KR20080046044A - Test patch - Google Patents

Abstract

A test patch is provided to measure a sort and an intensity of stress based on a change of a color by attaching the test patch to a body of a user as an adhesive plaster. A test patch includes a transparent film(12), an adhesive agent(26), a cobalt chloride(28), and a non-woven fabric(30). The transparent is attached to a skin by the adhesive agent. A supporting body absorbs the cobalt chloride which is designed on an adhesive agent plane of the transparent film. The non-woven fabric is attached to a plane of an opposite side of the transparent film. The cobalt chloride printed on the supporting body is designed by moisture absorption. The supporting body is adjusted by a change of a color of the cobalt chloride corresponding to an evaporation quantity of other moisture based on the intensity of the stress.

Description

Test Sheet {Test Patch}

1 is a front view of a test sheet of an embodiment of the present invention.

2 is a cross-sectional view of a test sheet of this embodiment.

3 is a graph showing the relationship between fatigue / stress and TEWL values.

4 is a graph showing the daily change of TEWL value.

 [Description of the code]

 10 Test Sheet

      12 transparencies

      16 patterns

      18 display

      20 color swatches

      22 First Explanation

      24 Second Explanation

      26 adhesive

      28 Cobalt Chloride Paper

      30 nonwovens

      32 Peeling Sheet

[1] The present invention relates to a test sheet for measuring the state of mind and body, such as fatigue and other stress, the degree of mental and mental stability, and stress relief effects.

[2] Fatigue and other stresses are closely related to health in daily life, affect sympathetic and parasympathetic nerves, and alter hormonal balance. Stress has a state of mental excitement and restraint, and in a state of excitement, the heart beats and sweats, and the nervous and sympathetic nerves become overly active. In addition, suppressed conditions can lead to diminished heart rate, enlarged blood vessels, decreased perceptual function, overactive parasympathetic nerves, and neglect, dizziness, discoloration, allergies, diarrhea, decreased vision, and lethargy. .

[3] Normally, when there is excitatory stress, sweat begins to come from the body's sweat glands due to the contraction of blood vessels. As a result, the TEWL value (Tranceepidermal Water Loss: transdermal moisture evaporation amount, hereinafter referred to as TEWL value) increases. In the case of inhibitory stress or other fatigue, on the contrary, blood vessels expand and TEWL levels go down. From these phenomena, it is possible to measure fatigue and other stress levels from where TEWL values are measured.

[4] Examples of techniques include the measurement of cortisol in fluids (increase if stress is high), immunoglobulin A (reduced if stress is high) amylase, measurement of biological impedance, skin surface temperature such as hands and feet Stress measuring apparatuses and the like have been proposed. The published chronic stress determination method, its apparatus, recording medium, and determination sheet are determination methods for determining whether or not a person is likely to have chronic stress by measuring the concentration of Gokisol in the sap. In addition, as a method of determining fatigue or other stress, diagnosis by interviews or surveys by doctors in the industry and the like is also made.

[5] In the case of the foregoing example, the measuring device for each component is expensive and not simply a usable item. And they are large in size, difficult to carry, and not often measurable. Therefore, such a measuring device cannot be simply used all the time except for installing in a clinic or a beauty salon. In addition, there are verbal questions (checklist method, interview method) by specialists, etc., but it is complicated and time-consuming.

[6] The present invention has been developed to improve the problems described in the above-described conventional technique, and provides a test sheet which can determine the degree of fatigue which is simple, convenient, inexpensive, and precisely excitatory stress or accumulative stress. For the purpose of

[7] The present invention adheres to a transparent film attached to the skin by means of a pressure-sensitive adhesive and a retaining body which adsorbs cobalt chloride designed on the adhesive side of the transparent film as described above, and a surface opposite to the transparent film described above of the aforementioned retaining body. The water-resistant nonwoven fabric and the above-mentioned transparent film were printed in the vicinity of the aforementioned prosthesis, and the above-described cobalt chloride was absorbed by the moisture-colored color sample. This test sheet is adjusted to change the degree of coloration of cobalt chloride in response to the water evaporation amount.

