JP2006511473A5 - - Google Patents

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Publication number
JP2006511473A5
JP2006511473A5 JP2004537651A JP2004537651A JP2006511473A5 JP 2006511473 A5 JP2006511473 A5 JP 2006511473A5 JP 2004537651 A JP2004537651 A JP 2004537651A JP 2004537651 A JP2004537651 A JP 2004537651A JP 2006511473 A5 JP2006511473 A5 JP 2006511473A5
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JP
Japan
Prior art keywords
component
contrast agents
activatable
discloses
prior
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2004537651A
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English (en)
Japanese (ja)
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JP2006511473A (ja
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Publication date
Priority claimed from US10/252,311 external-priority patent/US7303741B2/en
Application filed filed Critical
Publication of JP2006511473A publication Critical patent/JP2006511473A/ja
Publication of JP2006511473A5 publication Critical patent/JP2006511473A5/ja
Pending legal-status Critical Current

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JP2004537651A 2002-09-23 2003-08-11 蛍光染料及びｍｒｉ造影剤を含む二元機能造影剤 Pending JP2006511473A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/252,311 US7303741B2 (en) 2002-09-23 2002-09-23 Systems and methods for high-resolution in vivo imaging of biochemical activity in a living organism
PCT/US2003/025184 WO2004026344A1 (en) 2002-09-23 2003-08-11 Bifunctional contrast agent comprising a fluorescent dye and an mri contrast agent

Publications (2)

Publication Number Publication Date
JP2006511473A JP2006511473A (ja) 2006-04-06
JP2006511473A5 true JP2006511473A5 (enExample) 2006-09-28

Family

ID=31992929

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004537651A Pending JP2006511473A (ja) 2002-09-23 2003-08-11 蛍光染料及びｍｒｉ造影剤を含む二元機能造影剤

Country Status (6)

Country Link
US (2) US7303741B2 (enExample)
EP (1) EP1545629A1 (enExample)
JP (1) JP2006511473A (enExample)
CN (1) CN1684710A (enExample)
AU (1) AU2003259769A1 (enExample)
WO (1) WO2004026344A1 (enExample)

Families Citing this family (36)

