更にpH調整剤を用いて調整することもできる。
pH調整剤の具体例としては、クエン酸、酒石酸、マレイン酸、コハク酸、リンゴ酸、乳酸、アスコルビン酸等の有機酸若しくはその塩;水酸化ナトリウム、水酸化カリウム等のアルカリ金属水酸化物等が挙げられる。これらのpH調整剤は、潤滑消臭剤組成物中に0.05質量%以下で含有されていることが好ましく、0.01質量%以下で配合されていることがより好ましい。
In the present embodiment, the pH of the lubricating deodorant composition can be adjusted by blending the above components, but it can also be adjusted using a pH adjuster within a range that does not impair the features of the present invention.
Specific examples of pH adjusters include organic acids such as citric acid, tartaric acid, maleic acid, succinic acid, malic acid, lactic acid, and ascorbic acid, or salts thereof; alkali metal hydroxides such as sodium hydroxide and potassium hydroxide; is mentioned. The content of these pH adjusters in the lubricating deodorant composition is preferably 0.05% by mass or less, more preferably 0.01% by mass or less.
本実施形態に係る潤滑消臭剤組成物は、15~25℃における粘度が400~3,000mPa・sの範囲であることが好ましく、600~2,000mPa・sであることがより好ましく、800~1,800mPa・sであることが特に好ましい。粘度を上記範囲内にすることにより、潤滑消臭剤組成物が適度な流動性を有するため、潤滑消臭剤組成物をオストミー装具のパウチ内全体にまんべんなく付着させることができる。また、粘度を上記範囲内にすることにより、排泄物等とオストミー装具のパウチ内表面に付着した潤滑消臭剤組成物との間で潤滑効果を発揮し、排泄物等をパウチ内表面から除去する際の取扱性を向上することができる。なお、本実施形態における潤滑消臭剤組成物の粘度は、15~25℃において、B型粘度計を用い、ローター番号:3番、ローター回転数:12rpm、回転時間:10分の条件で測定することにより得られる値である。 The lubricating deodorant composition according to the present embodiment preferably has a viscosity at 15 to 25 ° C. in the range of 400 to 3,000 mPa s, more preferably 600 to 2,000 mPa s. It is particularly preferred to be up to 1,800 mPa·s. By setting the viscosity within the above range, the lubricating deodorant composition has appropriate fluidity, so that the lubricating deodorant composition can be evenly adhered to the entire pouch of the ostomy appliance. Further, by setting the viscosity within the above range, a lubricating effect is exhibited between the excrement, etc., and the lubricating deodorant composition adhering to the inner surface of the pouch of the ostomy appliance, and the excrement, etc. is removed from the inner surface of the pouch. It is possible to improve the handleability when doing. The viscosity of the lubricating deodorant composition in the present embodiment is measured using a Brookfield viscometer at 15 to 25° C. under the conditions of rotor number: 3, rotor rotation speed: 12 rpm, and rotation time: 10 minutes. is a value obtained by
本実施形態に係る潤滑消臭剤組成物は、常法に従って製造することができる。例えば、上記各成分を混合、溶解等させることによって製造することができる。
本実施形態に係る潤滑消臭剤組成物は、液状若しくは粘性を有する液状の組成物又は半流動体組成物として、ガラス製、プラスチック製等の保存容器に充填して提供され得る。
The lubricating deodorant composition according to this embodiment can be produced according to a conventional method. For example, it can be produced by mixing and dissolving the above components.
The lubricating deodorant composition according to the present embodiment can be provided as a liquid or viscous liquid composition or semi-fluid composition by filling a storage container made of glass, plastic or the like.
