JP2007147449A - Test sheet - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a test sheet capable of simply determining stress or fatigue at a low cost. <P>SOLUTION: The test sheet has the transparent film 12 bonded to the skin a pressure-sensitive adhesive 26, the cobalt chloride paper 28, on which cobalt chloride is adsorbed, provided to the surface on the side of the pressure-sensitive adhesive 26 of the transparent film 12 and a hydrophobic nonwoven fabric 30 attached to the surface on the side opposite to the transparent film 12 of the cobalt chloride paper 28 A color sample 20 of colors developed by the hygroscopic reaction of cobalt chloride is printed of the transparent film 12 in the vicinity of the cobalt chloride paper 28. The cobalt chloride paper 28 is expressed as a change different in the reaction of cobalt chloride corresponding to different TEWL values (percataneous moisture evaporation amounts) before and after the presence boundary of stress. <P>COPYRIGHT: (C)2007,JPO&INPIT

Description

  The present invention relates to a test sheet for measuring mental and physical conditions such as fatigue, other stresses, the degree of relaxation, and a refreshing effect.

  Fatigue and other stresses are closely related to health in daily life, affect sympathetic and parasympathetic nerves, and change hormone balance. Stress can be mentally elevated or suppressed, and the heart can be throbbing, sweaty, tense, and the sympathetic nerve can be overworked, leaving it motivated, shortness of breath, high blood pressure, constipation・ It may cause irritation and insomnia. On the other hand, in the suppressed state, the heart rate is decreased, the blood vessels are dilated, and the sensory function is decreased, and the parasympathetic nerve is excessively activated.

  Usually, when there is excitatory stress, sweating occurs from a part of the body's sweat glands due to blood vessel contraction. As a result, the TEWL value (Trance Epidermal Water Loss, transdermal water evaporation, hereinafter simply referred to as TEWL value) increases. On the other hand, in the case of inhibitory stress or other fatigue, the blood vessel dilates and the TEWL value decreases. From this phenomenon, the degree of fatigue or other stress can be examined by measuring the TEWL value.

In the prior art, for the purpose of stress measurement, cortisol in saliva (increased when there is a lot of stress), immunoglobulin A (decrease when there is a lot of stress), amylase, etc., bioimpedance, skin surface temperature such as limbs A stress measuring device based on the above measurement has been proposed. Further, the chronic stress determination method and apparatus, recording medium, and determination sheet disclosed in Patent Document 1 measure salivary cortisol concentration, and whether or not the person may have chronic stress. It is the determination method which determines this. In addition, as a method for judging fatigue and other stresses, interviews by industrial physicians and the like and diagnosis by questionnaire surveys are also performed.
JP 2000-275248 A

  In the case of the conventional technology, the measuring device for each component is expensive or not easily available. Moreover, it was large and difficult to carry, and it could not be measured frequently. Accordingly, such a measuring device cannot be easily used at all times except for being installed in a clinic or a beauty salon. In addition, there are oral questioning methods (checklist method, interview method) by specialists, etc., which are cumbersome and time consuming.

  The present invention has been made in view of the problems of the prior art, and is simple, convenient, low-cost, and accurately determines the degree of fatigue that is excitatory stress or accumulative stress. The purpose is to provide a test sheet that can be used.

  The present invention includes a transparent film attached to the skin with an adhesive, a holder provided on the adhesive-side surface of the transparent film and adsorbing cobalt chloride, and a surface of the holder opposite to the transparent film A hydrophobic non-woven fabric attached to the transparent film, and a color sample printed near the holder of the transparent film and colored by absorption of moisture by the cobalt chloride. The holder is transdermal depending on the degree of stress. The test sheet is adjusted so that the degree of coloration of cobalt chloride changes corresponding to the amount of water evaporated.