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WO2003057175A2 (en) 2002-01-02 2003-07-17 Visen Medical, Inc. Amine functionalized superparamagnetic nanoparticles for the synthesis of bioconjugates and uses therefor
WO2005017539A2 (en) * 2003-08-14 2005-02-24 The General Hospital Corporation Imaging pathology
WO2005063304A2 (en) * 2003-12-24 2005-07-14 Board Of Regents, The University Of Texas_System Poly (l-glutamic acid) paramagnetic material complex and use as a biodegradable mri contrast agent
US8147805B2 (en) * 2005-01-05 2012-04-03 The Board of Regents of The University of T exas System Conjugates for dual imaging and radiochemotherapy: composition, manufacturing, and applications
WO2006074809A2 (en) 2005-01-13 2006-07-20 Cinvention Ag Composite materials containing carbon nanoparticles
FI20055653A7 (fi) * 2005-12-08 2007-06-09 Wallac Oy Leimausreagenssi
EP1973575B1 (en) 2005-12-22 2019-07-24 Visen Medical, Inc. Biocompatible fluorescent metal oxide nanoparticles
US20070148094A1 (en) * 2005-12-22 2007-06-28 Uzgiris Egidijus E Polymeric imaging agents and medical imaging methods
CA2650574A1 (en) * 2006-04-27 2007-11-08 Barnes-Jewish Hospital Detection and imaging of target tissue
DE102006021317B3 (de) * 2006-05-06 2007-10-11 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Verfahren und Fluoreszenzlichtmikroskop zum räumlich hochauflösenden Abbilden einer Struktur einer Probe
US20080154102A1 (en) * 2006-07-03 2008-06-26 Frangioni John V Intraoperative imaging methods
US7906106B2 (en) * 2007-06-27 2011-03-15 General Electric Company In vivo cell trafficking
US8021647B2 (en) 2007-06-29 2011-09-20 General Electric Company In vivo optical imaging
US8440168B2 (en) 2008-03-24 2013-05-14 The Board Of Regents Of The University Of Texas System Image-guided therapy of myocardial disease: composition, manufacturing and applications
WO2009121055A1 (en) * 2008-03-28 2009-10-01 Georgia Tech Research Corporation Reduced dye probes for the detection of radical oxygen species
US8758727B2 (en) * 2008-03-31 2014-06-24 University Of Louisville Research Foundation, Inc. Site specific fluorescence and contrast marker for same
WO2010062557A2 (en) * 2008-10-27 2010-06-03 University Of Virginia Patent Foundation Multimodal imaging of atherosclerotic plaque targeted to lox-1
CN102497803B (zh) 2009-05-05 2015-03-25 卢米托股份有限公司 用于散射介质中改进的扩散发光成像或者断层照相的系统、方法和发光标记物
CN101554481B (zh) * 2009-05-19 2011-04-13 泸州医学院附属医院 用于spect和mri的双功能显像剂及其制备方法
US20130039858A1 (en) * 2010-03-01 2013-02-14 University Of Florida Research Foundation, Inc. Nir materials and nanomaterials for theranostic applications
US8834846B2 (en) 2010-05-06 2014-09-16 Bruker Biospin Corporation Fluorescent NIRF activatable probes for disease detection
WO2012047841A2 (en) * 2010-10-04 2012-04-12 Nuovoprobe Ltd. System and method for electromagnetic imaging and therapeutics using specialized nanoparticles
KR101352342B1 (ko) * 2010-11-24 2014-02-17 서울대학교산학협력단 코어 물질과 쉘 물질 사이에 나노갭이 형성된 단일 나노입자 및 이의 제조방법
CN102167813B (zh) * 2011-01-19 2012-08-08 兰州大学 一种荧光示踪纳米磁共振成像造影剂
EP2494936A3 (en) * 2011-03-03 2012-09-19 Imris Inc. MR compatible optical viewing device for use in the bore of an MR magnet
JPWO2012128162A1 (ja) * 2011-03-18 2014-07-24 コニカミノルタ株式会社 画像診断用シリカナノ粒子、その製造方法、及び生体物質標識剤
CN102166365B (zh) * 2011-04-25 2012-10-24 东南大学 一种多模态碘油纳米乳造影剂的制备方法
CN102397562B (zh) * 2011-11-23 2012-11-28 南昌大学 一种由普鲁士蓝负载Gd3+的造影剂的制备方法
US9492571B2 (en) * 2012-06-01 2016-11-15 University Of Massachusetts Molecular probes for multimodality imaging and tracking of stem cells
WO2014178006A2 (en) * 2013-05-01 2014-11-06 Indian Institute Of Technology Madras Coated mesoflowers for molecular detection and smart barcode materials
KR101567157B1 (ko) * 2013-12-13 2015-11-09 경북대학교 산학협력단 Mri/fi 조영제 및 이의 제조방법
CN107406872B (zh) 2015-01-22 2023-03-28 里兰斯坦福初级大学理事会 用于标记动物组织的化合物、组合物及其应用
EP3601261A4 (en) 2017-03-30 2021-07-14 The Board of Trustees of the Leland Stanford Junior University CONTRAST AGENTS ACTIVATED BY A PROTEASE FOR IN VIVO IMAGING
CN107384385B (zh) * 2017-07-31 2020-10-30 中山大学 MR/FL双模态成像探针及其制备方法以及掺杂Ho碳量子点的用途
WO2020127154A1 (en) * 2018-12-18 2020-06-25 Bracco Imaging Spa Pharmaceutical compositions comprising gd-complexes and polyarylene additives
CN110665015A (zh) * 2019-10-23 2020-01-10 中山大学 一种肿瘤微环境响应型荧光/磁共振双模态成像探针

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US4899755A (en) * 1985-05-08 1990-02-13 The General Hospital Corporation Hepatobiliary NMR contrast agents
US5900228A (en) * 1996-07-31 1999-05-04 California Institute Of Technology Bifunctional detection agents having a polymer covalently linked to an MRI agent and an optical dye
US5832931A (en) * 1996-10-30 1998-11-10 Photogen, Inc. Method for improved selectivity in photo-activation and detection of molecular diagnostic agents
US6592847B1 (en) 1998-05-14 2003-07-15 The General Hospital Corporation Intramolecularly-quenched near infrared flourescent probes
US6083486A (en) * 1998-05-14 2000-07-04 The General Hospital Corporation Intramolecularly-quenched near infrared fluorescent probes
US6217848B1 (en) * 1999-05-20 2001-04-17 Mallinckrodt Inc. Cyanine and indocyanine dye bioconjugates for biomedical applications
IT1318485B1 (it) * 2000-04-21 2003-08-25 Bracco Spa Uso di derivati di acidi biliari coniugati con complessi di ionimetallici nella visualizzazione diagnostica di sistemi microvascolari

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