JP2007202552A - 核酸における点変異及び／又は大規模変更をアッセイするための方法及び組成物、並びに遺伝疾病及び癌の診断におけるそれらの使用 - Google Patents

核酸における点変異及び／又は大規模変更をアッセイするための方法及び組成物、並びに遺伝疾病及び癌の診断におけるそれらの使用 Download PDF

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JP2007202552A
JP2007202552A JP2006336023A JP2006336023A JP2007202552A JP 2007202552 A JP2007202552 A JP 2007202552A JP 2006336023 A JP2006336023 A JP 2006336023A JP 2006336023 A JP2006336023 A JP 2006336023A JP 2007202552 A JP2007202552 A JP 2007202552A
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nucleic acid
acid fragment
sample
amplification
pcr
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JP2006336023A
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Japanese (ja)
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JP2007202552A5 (enExample
Inventor
Jean-Louis Viovy
ビオビー ジャン−ルイ
Claude Houdayer
ホダイエ クロード
Dominique Stoppa-Lyonnet
ストッパ−リヨネット ドミニク
Jeremie Weber
ウェバー ジェレミー
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Centre National de la Recherche Scientifique CNRS
Institut Curie
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Centre National de la Recherche Scientifique CNRS
Institut Curie
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Publication of JP2007202552A publication Critical patent/JP2007202552A/ja
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2006336023A 2005-12-13 2006-12-13 核酸における点変異及び／又は大規模変更をアッセイするための方法及び組成物、並びに遺伝疾病及び癌の診断におけるそれらの使用 Pending JP2007202552A (ja)

Applications Claiming Priority (1)

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EP05027186A EP1798291B1 (en) 2005-12-13 2005-12-13 Methods and compositions for assaying mutations and/or large scale alterations in nucleic acids and their uses in diagnosis of genetic diseases and cancers

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JP2007202552A true JP2007202552A (ja) 2007-08-16
JP2007202552A5 JP2007202552A5 (enExample) 2010-02-04

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JP2006336023A Pending JP2007202552A (ja) 2005-12-13 2006-12-13 核酸における点変異及び／又は大規模変更をアッセイするための方法及び組成物、並びに遺伝疾病及び癌の診断におけるそれらの使用

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US (1) US20070161032A1 (enExample)
EP (1) EP1798291B1 (enExample)
JP (1) JP2007202552A (enExample)
CN (1) CN1982477A (enExample)
AT (1) ATE510025T1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024111038A1 (ja) * 2022-11-22 2024-05-30 株式会社日立ハイテク 変異遺伝子検出方法

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005061728A1 (en) * 2003-12-16 2005-07-07 Institut Curie Methods and compositions for assaying mutations in nucleic acids
BR112012017532A2 (pt) * 2010-02-18 2019-09-24 Hoffmann La Roche "método para determinar um polipeptídeo com uma sequência de aminoácidos mutante, para produzir um poliptedo e uma imunoglobulina"
US20190139628A1 (en) * 2016-04-27 2019-05-09 Arc Bio, Llc Machine learning techniques for analysis of structural variants
CN110982887A (zh) * 2019-12-30 2020-04-10 上海健康医学院 用于lkb1基因突变检测的引物及其应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5885432A (en) * 1992-11-05 1999-03-23 Soane Biosciences Un-crosslinked polymeric media for electrophoresis
WO1995016910A1 (en) 1993-12-17 1995-06-22 Perkin-Elmer Corporation Uncharged polymers for separation of biomolecules by capillary electrophoresis
US5994075A (en) * 1996-05-17 1999-11-30 Hexagen Technology Limited Methods for identifying a mutation in a gene of interest without a phenotypic guide
EP0912766B2 (en) * 1996-06-04 2011-12-14 University of Utah Research Foundation Monitoring hybridization during pcr
US20020169309A1 (en) * 1997-08-05 2002-11-14 Gjerde Douglas T. Mutation detection method
WO1999023257A1 (en) * 1997-10-31 1999-05-14 Transgenomic, Inc. Method of detecting mutant dna by mipc and pcr
ATE310103T1 (de) * 1998-08-19 2005-12-15 Bioventures Inc Methode zur bestimmung von polynukleotidsequenzvariationen
DE69928688T2 (de) * 1998-12-09 2006-08-24 Massachusetts Institute Of Technology, Cambridge Verfahren zur identifizierung von punkt mutationen in einem genom
WO2001034839A1 (en) * 1999-11-12 2001-05-17 Dunlop Charles L M Approaches to identify genetic traits
FR2811083B1 (fr) 2000-06-30 2002-11-22 Inst Curie Milieu liquide non-thermosensible pour l'analyse d'especes au sein d'un canal
US20040018497A1 (en) * 2002-07-26 2004-01-29 Warden Craig H Human obesity LIPIN3 polynucleotide and polypeptide sequences and methods of use thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024111038A1 (ja) * 2022-11-22 2024-05-30 株式会社日立ハイテク 変異遺伝子検出方法
GB2639474A (en) * 2022-11-22 2025-09-24 Hitachi High Tech Corp Mutant gene detection method

Also Published As

Publication number Publication date
EP1798291B1 (en) 2011-05-18
ATE510025T1 (de) 2011-06-15
US20070161032A1 (en) 2007-07-12
EP1798291A1 (en) 2007-06-20
CN1982477A (zh) 2007-06-20

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