また、本実施形態に係る潤滑消臭剤組成物は、オストミー装具のパウチ内に注入又は噴霧等してオストミー装具のパウチ内表面に付着又はコーティングさせる。その方法は特に限定されないが、例えば、保存容器から直接オストミー装具のパウチ内に注入し、パウチ内全体に潤滑消臭剤組成物をいきわたらせて付着又はコーティングさせることができる。また、ポンプディスペンサー付き容器に充填し、オストミー装具のパウチ内にスプレーして付着又はコーティングさせることもできる。本実施形態に係る潤滑消臭剤組成物は、使用の都度、必要量をオストミー装具のパウチ内に添加してもよく、予め複数回使用可能な量をパウチ内に添加しておいてもよい。また、本実施形態に係る潤滑消臭剤組成物は、上記オストミー装具用に限らず、おむつ、尿パッド、生理用ナプキン、医療用吸収パッド等、比較的長時間にわたって人体に装着されるその他の排泄物等処理用品用としても有効に用いることができる。 In addition, the lubricating deodorant composition according to the present embodiment is injected or sprayed into the pouch of the ostomy appliance to adhere or coat the inner surface of the pouch of the ostomy appliance. Although the method is not particularly limited, for example, it can be directly injected into the pouch of the ostomy appliance from the storage container, and spread or coat the lubricating deodorant composition throughout the inside of the pouch. It can also be filled into a container with a pump dispenser and sprayed into the pouch of the ostomy appliance to adhere or coat. A necessary amount of the lubricating deodorant composition according to the present embodiment may be added to the pouch of the ostomy appliance each time it is used, or an amount that can be used multiple times may be added to the pouch in advance. . In addition, the lubricating deodorant composition according to the present embodiment is not limited to the above ostomy appliance, and can be used for diapers, urine pads, sanitary napkins, medical absorbent pads, etc., which are worn on the human body for a relatively long time. It can also be effectively used for disposal products such as excrement.
<第2実施形態>
本発明に係る第2実施形態の潤滑消臭剤組成物は、成分(A2)タンニン系化合物を含む消臭成分、成分(B2)スチルベン系化合物を含む消臭成分、成分(C)親水性高分子化合物及び成分(D)水を含有する。なお、上述した第1実施形態における成分(A1)柿抽出物及び成分(B1)サトウキビ抽出物以外の構成については、第1実施形態で説明した構成を同様に採用することができるため、本実施形態については説明を省略する。
<Second embodiment>
The lubricating deodorant composition of the second embodiment according to the present invention includes component (A2) a deodorizing component containing a tannin-based compound, component (B2) a deodorizing component containing a stilbene-based compound, and component (C) a highly hydrophilic It contains a molecular compound and component (D) water. In addition, since the configuration described in the first embodiment can be similarly adopted for the configuration other than the component (A1) persimmon extract and the component (B1) sugarcane extract in the above-described first embodiment, this embodiment Description of the form is omitted.
本実施形態における成分(A2)のタンニン系化合物は、化学構造によりカテコール系に属する縮合型タンニンとピロガロール系に属する加水分解性タンニンとに分類できる。縮合型タンニンの具体例としては、カキタンニン、ケブラチョタンニン、ミモザ(ワットル)タンニン、ガンビアタンニン、アカシアタンニン、カラマツタンニン、テアフラビン、テアルビジン等が挙げられる。一方、加水分解性タンニンの具体例としては、茶タンニン、チェストナット・タンニン、ミラボラムタンニン、オークタンニン、タラタンニン、五倍子タンニン、没食子タンニン等が挙げられる。本実施形態ではこれらのタンニン系化合物のうちから1種を単独で使用しても、2種以上を併用してもよい。また、本実施形態においては縮合型タンニンを含む消臭成分を用いることが好ましく、なかでもカキタンニンを含む消臭成分を用いることがより好ましい。 The tannin-based compound of component (A2) in the present embodiment can be classified into condensed tannins belonging to the catechol series and hydrolyzable tannins belonging to the pyrogallol series according to their chemical structures. Specific examples of condensed tannins include persimmon tannin, quebracho tannin, mimosa (wattle) tannin, gambia tannin, acacia tannin, larch tannin, theaflavin, and thearubigin. On the other hand, specific examples of hydrolyzable tannins include tea tannins, chestnut tannins, mirabolum tannins, oak tannins, cod tannins, quintuple tannins, and gallic tannins. In this embodiment, one of these tannin-based compounds may be used alone, or two or more may be used in combination. Moreover, in the present embodiment, it is preferable to use a deodorizing component containing condensed tannin, and it is more preferable to use a deodorizing component containing persimmon tannin.