  The holding body is a hygroscopic sheet, and the color sample is provided with a plurality of sections, and one section has a blue color close to anhydrous cobalt chloride and shows a low TEWL value in which the amount of transdermal moisture evaporation indicates an accumulative stress. In the other category, the light red and highest TEWL (transdermal moisture evaporation) when cobalt chloride completely absorbs moisture indicates excitatory stress. Further, the color sample can classify the degree of fatigue and stress into 3 to 10 levels by providing white, sky blue, light pink and the like in the middle of blue and light red in several stages.

  The test sheet of the present invention is in the form of an adhesive bandage, and the presence / absence, type, and degree of stress can be measured by a simple method of sticking to the body and checking the color change. Moreover, it is manufactured at a low cost, and it is possible to measure fatigue and other stresses anytime and anywhere through self-diagnosis. It is a measure of health management such as timing of breaks in daily life and sports activities, intake of nutrients, etc., promoting health Can be used.

  Hereinafter, embodiments of the present invention will be described with reference to the drawings. 1 and 2 show an embodiment of the present invention. A test sheet 10 according to this embodiment is provided with a transparent film 12 serving as an adhesive film, and the material thereof is made of a flexible resin having flexibility. It has been. For example, polyolefin, polypropylene, polyester, polyvinyl chloride, polyvinylidene chloride, polyethylene, nylon, urethane and the like are used. The thickness is 20 to 100 microns, preferably 50 to 75 microns. The transparent film 12 is cut into, for example, an oval shape.

  A predetermined pattern is printed on the surface 12 a of the transparent film 12. In the vicinity of the center of the surface 12a, an elongated rectangular picture portion 16 is formed along the longitudinal direction of the transparent film 12. The periphery of the pattern portion 16 may be printed with a solid color or the like, or may not be printed. At the center of the picture part 16, for example, two hexagonal transparent display parts 18 are arranged at right angles to the longitudinal direction of the picture part 16. The display unit 18 inside the pattern unit 16 is visible through the film 12 and can see the color of the cobalt chloride paper 28 described later.

  On both sides of the display unit 18 in the longitudinal direction, a color sample 20 of a cobalt chloride paper 28 described later is printed. A total of four color samples 20 are provided, one on each side of each display unit 18, formed into a long rectangle along the longitudinal direction of the pattern unit 16, and the color samples 20 parallel to each other are adjacent to each other. Yes.

  One or a plurality of cobalt chloride papers 28 are provided. By measuring with a plurality of sheets, discoloration is clear, and classification in 5 to 10 steps is possible, and the measurement accuracy is increased.

Swatches 20, first section 20a located at the lower left in the drawing of FIG. 1 is blue close to anhydrous salt of cobalt chloride, for example TEWL value indicates the fatigue is the accumulation of stress 3 mg / cm ² / hr or less. The second section 20b located in the upper left is a sky blue in which the moisture absorption of cobalt chloride has progressed, and the third section 20c located in the lower right is a white in which the moisture absorption has progressed more. The fourth section 20d located in the upper right is pink when cobalt chloride completely absorbs moisture, and for example, the TEWL value is 6 mg / cm ² / hr or more indicating excitability stress.

  Here, an experiment conducted on the relationship between the TEWL value and stress will be described. Changes in TEWL values of 12 subjects considered to be healthy (22-58 years old, 5 men, 7 women) were measured at each site for approximately 2 weeks. At the time of measuring the TEWL value, the state of mind and body such as relaxed state, fatigue and other stresses were examined by questionnaire survey.

  As a result, the TEWL value varies significantly depending on the part of the body, the palms and soles are particularly high, and there are few cheeks and arms. There are also individual differences. Therefore, it was found that the palm has a high TEWL value and is easy to observe.

  Therefore, for twelve male and female subjects of each age, the TEWL value was measured several times with a water transpiration measuring device, and the fatigue / stress level at that time was determined by a questionnaire. An example of this is shown in the graph of FIG. 55M is a 55-year-old man, 30F is a 30-year-old woman, 31M is a 31-year-old man, and 26F is a 26-year-old woman. As a result, when all the subjects had a high TEWL value, the degree of stress based on the questionnaire results increased, and the TEWL value decreased due to fatigue, indicating a correlation. Thus, it was confirmed that the degree of fatigue, which is excitatory stress or chronic stress, can be examined by measuring the TEWL value.

