JP2006523224A5 - - Google Patents
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- Publication number
- JP2006523224A5 JP2006523224A5 JP2006508920A JP2006508920A JP2006523224A5 JP 2006523224 A5 JP2006523224 A5 JP 2006523224A5 JP 2006508920 A JP2006508920 A JP 2006508920A JP 2006508920 A JP2006508920 A JP 2006508920A JP 2006523224 A5 JP2006523224 A5 JP 2006523224A5
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- composition
- vsv
- dna plasmid
- cytokine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000000427 antigen Substances 0.000 claims 22
- 102000036639 antigens Human genes 0.000 claims 22
- 108091007433 antigens Proteins 0.000 claims 22
- 108020004414 DNA Proteins 0.000 claims 19
- 241000711975 Vesicular stomatitis virus Species 0.000 claims 19
- 239000013612 plasmid Substances 0.000 claims 19
- 102000004127 Cytokines Human genes 0.000 claims 11
- 108090000695 Cytokines Proteins 0.000 claims 11
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 10
- 230000001105 regulatory effect Effects 0.000 claims 9
- 150000007523 nucleic acids Chemical group 0.000 claims 6
- 108091026890 Coding region Proteins 0.000 claims 5
- 230000002163 immunogen Effects 0.000 claims 5
- 230000028993 immune response Effects 0.000 claims 4
- 108091006027 G proteins Proteins 0.000 claims 3
- 102000030782 GTP binding Human genes 0.000 claims 3
- 108091000058 GTP-Binding Proteins 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 230000001939 inductive effect Effects 0.000 claims 3
- 108020004707 nucleic acids Proteins 0.000 claims 3
- 102000039446 nucleic acids Human genes 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 239000012634 fragment Substances 0.000 claims 2
- 230000004927 fusion Effects 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 230000010076 replication Effects 0.000 claims 2
- 241000894006 Bacteria Species 0.000 claims 1
- 241000233866 Fungi Species 0.000 claims 1
- 102000004457 Granulocyte-Macrophage Colony-Stimulating Factor Human genes 0.000 claims 1
- 108010017213 Granulocyte-Macrophage Colony-Stimulating Factor Proteins 0.000 claims 1
- 241000725303 Human immunodeficiency virus Species 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 241000713311 Simian immunodeficiency virus Species 0.000 claims 1
- 230000005867 T cell response Effects 0.000 claims 1
- 241000700605 Viruses Species 0.000 claims 1
- 239000013566 allergen Substances 0.000 claims 1
- 230000005875 antibody response Effects 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 244000045947 parasite Species 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 230000003362 replicative effect Effects 0.000 claims 1
- 230000002195 synergetic effect Effects 0.000 claims 1
- 210000004881 tumor cell Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45787603P | 2003-03-26 | 2003-03-26 | |
| US54673304P | 2004-02-23 | 2004-02-23 | |
| PCT/US2004/006089 WO2004093906A1 (en) | 2003-03-26 | 2004-03-23 | Immunogenic composition and methods |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011154426A Division JP5635950B2 (ja) | 2003-03-26 | 2011-07-13 | 免疫原性組成物および方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006523224A JP2006523224A (ja) | 2006-10-12 |
| JP2006523224A5 true JP2006523224A5 (enExample) | 2007-05-24 |
Family
ID=42828775
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006508920A Withdrawn JP2006523224A (ja) | 2003-03-26 | 2004-03-23 | 免疫原性組成物および方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20070134200A1 (enExample) |
| EP (1) | EP1605971B1 (enExample) |
| JP (1) | JP2006523224A (enExample) |
| CN (1) | CN1764474B (enExample) |
| AT (1) | ATE468859T1 (enExample) |
| AU (1) | AU2004231464B2 (enExample) |
| BR (1) | BRPI0408779A (enExample) |
| CA (1) | CA2517010C (enExample) |
| DK (1) | DK1605971T3 (enExample) |
| MX (1) | MXPA05008526A (enExample) |
| NZ (1) | NZ542652A (enExample) |
| PL (1) | PL1605971T3 (enExample) |
| WO (1) | WO2004093906A1 (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6861422B2 (en) | 2003-02-26 | 2005-03-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions |
| KR101059721B1 (ko) * | 2003-03-26 | 2011-08-29 | 와이어쓰 엘엘씨 | 면역원성 조성물 및 의약 |
| TW200613554A (en) * | 2004-06-17 | 2006-05-01 | Wyeth Corp | Plasmid having three complete transcriptional units and immunogenic compositions for inducing an immune response to HIV |
| DE102004029784A1 (de) | 2004-06-21 | 2006-01-05 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue 2-Benzylaminodihydropteridinone, Verfahren zur deren Herstellung und deren Verwendung als Arzneimittel |
| DE102004033670A1 (de) | 2004-07-09 | 2006-02-02 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Pyridodihydropyrazinone, Verfahren zu Ihrer Herstellung und Ihre Verwendung als Arzneimittel |
| US7728134B2 (en) | 2004-08-14 | 2010-06-01 | Boehringer Ingelheim International Gmbh | Hydrates and polymorphs of 4[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide, process for their manufacture and their use as medicament |