また、本実施形態における成分(A2)タンニン系化合物を含む消臭成分は、植物から抽出等した植物由来の消臭成分であることが好ましい。植物由来の消臭成分の具体例としては、コーヒー、リンゴ、ブドウ、茶類(緑茶、焙じ茶、紅茶、ウーロン茶、マテ茶等)、柿、大豆、ピーナッツ、カカオ、ローズマリー、アロエ等由来のものが挙げられ、なかでも、柿由来の消臭成分であることが好ましい。 Further, the component (A2) deodorizing component containing a tannin-based compound in the present embodiment is preferably a plant-derived deodorizing component extracted from a plant. Specific examples of plant-derived deodorant ingredients include those derived from coffee, apples, grapes, teas (green tea, roasted tea, black tea, oolong tea, mate tea, etc.), persimmons, soybeans, peanuts, cacao, rosemary, aloe, etc. Among them, a persimmon-derived deodorizing component is preferable.
本実施形態における成分(A2)タンニン系化合物を含む消臭成分は、潤滑消臭剤組成物中に2.5~10質量%の範囲で含有されていることが好ましく、3~8質量%含有されていることがより好ましい。 The component (A2) of the deodorant component containing a tannin-based compound in the present embodiment is preferably contained in the lubricating deodorant composition in the range of 2.5 to 10% by mass, and contains 3 to 8% by mass. More preferably.
本実施形態における成分(B2)のスチルベン系化合物は、スチルベン及びその誘導体を包含する。また、本実施形態における成分(B2)スチルベン系化合物を含む消臭成分は、植物から抽出等した植物由来の消臭成分であることが好ましい。植物由来の消臭成分の具体例としては、サトウキビ、ブドウ、ピーナッツ、カカオ等由来のものが挙げられる。本実施形態ではこれらのスチルベン系化合物のうちから1種を単独で使用しても、2種
以上を併用してもよい。なかでも、サトウキビ由来の消臭成分を用いることが好ましい。
The stilbene-based compound of component (B2) in the present embodiment includes stilbene and derivatives thereof. Further, the deodorizing component containing the component (B2) stilbene-based compound in the present embodiment is preferably a plant-derived deodorizing component extracted from a plant. Specific examples of plant-derived deodorant components include those derived from sugar cane, grapes, peanuts, cacao, and the like. In this embodiment, one of these stilbene compounds may be used alone, or two or more may be used in combination. Among them, it is preferable to use a deodorizing component derived from sugarcane.
本実施形態における成分(B2)スチルベン系化合物を含む消臭成分は、潤滑消臭剤組成物中に0.05~10質量%の範囲で含有されていることが好ましく、0.1~5質量%含有されていることがより好ましい。 The component (B2) of the deodorant component containing the stilbene compound in the present embodiment is preferably contained in the lubricating deodorant composition in the range of 0.05 to 10% by mass, and 0.1 to 5 mass. % is more preferable.
本実施形態に係る潤滑消臭剤組成物は、成分(A2)タンニン系化合物を含む消臭成分と成分(B2)スチルベン系化合物を含む消臭成分とを組み合わせることによって、オストミー装具の使用における消臭性と取扱性(便排出時の潤滑性)を向上させることができる。
本実施形態に係る潤滑消臭剤組成物の消臭機構は、第1実施形態に係る潤滑消臭剤組成物と同様であると考えられる。すなわち、本実施形態に係る潤滑消臭剤組成物は、成分(A2)タンニン系化合物を含む消臭成分と成分(B2)スチルベン系化合物を含む消臭成分とを組み合わせることによって、化学的消臭機構及び感覚的消臭機構による消臭効果を発揮し、排泄物等に対する消臭性が向上していると考えられる。
The lubricating deodorant composition according to the present embodiment is a deodorant composition for use in an ostomy appliance by combining a deodorant component containing a tannin-based compound (A2) and a deodorant component containing a stilbene-based compound (B2). It is possible to improve odor and handleability (lubricity at the time of excretion of stool).
