JP2006528208A - コンプリメント５ａ受容体阻害剤を使用する出血ショックの処置 - Google Patents

コンプリメント５ａ受容体阻害剤を使用する出血ショックの処置 Download PDF

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Publication number
JP2006528208A
JP2006528208A JP2006529441A JP2006529441A JP2006528208A JP 2006528208 A JP2006528208 A JP 2006528208A JP 2006529441 A JP2006529441 A JP 2006529441A JP 2006529441 A JP2006529441 A JP 2006529441A JP 2006528208 A JP2006528208 A JP 2006528208A
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JP
Japan
Prior art keywords
side chain
bleeding
shock
inhibitor
receptor
Prior art date
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Withdrawn
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JP2006529441A
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English (en)
Japanese (ja)
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JP2006528208A5 (enExample
Inventor
デニス・ダブリュー・ハーキン
トーマス・エフ・リンゼイ
スティーブン・エム・テイラー
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University of Queensland
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University of Queensland
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Application filed by University of Queensland filed Critical University of Queensland
Publication of JP2006528208A publication Critical patent/JP2006528208A/ja
Publication of JP2006528208A5 publication Critical patent/JP2006528208A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2006529441A 2003-05-15 2004-05-14 コンプリメント５ａ受容体阻害剤を使用する出血ショックの処置 Withdrawn JP2006528208A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2003902354A AU2003902354A0 (en) 2003-05-15 2003-05-15 Treatment of haemorrhagic shock
PCT/AU2004/000642 WO2004100975A1 (en) 2003-05-15 2004-05-14 TREATMENT OF HAEMORRHAGIC SHOCK USING COMPLEMENT 5a RECEPTOR INHIBITORS

Publications (2)

Publication Number Publication Date
JP2006528208A true JP2006528208A (ja) 2006-12-14
JP2006528208A5 JP2006528208A5 (enExample) 2007-04-19

Family

ID=31501223

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006529441A Withdrawn JP2006528208A (ja) 2003-05-15 2004-05-14 コンプリメント５ａ受容体阻害剤を使用する出血ショックの処置

Country Status (5)

Country Link
EP (1) EP1635857A1 (enExample)
JP (1) JP2006528208A (enExample)
AU (1) AU2003902354A0 (enExample)
CA (1) CA2557615A1 (enExample)
WO (1) WO2004100975A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5819730B2 (ja) 2008-12-22 2015-11-24 ケモセントリックス，インコーポレイティド Ｃ５ａＲアンタゴニスト
DK2585064T3 (en) 2010-06-24 2017-07-24 Chemocentryx Inc C5aR antagonists
JP6898229B6 (ja) 2014-09-29 2021-07-28 ケモセントリックス，インコーポレイティド Ｃ５ａＲアンタゴニスト製造における方法及び中間体
SG11201805828YA (en) 2016-01-14 2018-08-30 Chemocentryx Inc Method of treating c3 glomerulopathy
SG11201808625QA (en) 2016-04-04 2018-10-30 Chemocentryx Inc SOLUBLE C5aR ANTAGONISTS
KR102638253B1 (ko) 2017-05-31 2024-02-16 케모센트릭스, 인크. C5a 억제제로서의 6-5 융합 고리
JP7141129B2 (ja) 2017-05-31 2022-09-22 ケモセントリックス，インコーポレイティド Ｃ５ａ阻害剤としての５－５融合環
CN111741754A (zh) 2017-10-30 2020-10-02 凯莫森特里克斯股份有限公司 作为免疫调节剂的氘代化合物
MA51327A (fr) 2017-12-22 2021-05-26 Chemocentryx Inc Composés cycliques fusionnés en 5,5 à substitution diaryle, utilisés en tant qu'inhibiteurs du c5ar
MX2020006459A (es) 2017-12-22 2020-11-06 Chemocentryx Inc Compuestos de anillos fusionados 6,5 diaril sustituidos como inhibidores de c5ar.
ES2993034T3 (en) 2018-04-02 2024-12-20 Chemocentryx Inc Prodrugs of fused-bicyclic c5ar antagonists

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPO755097A0 (en) * 1997-06-25 1997-07-17 University Of Queensland, The Receptor agonist and antagonist

Also Published As

Publication number Publication date
CA2557615A1 (en) 2004-11-25
WO2004100975A1 (en) 2004-11-25
EP1635857A1 (en) 2006-03-22
AU2003902354A0 (en) 2003-05-29

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