[8] The above-mentioned support body is a hygroscopic sheet, and the above-mentioned color sample is designed in multiple divisions. One is blue, which is close to anhydrous salt of cobalt chloride. The other distinction is light red when cobalt chloride is completely hygroscopic, and the highest TEWL (transdermal moisture evaporation) indicates excitatory stress. In addition, the color swatches can be classified into three to ten levels of fatigue or stress by designing the distinction between white, light blue, and deep pink in the middle of blue and pale red.

EMBODIMENT OF THE INVENTION Hereinafter, embodiment of this invention is described based on drawing. 1 and 2 show an embodiment of the present invention, in which the test sheet 10 of this embodiment is designed with a transparent film 12 to be an attached film, and the material is made of a transparent resin having flexibility. For example, polyolefin, polypropylene, polyester, polyvinyl chloride, polyvinylidene chloride, polyethylene, nylon, urethane and the like are used. It is 20 to 100 microns thick and 50 to 70 microns thick. For example, transparent film 12 is cut to elliptical shape.

[0010] A predetermined pattern is printed on the surface 12a of the transparent film 12. Near the center of the surface 12a is formed in a thin rectangular pattern 16 that extends over the long side of the transparent film 12. 16 may be printed as a plain lamp or not. At the center of the design 16, for example, two hexagonal transparent display sections 18 are designed to be parallel to each other at right angles to the longitudinal direction of the design 16. The inside of the display portion 18 in Fig. 16 is transparent to the film 12, and it is possible to see the color of the cobalt chloride paper 28 described later.

[11] Color samples 20 of cobalt chloride paper 28, which will be described later, are printed on both sides of the display unit 18 in the longitudinal direction. Four color samples 20 are designed, one on each side of each display unit 18, formed in a long rectangle extending in the long direction of the drawing 16, and parallel to each other.

[12] Cobalt chloride paper 28 was designed as one sheet or as a plurality of sheets. By measuring as a plurality of sheets, discoloration becomes clear, classification of 5 to 10 levels is possible, and measurement accuracy is high.

이하이다. 좌측위에 위치한 제2구분 20b는 염화코발트의 흡습이 진행된 하늘색이고, 우측하단에 위치한 제3구분 20c는 좀 더 흡습이 진행된 백색이다. 우측상단에 위치한 제4구분 20d는 염화코발트가 완전히 흡습했을 때의 핑크색이고, 예를 들어 TEWL수치가 흥분성의 스트레스를 표시하고

이상이다.[13] The color sample 20 shows fatigue in which the first segment 20a located at the lower left of the drawing in FIG. 1 is blue near anhydrous salt of cobalt chloride, for example, the TEWL value is cumulative stress.

It is as follows. The second section 20b located in the upper left is light blue in which moisture absorption of cobalt chloride has progressed, and the third section 20c located in the lower right is more white in which the moisture absorption proceeds. The fourth division 20d located on the upper right is pink when the cobalt chloride is completely absorbed. For example, the TEWL value indicates the excitatory stress.

That's it.

[14] Here, the experiment performed on the relationship between the TEWL value and the stress will be described. Changes in TEWL levels in 12 subjects (22 to 58 years old, 5 males and 7 females), who were considered healthy, were measured at each site for 2 weeks. When measuring the TEWL level, we surveyed the physical and mental states such as mental and physical stability, fatigue and other stresses.

[15] As a result, TEWL levels were slightly different depending on the part of the body, the palm of the hand was particularly high, and the cheeks and arms were low. There were also individual differences. Thus, the palms had high TEWL values and were easy to observe.

