JP2006515750A5 - - Google Patents
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- JP2006515750A5 JP2006515750A5 JP2004562588A JP2004562588A JP2006515750A5 JP 2006515750 A5 JP2006515750 A5 JP 2006515750A5 JP 2004562588 A JP2004562588 A JP 2004562588A JP 2004562588 A JP2004562588 A JP 2004562588A JP 2006515750 A5 JP2006515750 A5 JP 2006515750A5
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- Prior art keywords
- antibody
- seq
- multivalent
- construct
- antibody construct
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| HUE026303T2 (hu) | 2005-07-25 | 2016-06-28 | Emergent Product Dev Seattle | B-sejt csökkentés CD37-specifikus és CD20-specifikus kapcsoló molekulák alkalmazásával |
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| JP2010532764A (ja) * | 2007-07-06 | 2010-10-14 | トゥルビオン・ファーマシューティカルズ・インコーポレーテッド | C末端に配置された特異的結合性ドメインを有する結合性ペプチド |
| EP2626371A1 (en) * | 2007-07-31 | 2013-08-14 | MedImmune, LLC | Multispecific epitope binding proteins and uses thereof |
| KR100967623B1 (ko) * | 2008-02-22 | 2010-07-05 | 전남대학교산학협력단 | 림포톡신을 포함하는 자궁경부암 예방 또는 치료용 조성물 |
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| US9605058B2 (en) | 2012-05-01 | 2017-03-28 | Glaxosmithkline Llc | Antibodies against the CXC-ELR family of chemokines |
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| JP2018503399A (ja) * | 2015-01-14 | 2018-02-08 | コンパス セラピューティクス リミテッド ライアビリティ カンパニー | 多特異性免疫調節抗原結合構築物 |
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| US20210188990A1 (en) * | 2019-12-11 | 2021-06-24 | Cilag Gmbh International | Multispecific binding molecules comprising ltbr and edb binding domains and uses thereof |
| JP2024508207A (ja) | 2020-12-02 | 2024-02-26 | ブイアイビー ブイゼットダブリュ | がんに対する組み合わせ治療におけるltbrアゴニスト |
| WO2022117569A1 (en) | 2020-12-02 | 2022-06-09 | Oncurious Nv | A ccr8 antagonist antibody in combination with a lymphotoxin beta receptor agonist antibody in therapy against cancer |
| EP4508082A1 (en) | 2022-04-13 | 2025-02-19 | Vib Vzw | An ltbr agonist in combination therapy against cancer |
| WO2023218320A1 (en) * | 2022-05-11 | 2023-11-16 | Pfizer Inc. | Anti-lymphotoxin beta receptor antibodies and methods of use thereof |
| WO2025113643A1 (en) | 2023-12-01 | 2025-06-05 | Gilead Sciences Inc. | Anti-fap-light fusion protein and use thereof |
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| US669941A (en) * | 1898-12-17 | 1901-03-12 | Electric Axle Light & Power Company | Electric switch. |
| US5618920A (en) * | 1985-11-01 | 1997-04-08 | Xoma Corporation | Modular assembly of antibody genes, antibodies prepared thereby and use |
| US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5859205A (en) * | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| AU692146B2 (en) * | 1990-06-27 | 1998-06-04 | Biogen Idec Ma Inc. | Lymphotoxin-beta, lymphotoxin-beta complexes, pharmaceutical preparations and therapeutic uses thereof |
| US6312691B1 (en) * | 1996-01-26 | 2001-11-06 | Jeffrey L. Browning | Lymphotoxin-α/β complexes and anti-lympotoxin-β receptor antibodies as anti-tumor agents |
| KR100475492B1 (ko) * | 1995-01-26 | 2005-03-14 | 바이오겐 아이덱 엠에이 인코포레이티드 | 항종양제로서의 림프독소-α/β 복합체 및항-림프독소-β수용체 항체 |
| US5925351A (en) * | 1995-07-21 | 1999-07-20 | Biogen, Inc. | Soluble lymphotoxin-β receptors and anti-lymphotoxin receptor and ligand antibodies as therapeutic agents for the treatment of immunological disease |
| US7060667B1 (en) * | 1998-01-30 | 2006-06-13 | Biogen Idec Ma, Inc. | Treatment of follicular lymphomas using inhibitors of the LT pathway |
| TR200504220T2 (tr) * | 1998-12-17 | 2007-04-24 | Biogen Idec Ma Inc. | Aktif limfotoksin-beta reseptör imunoglobülin şimeAktif limfotoksin-beta reseptör imunoglobülin şimerik proteinlerinin yüksek düzey ifadesi ve saflaştrik proteinlerinin yüksek düzey ifadesi ve saflaştırılması için bir yöntem.ırılması için bir yöntem. |
| DK1272647T3 (en) * | 2000-04-11 | 2014-12-15 | Genentech Inc | Multivalent antibodies and uses thereof |
| WO2002003073A1 (en) * | 2000-06-30 | 2002-01-10 | Innogenetics N.V. | Differential diagnosis of neurological diseases |
| CA2420193A1 (en) * | 2000-08-24 | 2002-02-28 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
| AR035352A1 (es) * | 2000-10-13 | 2004-05-12 | Biogen Inc | Anticuerpos anti-lt-beta-r humanizados |
| US20030133939A1 (en) * | 2001-01-17 | 2003-07-17 | Genecraft, Inc. | Binding domain-immunoglobulin fusion proteins |
| US7576185B2 (en) * | 2002-03-05 | 2009-08-18 | Genentech, Inc. | PRO34128 antibodies |
| CN1678625A (zh) * | 2002-07-01 | 2005-10-05 | 比奥根艾迪克Ma公司 | 人源化抗淋巴毒素β受体的抗体 |
| RS20050481A (sr) * | 2002-12-20 | 2007-08-03 | Biogen Idec Ma Inc., | Agensi limfotoksin beta receptora u kombinaciji sa hemoterapeutskim agensima |
-
2003
- 2003-12-22 AU AU2003299984A patent/AU2003299984A1/en not_active Abandoned
- 2003-12-22 EP EP03800249A patent/EP1583503A4/en not_active Withdrawn
- 2003-12-22 JP JP2004562588A patent/JP2006515750A/ja active Pending
- 2003-12-22 CA CA002511013A patent/CA2511013A1/en not_active Abandoned
- 2003-12-22 WO PCT/US2003/041393 patent/WO2004058191A2/en not_active Ceased
- 2003-12-22 CN CNB2003801090429A patent/CN100473664C/zh not_active Expired - Fee Related
-
2005
- 2005-06-17 US US11/155,444 patent/US20060104971A1/en not_active Abandoned
- 2005-07-19 NO NO20053530A patent/NO20053530L/no not_active Application Discontinuation
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