The deodorizing mechanism of the lubricating deodorant composition according to this embodiment is considered to be the same as that of the lubricating deodorant composition according to the first embodiment. That is, the lubricating deodorant composition according to the present embodiment is chemically deodorized by combining the deodorant component containing the component (A2) tannin compound and the deodorant component containing the component (B2) stilbene compound. It is considered that the deodorant effect is exhibited by the mechanism and the sensory deodorant mechanism, and the deodorant property for excrement and the like is improved.
本実施形態における成分(A2)タンニン系化合物を含む消臭成分及び成分(B2)スチルベン系化合物を含む消臭成分の質量割合(A2)/(B2)は0.1~20であることが好ましく、1~10であることがより好ましい。成分(A2)及び成分(B2)の質量割合を上記範囲とすることによって、より効果的にオストミー装具の使用における消臭性と取扱性(便排出時の潤滑性)を向上させることができる。 The mass ratio (A2)/(B2) of the component (A2) deodorizing component containing a tannin-based compound and the component (B2) deodorizing component containing a stilbene-based compound in the present embodiment is preferably 0.1 to 20. , 1-10. By setting the mass ratio of the component (A2) and the component (B2) within the above range, it is possible to more effectively improve the deodorant property and handleability (lubricating property during excretion of feces) in the use of the ostomy appliance.
以下、実施例に基づいて本発明を更に詳細に説明する。なお、以下に説明する実施例は、本発明の代表的な実施例の一例を示したものであり、これにより本発明の範囲が狭く限定されることはない。 The present invention will be described in more detail below based on examples. It should be noted that the examples described below are examples of representative examples of the present invention, and the scope of the present invention is not narrowly limited thereby.
表1に示した各成分を混合、溶解等させて潤滑消臭剤組成物を調製した。得られた潤滑消臭剤組成物について、以下に示す方法に従って評価を行った。
なお、柿抽出物としては、リリース科学工業株式会社製「パンシルFG-22」を用い、サトウキビ抽出物としては、三井製糖株式会社製「MSX-201」を用いた。また、親水性高分子化合物としては、カルボキシメチルセルロースは三晶株式会社製「CEKOL 30000」、ヒドロキシエチルセルロースは三晶株式会社製「SANHEC HH」、ヒドロキシプロピルセルロースは三晶株式会社製「NEOVISCO-MC RM30000S」を用いた。
A lubricating deodorant composition was prepared by mixing and dissolving each component shown in Table 1. The obtained lubricating deodorant composition was evaluated according to the method shown below.
As the persimmon extract, “Pancil FG-22” manufactured by Risu Kagaku Kogyo Co., Ltd. was used, and as the sugarcane extract, “MSX-201” manufactured by Mitsui Sugar Co., Ltd. was used. In addition, as hydrophilic polymer compounds, carboxymethyl cellulose is "CEKOL 30000" manufactured by Sansho Co., Ltd., hydroxyethyl cellulose is "SANHEC HH" manufactured by Sansho Co., Ltd., and hydroxypropyl cellulose is "NEOVISCO-MC RM30000S" manufactured by Sansho Co., Ltd. ” was used.
[潤滑消臭剤組成物のpH]
JIS Z8802に準拠して、校正したpH計電極を洗浄後、各潤滑消臭剤組成物のpHを3回測定し、平均値を求めた。
[pH of lubricating deodorant composition]
After cleaning the calibrated pH meter electrode according to JIS Z8802, the pH of each lubricating deodorant composition was measured three times, and the average value was obtained.
