JP2006508124A - 低酸素誘導性因子に関連した病状を治療するためのメルファレンのｎ−オキシドと誘導体 - Google Patents
低酸素誘導性因子に関連した病状を治療するためのメルファレンのｎ−オキシドと誘導体 Download PDFInfo
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| WO2009102960A1 (en) * | 2008-02-15 | 2009-08-20 | Board Of Regents Of The University Of Texas System | Compositions and methods for treating lung cancer |
| WO2012058325A1 (en) * | 2010-10-29 | 2012-05-03 | Oncothyreon Inc. | Compounds and methods useful for treatment of diseases mediated by hif-1 |
| WO2012082765A2 (en) | 2010-12-16 | 2012-06-21 | The United State Of America. As Represented By The Secretary Department Of Health And Human Services | Methods for decreasing body weight and treating diabetes |
| ES2896882T3 (es) | 2014-02-03 | 2022-02-28 | Quadriga Biosciences Inc | Beta-aminoácidos beta sustituidos y análogos como agentes quimioterapéuticos |
| WO2015117146A1 (en) | 2014-02-03 | 2015-08-06 | Quadriga Biosciences, Inc. | Beta-substituted gamma-amino acids and analogs as chemotherapeutic agents |
| US10349839B2 (en) * | 2015-02-27 | 2019-07-16 | Biotronik Se & Co. | Implantable pressure sensor device |
| CN108026026B (zh) | 2015-08-03 | 2021-02-09 | 夸德里加生物科学公司 | 作为化疗剂的β-取代的β-氨基酸和类似物及其应用 |
| EP4512819A3 (en) | 2015-08-12 | 2025-08-06 | The General Hospital Corporation | Compositions and methods that promote hypoxia or the hypoxia response for treatment and prevention of mitochondrial dysfunction and oxidative stress disorders |
| WO2018160772A1 (en) | 2017-02-28 | 2018-09-07 | The United State Of America, As Represented By The Secretary, Department Of Health & Human Services | Method of treating obesity, insulin resistance, non-alcoholic fatty liver disease including non-alcoholic steatohepatitis |
| WO2020146758A1 (en) | 2019-01-10 | 2020-07-16 | The General Hospital Corporation | Methods to treat mitochondrial-associated dysfunctions or diseases |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5602278A (en) * | 1994-10-20 | 1997-02-11 | Kirkpatrick; Lynn | N-oxides and derivatives of chlorambucil for treating hypoxic tumor cells |
-
2002
- 2002-11-06 US US10/288,888 patent/US20040087556A1/en not_active Abandoned
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2003
- 2003-11-03 WO PCT/US2003/035226 patent/WO2004043359A2/en not_active Ceased
- 2003-11-03 EP EP03768672A patent/EP1567476A4/en not_active Withdrawn
- 2003-11-03 JP JP2004551738A patent/JP2006508124A/ja active Pending
- 2003-11-03 AU AU2003291282A patent/AU2003291282B2/en not_active Ceased
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- 2003-11-03 CA CA2504496A patent/CA2504496C/en not_active Expired - Fee Related
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2004
- 2004-08-30 US US10/929,156 patent/US7399785B2/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5602278A (en) * | 1994-10-20 | 1997-02-11 | Kirkpatrick; Lynn | N-oxides and derivatives of chlorambucil for treating hypoxic tumor cells |
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| EP1567476A2 (en) | 2005-08-31 |
| EP1567476A4 (en) | 2008-09-24 |
| WO2004043359A3 (en) | 2004-09-10 |
| MXPA05004845A (es) | 2005-10-05 |
| WO2004043359B1 (en) | 2004-10-28 |
| CA2504496C (en) | 2010-05-04 |
| AU2003291282A1 (en) | 2004-06-03 |
| WO2004043359A2 (en) | 2004-05-27 |
| CA2504496A1 (en) | 2004-05-27 |
| AU2003291282B2 (en) | 2010-11-11 |
| US7399785B2 (en) | 2008-07-15 |
| US20050026872A1 (en) | 2005-02-03 |
| US20040087556A1 (en) | 2004-05-06 |
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