[16] Twelve male and twelve subjects of each age were measured by a quantitative measuring device of moisture at several times, and the fatigue / stress level was then determined by a questionnaire. An example thereof is shown in the graph of FIG. 55M refers to a 55 year old male, 30F refers to a 30 year old female, 31M refers to a 31 year old male, and 26F refers to a 26 year old female. As a result, when all the test subjects had high TEWL values, the stress level was increased according to the survey results, and the TEWL value was lowered due to fatigue. Correlation was acknowledged. From this, it was confirmed that by measuring the TEWL value, it was possible to determine the degree of excitatory stress or chronic stress fatigue.

[17] In addition, TEWL values were incorrect for each measurement site of the human body. As shown in Table 1, there were differences. Therefore, the palm was the easiest to observe from the ease of measurement and reactivity. In addition, a measurement part changes the reference value, and may be a cheek other than a palm.

[18] Table 1

Measuring area Average (mg // hr) forehead 1.17-11.71 cheek 1.41-4.10 Inside the forearm 0.64 ~ 3.55 Palm 2.10-16.10 sole 2.47-17.22

이하로는 피로감과 상관성이 색견본 20의 제1구분 20a는 TEWL수치가 축적성 스트레스인 피로를 표시하고

이하의 색이 인쇄되어있다. 또 한 , TEWL수치가

이상으로는 흥분성 스트레스와 의 상관성이 높고, 색견본 20의 제4구분 20d는 TEWL수치가 흥분성 스트레스를 표시하는

이상의 색으로 인쇄되어있다.[19] Therefore, in the palm of your hand, the TEWL value

In the following, the relationship between fatigue and correlation 20a of the color sample 20 indicates fatigue with a TEWL value that is cumulative stress.

The following colors are printed. Also, the TEWL value

As mentioned above, the correlation with the excitatory stress is high, and the fourth division 20d of the color sample 20 shows that the TEWL value indicates the excitatory stress.

It is printed in more colors.

전후이나, 서서히 감소하여 저녁때에는 제일 낮고

전후가 된다. 이때, 흥분성스트레스가 있으면 TEWL수치가

이상으로 증가되고 한편 피로해지면

이하로 감소하는 경향이 있다. 스트레스가 없는 상태로는

과

사이이기때문에 스트레스가 축적되고, 피로한 경우는 TEWL수치가 저하하여

과

사이이고, 흥분성 스트레스가 있는 경우에는

이상이 되는 것이 본발명자의 실험으로 확인 되었다. 따라서 만성적피로의 몸상태 측정은 하루중에 심신이 안정된 평상시의 시간대에 행하는 것이 좋으며 때때로 피로나 스트레스의 체크는 그것을 여러번행하는 것에 의하여 그때그때의 심신의 상태를 파악하는 것이 가능하다.[20] In addition, TEWL values for a healthy person's day are highest when they wake up in the morning, as shown in Figure 4.

Before and after, slowly decreasing,

It is before and after. At this time, if there is excitable stress, TEWL value

If you increase above and become tired

It tends to decrease below. In a state without stress

and

Stress builds up, and the TEWL value decreases when tired.

and

If you have excitatory stress

The abnormality was confirmed by the experiment of the present inventors. Therefore, it is good to measure the physical condition of chronic fatigue at the normal time when mind and body are stabilized during the day, and sometimes it is possible to check the state of mind and body at that time by checking it on several times.

[21] In total, the first description part 22 is printed at the end of the first division 20a and the second division 20b of the drawing 16 of the test sheet 10 of this experimental form. In the first description section 22, a letter of accumulated stress is written. On the first side 20a and the second side 20 side, an arrow is written near the first division 20a with the end point as the starting point near the second division 20b. The background of the first description section 22 is blue. The second description portion 24 is printed at the end of the third and second divisions 20c and 20d of FIG. In the second explanation section 24, an example of determination is indicated as excitation stress, and an arrow is written on the third section 20c and the fourth section 20d with the third section 20d near the fourth section 20d as the end point. The background of the second description section 24 is pink.