| US20060058311A1 (en) | 2004-08-14 | 2006-03-16 | Boehringer Ingelheim International Gmbh | Combinations for the treatment of diseases involving cell proliferation |
| US7759485B2 (en) | 2004-08-14 | 2010-07-20 | Boehringer Ingelheim International Gmbh | Process for the manufacture of dihydropteridinones |
| US20060074088A1 (en) | 2004-08-14 | 2006-04-06 | Boehringer Ingelheim International Gmbh | Dihydropteridinones for the treatment of cancer diseases |
| US20060035903A1 (en) | 2004-08-14 | 2006-02-16 | Boehringer Ingelheim International Gmbh | Storage stable perfusion solution for dihydropteridinones |
| EP1630163A1 (de) | 2004-08-25 | 2006-03-01 | Boehringer Ingelheim Pharma GmbH & Co.KG | Dihydropteridinonderivative, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
| DE102004058337A1 (de) | 2004-12-02 | 2006-06-14 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Herstellung von annelierten Piperazin-2-on Derivaten |
| WO2006110344A1 (en) * | 2005-04-07 | 2006-10-19 | Wyeth | Novel methods for inducing an immune response against human immunodefiency virus |
| US7439358B2 (en) | 2006-02-08 | 2008-10-21 | Boehringer Ingelheim International Gmbh | Specific salt, anhydrous and crystalline form of a dihydropteridione derivative |
| EP2185559A1 (en) | 2007-08-03 | 2010-05-19 | Boehringer Ingelheim International GmbH | Crystalline form of a dihydropteridione derivative |
| ES2533345T3 (es) | 2009-06-08 | 2015-04-09 | The University Of Western Ontario | Diferentes serotipos del virus de la estomatitis vesicular como vectores de expresión para regímenes de inmunización |
| CN109142721B (zh) * | 2009-09-29 | 2021-10-26 | 宾夕法尼亚大学理事会 | 用于诊断和治疗脑炎或癫痫的方法 |
| US8546566B2 (en) | 2010-10-12 | 2013-10-01 | Boehringer Ingelheim International Gmbh | Process for manufacturing dihydropteridinones and intermediates thereof |
| US9358233B2 (en) | 2010-11-29 | 2016-06-07 | Boehringer Ingelheim International Gmbh | Method for treating acute myeloid leukemia |
| LT2654785T (lt) * | 2010-12-22 | 2019-07-10 | Bayer Intellectual Property Gmbh | Sustiprintas galvijų imuninis atsakas |
| US9370535B2 (en) | 2011-05-17 | 2016-06-21 | Boehringer Ingelheim International Gmbh | Method for treatment of advanced solid tumors |
| WO2015011236A1 (en) | 2013-07-26 | 2015-01-29 | Boehringer Ingelheim International Gmbh | Treatment of myelodysplastic syndrome |
| BR112016019837A2 (pt) | 2014-02-28 | 2017-10-17 | Bayer Animal Health Gmbh | plasmídeos imunoestimuladores |
| CN106794240A (zh) * | 2014-03-01 | 2017-05-31 | 普罗菲克图斯生物科学股份有限公司 | 重组伊斯法罕病毒载体 |
| US9867831B2 (en) | 2014-10-01 | 2018-01-16 | Boehringer Ingelheim International Gmbh | Combination treatment of acute myeloid leukemia and myelodysplastic syndrome |
| CN108025062A (zh) | 2015-07-31 | 2018-05-11 | 拜耳动物保健有限责任公司 | 猪科动物物种中增强的免疫应答 |
| CN105567646B (zh) * | 2016-02-22 | 2019-01-01 | 浙江大学 | 分泌抗甘蔗花叶病毒单抗杂交瘤细胞株及其单抗应用 |
| CN113968907B (zh) * | 2020-07-22 | 2023-05-26 | 中国人民解放军军事科学院军事医学研究院 | 具有中和活性的抗尼帕病毒单克隆抗体及应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ192465A (en) * | 1978-12-22 | 1983-09-30 | Biogen Nv | Recombinant dna molecule comprising gene coding for polypeptide displaying hbv (hepatitis b virus) antigenicity usesthereof |
| US5703055A (en) * | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| US5593972A (en) * | 1993-01-26 | 1997-01-14 | The Wistar Institute | Genetic immunization |
| US7153510B1 (en) * | 1995-05-04 | 2006-12-26 | Yale University | Recombinant vesiculoviruses and their uses |
| WO2001082962A2 (en) * | 2000-04-27 | 2001-11-08 | Aventis Pasteur Limited | Immunizing against hiv infection |
| US20030021805A1 (en) * | 2001-05-29 | 2003-01-30 | Barber Glen N. | Generation of HCV-like particles and chimeric HCV virus |
| US20030044386A1 (en) * | 2001-07-11 | 2003-03-06 | Barber Glen N. | Recombinant VSV for the treatment of tumor cells |
-
2004
- 2004-03-23 DK DK04722764.0T patent/DK1605971T3/da active
- 2004-03-23 JP JP2006508920A patent/JP2006523224A/ja not_active Withdrawn
- 2004-03-23 EP EP04722764A patent/EP1605971B1/en not_active Expired - Lifetime
- 2004-03-23 AU AU2004231464A patent/AU2004231464B2/en not_active Expired
- 2004-03-23 PL PL04722764T patent/PL1605971T3/pl unknown
- 2004-03-23 BR BRPI0408779-8A patent/BRPI0408779A/pt not_active Application Discontinuation
- 2004-03-23 AT AT04722764T patent/ATE468859T1/de active
- 2004-03-23 US US10/550,313 patent/US20070134200A1/en not_active Abandoned
- 2004-03-23 MX MXPA05008526A patent/MXPA05008526A/es active IP Right Grant
- 2004-03-23 CA CA2517010A patent/CA2517010C/en not_active Expired - Lifetime
- 2004-03-23 NZ NZ542652A patent/NZ542652A/en unknown
- 2004-03-23 WO PCT/US2004/006089 patent/WO2004093906A1/en not_active Ceased
- 2004-03-23 CN CN2004800078180A patent/CN1764474B/zh not_active Expired - Lifetime
-
2012
- 2012-04-24 US US13/454,884 patent/US20120244113A1/en not_active Abandoned
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