  Moreover, when the presence or absence of the difference of TEWL value for every measurement site | part of a human body was verified, there was a difference shown in Table 1. Therefore, from the viewpoint of ease of measurement and reactivity, the palm is most easily observed and preferable. The measurement site may be a forehead in addition to the palm by changing the reference numerical value.

Therefore, in the measurement with the palm, when the TEWL value is 3 mg / cm ² / hr or less, there is a high correlation with the feeling of fatigue, and the first section 20a of the color swatch 20 shows 3 mg indicating fatigue where the TEWL value is accumulative stress. It is printed in a color below / cm ² / hr. Further, when the TEWL value is 6 mg / cm ² / hr or more, the correlation with the excitability stress is high, and the fourth section 20d of the color sample 20 has a TEWL value of 6 mg / cm ² / hr or more indicating the excitability stress. Printed in color.

Incidentally, TEWL value daily healthy individuals, as shown in FIG. 4, is a highest 5.0 mg / cm 2 ^/ hr before and after on awakening, gradually decreases, lowest 4mg during evening / cm ² / It will be around hr. At this time, when there is excitatory stress, the TEWL value increases to 6 mg / cm ² / hr or more, and when fatigued, it tends to decrease to 3 mg / cm ² / hr or less. When there is no stress, it is 4-6 mg / cm ² / hr, but when stress accumulates and fatigues, the TEWL value decreases and 2-3 mg / cm ² / hr In some cases, it has been confirmed by the inventors' experiments that it is 6 mg / cm ² / hr or higher. Therefore, it is better to perform chronic physical condition measurements during normal times during which the mind and body are stable during the daytime, and to check the state of mind and body at that time by checking fatigue and stress each time. I can do it.

  Furthermore, the 1st description part 22 is printed in the edge part by the side of the 1st division 20a and the 2nd division 20b of the pattern part 16 of the test sheet 10 of this embodiment. The first explanation part 22 is marked with the words “stress accumulation type”, and arrows on the first section 20a and the second section 20b side have a start point near the second section 20b and an end point near the first section 20a. It is written. The background of the first explanation part 22 is blue. A second explanation part 24 is printed at the end of the pattern part 16 on the third section 20c and fourth section 20d side. In the second explanation part 24, “excitatory stress” is displayed as an example of determination, and arrows on the third section 20c and the fourth section 20d side have a start point near the third section 20c and an end point near the fourth section 20d. It is written. The background of the second explanation part 24 is pink.

  An adhesive 26 for forming an adhesive film is applied to the back surface 12 b of the transparent film 12. The material of the adhesive 26 is made of an acrylic adhesive or a synthetic rubber adhesive such as SIS.

A cobalt chloride paper 28 is attached to the adhesive 26 so as to cover the display unit 18 on the back surface 12 b of the transparent film 12. The cobalt chloride paper 28 is obtained by adsorbing a cobalt chloride aqueous solution on a hygroscopic sheet such as a filter paper and drying the cobalt chloride paper 28. The cobalt chloride is blue in anhydrous salt, and changes to pink when moisture is absorbed. Cobalt paper 28 is chloride, adsorbed moisture amount is discolored in the range of ^{30μg / cm 2 / hr~500μg / cm} 2 / hr, blue below 150μg / cm ² / hr, a light at 500μg / cm ² / hr or more red It has been adjusted to be. In the range of ^{200μg / cm 2 / hr~450μg / cm} 2 / hr, and gradually changes color from sky blue to white further pale pink. Thereby, if the sticking time is 1 minute to 5 minutes, the TEWL value can be measured in the range of 30 μg / cm ² / hr to 25 mg / cm ² / hr.