[22] On the back side 12b of the transparent film 12, a pressure-sensitive adhesive 26 is applied to form an adhesive film. The raw material of the adhesive 26 is an acrylic adhesive or synthetic rubber adhesives, such as SIS.

부터

의 범위로 변화하고,

이하로는 청색으로,

이상으로는 엷은 적색으로 되도록 조정되어있다.

에서

사이의 범위로서는 하늘색으로부터 백색또는 연한 핑크색으로 서서히 변색한다. 이것에 따라서 부착시간을 1분~5분간으로 하면 TEWL수치는

부터

의 범위로 측정이 가능하게 된다. [22] On the back side 12b of the transparent film 12, cobalt chloride paper 28 wrapped around the display unit 18 is attached to the adhesive 26. Cobalt chloride paper 28 is obtained by adsorbing an aqueous solution of cobalt chloride onto a hygroscopic sheet such as a thin, thin cloth or the like. When cobalt chloride is blue with anhydrous salt, the color changes to pink when absorbed. Cobalt chloride paper 28 has the amount of water

from

Changes to the range of,

In blue below,

It is adjusted so that it becomes pale red above.

in

As a range in between, it changes color gradually from light blue to white or light pink. According to this, if the attachment time is set to 1 to 5 minutes, the TEWL value is

from

Measurement is possible in the range of.

이다. 투명필름 12의 뒷면12b에는 염화코발트종이 28과 부직포 30을 감쌌으며, 박리쉬트32가 점착제 26에 의하여 맞춰 붙여져 있다. 박리쉬트32는 투명필름 12의 1/2의 길이로 형성된 2매가 양단부에서 중심 가까이로 각각 감싸고 중심 부근에서 끝부분의 한패가 상호중복되어 분리쉬트32를 분리할 때 손에 달라붙지 않게된다. 그리고 분리쉬트32가 부착된 시험쉬트 10은 수지필름등의 주머니에 포장되어 밀봉되어있다.[24] On the opposite side of the transparent film 12 of cobalt chloride paper 28, a water-resistant nonwoven fabric 30 is laminated. Nonwoven 30 is, for example, usually polyester

to be. Cobalt chloride species 28 and nonwoven fabric 30 were wrapped on the back side 12b of the transparent film 12, and the release sheet 32 was fitted with the adhesive 26. The peeling sheet 32 has two sheets of a length of 1/2 of the transparent film 12 wrapped around each other at both ends and close to the center. The test sheet 10 attached with the separation sheet 32 is sealed in a bag such as a resin film.

[25] The following describes how to use Test Sheet 10 of this experimental form. Peel sheet 32 was removed from test sheet 10 and pressure sensitive adhesive 26 was exposed. The test sheet 10 is attached to the subject's skin, for example, the palm of the hand. Wipe off the sweat on the palms before applying the test sheet 10. Wipe your hands and dry them well if they are wet. Leave on for about 3 minutes for a predetermined time. At this time, the nonwoven fabric 30 absorbs the sweat of the palms and the moisture is absorbed by the cobalt chloride 28 so that the crystal structure of cobalt chloride changes and changes from blue to pink. From the display unit 18, the color change of the cobalt chloride 28 was observed, and the color change of the cobalt chloride 28 was observed, and the color of the cobalt chloride 28 was compared with the color sample 20, and which one was close to the first division 20a to the fourth division 20d. Determine and check your stress.

[26] If the color of cobalt chloride 28 is close to the first division 20a, it indicates cumulative stress and slight fatigue. If it is close to the second classification 20b, there is little stress and the state of mind and body stability is indicated. In the case of close to the third division 20c, the degree of excitation is slightly increased but there is no problem. In case of close to the fourth division 20d, the case where the excitatory stress is large is indicated.

[27] It was confirmed by experiment that the degree of stress irradiated by the measurement of TEWL value by test sheet 10 had a high correlation between the value of tofu impedance measured by a commercial stress measuring device and the value of the test sheet of the present invention. .

