JP2007126457A - 事前固定式組織カセット - Google Patents
事前固定式組織カセット Download PDFInfo
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- JP2007126457A JP2007126457A JP2006298137A JP2006298137A JP2007126457A JP 2007126457 A JP2007126457 A JP 2007126457A JP 2006298137 A JP2006298137 A JP 2006298137A JP 2006298137 A JP2006298137 A JP 2006298137A JP 2007126457 A JP2007126457 A JP 2007126457A
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- 238000003745 diagnosis Methods 0.000 description 7
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- 238000005516 engineering process Methods 0.000 description 1
- 239000008098 formaldehyde solution Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 238000012735 histological processing Methods 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 229940057995 liquid paraffin Drugs 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/0096—Casings for storing test samples
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M45/00—Means for pre-treatment of biological substances
- C12M45/22—Means for packing or storing viable microorganisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/36—Embedding or analogous mounting of samples
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/041—Connecting closures to device or container
- B01L2300/043—Hinged closures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/046—Function or devices integrated in the closure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0609—Holders integrated in container to position an object
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
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- General Physics & Mathematics (AREA)
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- Animal Behavior & Ethology (AREA)
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- Veterinary Medicine (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Heart & Thoracic Surgery (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Sampling And Sample Adjustment (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
【解決手段】第1の平坦な基準多孔質構造(116)及び第2の多孔質構造(128)は、その間で組織を固定するために、当接する位置に配置され、接触する位置又は接触しない位置にすることができる。
【選択図】図1
Description
102、102’ 穿孔構造
104、104’ 穿孔構造
116 多孔質構造
128 多孔質構造
130 多孔質膜
132 多孔質膜
135、135’ 伸展性ヒンジ
136、136’ 締め具
144、144’ 孔
146 境界標表示システム
148 四半部
150 ラベル
152、154、160 生検サンプル
162、164、166、168、182 スライド
172、172’ 生検サンプル
180、180’ 病巣
236 締め具構造
Claims (15)
- 組織を保持するためのカセットであって、
前記組織を支持するための第1の平坦な基準多孔質構造と、
圧縮抵抗を有する第2の多孔質構造を収容する内部領域を画定する第2の穿孔構造と、
を含んでなり、
前記第1の平坦な基準多孔質構造及び前記第2の多孔質構造が、その間に前記組織を固定するために当接する位置に配置され得ることを特徴とするカセット。 - 第2の圧縮抵抗を有する前記第1の平坦な基準多孔質構造を収容する内部領域を画定する第1の穿孔構造をさらに含んでなることを特徴とする請求項1に記載のカセット。
- 接合具が、前記第1の平坦な基準多孔質構造と前記第2の穿孔構造とを接合し、双方の前記構造を一体に圧縮して前記組織をその間に堅固に捕捉していることを特徴とする請求項1に記載のカセット。
- 前記接合具が、締め具及びヒンジを使用して前記第1の平坦な基準多孔質構造と前記第2の穿孔構造とを接合していることを特徴とする請求項3に記載のカセット。
- 前記第2の多孔質構造が、所定の圧縮抵抗をもたらす発泡体を含んでいることを特徴とする請求項1に記載のカセット。
- 前記第2の多孔質構造が、人為構造を引き起こさない多孔質膜を含んでいることを特徴とする請求項1に記載のカセット。
- 前記第1の平坦な基準多孔質構造の圧縮抵抗が、前記第2の多孔質構造の前記圧縮抵抗よりも大きいことを特徴とする請求項1に記載のカセット。
- 前記第1の平坦な基準多孔質構造及び前記第2の穿孔構造が、二枚貝型の形状を形成するように配置されていることを特徴とする請求項1に記載のカセット。