A hydrophobic nonwoven fabric 30 is laminated and attached to the surface of the cobalt chloride paper 28 opposite to the transparent film 12. The nonwoven fabric 30 is made of polyester, for example, and has a basis weight of 60 g / m ² . A release sheet 32 is bonded to the back surface 12 b of the transparent film 12 with an adhesive 26 so as to cover the cobalt chloride paper 28 and the nonwoven fabric 30. The two release sheets 32 that are formed to be half the length of the transparent film 12 cover the vicinity of the center from both ends, and the ends overlap each other near the center, which is a clue when the release sheet 32 is peeled off. . The test sheet 10 to which the release sheet 32 is attached is packaged and sealed in a bag such as a resin film.

  Next, the usage method of the test sheet 10 of this embodiment is demonstrated. First, the release sheet 32 is peeled from the test sheet 10 to expose the adhesive 26. And the test sheet 10 is affixed on a test subject's skin, for example, a palm. In addition, before sticking the test sheet | seat 10, the palm sweat etc. are wiped off. If you get wet by hand washing, dry it well. After sticking, it is left in that state for a predetermined time, for example, 3 minutes. At this time, the non-woven fabric 30 captures palm sweat that is generated, and the cobalt chloride paper 28 adsorbs the moisture to change the crystal structure of the cobalt chloride, which changes from blue to pink. The change in the color of the cobalt chloride paper 28 is observed from the display unit 18 and the color of the cobalt chloride paper 28 is compared with the color sample 20 to determine which one is closer to the first section 20a to the fourth section 20d. Check the status of.

  If the color of the cobalt chloride paper 28 is close to the first section 20a, it indicates that there is accumulative stress and that it is slightly tired. When it is close to the second section 20b, it indicates that there is little stress and the mind and body are stable and relaxed. A case close to the third section 20c indicates that there is a slight excitability stress, but there is no problem. When it is close to the fourth section 20d, it indicates that excitatory stress is large.

  It should be noted that the degree of stress determined by measuring the TEWL value with the test sheet 10 is an experiment that the correlation between the head impedance value measured with a commercially available stress measuring device and the value of the test sheet of the present invention is high. Has been confirmed.

  By using the test sheet of the embodiment of the present invention, it is possible to measure the physical and mental health condition in a short time (for example, 3 minutes). In particular, according to the test sheet 10 of this embodiment, the type and degree of the subject's stress can be easily examined, and the test can be easily performed regardless of the place or environment. Since the test sheet 10 is affixed to the skin and the color change of the display unit 18 is observed in comparison with the color sample 20, the operation is simple and the reproducibility is excellent. Since the change in the color of the cobalt chloride is observed from the display unit 18 and the degree of stress is simply determined from the TEWL value as compared with the color sample 20, the determination is also easy. Further, since the display unit 18 is adjacent to the color sample 20, it can be accurately compared with the color sample 20. The cobalt chloride paper 28 is covered with a non-woven fabric 30 and the non-woven fabric 30 comes into contact with the skin and efficiently captures moisture due to perspiration. Therefore, the TEWL value can be detected accurately. In addition, the test sheet 10 is disposable every time, is clean and simple, is inexpensive, and is an economically superior method. In addition, you can easily determine the degree of your own stress, check excessive stress and fatigue by knowing the type and degree of stress, reference rest, sleep, intake of nutrients, It can be used as a measure of health management, such as intake of nutrients, to promote health. In addition, the refreshing effect can be confirmed by comparing the stress state before and after use such as stress relief goods and health supplies.

Note that the test sheet of the present invention is not limited to the above embodiment. For example, since it can be diagnosed that there is fatigue when the TEWL value is 3 mg / cm ² / hr or less, the color sample describes several stages within a low TEWL value between the first division 20a and the second division 20b. It is good also as a test sheet which judges a degree. The color sample is printed in 3 to 6 stages, for example, large fatigue (blue), slightly fatigued (sky blue), and small fatigue (white), and the degree of fatigue is determined. The test site is the palm and forehead, and the application time is an appropriate time. This makes it possible to determine whether to take nutritional drinks or vitamins, and is effective for sales promotion. This was in good agreement with the results of the questionnaire method. At present, there are no commercially available devices for measuring fatigue, but for research purposes, diagnosis is made through questionnaire surveys or interviews with industrial physicians.