[潤滑消臭剤組成物の粘度]
各潤滑消臭剤組成物について、BLII型粘度計(東機産業社製)を用い、溶液温度:15~25℃、ローター番号:3番、ローター回転数:12rpm、回転時間:10分の条件で測定した。
[Viscosity of lubricating deodorant composition]
For each lubricating deodorant composition, using a BLII type viscometer (manufactured by Toki Sangyo Co., Ltd.), solution temperature: 15 to 25 ° C., rotor number: No. 3, rotor rotation speed: 12 rpm, rotation time: 10 minutes. measured in
[潤滑性評価]
排出口付きオストミー装具のパウチ内に各潤滑消臭剤組成物を約6g投入して全面に広げ、次いで、疑似便40gを投入した。オストミー装具のパウチを地面に対して垂直に30分間保持した後、排出口から疑似便を排出し、パウチ内の疑似便の残存の程度を評価した。潤滑消臭剤組成物を使用せずに疑似便40gのみをパウチ内に投入し、排出口から疑
似便を排出した時(以下、「未使用時」という)にパウチ内に残存する疑似便の量を基準として、以下の指標により評価を行った。以下の指標では、★の数が多いほど潤滑性に優れていることを示している。
★:未使用時よりも疑似便の残量がわずかに減少した
★★:未使用時よりも疑似便の残量が減少した
★★★:未使用時よりも疑似便の残量が大幅に減少した
なお、疑似便としては、ドッグフード(アイリスオーヤマ製「ヘルシーステッププラス1 角切りビーフ」)から大部分のグリセリンを除去した後の塊を潰したものを用いた。
[Lubricity evaluation]
About 6 g of each lubricating deodorant composition was put into the pouch of the ostomy appliance with an outlet, spread over the entire surface, and then 40 g of faeces was put. After holding the pouch of the ostomy appliance perpendicular to the ground for 30 minutes, the pseudo-stool was discharged from the outlet, and the extent of residual pseudo-stool in the pouch was evaluated. Only 40 g of pseudo feces was put into the pouch without using the lubricating deodorant composition, and when the pseudo feces was discharged from the outlet (hereinafter referred to as "unused time"), the amount of pseudo feces remaining in the pouch. Using the amount as a standard, evaluation was performed according to the following indices. In the following indices, the larger the number of stars, the better the lubricity.
★: The remaining amount of pseudo-stool was slightly less than when not in use ★★: The remaining amount of pseudo-stool was less than when not in use ★★★: The remaining amount of pseudo-stool was significantly lower than when not in use Diminished
As the pseudo-stool, dog food (“Healthy Step Plus 1 Cube Beef” manufactured by Iris Ohyama Co., Ltd.) was used after removing most of the glycerin and crushing lumps.
[硫化水素ガス消臭率]
オストミー装具に一般的に用いられる防臭性フィルムで作成したバッグの中に各潤滑消臭剤組成物を10g投入し、次いで、標準ガス発生機(ガステック社製「PD-1B-2」)を用いて発生させた硫化水素ガス300mLを入れた。その後、バッグの口を封止し、ガスと潤滑消臭剤組成物とが十分接触するようにバッグを外から揉んだ。30分静置後に、防臭性フィルム内の硫化水素ガス濃度をガス検知管(光明理化学工業社製「120SE」)にて測定し、以下の式によって消臭率(%)を算出した。
[Hydrogen sulfide gas deodorizing rate]
10 g of each lubricating deodorant composition was put into a bag made of a deodorant film commonly used for ostomy appliances, and then a standard gas generator ("PD-1B-2" manufactured by Gastech) was run. 300 mL of hydrogen sulfide gas generated using After that, the mouth of the bag was sealed and the bag was kneaded from the outside so that the gas and the lubricating deodorant composition were sufficiently in contact with each other. After standing still for 30 minutes, the hydrogen sulfide gas concentration in the deodorant film was measured with a gas detector tube ("120SE" manufactured by Komyo Rikagaku Kogyo Co., Ltd.), and the deodorant rate (%) was calculated according to the following formula.
[実便消臭性官能評価]
オストミー装具のパウチに各潤滑消臭剤組成物を約6g投入して全面に広げ、次いで、水道水で2倍希釈した人便を30g投入し、地面に対して垂直に保持した。2時間後、以下の指標により消臭性の評価を行った。
1:強烈な便臭がある
2:強い便臭がある
3:容易に便臭とわかる臭いがある
4:便臭とわかる臭いがあるが、弱い
5:臭気はあるが、便臭は感じない
[Real feces deodorant sensory evaluation]
About 6 g of each lubricating deodorant composition was added to the pouch of the ostomy appliance and spread over the entire surface, and then 30 g of human feces diluted twice with tap water was added and held vertically to the ground. After 2 hours, deodorant performance was evaluated according to the following indices.