[28] By using the test sheet of the embodiment of the present invention, it is possible to measure the state of mind and body health in a short time (for example, 3 minutes). In particular, according to the test sheet 10 of this embodiment, it is possible to simply find out the type and degree of stress of the subject, and it is possible to test simply regardless of the place or environment. The test sheet 10 is attached to the skin and the change of the color of the display unit 18 is observed compared with the color sample 20, so the operation is simple and the reproducibility is excellent. The color change of cobalt chloride was observed from the display unit 18 and compared with the color sample 20 to determine the degree of stress accurately from the TEWL value. In addition, since the display unit 18 is adjacent to the color sample 20, it is possible to accurately compare it with the color sample 20. Cobalt chloride 28 is wrapped in a nonwoven fabric 30, and since the nonwoven fabric 30 directly touches the skin, it can effectively collect moisture from sweating, so it is possible to accurately detect the TEWL value. In addition, since test sheet 10 is discarded after one company, it is a clean and simple method, and it is economical because it is cheap. In addition, it is possible to easily determine the degree of self stress, and by knowing the type and degree of stress, it is possible to check for excessive stress or fatigue to promote recreation, sleep, and nutrient intake, and to manage health by timing of rest and intake of nutrients. It is possible to contribute to the promotion of health because it helps. In addition, it is possible to check the effect of mental and physical stability by comparing the stress state before and after using the stress relief article or health care article.

이하로 피로가 있다고 진단이 가능하기 때문에 색 견본에는 제1구분 20a로부터 제2구분 20b사이의 정도의 TEWL수치가 낮은 범위로 여러단계를 기재하고 피로도를 판정하는 시험쉬트로 해도 좋다. 색 견본은 예를 들어 피로가 큼(청색), 약간피로가 있음(하늘색), 피로적음(백색)의 3내지 6단계로 인쇄하여 피로도를 판정한다. 시험부위는 손바닥이나 이마이고 부착시간은 적절한 시간으로 한다. 이것에 의하여 영양제 드링크나 비타민제를 섭취할 것인지를 판단하는 것이 가능하여 판매촉진에도 효과가 있다. 이것은 앙케이트법에 의한 결과와도 잘 일치한다. 현재 피로를 측정하는 기기는 별로 시판되고 있지 않지만 연구용으로는 앙케이트조사나 산업현장의 의사의 면접으로 진단이 행해지고 있다. [29] The test sheet of the present invention is not limited to the embodiment described above. For example, the TEWL value

Since it is possible to diagnose that there is fatigue below, the color swatch may be used as a test sheet for describing fatigue levels by describing various steps in a range where the TEWL value of the degree between the first division 20a and the second division 20b is low. The color swatch is printed in three to six steps, for example, high fatigue (blue), slight fatigue (light blue), and low fatigue (white) to determine the degree of fatigue. The test site is the palm or forehead, and the attachment time is appropriate. As a result, it is possible to determine whether to consume nutritional drinks or vitamins, which is effective in promoting sales. This is in good agreement with the results obtained by the questionnaire method. Fatigue measuring instruments are not currently available on the market, but for research purposes, diagnosis is conducted by questionnaire surveys or interviews with industrial doctors.

[30] According to the test sheet, self-diagnosis and judgment can be made more easily regardless of location. It is also possible to relieve excessive fatigue or stress by taking measurements during work or exercise. Therefore, calculating the state of mind and body by relaxation of mind and body state has an effect of increasing immune function. In addition, it is possible to easily measure stress at a suitable time by using this test sheet as a stress measuring method for a person equipped with a human-airport door. In addition, dogs and cats raised at home do not express their own stress or fatigue unlike humans, so an appropriate method for testing them has not been developed until now. It is possible to measure.