- 多孔質構造のうちの1つが、その上に記された境界標表示システムを有することを特徴とする請求項1に記載のカセット。
- 組織サンプルを保持するための方法であって、
前記生検サンプルを組織カセット内に配置するステップと、
前記組織カセットの平坦な基準表面に対して前記生検サンプルを平坦化させるように圧縮力を作用させるために、前記組織カセットの少なくとも一部を移動させるステップと、
を含んでなることを特徴とする方法。 - 前記組織サンプルが、前記組織カセット内に、前記組織サンプルの病巣の位置に対応する境界標表示システム上に配置されることを特徴とする請求項10に記載の方法。
- 患者からの前記組織サンプルの病巣の位置又は方向に対応して、前記境界標表示システム上にラベルを記すステップをさらに含むことを特徴とする請求項11に記載の方法。
- 前記組織カセットの移動が、前記組織カセットの一部を旋回軸の周りで回動させることによって生じることを特徴とする請求項10に記載の方法。
- 前記平坦な基準表面と圧縮性の多孔質構造との間で前記組織サンプルを平坦化するステップをさらに含んでなることを特徴とする請求項10に記載の方法。
- 組織を保持するためのカセットであって、
前記組織を支持するための第1の平坦な基準多孔質構造と、
圧縮抵抗を有する第2の多孔質構造と、
を含んでなり、
前記第1の平坦な基準多孔質構造及び前記第2の多孔質構造が、その間に前記組織を固定するために当接する位置に配置され得ることを特徴とするカセット。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US73254905P | 2005-11-02 | 2005-11-02 | |
US60/732,549 | 2005-11-02 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2007126457A true JP2007126457A (ja) | 2007-05-24 |
JP4750672B2 JP4750672B2 (ja) | 2011-08-17 |
Family
ID=37682746
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2006298137A Expired - Fee Related JP4750672B2 (ja) | 2005-11-02 | 2006-11-01 | 事前固定式組織カセット |
Country Status (4)
Country | Link |
---|---|
US (1) | US20070116612A1 (ja) |
EP (1) | EP1782737A1 (ja) |
JP (1) | JP4750672B2 (ja) |
CA (1) | CA2566024A1 (ja) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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JP2014182131A (ja) * | 2013-03-15 | 2014-09-29 | Leica Biosystems Nussloch Gmbh | 引込式部材を具備する組織カセット |
JP2016148675A (ja) * | 2012-01-10 | 2016-08-18 | ユーシー—ケア リミテッド. | 生物組織ハンドリング装置および方法 |
Families Citing this family (85)
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ATE471211T1 (de) | 2002-09-26 | 2010-07-15 | Biopath Automation Llc | Kassette und einbettanordnung, stufungsvorrichtungen und verfahren zur handhabung von gewebeproben |
US7179424B2 (en) * | 2002-09-26 | 2007-02-20 | Biopath Automation, L.L.C. | Cassette for handling and holding tissue samples during processing, embedding and microtome procedures, and methods therefor |
DK1552266T3 (en) | 2002-09-26 | 2016-02-08 | Biopath Automation Llc | Apparatus and methods for automatic handling and embedding of tissue samples |
US7927564B2 (en) * | 2005-12-19 | 2011-04-19 | Leica Biosystems Richmond, Inc. | Histological specimen cassette |
US8163252B2 (en) | 2005-12-30 | 2012-04-24 | Healthtronics Laboratory Solutions, Inc. | Kit for taking biopsies, autopsies, excisions, and resections and methods thereof |
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US7951345B2 (en) * | 2007-06-01 | 2011-05-31 | Lary Research & Development, Llc | Useful specimen transport apparatus with integral capability to allow three dimensional x-ray images |
US8118962B2 (en) * | 2007-12-27 | 2012-02-21 | Cytyc Corporation | Method and apparatus for spacing cellular matter in a cell block |
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EP1782737A1 (en) | 2007-05-09 |
JP4750672B2 (ja) | 2011-08-17 |
CA2566024A1 (en) | 2007-05-02 |
US20070116612A1 (en) | 2007-05-24 |
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