1: Strong fecal odor 2: Strong fecal odor 3: Easily recognizable fecal odor 4: Mild odor recognizable as fecal odor 5: Odor but no fecal odor
[皮膚刺激性評価]
約0.05~0.1gの各潤滑消臭剤組成物を皮膚感作テスト用テープ(SmartPractice社製「フィンチャンバー」)の濾紙(φ8mm)に滴下し、被験者の上腕部内側に貼付し、その上からフィルムドレッシングで被覆して24時間放置した。その後、テスト用テープを剥がし、その時点から1時間、24時間後の皮膚状態を観察し、以下の指標により評価を行った。
○:1時間後及び24時間後において、紅斑なし
△:1時間後及び/又は24時間後において、非常に軽度な紅斑がある
×:1時間後及び/又は24時間後において、はっきりとした紅斑、中等度~高度の紅斑又は高度紅斑~わずかな痂皮がある
[Evaluation of skin irritation]
About 0.05 to 0.1 g of each lubricating deodorant composition was dropped on a filter paper (φ8 mm) of a tape for skin sensitization test ("Finn Chamber" manufactured by SmartPractice) and attached to the inside of the upper arm of the subject, It was then covered with a film dressing and allowed to stand for 24 hours. After that, the test tape was peeled off, and the skin condition was observed 1 hour and 24 hours after that point, and evaluated according to the following indices.
○: No erythema after 1 hour and 24 hours △: Very mild erythema after 1 hour and/or 24 hours ×: Clear erythema after 1 hour and/or 24 hours , moderate to severe erythema or severe erythema to slight crusting
表1に示すように、実施例の潤滑消臭剤組成物は、比較例の潤滑消臭剤組成物と比べて実便消臭性評価が良好であった。柿抽出物とサトウキビ抽出物とを組み合わせることにより、排泄物等の悪臭成分が分解等され、かつ排泄物等の臭いも感じにくくなるため、柿抽出物又はサトウキビ抽出物単独と比べて消臭性をより向上させることができると考えられる。オストミー装具の使用者にとって、排泄物等の臭いを感じにくくすることは重要な課題であるから、実便消臭性が高いことは、オストミー装具用の潤滑消臭剤組成物として特に有効であると考えられる。
さらに、実施例2~5、7は硫化水素ガス消臭率及び実便消臭性評価において特に優れていたことから、pHを本発明の好ましい範囲とすることで、消臭性をさらに向上させることができることがわかった。
また、実施例の潤滑消臭剤組成物は、[潤滑性評価]において基準とした「未使用時」の場合と比べて潤滑性評価が向上していたことから、排泄物等とオストミー装具のパウチ内表面との間の潤滑性に優れ、排泄物等をパウチ内表面から除去する際の取扱性が良好であることがわかった。なかでも、実施例5~7の潤滑消臭剤組成物は潤滑性評価が特に良好であったことから、親水性高分子化合物としてカルボキシメチルセルロースを用い、さらに粘度を本発明の好ましい範囲とすることで、さらに取扱性を向上させることができることがわかった。
さらに、実施例1と実施例2とを比較すると、柿抽出物の量が多いほど、消臭性や潤滑性が向上していた。このことから、柿抽出物を用いることは、消臭効果だけでなく、潤滑消臭剤組成物の潤滑性にも寄与しているのではないかと考えられる。
そのうえ、実施例の潤滑消臭剤組成物は、皮膚刺激性評価も良好であり、皮膚に対して刺激が少ないことがわかった。
As shown in Table 1, the lubricating deodorant compositions of the examples had better fecal deodorant evaluation than the lubricating deodorant compositions of the comparative examples. By combining the persimmon extract and the sugarcane extract, malodorous components such as excrement are decomposed, and the odor of excrement etc. becomes difficult to perceive, so that the persimmon extract or the sugarcane extract is more deodorizing than the persimmon extract or the sugarcane extract alone. can be further improved. For users of ostomy appliances, it is an important issue to make it difficult to smell excrement, etc. Therefore, high fecal deodorizing properties are particularly effective as lubricating deodorant compositions for ostomy appliances. it is conceivable that.