  In addition, according to this test sheet, self-diagnosis can be performed and determined more easily without selecting a place. Moreover, excessive fatigue and stress can be eliminated by measuring during work or sports. Furthermore, relaxation has the effect of improving the state of mind and body and increasing immune function. In addition, by using this test sheet as a stress measurement method for a person wearing a colostomy, it is possible to easily measure timely stress.

Since the TEWL value is 8 mg / cm ² / hr or more and it can be diagnosed that there is excitatory stress, the color sample describes several stages in the range where the TEWL value is high between the third division 20c to the fourth division 20d, A test sheet for judging only excitatory stress may be used. The color swatch is printed, for example, in 3 to 6 stages of high stress (pink) and slightly stressed (white) to determine the degree of excitatory stress. The test site is the palm and forehead, and the application time is an appropriate time. Currently, an apparatus for measuring excitatory stress is large and expensive, but according to the test sheet of the present invention, it can be easily determined at low cost.

  In addition, the test sheet of the present invention can be appropriately changed in shape, material, etc., and the design of the printed picture part can also be changed as appropriate. The number of color sample sections can also be changed. Further, a plurality of display units may be provided, and cobalt chloride paper adjusted so that the reaction rate may be different may be attached to each display unit. Thereby, it is possible to accurately determine the TEWL value based on the difference between the two reaction rates.

  In addition, when there is one test paper, it can be determined by the determination in Table 2 below as an example of measurement of fatigue-relaxation-stress.

  Similarly, in the case of measuring only the degree of fatigue-relaxation, it can be performed by the determination in Table 3 below.

  Furthermore, in the case of measuring only the stress-relaxation degree, it can be performed by the determination in Table 4 below.

  Further, when there are two test papers, it can be set so that the color of the test paper changes more clearly. For example, in the case of measurement of fatigue-relaxation-stress, one test paper A displays fatigue large-fatigue-relaxed states as (blue), (blue), (white), and the other test paper B In this case, the stressful state-stressed-relaxed state can be represented by (pink), (light pink), and (white).

It is a front view of the test sheet of one embodiment of this invention. It is a cross-sectional view of the test sheet of this embodiment. It is a graph which shows the relationship between fatigue / stress and a TEWL value. It is a graph which shows the time change of the day of a TEWL value.

Explanation of symbols

DESCRIPTION OF SYMBOLS 10 Test sheet 12 Transparent film 16 Picture part 18 Display part 20 Color sample 22 First description part 24 Second description part 26 Adhesive 28 Cobalt chloride paper 30 Non-woven fabric 32 Release sheet

Claims (5)

  A transparent film attached to the skin with an adhesive, a holder provided on the adhesive-side surface of the transparent film and adsorbing cobalt chloride, and attached to the surface of the holder opposite to the transparent film A hydrophobic non-woven fabric and a color sample printed in the vicinity of the holding body of the transparent film and colored by absorption of the cobalt chloride by moisture absorption are provided. The holding body has different transdermal moisture evaporation amounts depending on the degree of stress. Correspondingly, the test sheet is adjusted so that the degree of coloration of cobalt chloride is changed.   The test sheet according to claim 1, wherein the holding body is a hygroscopic sheet. The color sample is provided with a plurality of sections, and one section has a blue color close to anhydrous cobalt chloride and has a transdermal moisture evaporation of 3 mg / cm ² / hr or less indicating fatigue that is an accumulative stress. ^3. The classification according to claim 1 or 2, characterized in that the amount of transdermal water evaporation is 6 mg / cm ² / hr or more indicating excitability stress when cobalt chloride completely absorbs moisture. Test sheet. The test sheet according to claim 1, 2 or 3, wherein the application site is a palm or a forehead. 3. The test sheet according to claim 2, wherein the cobalt chloride hygroscopic sheet is provided with a plurality of sheets having different sensitivities.

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