이상으로 흥분성 스트레스가 있다고 진단하는 것이 가능하므로 색 견본에는 제3구분 20c로부터 제4구분 20d사이의 정도의 TEWL수치가 높은 범위로 여러단계를 기재하고 흥분성 스트레스를 판정하는 시험쉬트로 해도 좋다. 예를들어, 색견본은 스트레스 큼(핑크색), 약간 스트레스 있음(백색)의 3내지 6단계로 인쇄하고 흥분성 스트레스의 정도를 판정한다. 시험부위는 손바닥이나 이마로써 적절한 시간으로 한다. 현재 흥분성 스트레스를 측정하는 장치는 대형으로 고가이지만, 본 발명쉬트에 의하면 저렴한 비용으로 간단하게 판정하는 것이 가능하다.[31] TEWL numbers

Since it is possible to diagnose that there is excitatory stress, the color swatch may be a test sheet for describing the excitatory stress by describing various steps in a range where the TEWL value of the third division 20c to the fourth division 20d is high. For example, color swatches can be printed in three to six steps: high stress (pink), slightly stressed (white), and determine the degree of excitatory stress. The test site shall be at the appropriate time with the palm or forehead. At present, the apparatus for measuring the excitatory stress is large and expensive, but according to the sheet of the present invention, it is possible to simply determine it at low cost.

In addition, the test sheet of the present invention can appropriately change the shape and the material, and the design of the printed pattern can also be appropriately changed. The number of divisions of color swatches can be changed. In addition, it is also possible to attach cobalt chloride paper having a plurality of display sections and adjusted to different reaction rates on each display section. This makes it possible to accurately measure the TEWL value because the two reaction rates are different.

In addition, in the case of one sheet of test paper, it is possible to carry out by the determination of Table 2 below as an example of the measurement of fatigue-steady state-stress.

[34] Table 2

condition Tired Fatigue Steady state Stressful Stressful The color of the test paper blue Sky blue White Light pink pink

[35] Table 3

condition Tired Fatigue Steady state The color of the test paper blue Sky blue White

[36] Table 4

condition Stressful Stressful Steady state The color of the test paper pink Light pink White

[37] It is also possible to set the color of the test paper to change more reliably when there are two test papers. For example, for the measurement of fatigue and steady state stress, test sheet A on one side is fatigued-fatigue-indicate the steady state in blue, light blue, and white, respectively, and test sheet B on the other side is stressed-stress-steady state Can be displayed in pink, light pink and white.

The test sheet of the present invention is a simple method of attaching the body in the form of a band-aid and seeing the change of color, and it is possible to measure the presence, the kind, and the degree of stress. At the same time, it is manufactured at an affordable price so that anytime, anywhere self-diagnosis can be used to measure fatigue and other stresses, and it is possible to use it to promote health by making it easy to take a break from daily life or sports activities, ingestion of nutrients and health care. Do.

Claims (5)

The transparent film adhered to the skin by the adhesive and the retaining body designed to adsorb the cobalt chloride designed on the attaching surface of the transparent film mentioned above, the transparent film mentioned in front of the aforementioned retaining body, and the water-resistant nonwoven fabric attached to the surface on the opposite side and the transparent mentioned above A sample of a color in which cobalt chloride, which had been printed on the retainer described in front of the film, was darkened by moisture absorption was designed. The above-mentioned support body is a test sheet, characterized in that the degree of coloration of cobalt chloride is changed in response to the amount of evaporation of other transdermal moisture according to the degree of stress. The test sheet according to claim 1, wherein the holding member described above is a hygroscopic sheet. The color swatches mentioned above are designed to be multi-divided, and one category is blue, which is close to anhydrous salt of cobalt chloride, indicating the fatigue of transdermal moisture evaporation.

The other part is pale red when cobalt chloride is completely absorbed, and the transdermal moisture evaporation shows excitatory stress.

The test sheet according to claim 1 or 2 above. Test sheet according to claim 1,2 and 3, characterized in that the attachment portion is palm or forehead. The test sheet according to claim 2, wherein the hygroscopic sheet of cobalt chloride described above is designed with different sensitivity.

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