Furthermore, since Examples 2 to 5 and 7 were particularly excellent in the hydrogen sulfide gas deodorization rate and the feces deodorization evaluation, the pH is set to the preferred range of the present invention, thereby further improving the deodorization. I found that it can be done.
In addition, since the lubricating deodorant composition of the example had improved lubricity evaluation compared to the case of "unused" which was the standard in [lubricity evaluation], excrement etc. and the ostomy appliance It was found that the lubricating property with the inner surface of the pouch is excellent, and the handling property when excrement and the like is removed from the inner surface of the pouch is good. Among them, since the lubricating deodorant compositions of Examples 5 to 7 had particularly good lubricity evaluation, carboxymethyl cellulose was used as a hydrophilic polymer compound, and the viscosity was set within the preferred range of the present invention. , it was found that the handleability can be further improved.
Further, when comparing Example 1 and Example 2, the greater the amount of persimmon extract, the more improved the deodorant and lubricating properties. From this, it is considered that the use of the persimmon extract contributes not only to the deodorant effect but also to the lubricity of the lubricating deodorant composition.
Moreover, it was found that the lubricating deodorant compositions of Examples were also evaluated for good skin irritation, and were less irritating to the skin.
以上のとおり、本発明に係る潤滑消臭剤組成物は、成分(A1)柿抽出物、成分(B1)サトウキビ抽出物、成分(C)親水性高分子化合物及び成分(D)水を含有することによって、消臭性及び潤滑性を向上させることができる。換言すると、成分(A2)タンニン系化合物を含む消臭成分、成分(B2)スチルベン系化合物を含む消臭成分、成分(C)親水性高分子化合物及び成分(D)水を含有することによって、消臭性及び潤滑性を向上させることができる。 As described above, the lubricating deodorant composition according to the present invention contains component (A1) persimmon extract, component (B1) sugarcane extract, component (C) hydrophilic polymer compound, and component (D) water. Thereby, deodorizing properties and lubricating properties can be improved. In other words, by containing component (A2) a deodorizing component containing a tannin-based compound, component (B2) a deodorizing component containing a stilbene-based compound, component (C) a hydrophilic polymer compound, and component (D) water, Deodorant and lubricity can be improved.
Claims (10)
15~25℃における粘度が800~1,800mPa・sである、
オストミー装具用潤滑消臭剤組成物。
(A1)柿抽出物
(B1)サトウキビ抽出物
(C)カルボキシメチルセルロース
(D)水 containing the following components (A1), (B1), (C) and (D),
A viscosity of 800 to 1,800 mPa s at 15 to 25 ° C.
A lubricating deodorant composition for ostomy appliances.
(A1) persimmon extract (B1) sugarcane extract (C) carboxymethylcellulose (D) water
15~25℃における粘度が800~1,800mPa・sである、
オストミー装具用潤滑消臭剤組成物。
(A2)タンニン系化合物を含む消臭成分
(B2)スチルベン系化合物を含む消臭成分
(C)カルボキシメチルセルロース
(D)水 containing the following components (A2), (B2), (C) and (D),
A viscosity of 800 to 1,800 mPa s at 15 to 25 ° C.
A lubricating deodorant composition for ostomy appliances.
(A2) deodorant component containing tannin compound (B2) deodorant component containing stilbene compound (C) carboxymethyl cellulose (D) water
(A1)柿抽出物
(B1)サトウキビ抽出物
(C)親水性高分子化合物
(D)水 A lubricating deodorant composition for ostomy appliances containing the following components (A1), (B1), (C) and (D) and containing no carbonates or bicarbonates.
(A1) persimmon extract (B1) sugar cane extract (C) hydrophilic polymer compound (D) water
(A2)タンニン系化合物を含む消臭成分
(B2)スチルベン系化合物を含む消臭成分
(C)親水性高分子化合物
(D)水
A lubricating deodorant composition for ostomy appliances containing the following components (A2), (B2), (C) and (D) and containing no carbonates or bicarbonates.
(A2) Deodorant component containing tannin compound (B2) Deodorant component containing stilbene compound (C) Hydrophilic polymer compound (D) Water
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